Conservation of cofitness between CSW01_02320 and CSW01_10025 in Vibrio cholerae E7946 ATCC 55056

85 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02320 Co2+/Mg2+ efflux protein ApaG 1.0 CSW01_10025 pyruvate kinase 0.53 20
Shewanella loihica PV-4 0.56 Shew_0878 apaG ApaG (RefSeq) 0.62 Shew_2050 pyruvate kinase (RefSeq) — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.56 GFF191 ApaG protein 0.67 GFF1633 Pyruvate kinase (EC 2.7.1.40) low > 78
Klebsiella michiganensis M5al 0.55 BWI76_RS04515 Co2+/Mg2+ efflux protein ApaG 0.67 BWI76_RS18115 pyruvate kinase low > 92
Pectobacterium carotovorum WPP14 0.55 HER17_RS02955 Co2+/Mg2+ efflux protein ApaG 0.68 HER17_RS11790 pyruvate kinase low > 75
Dickeya dadantii 3937 0.54 DDA3937_RS18270 Co2+/Mg2+ efflux protein ApaG 0.67 DDA3937_RS10125 pyruvate kinase low > 74
Klebsiella pneumoniae MKP103 0.54 KDGMDA_12740 Co2+/Mg2+ efflux protein ApaG 0.67 KDGMDA_25380 pyruvate kinase low > 95
Shewanella sp. ANA-3 0.54 Shewana3_3210 apaG ApaG (RefSeq) 0.62 Shewana3_2153 pyruvate kinase (RefSeq) low > 73
Dickeya dianthicola 67-19 0.54 HGI48_RS18205 Co2+/Mg2+ efflux protein ApaG 0.67 HGI48_RS10155 pyruvate kinase low > 71
Dickeya dianthicola ME23 0.54 DZA65_RS19345 Co2+/Mg2+ efflux protein ApaG 0.67 DZA65_RS10570 pyruvate kinase low > 75
Escherichia coli ECRC102 0.54 NIAGMN_08690 apaG Co2+/Mg2+ efflux protein ApaG 0.67 NIAGMN_01740 pyk pyruvate kinase low > 80
Escherichia coli ECRC62 0.54 BNILDI_08420 apaG Co2+/Mg2+ efflux protein ApaG 0.67 BNILDI_15630 pyk pyruvate kinase low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.54 OHPLBJKB_03606 Protein ApaG 0.67 OHPLBJKB_01874 Pyruvate kinase II low > 74
Escherichia coli BW25113 0.54 b0050 apaG hypothetical protein (NCBI) 0.67 b1854 pykA pyruvate kinase (NCBI) low > 76
Escherichia coli ECRC98 0.54 JDDGAC_14435 apaG Co2+/Mg2+ efflux protein ApaG 0.67 JDDGAC_00895 pyk pyruvate kinase low > 87
Escherichia coli ECOR38 0.54 HEPCGN_08830 apaG Co2+/Mg2+ efflux protein ApaG 0.68 HEPCGN_04725 pyk pyruvate kinase low > 88
Escherichia coli ECRC100 0.54 OKFHMN_10840 apaG Co2+/Mg2+ efflux protein ApaG 0.67 OKFHMN_26320 pyk pyruvate kinase low > 79
Escherichia coli ECOR27 0.54 NOLOHH_03185 apaG Co2+/Mg2+ efflux protein ApaG 0.67 NOLOHH_16835 pyk pyruvate kinase low > 76
Pantoea agglomerans CFBP13505 P0401 0.54 PagCFBP13505_RS12905 Co2+/Mg2+ efflux protein ApaG 0.68 PagCFBP13505_RS02365 pyruvate kinase low > 74
Escherichia coli ECRC101 0.54 MCAODC_01355 apaG Co2+/Mg2+ efflux protein ApaG 0.67 MCAODC_19085 pyk pyruvate kinase low > 88
Escherichia fergusonii Becca 0.54 EFB2_03993 Protein ApaG 0.68 EFB2_02088 Pyruvate kinase II low > 86
