Conservation of cofitness between BPHYT_RS33900 and BPHYT_RS33835 in Burkholderia phytofirmans PsJN

79 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Burkholderia phytofirmans PsJN 1.0 BPHYT_RS33900 3-isopropylmalate dehydrogenase 1.0 BPHYT_RS33835 O-succinylhomoserine sulfhydrylase 0.96 3
Paraburkholderia graminis OAS925 0.98 ABIE53_004804 3-isopropylmalate dehydrogenase 0.93 ABIE53_004817 O-succinylhomoserine sulfhydrylase 0.96 3
Paraburkholderia bryophila 376MFSha3.1 0.98 H281DRAFT_06072 3-isopropylmalate dehydrogenase 0.94 H281DRAFT_06059 O-succinylhomoserine sulfhydrylase 0.73 6
Paraburkholderia sabiae LMG 24235 0.96 QEN71_RS17620 3-isopropylmalate dehydrogenase 0.88 QEN71_RS17685 O-succinylhomoserine sulfhydrylase low > 153
Cupriavidus basilensis FW507-4G11 0.89 RR42_RS14385 3-isopropylmalate dehydrogenase 0.73 RR42_RS14320 O-succinylhomoserine sulfhydrylase 0.80 13
Variovorax sp. SCN45 0.79 GFF3888 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.56 GFF3088 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) — —
Variovorax sp. OAS795 0.79 ABID97_RS08455 3-isopropylmalate dehydrogenase 0.58 ABID97_RS21630 O-succinylhomoserine sulfhydrylase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.77 GFF3360 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.60 GFF301 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.82 18
Castellaniella sp019104865 MT123 0.75 ABCV34_RS04280 3-isopropylmalate dehydrogenase 0.34 ABCV34_RS15785 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme low > 48
Dechlorosoma suillum PS 0.68 Dsui_3198 3-isopropylmalate dehydrogenase 0.65 Dsui_3185 O-succinylhomoserine sulfhydrylase — —
Pseudomonas fluorescens FW300-N2E3 0.65 AO353_20635 3-isopropylmalate dehydrogenase 0.55 AO353_20695 O-succinylhomoserine sulfhydrylase 0.96 8
Pseudomonas fluorescens FW300-N1B4 0.65 Pf1N1B4_12 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.33 Pf1N1B4_4890 Cystathionine gamma-lyase (EC 4.4.1.1) low > 87
Pseudomonas fluorescens FW300-N2E2 0.64 Pf6N2E2_66 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.55 Pf6N2E2_77 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.94 7
Pseudomonas fluorescens FW300-N2C3 0.64 AO356_21415 3-isopropylmalate dehydrogenase 0.55 AO356_21470 O-succinylhomoserine sulfhydrylase 0.96 4
Pseudomonas putida KT2440 0.64 PP_1988 3-isopropylmalate dehydrogenase 0.53 PP_2001 O-succinylhomoserine sulfhydrylase 0.89 15
Pseudomonas fluorescens GW456-L13 0.64 PfGW456L13_3945 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.55 PfGW456L13_3934 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.97 4
Pseudomonas sp. RS175 0.64 PFR28_02821 3-isopropylmalate dehydrogenase 0.55 PFR28_02810 O-succinylhomoserine sulfhydrylase 0.52 29
Marinobacter adhaerens HP15 0.64 HP15_1832 3-isopropylmalate dehydrogenase 0.55 HP15_1820 methionine gamma-lyase 0.91 10
Pseudomonas simiae WCS417 0.64 PS417_18585 3-isopropylmalate dehydrogenase 0.55 PS417_18530 O-succinylhomoserine sulfhydrylase 0.91 8
Pseudomonas fluorescens SBW25 0.63 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.55 PFLU_RS20510 O-succinylhomoserine sulfhydrylase 0.86 3
Pseudomonas fluorescens SBW25-INTG 0.63 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.55 PFLU_RS20510 O-succinylhomoserine sulfhydrylase 0.87 6
Kangiella aquimarina DSM 16071 0.63 B158DRAFT_1322 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.40 B158DRAFT_1522 methionine gamma-lyase low > 40
Pseudomonas syringae pv. syringae B728a 0.63 Psyr_1985 3-isopropylmalate dehydrogenase 0.57 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.97 2
Pseudomonas stutzeri RCH2 0.63 Psest_2589 3-isopropylmalate dehydrogenase 0.54 Psest_2578 O-succinylhomoserine sulfhydrylase 0.95 2
Pseudomonas syringae pv. syringae B728a ΔmexB 0.63 Psyr_1985 3-isopropylmalate dehydrogenase 0.57 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.97 1
Pseudomonas sp. S08-1 0.62 OH686_04470 3-isopropylmalate dehydrogenase 0.56 OH686_04415 O-succinylhomoserine sulfhydrylase 0.83 17
