Conservation of cofitness between BWI76_RS25320 and BWI76_RS00805 in Klebsiella michiganensis M5al

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS25320 glutamate synthase 1.0 BWI76_RS00805 5,10-methylenetetrahydrofolate reductase 0.66 16
Enterobacter asburiae PDN3 0.98 EX28DRAFT_3276 glutamate synthase small subunit family protein, proteobacterial 0.95 EX28DRAFT_4413 5,10-methylenetetrahydrofolate reductase, prokaryotic form low > 76
Enterobacter sp. TBS_079 0.98 MPMX20_04127 Glutamate synthase [NADPH] small chain 0.95 MPMX20_04529 5,10-methylenetetrahydrofolate reductase 0.48 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF2957 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) 0.96 GFF2329 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) low > 78
Escherichia coli ECOR27 0.95 NOLOHH_09680 gltD glutamate synthase subunit GltD 0.95 NOLOHH_05810 metF methylenetetrahydrofolate reductase 0.94 9
Escherichia coli BW25113 0.95 b3213 gltD glutamate synthase, 4Fe-4S protein, small subunit (NCBI) 0.95 b3941 metF 5,10-methylenetetrahydrofolate reductase (NCBI) 0.55 20
Escherichia fergusonii Becca 0.95 EFB2_00610 Glutamate synthase [NADPH] small chain 0.94 EFB2_04672 5,10-methylenetetrahydrofolate reductase low > 86
Escherichia coli ECRC98 0.95 JDDGAC_21505 gltD glutamate synthase subunit GltD 0.95 JDDGAC_17290 metF methylenetetrahydrofolate reductase 0.91 29
Escherichia coli ECRC101 0.95 MCAODC_08400 gltD glutamate synthase subunit GltD 0.95 MCAODC_04165 metF methylenetetrahydrofolate reductase low > 87
Escherichia coli ECRC102 0.95 NIAGMN_15640 gltD glutamate synthase subunit GltD 0.95 NIAGMN_11420 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC62 0.95 BNILDI_01855 gltD glutamate synthase subunit GltD 0.95 BNILDI_05725 metF methylenetetrahydrofolate reductase 0.90 7
Escherichia coli ECRC99 0.95 KEDOAH_10270 gltD glutamate synthase subunit GltD 0.95 KEDOAH_14495 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC100 0.95 OKFHMN_17880 gltD glutamate synthase subunit GltD 0.95 OKFHMN_13665 metF methylenetetrahydrofolate reductase 0.92 10
Escherichia coli ECOR38 0.95 HEPCGN_16755 gltD glutamate synthase subunit GltD 0.95 HEPCGN_12310 metF methylenetetrahydrofolate reductase 0.93 7
Escherichia coli HS(pFamp)R (ATCC 700891) 0.95 OHPLBJKB_00487 Glutamate synthase [NADPH] small chain 0.95 OHPLBJKB_04109 5,10-methylenetetrahydrofolate reductase low > 73
Escherichia coli BL21 0.95 ECD_03078 glutamate synthase, 4Fe-4S protein, small subunit 0.95 ECD_03827 5,10-methylenetetrahydrofolate reductase 0.66 25
Escherichia coli Nissle 1917 0.95 ECOLIN_RS18480 glutamate synthase subunit GltD 0.94 ECOLIN_RS22760 methylenetetrahydrofolate reductase low > 55
Erwinia tracheiphila SCR3 0.90 LU632_RS21320 glutamate synthase small subunit 0.87 LU632_RS19630 metF methylenetetrahydrofolate reductase low > 74
Dickeya dadantii 3937 0.89 DDA3937_RS01660 FAD-dependent oxidoreductase 0.91 DDA3937_RS00960 methylenetetrahydrofolate reductase low > 74
Rahnella sp. WP5 0.88 EX31_RS12510 FAD-dependent oxidoreductase 0.91 EX31_RS14205 methylenetetrahydrofolate reductase 0.89 63