Escherichia coli Nissle 1917 0.54 ECOLIN_RS00280 Co2+/Mg2+ efflux protein ApaG 0.68 ECOLIN_RS10330 pyruvate kinase low > 55
Pantoea sp. MT58 0.54 IAI47_16090 Co2+/Mg2+ efflux protein ApaG 0.68 IAI47_08485 pyruvate kinase low > 76
Escherichia coli ECRC99 0.54 KEDOAH_17315 apaG Co2+/Mg2+ efflux protein ApaG 0.67 KEDOAH_01785 pyk pyruvate kinase — —
Escherichia coli BL21 0.54 ECD_00054 protein associated with Co2+ and Mg2+ efflux 0.67 ECD_01825 pyruvate kinase II 0.33 34
Rahnella sp. WP5 0.53 EX31_RS03785 Co2+/Mg2+ efflux protein ApaG 0.67 EX31_RS10640 pyruvate kinase low > 89
Shewanella oneidensis MR-1 0.53 SO3640 apaG apaG protein (NCBI ptt file) 0.62 SO2491 pykA pyruvate kinase II (NCBI ptt file) low > 76
Serratia liquefaciens MT49 0.53 IAI46_03240 Co2+/Mg2+ efflux protein ApaG 0.68 IAI46_14585 pyruvate kinase low > 86
Erwinia tracheiphila HP pepo 2.2 0.52 IJEDHG_06160 apaG Co2+/Mg2+ efflux protein ApaG 0.67 IJEDHG_22180 pyk pyruvate kinase low > 61
Erwinia tracheiphila SCR3 0.52 LU632_RS02735 apaG Co2+/Mg2+ efflux protein ApaG 0.67 LU632_RS13370 pyk pyruvate kinase low > 74
Shewanella amazonensis SB2B 0.52 Sama_2820 apaG ApaG (RefSeq) 0.61 Sama_1814 pyruvate kinase (RefSeq) low > 62
Alteromonas macleodii MIT1002 0.51 MIT1002_00780 CO2+/MG2+ efflux protein ApaG 0.60 MIT1002_02409 Pyruvate kinase II — —
Enterobacter sp. TBS_079 0.51 MPMX20_00746 Protein ApaG 0.67 MPMX20_02759 Pyruvate kinase II low > 85
Pseudomonas putida KT2440 0.51 PP_0400 CO2+/MG2+ efflux protein 0.56 PP_1362 pyruvate kinase II low > 96
Erwinia amylovora T8 0.51 OLJFJH_01375 Co2+/Mg2+ efflux protein ApaG 0.67 OLJFJH_12895 pyruvate kinase low > 58
Pseudomonas sp. BP01 0.51 JOY50_RS18135 apaG Co2+/Mg2+ efflux protein ApaG 0.55 JOY50_RS14320 pyk pyruvate kinase low > 84
Pseudomonas fluorescens FW300-N2E2 0.51 Pf6N2E2_4804 ApaG protein 0.54 Pf6N2E2_5494 Pyruvate kinase (EC 2.7.1.40) low > 103
Pseudomonas fluorescens FW300-N2C3 0.50 AO356_14330 magnesium transporter ApaG 0.54 AO356_17830 pyruvate kinase low > 104
Enterobacter asburiae PDN3 0.50 EX28DRAFT_3644 Uncharacterized protein affecting Mg2+/Co2+ transport 0.67 EX28DRAFT_0702 pyruvate kinase 0.58 59
Pseudomonas sp. RS175 0.50 PFR28_04065 Protein ApaG 0.54 PFR28_03455 Pyruvate kinase II low > 88
Pseudomonas sp. SVBP6 0.49 COO64_RS22515 apaG Co2+/Mg2+ efflux protein ApaG 0.57 COO64_RS12190 pyk pyruvate kinase 0.56 23
Pseudomonas stutzeri RCH2 0.49 Psest_3669 Uncharacterized protein affecting Mg2+/Co2+ transport 0.53 Psest_3190 pyruvate kinase low > 67
Pseudomonas sp. DMC3 0.49 GFF38 Protein ApaG 0.54 GFF5030 Pyruvate kinase II low > 89
