| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_10130 | | 23S rRNA pseudouridine(955/2504/2580) synthase RluC | 1.0 | CSW01_11550 | | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | 0.56 | 1 |
| Shewanella sp. ANA-3 | 0.61 | Shewana3_2566 | | ribosomal large subunit pseudouridine synthase C (RefSeq) | 0.71 | Shewana3_1098 | | GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase (RefSeq) | low | > 73 |
| Shewanella loihica PV-4 | 0.60 | Shew_1594 | | RluA family pseudouridine synthase (RefSeq) | 0.72 | Shew_1189 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase (RefSeq) | low | > 60 |
| Shewanella amazonensis SB2B | 0.60 | Sama_1988 | | pseudouridylate synthase (RefSeq) | 0.73 | Sama_1018 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase (RefSeq) | low | > 62 |
| Alteromonas macleodii MIT1002 | 0.57 | MIT1002_01725 | | Ribosomal large subunit pseudouridine synthase C | 0.66 | MIT1002_02698 | | Riboflavin biosynthesis protein RibBA | — | — |
| Kangiella aquimarina DSM 16071 | 0.50 | B158DRAFT_1770 | | ribosomal large subunit pseudouridine synthase C (EC 5.4.99.24) | 0.63 | B158DRAFT_1912 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase | — | — |
| Pseudomonas sp. BP01 | 0.50 | JOY50_RS16830 | rluC | 23S rRNA pseudouridine(955/2504/2580) synthase RluC | 0.54 | JOY50_RS04730 | ribBA | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | low | > 84 |
| Pseudomonas stutzeri RCH2 | 0.50 | Psest_1680 | | pseudouridine synthase, RluA family | 0.50 | Psest_3550 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase | — | — |
| Pseudomonas sp. S08-1 | 0.50 | OH686_22095 | | LSU rRNA pseudouridine(955/2504/2580) synthase | 0.51 | OH686_15705 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II | low | > 80 |
| Pseudomonas putida KT2440 | 0.50 | PP_1906 | | ribosomal large subunit pseudouridine synthase C | 0.54 | PP_3813 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II | low | > 96 |
| Marinobacter adhaerens HP15 | 0.49 | HP15_2221 | | pseudouridine synthase, RluA family | 0.56 | HP15_493 | | bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein | — | — |
| Pseudomonas sp. SVBP6 | 0.49 | COO64_RS05845 | rluC | 23S rRNA pseudouridine(955/2504/2580) synthase RluC | 0.51 | COO64_RS15880 | ribBA | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | low | > 93 |
| Pseudomonas segetis P6 | 0.49 | MPMX49_02072 | | Ribosomal large subunit pseudouridine synthase C | 0.50 | MPMX49_00992 | | Riboflavin biosynthesis protein RibBA | low | > 75 |
| Pseudomonas sp. RS175 | 0.49 | PFR28_03018 | | Ribosomal large subunit pseudouridine synthase C | 0.50 | PFR28_03947 | | Riboflavin biosynthesis protein RibBA | low | > 88 |
| Pseudomonas aeruginosa PA14 | 0.48 | IKLFDK_15135 | | 23S rRNA pseudouridine(955/2504/2580) synthase RluC | 0.52 | IKLFDK_20900 | | bifunctional 3 4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | low | > 100 |
| Pseudomonas fluorescens FW300-N2E2 | 0.48 | Pf6N2E2_5944 | | Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) | 0.49 | Pf6N2E2_4921 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25) | low | > 103 |
| Pseudomonas syringae pv. syringae B728a | 0.48 | Psyr_1639 | | ribosomal large subunit pseudouridine synthase C | 0.53 | Psyr_2402 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II | low | > 86 |
| Pseudomonas fluorescens FW300-N2C3 | 0.48 | AO356_20125 | | 23S rRNA pseudouridylate synthase | 0.51 | AO356_25735 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase | low | > 104 |
| Pseudomonas sp. DMC3 | 0.48 | GFF4765 | | Ribosomal large subunit pseudouridine synthase C | 0.52 | GFF3048 | | Riboflavin biosynthesis protein RibBA | low | > 89 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.48 | Psyr_1639 | | ribosomal large subunit pseudouridine synthase C | 0.53 | Psyr_2402 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II | low | > 86 |
| Pseudomonas fluorescens SBW25-INTG | 0.47 | PFLU_RS23095 | | 23S rRNA pseudouridine(955/2504/2580) synthase RluC | 0.51 | PFLU_RS11510 | | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.47 | PFLU_RS23095 | | 23S rRNA pseudouridine(955/2504/2580) synthase RluC | 0.51 | PFLU_RS11510 | | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | low | > 109 |
| Pseudomonas lactucae CFBP13502 | 0.47 | GEMAOFIL_04440 | | Ribosomal large subunit pseudouridine synthase C | 0.51 | GEMAOFIL_02480 | | Riboflavin biosynthesis protein RibBA | low | > 93 |
