Conservation of cofitness between BWI76_RS00855 and BWI76_RS04680 in Klebsiella michiganensis M5al

70 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS00855 argininosuccinate lyase 1.0 BWI76_RS04680 2-isopropylmalate synthase 0.91 14
Escherichia coli ECOR38 0.96 HEPCGN_12220 argH argininosuccinate lyase 0.95 HEPCGN_08695 2-isopropylmalate synthase 0.99 1
Escherichia coli BL21 0.96 ECD_03845 argininosuccinate lyase 0.95 ECD_00076 2-isopropylmalate synthase 0.87 16
Escherichia coli BW25113 0.96 b3960 argH argininosuccinate lyase (NCBI) 0.95 b0074 leuA 2-isopropylmalate synthase (NCBI) 0.91 32
Escherichia coli HS(pFamp)R (ATCC 700891) 0.96 OHPLBJKB_04090 Argininosuccinate lyase 0.95 OHPLBJKB_03583 2-isopropylmalate synthase low > 73
Escherichia coli ECRC100 0.96 OKFHMN_13575 argH argininosuccinate lyase 0.94 OKFHMN_10715 2-isopropylmalate synthase 0.95 23
Escherichia coli ECRC98 0.96 JDDGAC_17200 argH argininosuccinate lyase 0.94 JDDGAC_14310 2-isopropylmalate synthase 0.89 29
Escherichia coli Nissle 1917 0.96 ECOLIN_RS22855 argininosuccinate lyase 0.95 ECOLIN_RS00400 2-isopropylmalate synthase 0.98 4
Escherichia coli ECRC99 0.96 KEDOAH_14585 argH argininosuccinate lyase 0.94 KEDOAH_17440 2-isopropylmalate synthase — —
Escherichia coli ECRC101 0.96 MCAODC_04075 argH argininosuccinate lyase 0.94 MCAODC_01230 2-isopropylmalate synthase 0.90 18
Escherichia fergusonii Becca 0.96 EFB2_04654 Argininosuccinate lyase 0.94 EFB2_03971 2-isopropylmalate synthase low > 86
Escherichia coli ECOR27 0.96 NOLOHH_05720 argH argininosuccinate lyase 0.95 NOLOHH_03060 2-isopropylmalate synthase 0.92 33
Escherichia coli ECRC62 0.96 BNILDI_05805 argH argininosuccinate lyase 0.95 BNILDI_08550 2-isopropylmalate synthase 0.96 32
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4422 argininosuccinate lyase 0.96 EX28DRAFT_3670 2-isopropylmalate synthase (EC 2.3.3.13) 0.71 46
Escherichia coli ECRC102 0.95 NIAGMN_11325 argH argininosuccinate lyase 0.94 NIAGMN_08565 2-isopropylmalate synthase — —
Enterobacter sp. TBS_079 0.94 MPMX20_04520 Argininosuccinate lyase 0.95 MPMX20_00769 2-isopropylmalate synthase 0.84 52
Pantoea sp. MT58 0.90 IAI47_00920 argininosuccinate lyase 0.83 IAI47_16000 2-isopropylmalate synthase 0.98 12
Serratia liquefaciens MT49 0.90 IAI46_24500 argininosuccinate lyase 0.85 IAI46_03355 2-isopropylmalate synthase 0.65 54
Rahnella sp. WP5 0.90 EX31_RS14180 argininosuccinate lyase 0.82 EX31_RS03680 2-isopropylmalate synthase 0.96 35
Erwinia tracheiphila SCR3 0.87 LU632_RS19600 argH argininosuccinate lyase 0.85 LU632_RS02880 leuA 2-isopropylmalate synthase 0.82 17
Pectobacterium carotovorum WPP14 0.87 HER17_RS20620 argininosuccinate lyase 0.87 HER17_RS03085 2-isopropylmalate synthase 0.74 42
Dickeya dadantii 3937 0.87 DDA3937_RS20340 argininosuccinate lyase 0.86 DDA3937_RS18115 2-isopropylmalate synthase 0.63 66
Dickeya dianthicola 67-19 0.85 HGI48_RS00885 argininosuccinate lyase 0.86 HGI48_RS18055 2-isopropylmalate synthase 0.91 5
Dickeya dianthicola ME23 0.85 DZA65_RS00945 argininosuccinate lyase 0.86 DZA65_RS19200 2-isopropylmalate synthase 0.60 60