Sphingomonas koreensis DSMZ 15582 0.60 Ga0059261_3190 3-isopropylmalate dehydrogenase 0.48 Ga0059261_3194 O-acetylhomoserine sulfhydrylase (EC:2.5.1.49) (from data) 0.87 57
Xanthomonas campestris pv. campestris strain 8004 0.60 Xcc-8004.1053.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.33 Xcc-8004.4517.1 Cystathionine gamma-lyase (EC 4.4.1.1) low > 74
Acinetobacter radioresistens SK82 0.59 MPMX26_00348 3-isopropylmalate dehydrogenase 0.58 MPMX26_01645 O-succinylhomoserine sulfhydrylase 0.90 26
Phaeobacter inhibens DSM 17395 0.54 PGA1_c29830 3-isopropylmalate dehydrogenase LeuB 0.49 PGA1_c23540 O-succinylhomoserine sulfhydrylase MetZ 0.85 27
Dinoroseobacter shibae DFL-12 0.52 Dshi_0081 3-isopropylmalate dehydrogenase (RefSeq) 0.49 Dshi_2410 O-succinylhomoserine sulfhydrylase (RefSeq) — —
Magnetospirillum magneticum AMB-1 0.52 AMB_RS20570 3-isopropylmalate dehydrogenase 0.50 AMB_RS21365 O-succinylhomoserine sulfhydrylase — —
Rhizobium sp. OAE497 0.52 ABIE40_RS19050 3-isopropylmalate dehydrogenase 0.45 ABIE40_RS02340 O-succinylhomoserine sulfhydrylase 0.98 7
Azospirillum sp. SherDot2 0.51 MPMX19_00607 3-isopropylmalate dehydrogenase 0.46 MPMX19_01364 O-succinylhomoserine sulfhydrylase 0.95 3
Bosea sp. OAE506 0.51 ABIE41_RS11860 3-isopropylmalate dehydrogenase 0.48 ABIE41_RS03970 O-succinylhomoserine sulfhydrylase — —
Rhodospirillum rubrum S1H 0.51 Rru_A1191 3-isopropylmalate dehydrogenase (NCBI) 0.48 Rru_A3214 O-succinylhomoserine sulfhydrylase (NCBI) 0.81 32
Sinorhizobium meliloti 1021 0.50 SMc04405 3-isopropylmalate dehydrogenase 0.45 SMc02217 O-succinylhomoserine sulfhydrylase 0.97 7
Klebsiella michiganensis M5al 0.50 BWI76_RS04675 3-isopropylmalate dehydrogenase 0.32 BWI76_RS24210 cystathionine gamma-lyase low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.50 GFF165 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.31 GFF2323 Cystathionine gamma-synthase (EC 2.5.1.48) low > 78
Dickeya dianthicola ME23 0.50 DZA65_RS19205 3-isopropylmalate dehydrogenase 0.31 DZA65_RS21470 cystathionine gamma-synthase 0.88 7
Pectobacterium carotovorum WPP14 0.49 HER17_RS03080 3-isopropylmalate dehydrogenase 0.34 HER17_RS07405 PLP-dependent aspartate aminotransferase family protein low > 75
Agrobacterium fabrum C58 0.49 Atu2791 3-isopropylmalate dehydrogenase 0.45 Atu0432 O-succinylhomoserine sulfhydrylase 0.96 6
Dickeya dianthicola 67-19 0.49 HGI48_RS18060 3-isopropylmalate dehydrogenase 0.31 HGI48_RS20425 cystathionine gamma-synthase 0.83 22
Dickeya dadantii 3937 0.49 DDA3937_RS18120 3-isopropylmalate dehydrogenase 0.31 DDA3937_RS00950 cystathionine gamma-synthase 0.72 28
Enterobacter sp. TBS_079 0.49 MPMX20_00768 3-isopropylmalate dehydrogenase 0.31 MPMX20_01953 Cystathionine beta-lyase low > 85
Enterobacter asburiae PDN3 0.49 EX28DRAFT_3669 3-isopropylmalate dehydrogenase 0.31 EX28DRAFT_1678 Cystathionine beta-lyases/cystathionine gamma-synthases low > 76
Escherichia coli ECOR38 0.49 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase 0.31 HEPCGN_12345 metB cystathionine gamma-synthase 0.94 41
Escherichia fergusonii Becca 0.49 EFB2_03972 3-isopropylmalate dehydrogenase 0.31 EFB2_04679 Cystathionine gamma-synthase low > 86
Azospirillum brasilense Sp245 0.49 AZOBR_RS14130 3-isopropylmalate dehydrogenase 0.46 AZOBR_RS02140 O-succinylhomoserine sulfhydrylase 0.87 6
Escherichia coli Nissle 1917 0.49 ECOLIN_RS00395 3-isopropylmalate dehydrogenase 0.31 ECOLIN_RS22725 cystathionine gamma-synthase 0.96 7
Escherichia coli ECRC102 0.49 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase 0.31 NIAGMN_11430 metB cystathionine gamma-synthase — —
Escherichia coli ECRC101 0.49 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase 0.31 MCAODC_04175 metB cystathionine gamma-synthase 0.95 17
Escherichia coli ECRC100 0.49 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase 0.31 OKFHMN_13675 metB cystathionine gamma-synthase 0.98 26