| Pseudomonas simiae WCS417 | 0.47 | PS417_21480 | | 23S rRNA pseudouridylate synthase | 0.51 | PS417_25255 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.46 | AO353_01405 | | 23S rRNA pseudouridylate synthase | 0.49 | AO353_06705 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.46 | PfGW456L13_2097 | | Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) | 0.51 | PfGW456L13_1315 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25) | low | > 87 |
| Pseudomonas fluorescens FW300-N1B4 | 0.45 | Pf1N1B4_459 | | Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) | 0.50 | Pf1N1B4_2651 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25) | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.44 | QEN71_RS04500 | | RluA family pseudouridine synthase | 0.47 | QEN71_RS03290 | | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | low | > 153 |
| Burkholderia phytofirmans PsJN | 0.43 | BPHYT_RS14480 | | ribosomal large subunit pseudouridine synthase C | 0.47 | BPHYT_RS15390 | | 3,4-Dihydroxy-2-butanone 4-phosphate synthase | low | > 109 |
| Paraburkholderia graminis OAS925 | 0.43 | ABIE53_003058 | | 23S rRNA pseudouridine955/2504/2580 synthase | 0.47 | ABIE53_003246 | | 3,4-dihydroxy 2-butanone 4-phosphate synthase/GTP cyclohydrolase II | low | > 113 |
| Herbaspirillum seropedicae SmR1 | 0.43 | HSERO_RS09415 | | ribosomal large subunit pseudouridine synthase C | 0.50 | HSERO_RS17900 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase | low | > 78 |
| Acidovorax sp. GW101-3H11 | 0.43 | Ac3H11_1590 | | Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) | 0.48 | Ac3H11_3132 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25) | low | > 79 |
| Variovorax sp. SCN45 | 0.43 | GFF3847 | | LSU rRNA pseudouridine(955/2504/2580) synthase (EC 5.4.99.24) | 0.46 | GFF570 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25) | low | > 127 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.43 | H281DRAFT_04340 | | 23S rRNA pseudouridine955/2504/2580 synthase | 0.47 | H281DRAFT_04021 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase /GTP cyclohydrolase II | low | > 103 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.43 | Xcc-8004.2616.1 | | Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) | 0.53 | Xcc-8004.4389.1 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25) | — | — |
| Lysobacter sp. OAE881 | 0.42 | ABIE51_RS11800 | | RluA family pseudouridine synthase | 0.53 | ABIE51_RS04645 | | 3,4-dihydroxy-2-butanone-4-phosphate synthase | low | > 62 |
| Variovorax sp. OAS795 | 0.42 | ABID97_RS08250 | | RluA family pseudouridine synthase | 0.49 | ABID97_RS17945 | | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | low | > 91 |
| Rhodanobacter sp. FW510-T8 | 0.41 | OKGIIK_07405 | rluA | 23S rRNA pseudouridine(955/2504/2580) synthase | 0.55 | OKGIIK_11420 | ribB | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | low | > 52 |
| Rhodanobacter denitrificans FW104-10B01 | 0.41 | LRK54_RS17895 | | RluA family pseudouridine synthase | 0.55 | LRK54_RS04590 | | 3,4-dihydroxy-2-butanone-4-phosphate synthase | low | > 59 |
| Acinetobacter baumannii LAC-4 | 0.41 | RR41_RS16980 | | RluA family pseudouridine synthase | 0.54 | RR41_RS00450 | | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | 0.58 | 8 |
| Ralstonia solanacearum IBSBF1503 | 0.41 | RALBFv3_RS14375 | | RluA family pseudouridine synthase | 0.49 | RALBFv3_RS12815 | | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | low | > 76 |
| Dechlorosoma suillum PS | 0.41 | Dsui_2437 | | pseudouridine synthase, RluA family | 0.48 | Dsui_0715 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase | — | — |
| Ralstonia solanacearum UW163 | 0.41 | UW163_RS11840 | | RluA family pseudouridine synthase | 0.49 | UW163_RS00750 | | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.41 | RR42_RS14155 | | pseudouridine synthase | 0.48 | RR42_RS15565 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase | low | > 128 |
| Rhodanobacter denitrificans MT42 | 0.41 | LRK55_RS17750 | | RluA family pseudouridine synthase | 0.55 | LRK55_RS04365 | | 3,4-dihydroxy-2-butanone-4-phosphate synthase | — | — |
| Ralstonia solanacearum PSI07 | 0.41 | RPSI07_RS19085 | | RluA family pseudouridine synthase | 0.50 | RPSI07_RS20405 | | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | low | > 81 |
