Conservation of cofitness between CSW01_00335 and CSW01_00205 in Vibrio cholerae E7946 ATCC 55056

86 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_00335 phosphomethylpyrimidine synthase 1.0 CSW01_00205 hemolysin III family protein 0.49 11
Pectobacterium carotovorum WPP14 0.76 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.64 HER17_RS17935 hemolysin III family protein low > 75
Rahnella sp. WP5 0.76 EX31_RS16815 phosphomethylpyrimidine synthase ThiC 0.69 EX31_RS21610 hemolysin III family protein low > 89
Klebsiella pneumoniae MKP103 0.75 KDGMDA_10040 phosphomethylpyrimidine synthase ThiC 0.76 KDGMDA_04325 hemolysin III family protein 0.21 43
Dickeya dianthicola ME23 0.75 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.67 DZA65_RS03455 hemolysin III family protein low > 75
Dickeya dadantii 3937 0.75 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.74 DDA3937_RS03270 hemolysin III family protein low > 74
Erwinia amylovora T8 0.75 OLJFJH_06740 phosphomethylpyrimidine synthase ThiC 0.64 OLJFJH_08800 hemolysin III family protein low > 58
Pantoea sp. MT58 0.75 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.67 IAI47_03795 hemolysin III family protein low > 76
Escherichia coli ECOR27 0.75 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 0.73 NOLOHH_11465 yqfA hemolysin III family protein low > 76
Serratia liquefaciens MT49 0.75 IAI46_01320 phosphomethylpyrimidine synthase ThiC 0.72 IAI46_20775 hemolysin III family protein low > 87
Enterobacter sp. TBS_079 0.75 MPMX20_00217 Phosphomethylpyrimidine synthase 0.76 MPMX20_03758 hypothetical protein low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.75 GFF4198 Thiamin biosynthesis protein ThiC 0.74 GFF2997 COG1272: Predicted membrane protein hemolysin III homolog low > 78
Escherichia coli BW25113 0.74 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.73 b2899 yqfA predicted oxidoreductase, inner membrane subunit (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.74 OHPLBJKB_04056 Phosphomethylpyrimidine synthase 0.73 OHPLBJKB_00816 hypothetical protein low > 74
Pantoea agglomerans CFBP13505 P0401 0.74 PagCFBP13505_RS22620 phosphomethylpyrimidine synthase ThiC 0.69 PagCFBP13505_RS15905 hemolysin III family protein low > 74
Escherichia coli ECRC62 0.74 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.73 BNILDI_10000 yqfA hemolysin III family protein low > 75
Klebsiella michiganensis M5al 0.74 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.76 BWI76_RS23840 hemolysin III family protein low > 92
Escherichia coli Nissle 1917 0.74 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.73 ECOLIN_RS16150 hemolysin III family protein low > 55
Escherichia coli ECRC99 0.74 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC 0.73 KEDOAH_08595 yqfA hemolysin III family protein — —
Escherichia coli ECRC98 0.74 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC 0.73 JDDGAC_23185 yqfA hemolysin III family protein low > 87
Dickeya dianthicola 67-19 0.74 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.68 HGI48_RS03410 hemolysin III family protein low > 71
Escherichia coli ECRC102 0.74 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC 0.73 NIAGMN_17310 yqfA hemolysin III family protein low > 80
Escherichia coli ECRC100 0.74 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.73 OKFHMN_19545 yqfA hemolysin III family protein low > 79
Escherichia coli ECRC101 0.74 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.73 MCAODC_10065 yqfA hemolysin III family protein low > 87
Escherichia coli BL21 0.74 ECD_03871 phosphomethylpyrimidine synthase 0.73 ECD_02731 hemolysin III family HylIII inner membrane protein low > 61
Escherichia coli ECOR38 0.74 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.73 HEPCGN_18835 yqfA hemolysin III family protein low > 88
Escherichia fergusonii Becca 0.74 EFB2_04617 Phosphomethylpyrimidine synthase 0.73 EFB2_01002 hypothetical protein low > 86
Enterobacter asburiae PDN3 0.74 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.76 EX28DRAFT_2950 channel protein, hemolysin III family low > 76
Shewanella loihica PV-4 0.74 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.48 Shew_2098 hemolysin III family channel protein (RefSeq) low > 60