Pseudomonas syringae pv. syringae B728a 0.49 Psyr_4628 Protein of unknown function DUF525 0.54 Psyr_4029 pyruvate kinase low > 86
Pseudomonas sp. S08-1 0.49 OH686_15035 ApaG protein 0.54 OH686_18800 pyruvate kinase low > 80
Pseudomonas fluorescens GW456-L13 0.49 PfGW456L13_1199 ApaG protein 0.54 PfGW456L13_1813 Pyruvate kinase (EC 2.7.1.40) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.49 Psyr_4628 Protein of unknown function DUF525 0.54 Psyr_4029 pyruvate kinase low > 86
Pseudomonas segetis P6 0.48 MPMX49_00878 Protein ApaG 0.56 MPMX49_03725 Pyruvate kinase II low > 75
Pseudomonas fluorescens FW300-N1B4 0.48 Pf1N1B4_2527 ApaG protein 0.55 Pf1N1B4_678 Pyruvate kinase (EC 2.7.1.40) low > 87
Dyella japonica UNC79MFTsu3.2 0.48 ABZR86_RS11275 Co2+/Mg2+ efflux protein ApaG 0.41 ABZR86_RS18630 pyruvate kinase low > 74
Kangiella aquimarina DSM 16071 0.48 B158DRAFT_0584 Uncharacterized protein affecting Mg2+/Co2+ transport 0.57 B158DRAFT_1404 pyruvate kinase low > 40
Pseudomonas fluorescens FW300-N2E3 0.48 AO353_07320 magnesium transporter ApaG 0.54 AO353_03775 pyruvate kinase low > 101
Rhodanobacter denitrificans FW104-10B01 0.48 LRK54_RS12300 Co2+/Mg2+ efflux protein ApaG 0.45 LRK54_RS05775 pyruvate kinase low > 59
Rhodanobacter denitrificans MT42 0.48 LRK55_RS12035 Co2+/Mg2+ efflux protein ApaG 0.45 LRK55_RS05530 pyruvate kinase low > 63
Pseudomonas aeruginosa PA14 0.48 IKLFDK_22455 Co2+/Mg2+ efflux protein ApaG 0.54 IKLFDK_02460 pyruvate kinase low > 100
Rhodanobacter sp. FW510-T8 0.48 OKGIIK_11630 apaG Co2+/Mg2+ efflux protein ApaG 0.45 OKGIIK_01070 pyk pyruvate kinase low > 53
Pseudomonas lactucae CFBP13502 0.47 GEMAOFIL_05283 Protein ApaG 0.54 GEMAOFIL_04678 Pyruvate kinase II low > 93
Rhodanobacter sp000427505 FW510-R12 0.47 LRK53_RS16195 Co2+/Mg2+ efflux protein ApaG 0.46 LRK53_RS17135 pyruvate kinase low > 59
Pseudomonas simiae WCS417 0.46 PS417_25815 magnesium transporter ApaG 0.54 PS417_22620 pyruvate kinase low > 88
Pseudomonas fluorescens SBW25-INTG 0.46 PFLU_RS27470 Co2+/Mg2+ efflux protein ApaG 0.54 PFLU_RS24255 pyruvate kinase low > 109
Pseudomonas fluorescens SBW25 0.46 PFLU_RS27470 Co2+/Mg2+ efflux protein ApaG 0.54 PFLU_RS24255 pyruvate kinase low > 109
Dechlorosoma suillum PS 0.46 Dsui_0222 uncharacterized protein affecting Mg2+/Co2+ transport 0.49 Dsui_0052 pyruvate kinase low > 51
Magnetospirillum magneticum AMB-1 0.44 AMB_RS21360 Co2+/Mg2+ efflux protein ApaG 0.31 AMB_RS16010 pyruvate kinase — —
Herbaspirillum seropedicae SmR1 0.44 HSERO_RS19420 cobalt transporter 0.46 HSERO_RS03350 hypothetical protein — —
Sinorhizobium meliloti 1021 0.43 SMc02135 ApaG protein 0.28 SMc04005 pyruvate kinase low > 103