Escherichia coli ECRC98 0.49 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase 0.31 JDDGAC_17300 metB cystathionine gamma-synthase 1.00 2
Escherichia coli ECRC99 0.49 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase 0.31 KEDOAH_14485 metB cystathionine gamma-synthase — —
Escherichia coli ECOR27 0.49 NOLOHH_03065 leuA 2-isopropylmalate synthase 0.31 NOLOHH_05820 metB cystathionine gamma-synthase 0.92 38
Escherichia coli HS(pFamp)R (ATCC 700891) 0.49 OHPLBJKB_03584 3-isopropylmalate dehydrogenase 0.31 OHPLBJKB_04111 Cystathionine gamma-synthase low > 73
Escherichia coli ECRC62 0.49 BNILDI_08545 leuA 2-isopropylmalate synthase 0.31 BNILDI_05715 metB cystathionine gamma-synthase 0.95 39
Escherichia coli BW25113 0.49 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) 0.31 b3939 metB cystathionine gamma-synthase (NCBI) 0.90 42
Escherichia coli BL21 0.49 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent 0.31 ECD_03825 cystathionine gamma-synthase, PLP-dependent 0.95 14
Vibrio cholerae E7946 ATCC 55056 0.49 CSW01_12600 3-isopropylmalate dehydrogenase 0.27 CSW01_13550 O-succinylhomoserine (thiol)-lyase low > 62
Shewanella loihica PV-4 0.48 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) 0.35 Shew_2491 methionine gamma-lyase (RefSeq) low > 60
Shewanella oneidensis MR-1 0.48 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.40 SO1812 mdeA Methionine gamma-lyase (EC 4.4.1.11) (from data) low > 76
Rhodopseudomonas palustris CGA009 0.48 TX73_001175 3-isopropylmalate dehydrogenase 0.48 TX73_024775 O-succinylhomoserine sulfhydrylase — —
Shewanella sp. ANA-3 0.48 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) 0.40 Shewana3_2643 methionine gamma-lyase (RefSeq) low > 73
Pedobacter sp. GW460-11-11-14-LB5 0.48 CA265_RS15850 3-isopropylmalate dehydrogenase 0.46 CA265_RS13080 O-succinylhomoserine sulfhydrylase 0.92 20
Caulobacter crescentus NA1000 Δfur 0.48 CCNA_00193 3-isopropylmalate dehydrogenase 0.44 CCNA_02321 O-succinylhomoserine sulfhydrylase low > 67
Caulobacter crescentus NA1000 0.48 CCNA_00193 3-isopropylmalate dehydrogenase 0.44 CCNA_02321 O-succinylhomoserine sulfhydrylase 0.93 22
Pantoea sp. MT58 0.47 IAI47_16005 3-isopropylmalate dehydrogenase 0.28 IAI47_00880 cystathionine gamma-synthase 0.98 4
Erwinia tracheiphila SCR3 0.47 LU632_RS02875 leuB 3-isopropylmalate dehydrogenase 0.30 LU632_RS19640 metB cystathionine gamma-synthase 0.82 16
Mucilaginibacter yixingensis YX-36 DSM 26809 0.47 ABZR88_RS11605 3-isopropylmalate dehydrogenase 0.31 ABZR88_RS06685 cystathionine gamma-synthase — —
Shewanella amazonensis SB2B 0.47 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) 0.37 Sama_1242 methionine gamma-lyase (RefSeq) low > 62
Lysobacter sp. OAE881 0.44 ABIE51_RS17585 3-isopropylmalate dehydrogenase 0.33 ABIE51_RS04295 cystathionine gamma-synthase low > 62
Echinicola vietnamensis KMM 6221, DSM 17526 0.44 Echvi_2062 3-isopropylmalate dehydrogenase 0.48 Echvi_2283 Cystathionine beta-lyases/cystathionine gamma-synthases — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.43 CA264_09445 3-isopropylmalate dehydrogenase 0.45 CA264_02530 O-succinylhomoserine sulfhydrylase low > 74
Brevundimonas sp. GW460-12-10-14-LB2 0.42 A4249_RS09995 3-isopropylmalate dehydrogenase 0.34 A4249_RS08315 cystathionine gamma-synthase low > 48
Rhodanobacter sp. FW510-T8 0.42 OKGIIK_13595 leuB 3-isopropylmalate dehydrogenase 0.33 OKGIIK_01180 metC cystathionine beta-lyase low > 52
Rhodanobacter denitrificans MT42 0.41 LRK55_RS09965 3-isopropylmalate dehydrogenase 0.32 LRK55_RS05410 cystathionine gamma-synthase low > 63
Rhodanobacter denitrificans FW104-10B01 0.41 LRK54_RS10325 3-isopropylmalate dehydrogenase 0.32 LRK54_RS05660 PLP-dependent aspartate aminotransferase family protein low > 59
Dyella japonica UNC79MFTsu3.2 0.40 ABZR86_RS15950 3-isopropylmalate dehydrogenase 0.34 ABZR86_RS18745 PLP-dependent aspartate aminotransferase family protein — —

Not shown: 20 genomes with orthologs for BPHYT_RS33900 only; 2 genomes with orthologs for BPHYT_RS33835 only