Alteromonas macleodii MIT1002 0.74 MIT1002_00097 Phosphomethylpyrimidine synthase 0.52 MIT1002_00886 hemolysin low > 70
Shewanella amazonensis SB2B 0.72 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.44 Sama_1862 hemolysin III family channel protein (RefSeq) low > 62
Shewanella oneidensis MR-1 0.71 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.48 SO2447 channel protein, hemolysin III family subfamily (NCBI ptt file) low > 76
Pseudomonas aeruginosa MRSN321 0.71 DY961_RS10660 thiC;go_function=iron-sulfur phosphomethylpyrimidine synthase ThiC 0.33 DY961_RS09940 hemolysin III family protein low > 100
Pseudomonas aeruginosa PUPa3 0.71 DQ20_RS51400 thiC;go_function=iron-sulfur phosphomethylpyrimidine synthase ThiC 0.33 DQ20_RS52110 hemolysin III family protein low > 101
Pseudomonas aeruginosa PA14 0.71 IKLFDK_28675 phosphomethylpyrimidine synthase ThiC 0.33 IKLFDK_29400 hemolysin III low > 98
Shewanella sp. ANA-3 0.71 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.46 Shewana3_1934 hemolysin III family channel protein (RefSeq) low > 73
Pseudomonas sp. S08-1 0.70 OH686_15885 phosphomethylpyrimidine synthase 0.34 OH686_06045 Predicted membrane protein, hemolysin III-related low > 80
Pseudomonas putida KT2440 0.70 PP_4922 Phosphomethylpyrimidine synthase 0.37 PP_4986 Channel protein, hemolysin III family low > 96
Pseudomonas sp. DMC3 0.70 GFF3183 Phosphomethylpyrimidine synthase 0.34 GFF181 hypothetical protein low > 89
Marinobacter adhaerens HP15 0.70 HP15_453 thiamine biosynthesis protein thiC 0.44 HP15_2974 channel protein, hemolysin III family low > 73
Pseudomonas sp. BP01 0.69 JOY50_RS10065 thiC phosphomethylpyrimidine synthase ThiC 0.35 JOY50_RS09760 hemolysin III family protein low > 84
Pseudomonas sp. SVBP6 0.69 COO64_RS17755 thiC phosphomethylpyrimidine synthase ThiC 0.35 COO64_RS13640 hemolysin III family protein low > 93
Pseudomonas stutzeri RCH2 0.69 Psest_0477 thiamine biosynthesis protein ThiC 0.32 Psest_3779 channel protein, hemolysin III family low > 67
Pseudomonas fluorescens FW300-N2C3 0.69 AO356_08810 thiamine biosynthesis protein ThiC 0.35 AO356_13560 hemolysin III 0.22 69
Pseudomonas sp. RS175 0.69 PFR28_05091 Phosphomethylpyrimidine synthase 0.35 PFR28_04213 hypothetical protein low > 88
Pseudomonas fluorescens GW456-L13 0.69 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.34 PfGW456L13_1038 COG1272: Predicted membrane protein hemolysin III homolog low > 87
Pseudomonas fluorescens FW300-N2E2 0.69 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.35 Pf6N2E2_4629 COG1272: Predicted membrane protein hemolysin III homolog low > 103
Pseudomonas fluorescens FW300-N1B4 0.69 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.34 Pf1N1B4_2371 COG1272: Predicted membrane protein hemolysin III homolog low > 87
Pseudomonas lactucae CFBP13502 0.69 GEMAOFIL_00708 Phosphomethylpyrimidine synthase 0.35 GEMAOFIL_05445 hypothetical protein low > 96
Pseudomonas simiae WCS417 0.69 PS417_02355 thiamine biosynthesis protein ThiC 0.34 PS417_26570 hemolysin III low > 88
Pseudomonas syringae pv. syringae B728a 0.69 Psyr_0544 hydroxymethylpyrimidine synthase 0.35 Psyr_0452 HylII low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.69 Psyr_0544 hydroxymethylpyrimidine synthase 0.35 Psyr_0452 HylII low > 86
Pseudomonas fluorescens FW300-N2E3 0.69 AO353_13010 thiamine biosynthesis protein ThiC 0.33 AO353_08075 hemolysin III low > 101
Pseudomonas fluorescens SBW25-INTG 0.69 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.34 PFLU_RS28225 hemolysin III family protein low > 109
Pseudomonas fluorescens SBW25 0.69 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.34 PFLU_RS28225 hemolysin III family protein low > 109
Acinetobacter radioresistens SK82 0.68 MPMX26_00180 Phosphomethylpyrimidine synthase 0.45 MPMX26_00606 hypothetical protein low > 36
Acinetobacter baumannii LAC-4 0.68 RR41_RS17715 phosphomethylpyrimidine synthase ThiC 0.42 RR41_RS03190 hemolysin III family protein low > 55
Cellulophaga baltica 18 0.68 M666_RS10600 phosphomethylpyrimidine synthase ThiC 0.36 M666_RS10220 hemolysin III family protein low > 67