Vibrio cholerae E7946 ATCC 55056 0.74 CSW01_13360 argininosuccinate lyase 0.68 CSW01_12595 2-isopropylmalate synthase low > 62
Shewanella amazonensis SB2B 0.65 Sama_0260 argininosuccinate lyase (RefSeq) 0.66 Sama_0335 2-isopropylmalate synthase (RefSeq) 0.91 43
Shewanella sp. ANA-3 0.63 Shewana3_3901 argininosuccinate lyase (RefSeq) 0.66 Shewana3_3761 2-isopropylmalate synthase (RefSeq) 0.87 23
Shewanella oneidensis MR-1 0.63 SO0279 argH argininosuccinate lyase (NCBI ptt file) 0.66 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) 0.95 14
Shewanella loihica PV-4 0.63 Shew_0206 argininosuccinate lyase (RefSeq) 0.66 Shew_3472 2-isopropylmalate synthase (RefSeq) 0.99 3
Alteromonas macleodii MIT1002 0.57 MIT1002_00467 Argininosuccinate lyase 0.62 MIT1002_00949 2-isopropylmalate synthase 0.95 39
Marinobacter adhaerens HP15 0.48 HP15_243 argininosuccinate lyase 0.45 HP15_538 2-isopropylmalate synthase — —
Pseudomonas stutzeri RCH2 0.46 Psest_3751 argininosuccinate lyase 0.46 Psest_1056 2-isopropylmalate synthase, bacterial type — —
Phaeobacter inhibens DSM 17395 0.45 PGA1_c03450 argininosuccinate lyase ArgH 0.39 PGA1_c26470 2-isopropylmalate synthase LeuA — —
Rhizobium sp. OAE497 0.44 ABIE40_RS17520 argininosuccinate lyase 0.14 ABIE40_RS06220 citramalate synthase — —
Variovorax sp. OAS795 0.44 ABID97_RS08190 argininosuccinate lyase 0.40 ABID97_RS14910 2-isopropylmalate synthase — —
Dechlorosoma suillum PS 0.44 Dsui_0111 argininosuccinate lyase 0.46 Dsui_3519 2-isopropylmalate synthase, bacterial type — —
Sinorhizobium meliloti 1021 0.44 SMc00725 argininosuccinate lyase 0.15 SMc02546 alpha-isopropylmalate/homocitrate synthase family transferase low > 103
Acidovorax sp. GW101-3H11 0.44 Ac3H11_1632 Argininosuccinate lyase (EC 4.3.2.1) 0.40 Ac3H11_530 2-isopropylmalate synthase (EC 2.3.3.13) — —
Bosea sp. OAE506 0.43 ABIE41_RS08750 argininosuccinate lyase 0.41 ABIE41_RS13000 2-isopropylmalate synthase — —
Variovorax sp. SCN45 0.43 GFF3824 Argininosuccinate lyase (EC 4.3.2.1) 0.40 GFF1165 2-isopropylmalate synthase (EC 2.3.3.13) — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.43 GFF736 Argininosuccinate lyase (EC 4.3.2.1) 0.40 GFF4281 2-isopropylmalate synthase (EC 2.3.3.13) — —
Synechococcus elongatus PCC 7942 0.42 Synpcc7942_2475 argH argininosuccinate lyase 0.40 Synpcc7942_1410 leuA 2-isopropylmalate synthase — —
Rhodopseudomonas palustris CGA009 0.42 TX73_024645 argininosuccinate lyase 0.41 TX73_010545 2-isopropylmalate synthase — —
Dinoroseobacter shibae DFL-12 0.42 Dshi_3062 argininosuccinate lyase (RefSeq) 0.38 Dshi_0596 2-isopropylmalate synthase (RefSeq) 0.77 13
Ralstonia sp. UNC404CL21Col 0.42 ABZR87_RS16170 argininosuccinate lyase 0.41 ABZR87_RS14930 2-isopropylmalate synthase low > 80
Desulfovibrio vulgaris Hildenborough JW710 0.42 DVU1094 argH argininosuccinate lyase (TIGR) 0.43 DVU2981 leuA 2-isopropylmalate synthase (TIGR) 0.88 17
Paraburkholderia graminis OAS925 0.41 ABIE53_001311 argininosuccinate lyase 0.42 ABIE53_001580 2-isopropylmalate synthase — —
Paraburkholderia bryophila 376MFSha3.1 0.41 H281DRAFT_00194 argininosuccinate lyase 0.42 H281DRAFT_04556 2-isopropylmalate synthase low > 103