Rhizobium sp. OAE497 0.43 ABIE40_RS02335 Co2+/Mg2+ efflux protein ApaG 0.26 ABIE40_RS16145 pyruvate kinase — —
Sphingomonas koreensis DSMZ 15582 0.43 Ga0059261_3195 Uncharacterized protein affecting Mg2+/Co2+ transport 0.29 Ga0059261_0685 pyruvate kinase low > 68
Xanthomonas campestris pv. campestris strain 8004 0.43 Xcc-8004.4273.1 ApaG protein 0.45 Xcc-8004.1243.1 Pyruvate kinase (EC 2.7.1.40) low > 74
Xanthobacter sp. DMC5 0.42 GFF4633 Protein ApaG 0.30 GFF1958 Pyruvate kinase — —
Cupriavidus basilensis FW507-4G11 0.42 RR42_RS18280 magnesium transporter ApaG 0.44 RR42_RS03210 pyruvate kinase 0.32 29
Ralstonia solanacearum PSI07 0.41 RPSI07_RS10770 Co2+/Mg2+ efflux protein ApaG 0.45 RPSI07_RS21150 pyruvate kinase low > 81
Ralstonia solanacearum GMI1000 0.41 RS_RS14415 Co2+/Mg2+ efflux protein ApaG 0.45 RS_RS02865 pyruvate kinase low > 80
Ralstonia sp. UNC404CL21Col 0.41 ABZR87_RS02125 Co2+/Mg2+ efflux protein ApaG 0.45 ABZR87_RS08070 pyruvate kinase low > 80
Paraburkholderia sabiae LMG 24235 0.41 QEN71_RS27535 Co2+/Mg2+ efflux protein ApaG 0.46 QEN71_RS02430 pyruvate kinase low > 153
Ralstonia solanacearum IBSBF1503 0.41 RALBFv3_RS06470 Co2+/Mg2+ efflux protein ApaG 0.45 RALBFv3_RS12180 pyruvate kinase low > 76
Ralstonia solanacearum UW163 0.41 UW163_RS07155 Co2+/Mg2+ efflux protein ApaG 0.45 UW163_RS01430 pyruvate kinase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.41 GFF3095 ApaG protein 0.46 GFF2780 Pyruvate kinase (EC 2.7.1.40) low > 90
Bosea sp. OAE506 0.40 ABIE41_RS04315 Co2+/Mg2+ efflux protein ApaG 0.28 ABIE41_RS06285 pyruvate kinase low > 77
Burkholderia phytofirmans PsJN 0.39 BPHYT_RS17375 magnesium transporter ApaG 0.47 BPHYT_RS16265 hypothetical protein low > 109
Variovorax sp. OAS795 0.39 ABID97_RS04900 Co2+/Mg2+ efflux protein ApaG 0.46 ABID97_RS01755 pyruvate kinase low > 91
Paraburkholderia bryophila 376MFSha3.1 0.39 H281DRAFT_05718 ApaG protein 0.47 H281DRAFT_04189 pyruvate kinase low > 103
Mucilaginibacter yixingensis YX-36 DSM 26809 0.39 ABZR88_RS22335 Co2+/Mg2+ efflux protein ApaG 0.33 ABZR88_RS01590 pyruvate kinase — —
Paraburkholderia graminis OAS925 0.38 ABIE53_003637 ApaG protein 0.47 ABIE53_003427 pyruvate kinase low > 113
Lysobacter sp. OAE881 0.38 ABIE51_RS05380 Co2+/Mg2+ efflux protein ApaG 0.44 ABIE51_RS17040 pyruvate kinase 0.24 47
Variovorax sp. SCN45 0.37 GFF6247 ApaG protein 0.47 GFF5504 Pyruvate kinase (EC 2.7.1.40) low > 127
Acidovorax sp. GW101-3H11 0.35 Ac3H11_756 ApaG protein 0.47 Ac3H11_654 Pyruvate kinase (EC 2.7.1.40) low > 79

Not shown: 12 genomes with orthologs for CSW01_02320 only; 3 genomes with orthologs for CSW01_10025 only