| Ralstonia solanacearum GMI1000 | 0.41 | RS_RS05155 | | RluA family pseudouridine synthase | 0.50 | RS_RS03590 | | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.41 | GFF121 | | Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70) | 0.48 | GFF5168 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25) | — | — |
| Methylophilus sp. DMC18 | 0.41 | GFF1177 | | Ribosomal large subunit pseudouridine synthase C | 0.48 | GFF872 | | Riboflavin biosynthesis protein RibBA | low | > 43 |
| Ralstonia sp. UNC404CL21Col | 0.41 | ABZR87_RS10090 | | RluA family pseudouridine synthase | 0.49 | ABZR87_RS08875 | | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | low | > 80 |
| Acinetobacter radioresistens SK82 | 0.40 | MPMX26_00317 | | Ribosomal large subunit pseudouridine synthase C | 0.54 | MPMX26_02970 | | Riboflavin biosynthesis protein RibBA | low | > 36 |
| Rhodanobacter sp000427505 FW510-R12 | 0.39 | LRK53_RS11465 | | RluA family pseudouridine synthase | 0.55 | LRK53_RS05410 | | 3,4-dihydroxy-2-butanone-4-phosphate synthase | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.38 | ABZR86_RS02725 | | RluA family pseudouridine synthase | 0.54 | ABZR86_RS10675 | | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | — | — |
| Castellaniella sp019104865 MT123 | 0.38 | ABCV34_RS08415 | | RluA family pseudouridine synthase | 0.49 | ABCV34_RS10135 | | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | — | — |
| Phaeobacter inhibens DSM 17395 | 0.30 | PGA1_c01950 | | ribosomal large subunit pseudouridine synthase C | 0.37 | PGA1_c08920 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase RibB | — | — |
| Agrobacterium fabrum C58 | 0.27 | Atu1471 | | ribosomal large subunit pseudouridine synthase C | 0.34 | Atu0753 | | 3,4-dihydroxy-2-butanone-4-phoshate synthase/GTP cyclohydrolase II | — | — |
| Magnetospirillum magneticum AMB-1 | 0.26 | AMB_RS15620 | | RluA family pseudouridine synthase | 0.44 | AMB_RS11835 | | 3,4-dihydroxy-2-butanone-4-phosphate synthase | — | — |
| Sinorhizobium meliloti 1021 | 0.26 | SMc01275 | | ribosomal large subunit pseudouridine synthase C protein | 0.34 | SMc00008 | | riboflavin biosynthesis protein RibA | low | > 103 |
| Rhizobium sp. OAE497 | 0.26 | ABIE40_RS09915 | | RluA family pseudouridine synthase | 0.34 | ABIE40_RS03975 | | 3,4-dihydroxy-2-butanone-4-phosphate synthase | low | > 107 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.25 | A4249_RS07865 | | RluA family pseudouridine synthase | 0.41 | A4249_RS06020 | | 3,4-dihydroxy-2-butanone-4-phosphate synthase | — | — |
| Caulobacter crescentus NA1000 | 0.25 | CCNA_02059 | | ribosomal large subunit pseudouridine synthase C | 0.33 | CCNA_00931 | | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase | low | > 66 |
| Caulobacter crescentus NA1000 Δfur | 0.25 | CCNA_02059 | | ribosomal large subunit pseudouridine synthase C | 0.33 | CCNA_00931 | | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase | low | > 67 |
| Rhodospirillum rubrum S1H | 0.25 | Rru_A2659 | | Pseudouridine synthase, RluD (NCBI) | 0.41 | Rru_A1823 | | 3,4-Dihydroxy-2-butanone 4-phosphate synthase (NCBI) | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.24 | Ga0059261_1033 | | pseudouridine synthase, RluA family | 0.43 | Ga0059261_2334 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase | — | — |
| Dinoroseobacter shibae DFL-12 | 0.24 | Dshi_0315 | | pseudouridine synthase, RluA family (RefSeq) | 0.42 | Dshi_2251 | | 3,4-dihydroxy-2-butanone 4-phosphate synthase (RefSeq) | — | — |
| Fusobacterium nucleatum SB010 | 0.23 | HUW76_04985 | | RluA family pseudouridine synthase | 0.38 | HUW76_09295 | | bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II | — | — |
| Azospirillum sp. SherDot2 | 0.23 | MPMX19_01718 | | Ribosomal large subunit pseudouridine synthase C | 0.44 | MPMX19_00734 | | Riboflavin biosynthesis protein RibBA | low | > 112 |
| Xanthobacter sp. DMC5 | 0.22 | GFF1347 | | Ribosomal large subunit pseudouridine synthase C | 0.35 | GFF964 | | Riboflavin biosynthesis protein RibBA | — | — |
| Azospirillum brasilense Sp245 | 0.21 | AZOBR_RS06905 | | pseudouridine synthase | 0.44 | AZOBR_RS10035 | | 3 4-dihydroxy-2-butanone 4-phosphate synthase | — | — |
Not shown: 29 genomes with orthologs for CSW01_10130 only; 18 genomes with orthologs for CSW01_11550 only