Pectobacterium carotovorum WPP14 0.88 HER17_RS19915 glutamate synthase small subunit 0.90 HER17_RS00950 methylenetetrahydrofolate reductase low > 75
Dickeya dianthicola 67-19 0.88 HGI48_RS01555 glutamate synthase small subunit 0.90 HGI48_RS20415 methylenetetrahydrofolate reductase low > 71
Dickeya dianthicola ME23 0.88 DZA65_RS01630 FAD-dependent oxidoreductase 0.90 DZA65_RS21460 methylenetetrahydrofolate reductase 0.73 46
Serratia liquefaciens MT49 0.86 IAI46_22350 glutamate synthase small subunit 0.92 IAI46_24530 methylenetetrahydrofolate reductase 0.68 54
Vibrio cholerae E7946 ATCC 55056 0.74 CSW01_12035 glutamate synthase small subunit 0.78 CSW01_13560 methylenetetrahydrofolate reductase low > 62
Alteromonas macleodii MIT1002 0.72 MIT1002_03140 Glutamate synthase [NADPH] small chain 0.70 MIT1002_03670 5,10-methylenetetrahydrofolate reductase low > 70
Acinetobacter radioresistens SK82 0.69 MPMX26_02807 Glutamate synthase [NADPH] small chain 0.32 MPMX26_01002 5,10-methylenetetrahydrofolate reductase low > 36
Shewanella oneidensis MR-1 0.68 SO1324 gltD glutamate synthase, small subunit (NCBI ptt file) 0.76 SO4054 metF 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.84 42
Shewanella loihica PV-4 0.68 Shew_1031 gltD glutamate synthase subunit beta (RefSeq) 0.75 Shew_0522 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.98 8
Shewanella sp. ANA-3 0.68 Shewana3_3051 gltD glutamate synthase subunit beta (RefSeq) 0.76 Shewana3_3612 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.92 3
Shewanella amazonensis SB2B 0.68 Sama_0856 gltD glutamate synthase subunit beta (RefSeq) 0.76 Sama_3169 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.84 18
Pseudomonas fluorescens FW300-N2E2 0.68 Pf6N2E2_3751 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) 0.37 Pf6N2E2_4638 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.60 39
Pseudomonas stutzeri RCH2 0.68 Psest_3710 glutamate synthase small subunit family protein, proteobacterial 0.36 Psest_0313 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.41 25
Pseudomonas putida KT2440 0.68 PP_5075 glutamate synthase (NADPH) beta subunit 0.36 PP_4977 5,10-methylenetetrahydrofolate reductase low > 96
Pseudomonas syringae pv. syringae B728a 0.68 Psyr_0412 glutamate synthase (NADPH) small subunit 0.36 Psyr_0459 5,10-methylenetetrahydrofolate reductase 0.52 66
Pseudomonas sp. RS175 0.68 PFR28_05016 Glutamate synthase [NADPH] small chain 0.38 PFR28_04202 5,10-methylenetetrahydrofolate reductase 0.30 39
Pseudomonas fluorescens FW300-N2C3 0.68 AO356_09370 glutamate synthase 0.36 AO356_13605 5,10-methylenetetrahydrofolate reductase 0.75 6
Pseudomonas syringae pv. syringae B728a ΔmexB 0.68 Psyr_0412 glutamate synthase (NADPH) small subunit 0.36 Psyr_0459 5,10-methylenetetrahydrofolate reductase low > 86
Pseudomonas sp. S08-1 0.67 OH686_10000 Glutamate synthase [NADPH] small chain 0.37 OH686_10820 methylenetetrahydrofolate reductase [NAD(P)H] 0.77 30
Pseudomonas fluorescens FW300-N2E3 0.67 AO353_12520 glutamate synthase 0.36 AO353_08015 5,10-methylenetetrahydrofolate reductase 0.69 33
Pseudomonas fluorescens FW300-N1B4 0.67 Pf1N1B4_1533 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) 0.37 Pf1N1B4_2384 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.69 39