Pedobacter sp. GW460-11-11-14-LB5 0.68 CA265_RS20165 phosphomethylpyrimidine synthase ThiC 0.21 CA265_RS22915 hypothetical protein low > 88
Lysobacter sp. OAE881 0.68 ABIE51_RS17515 phosphomethylpyrimidine synthase ThiC 0.39 ABIE51_RS16230 hemolysin III family protein low > 62
Paraburkholderia bryophila 376MFSha3.1 0.68 H281DRAFT_00395 hydroxymethylpyrimidine synthase 0.37 H281DRAFT_04221 hemolysin III low > 103
Paraburkholderia graminis OAS925 0.68 ABIE53_002857 phosphomethylpyrimidine synthase 0.38 ABIE53_003461 hemolysin III low > 113
Dyella japonica UNC79MFTsu3.2 0.67 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC 0.44 ABZR86_RS18160 hemolysin III family protein low > 74
Burkholderia phytofirmans PsJN 0.67 BPHYT_RS13220 phosphomethylpyrimidine synthase 0.38 BPHYT_RS16440 hemolysin D low > 109
Paraburkholderia sabiae LMG 24235 0.67 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC 0.38 QEN71_RS02270 hemolysin III family protein low > 153
Rhodanobacter sp. FW510-T8 0.67 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC 0.45 OKGIIK_00475 yqfA putative membrane channel-forming protein YqfA, hemolysin III family low > 53
Xanthomonas campestris pv. campestris strain 8004 0.66 Xcc-8004.1066.1 hypothetical protein 0.40 Xcc-8004.1589.1 COG1272: Predicted membrane protein hemolysin III homolog low > 74
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC 0.32 ABZR87_RS02015 hemolysin III family protein low > 80
Kangiella aquimarina DSM 16071 0.65 B158DRAFT_0295 hydroxymethylpyrimidine synthase 0.47 B158DRAFT_1582 channel protein, hemolysin III family low > 40
Variovorax sp. SCN45 0.64 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.32 GFF5671 FIG01964566: Predicted membrane protein, hemolysin III homolog low > 127
Variovorax sp. OAS795 0.63 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC 0.36 ABID97_RS07605 hemolysin III family protein low > 91
Agrobacterium fabrum C58 0.61 Atu2569 thiamine biosynthesis protein 0.34 Atu0906 Hemolysin III low > 89
Sinorhizobium meliloti 1021 0.61 SM_b20615 thiamine biosynthesis protein ThiC 0.34 SMc00455 hypothetical protein low > 103
Dinoroseobacter shibae DFL-12 0.61 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) 0.24 Dshi_2910 Hly-III family protein (RefSeq) — —
Brevundimonas sp. GW460-12-10-14-LB2 0.61 A4249_RS15715 phosphomethylpyrimidine synthase ThiC 0.24 A4249_RS14635 hemolysin III family protein low > 48
Azospirillum brasilense Sp245 0.61 AZOBR_RS07940 phosphomethylpyrimidine synthase 0.31 AZOBR_RS18955 DNA-binding protein low > 97
Acidovorax sp. GW101-3H11 0.61 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.38 Ac3H11_4296 COG1272: Predicted membrane protein hemolysin III homolog low > 79
Azospirillum sp. SherDot2 0.59 MPMX19_00336 Phosphomethylpyrimidine synthase 0.29 MPMX19_02364 hypothetical protein low > 112
Rhodopseudomonas palustris CGA009 0.59 TX73_018540 phosphomethylpyrimidine synthase ThiC 0.30 TX73_008140 hemolysin III family protein low > 86
Rhodanobacter sp000427505 FW510-R12 0.58 LRK53_RS03795 phosphomethylpyrimidine synthase ThiC 0.45 LRK53_RS17430 hemolysin III family protein low > 59
Rhodospirillum rubrum S1H 0.56 Rru_A2008 Thiamine biosynthesis protein ThiC (NCBI) 0.30 Rru_A0661 Hly-III related proteins (NCBI) low > 58
Phocaeicola vulgatus CL09T03C04 0.55 HMPREF1058_RS03280 phosphomethylpyrimidine synthase ThiC 0.24 HMPREF1058_RS00565 hemolysin III family protein low > 67
Phocaeicola dorei CL03T12C01 0.55 ABI39_RS17760 phosphomethylpyrimidine synthase ThiC 0.24 ABI39_RS08185 hemolysin III family protein low > 72
Parabacteroides merdae CL09T00C40 0.55 HMPREF1078_RS03485 phosphomethylpyrimidine synthase ThiC 0.34 HMPREF1078_RS01905 hemolysin III family protein 0.76 11
Bacteroides thetaiotaomicron VPI-5482 0.55 BT0650 thiamine biosynthesis protein ThiC (NCBI ptt file) 0.27 BT1983 hemolysin III (NCBI ptt file) low > 81
Bacteroides ovatus ATCC 8483 0.55 BACOVA_02358 thiamine biosynthesis protein ThiC 0.28 BACOVA_00687 hypothetical protein low > 96
Bacteroides stercoris CC31F 0.55 HMPREF1181_RS14685 phosphomethylpyrimidine synthase ThiC 0.24 HMPREF1181_RS16820 hemolysin III family protein low > 56

Not shown: 25 genomes with orthologs for CSW01_00335 only; 7 genomes with orthologs for CSW01_00205 only