Ralstonia solanacearum UW163 0.41 UW163_RS09390 argininosuccinate lyase 0.41 UW163_RS10700 2-isopropylmalate synthase — —
Ralstonia solanacearum IBSBF1503 0.41 RALBFv3_RS04280 argininosuccinate lyase 0.41 RALBFv3_RS03025 2-isopropylmalate synthase — —
Cupriavidus basilensis FW507-4G11 0.41 RR42_RS15925 argininosuccinate lyase 0.40 RR42_RS05465 2-isopropylmalate synthase — —
Ralstonia solanacearum GMI1000 0.41 RS_RS11865 argininosuccinate lyase 0.41 RS_RS10395 2-isopropylmalate synthase — —
Burkholderia phytofirmans PsJN 0.41 BPHYT_RS05210 argininosuccinate lyase 0.41 BPHYT_RS06570 2-isopropylmalate synthase — —
Desulfovibrio vulgaris Miyazaki F 0.41 DvMF_0048 argininosuccinate lyase (RefSeq) 0.43 DvMF_1791 2-isopropylmalate synthase (RefSeq) 0.92 20
Magnetospirillum magneticum AMB-1 0.41 AMB_RS22715 argininosuccinate lyase 0.41 AMB_RS17765 2-isopropylmalate synthase — —
Caulobacter crescentus NA1000 0.41 CCNA_02294 argininosuccinate lyase 0.40 CCNA_01610 2-isopropylmalate synthase — —
Caulobacter crescentus NA1000 Δfur 0.41 CCNA_02294 argininosuccinate lyase 0.40 CCNA_01610 2-isopropylmalate synthase — —
Paraburkholderia sabiae LMG 24235 0.40 QEN71_RS24970 argininosuccinate lyase 0.41 QEN71_RS24195 2-isopropylmalate synthase low > 153
Ralstonia solanacearum PSI07 0.40 RPSI07_RS13080 argininosuccinate lyase 0.41 RPSI07_RS14285 2-isopropylmalate synthase — —
Methanococcus maripaludis JJ 0.31 MMJJ_RS05395 argininosuccinate lyase 0.28 MMJJ_RS08870 2-isopropylmalate synthase — —
Methanococcus maripaludis S2 0.31 MMP_RS00095 argininosuccinate lyase 0.28 MMP_RS05500 2-isopropylmalate synthase — —
Phocaeicola dorei CL03T12C01 0.25 ABI39_RS07095 argininosuccinate lyase 0.43 ABI39_RS10195 2-isopropylmalate synthase 0.80 37
Phocaeicola vulgatus CL09T03C04 0.25 HMPREF1058_RS09585 argininosuccinate lyase 0.43 HMPREF1058_RS14545 2-isopropylmalate synthase 0.69 24
Bacteroides ovatus ATCC 8483 0.24 BACOVA_03551 argininosuccinate lyase 0.42 BACOVA_04604 2-isopropylmalate synthase 0.95 14
Bacteroides stercoris CC31F 0.24 HMPREF1181_RS03410 argininosuccinate lyase 0.42 HMPREF1181_RS14150 2-isopropylmalate synthase 0.91 31
Lysobacter sp. OAE881 0.22 ABIE51_RS13380 argininosuccinate lyase 0.39 ABIE51_RS17570 2-isopropylmalate synthase low > 62
Rhodanobacter sp. FW510-T8 0.20 OKGIIK_09430 argH argininosuccinate lyase 0.39 OKGIIK_13575 leuA 2-isopropylmalate synthase low > 52
Rhodanobacter denitrificans MT42 0.20 LRK55_RS02135 argininosuccinate lyase 0.40 LRK55_RS09985 2-isopropylmalate synthase low > 63
Rhodanobacter denitrificans FW104-10B01 0.20 LRK54_RS02380 argininosuccinate lyase 0.40 LRK54_RS10345 2-isopropylmalate synthase low > 59
Dyella japonica UNC79MFTsu3.2 0.20 ABZR86_RS08695 arginosuccinate lyase (EC 4.3.2.1) (from data) 0.42 ABZR86_RS15970 2-isopropylmalate synthase 0.96 5
Xanthomonas campestris pv. campestris strain 8004 0.19 Xcc-8004.2323.1 Argininosuccinate lyase (EC 4.3.2.1) 0.38 Xcc-8004.1056.1 2-isopropylmalate synthase (EC 2.3.3.13) 0.74 61

Not shown: 30 genomes with orthologs for BWI76_RS00855 only; 2 genomes with orthologs for BWI76_RS04680 only