Pseudomonas fluorescens GW456-L13 0.67 PfGW456L13_271 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) 0.36 PfGW456L13_1050 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.43 37
Pseudomonas simiae WCS417 0.67 PS417_02005 glutamate synthase 0.37 PS417_26510 5,10-methylenetetrahydrofolate reductase 0.38 88
Pseudomonas fluorescens SBW25 0.67 PFLU_RS02050 NAD(P)-binding protein 0.37 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H] low > 109
Pseudomonas fluorescens SBW25-INTG 0.67 PFLU_RS02050 NAD(P)-binding protein 0.37 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H] low > 109
Marinobacter adhaerens HP15 0.65 HP15_483 oxidoreductase Fe-S binding subunit 0.37 HP15_2917 5,10-methylenetetrahydrofolate reductase-like protein
Lysobacter sp. OAE881 0.59 ABIE51_RS01315 FAD-dependent oxidoreductase 0.35 ABIE51_RS16490 methylenetetrahydrofolate reductase [NAD(P)H] 0.98 10
Xanthomonas campestris pv. campestris strain 8004 0.57 Xcc-8004.43.1 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) 0.37 Xcc-8004.4336.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) low > 74
Rhodanobacter denitrificans FW104-10B01 0.54 LRK54_RS10965 FAD-dependent oxidoreductase 0.37 LRK54_RS12030 methylenetetrahydrofolate reductase [NAD(P)H] 0.81 23
Rhodanobacter denitrificans MT42 0.54 LRK55_RS10670 FAD-dependent oxidoreductase 0.37 LRK55_RS11765 methylenetetrahydrofolate reductase [NAD(P)H] low > 63
Dyella japonica UNC79MFTsu3.2 0.52 ABZR86_RS16800 FAD-dependent oxidoreductase 0.36 ABZR86_RS11570 methylenetetrahydrofolate reductase [NAD(P)H] 0.87 42
Dinoroseobacter shibae DFL-12 0.41 Dshi_0001 glutamate synthase, small subunit (RefSeq) 0.37 Dshi_2080 5,10-methylenetetrahydrofolate reductase (RefSeq)
Sphingomonas koreensis DSMZ 15582 0.40 Ga0059261_1797 glutamate synthase small subunit family protein, proteobacterial 0.54 Ga0059261_0992 5,10-methylenetetrahydrofolate reductase, prokaryotic form low > 68
Phaeobacter inhibens DSM 17395 0.40 PGA1_c36090 glutamate synthase [NADPH] small chain 0.40 PGA1_c11700 5,10-methylenetetrahydrofolate reductase MetF 0.70 22
Azospirillum sp. SherDot2 0.38 MPMX19_02658 Glutamate synthase [NADPH] small chain 0.55 MPMX19_00635 5,10-methylenetetrahydrofolate reductase 0.82 20
Magnetospirillum magneticum AMB-1 0.38 AMB_RS02690 dihydropyrimidine dehydrogenase subunit A 0.55 AMB_RS02230 methylenetetrahydrofolate reductase
Caulobacter crescentus NA1000 0.38 CCNA_03721 glutamate synthase (NADPH) small chain GltD 0.48 CCNA_02224 methylenetetrahydrofolate reductase 0.89 20
Caulobacter crescentus NA1000 Δfur 0.38 CCNA_03721 glutamate synthase (NADPH) small chain GltD 0.48 CCNA_02224 methylenetetrahydrofolate reductase low > 67
Rhodospirillum rubrum S1H 0.38 Rru_A0018 Glutamate synthase, NADH/NADPH, small subunit 2 (NCBI) 0.52 Rru_A1530 5,10-methylenetetrahydrofolate reductase (NCBI)
Brevundimonas sp. GW460-12-10-14-LB2 0.35 A4249_RS16110 NAD(P)-dependent oxidoreductase 0.46 A4249_RS07925 methylenetetrahydrofolate reductase [NAD(P)H] 0.98 31
Parabacteroides merdae CL09T00C40 0.28 HMPREF1078_RS11400 NADPH-dependent glutamate synthase 0.21 HMPREF1078_RS07860 methylenetetrahydrofolate reductase [NAD(P)H] low > 61
Rhizobium sp. OAE497 0.27 ABIE40_RS16270 glutamate synthase subunit beta 0.41 ABIE40_RS11950 methylenetetrahydrofolate reductase [NAD(P)H]
Ralstonia sp. UNC404CL21Col 0.27 ABZR87_RS02565 glutamate synthase subunit beta 0.38 ABZR87_RS04865 methylenetetrahydrofolate reductase [NAD(P)H] 0.70 29
Bifidobacterium breve UCC2003 0.26 BBR_RS15260 glutamate synthase subunit beta 0.23 BBR_RS15410 methylenetetrahydrofolate reductase [NAD(P)H] low > 34
Cupriavidus basilensis FW507-4G11 0.26 RR42_RS18985 glutamate synthase 0.39 RR42_RS01385 5,10-methylenetetrahydrofolate reductase 0.61 24
Castellaniella sp019104865 MT123 0.26 ABCV34_RS11155 glutamate synthase subunit beta 0.35 ABCV34_RS13550 methylenetetrahydrofolate reductase [NAD(P)H] low > 48
Variovorax sp. OAS795 0.25 ABID97_RS23220 glutamate synthase subunit beta 0.33 ABID97_RS25015 methylenetetrahydrofolate reductase [NAD(P)H] 0.63 4
Ralstonia solanacearum GMI1000 0.25 RS_RS14855 glutamate synthase subunit beta 0.38 RS_RS00460 methylenetetrahydrofolate reductase [NAD(P)H] 0.74 6
Hydrogenophaga sp. GW460-11-11-14-LB1 0.25 GFF1326 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) 0.34 GFF1692 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Paraburkholderia sabiae LMG 24235 0.25 QEN71_RS28005 glutamate synthase subunit beta 0.41 QEN71_RS28715 methylenetetrahydrofolate reductase [NAD(P)H] 0.76 16
Ralstonia solanacearum UW163 0.25 UW163_RS06705 glutamate synthase subunit beta 0.38 UW163_RS03705 methylenetetrahydrofolate reductase [NAD(P)H]
Ralstonia solanacearum IBSBF1503 0.25 RALBFv3_RS06910 glutamate synthase subunit beta 0.38 RALBFv3_RS09875 methylenetetrahydrofolate reductase [NAD(P)H] 0.57 7
Sinorhizobium meliloti 1021 0.25 SMc04026 glutamate synthase 0.37 SMc01843 5,10-methylenetetrahydrofolate reductase 0.88 9
Ralstonia solanacearum PSI07 0.25 RPSI07_RS10325 glutamate synthase subunit beta 0.38 RPSI07_RS23495 methylenetetrahydrofolate reductase [NAD(P)H] 0.69 2
Agrobacterium fabrum C58 0.25 Atu3783 glutamate synthase subunit beta 0.39 Atu2123 methylenetetrahydrofolate reductase 0.62 81
Dechlorosoma suillum PS 0.25 Dsui_1097 NADH/NADPH-dependent glutamate synthase small subunit 0.39 Dsui_0640 5,10-methylenetetrahydrofolate reductase
Bosea sp. OAE506 0.24 ABIE41_RS08570 glutamate synthase subunit beta 0.52 ABIE41_RS12475 methylenetetrahydrofolate reductase [NAD(P)H]
Acidovorax sp. GW101-3H11 0.24 Ac3H11_4711 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) 0.34 Ac3H11_3045 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.73 4
Rhodanobacter sp. FW510-T8 0.23 OKGIIK_15205 Glutamate synthase 0.36 OKGIIK_11830 metF methylenetetrahydrofolate reductase [NAD(P)H] low > 52
Variovorax sp. SCN45 0.23 GFF5333 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) 0.32 GFF2055 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.76 33
Phocaeicola dorei CL03T12C01 0.22 ABI39_RS20690 glutamate synthase subunit beta 0.19 ABI39_RS15570 methylenetetrahydrofolate reductase [NAD(P)H] low > 72

Not shown: 1 genomes with orthologs for BWI76_RS25320 only; 19 genomes with orthologs for BWI76_RS00805 only