| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Burkholderia phytofirmans PsJN | 1.0 | BPHYT_RS18705 | | 5,10-methylenetetrahydrofolate reductase | 1.0 | BPHYT_RS33835 | | O-succinylhomoserine sulfhydrylase | 0.57 | 2 |
| Paraburkholderia graminis OAS925 | 0.97 | ABIE53_000061 | | methylenetetrahydrofolate reductase (NADPH) | 0.93 | ABIE53_004817 | | O-succinylhomoserine sulfhydrylase | 0.93 | 2 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.96 | H281DRAFT_05801 | | 5,10-methylenetetrahydrofolate reductase (NAD(P)) | 0.94 | H281DRAFT_06059 | | O-succinylhomoserine sulfhydrylase | 0.82 | 3 |
| Paraburkholderia sabiae LMG 24235 | 0.92 | QEN71_RS28715 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.88 | QEN71_RS17685 | | O-succinylhomoserine sulfhydrylase | low | > 153 |
| Cupriavidus basilensis FW507-4G11 | 0.80 | RR42_RS01385 | | 5,10-methylenetetrahydrofolate reductase | 0.73 | RR42_RS14320 | | O-succinylhomoserine sulfhydrylase | 0.78 | 12 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.65 | GFF1692 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.60 | GFF301 | | O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | — | — |
| Dechlorosoma suillum PS | 0.64 | Dsui_0640 | | 5,10-methylenetetrahydrofolate reductase | 0.65 | Dsui_3185 | | O-succinylhomoserine sulfhydrylase | — | — |
| Variovorax sp. SCN45 | 0.63 | GFF2055 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.56 | GFF3088 | | O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | — | — |
| Marinobacter adhaerens HP15 | 0.62 | HP15_2917 | | 5,10-methylenetetrahydrofolate reductase-like protein | 0.55 | HP15_1820 | | methionine gamma-lyase | 0.96 | 3 |
| Variovorax sp. OAS795 | 0.62 | ABID97_RS25015 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.58 | ABID97_RS21630 | | O-succinylhomoserine sulfhydrylase | — | — |
| Pseudomonas sp. RS175 | 0.60 | PFR28_04202 | | 5,10-methylenetetrahydrofolate reductase | 0.55 | PFR28_02810 | | O-succinylhomoserine sulfhydrylase | 0.38 | 72 |
| Pseudomonas fluorescens FW300-N2E2 | 0.60 | Pf6N2E2_4638 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.55 | Pf6N2E2_77 | | O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | 0.75 | 7 |
| Pseudomonas fluorescens FW300-N2C3 | 0.60 | AO356_13605 | | 5,10-methylenetetrahydrofolate reductase | 0.55 | AO356_21470 | | O-succinylhomoserine sulfhydrylase | 0.96 | 7 |
| Pseudomonas sp. S08-1 | 0.60 | OH686_10820 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.56 | OH686_04415 | | O-succinylhomoserine sulfhydrylase | 0.89 | 3 |
| Pseudomonas fluorescens SBW25 | 0.59 | PFLU_RS28165 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.55 | PFLU_RS20510 | | O-succinylhomoserine sulfhydrylase | 0.84 | 1 |
| Pseudomonas fluorescens SBW25-INTG | 0.59 | PFLU_RS28165 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.55 | PFLU_RS20510 | | O-succinylhomoserine sulfhydrylase | 0.86 | 1 |
| Rhodanobacter denitrificans FW104-10B01 | 0.59 | LRK54_RS12030 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.32 | LRK54_RS05660 | | PLP-dependent aspartate aminotransferase family protein | low | > 59 |
| Pseudomonas fluorescens FW300-N2E3 | 0.59 | AO353_08015 | | 5,10-methylenetetrahydrofolate reductase | 0.55 | AO353_20695 | | O-succinylhomoserine sulfhydrylase | 0.85 | 13 |
| Pseudomonas simiae WCS417 | 0.59 | PS417_26510 | | 5,10-methylenetetrahydrofolate reductase | 0.55 | PS417_18530 | | O-succinylhomoserine sulfhydrylase | 0.45 | 16 |
| Rhodanobacter denitrificans MT42 | 0.59 | LRK55_RS11765 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.32 | LRK55_RS05410 | | cystathionine gamma-synthase | low | > 63 |
| Pseudomonas fluorescens FW300-N1B4 | 0.59 | Pf1N1B4_2384 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.33 | Pf1N1B4_4890 | | Cystathionine gamma-lyase (EC 4.4.1.1) | low | > 87 |
| Pseudomonas putida KT2440 | 0.59 | PP_4977 | | 5,10-methylenetetrahydrofolate reductase | 0.53 | PP_2001 | | O-succinylhomoserine sulfhydrylase | 0.53 | 16 |
| Castellaniella sp019104865 MT123 | 0.58 | ABCV34_RS13550 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.34 | ABCV34_RS15785 | | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | low | > 48 |
| Rhodanobacter sp. FW510-T8 | 0.58 | OKGIIK_11830 | metF | methylenetetrahydrofolate reductase [NAD(P)H] | 0.33 | OKGIIK_01180 | metC | cystathionine beta-lyase | low | > 52 |
| Pseudomonas fluorescens GW456-L13 | 0.58 | PfGW456L13_1050 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.55 | PfGW456L13_3934 | | O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) | 0.97 | 2 |
| Pseudomonas stutzeri RCH2 | 0.58 | Psest_0313 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.54 | Psest_2578 | | O-succinylhomoserine sulfhydrylase | 0.94 | 1 |
| Lysobacter sp. OAE881 | 0.58 | ABIE51_RS16490 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.33 | ABIE51_RS04295 | | cystathionine gamma-synthase | low | > 62 |
| Dyella japonica UNC79MFTsu3.2 | 0.58 | ABZR86_RS11570 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.34 | ABZR86_RS18745 | | PLP-dependent aspartate aminotransferase family protein | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.57 | Psyr_0459 | | 5,10-methylenetetrahydrofolate reductase | 0.57 | Psyr_1669 | | O-succinylhomoserine sulfhydrylase | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.57 | Psyr_0459 | | 5,10-methylenetetrahydrofolate reductase | 0.57 | Psyr_1669 | | O-succinylhomoserine sulfhydrylase | 0.62 | 19 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.57 | Xcc-8004.4336.1 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.33 | Xcc-8004.4517.1 | | Cystathionine gamma-lyase (EC 4.4.1.1) | low | > 74 |
| Acinetobacter radioresistens SK82 | 0.50 | MPMX26_01002 | | 5,10-methylenetetrahydrofolate reductase | 0.58 | MPMX26_01645 | | O-succinylhomoserine sulfhydrylase | low | > 36 |
| Enterobacter sp. TBS_079 | 0.42 | MPMX20_04529 | | 5,10-methylenetetrahydrofolate reductase | 0.31 | MPMX20_01953 | | Cystathionine beta-lyase | low | > 85 |
| Dickeya dianthicola 67-19 | 0.42 | HGI48_RS20415 | | methylenetetrahydrofolate reductase | 0.31 | HGI48_RS20425 | | cystathionine gamma-synthase | low | > 71 |
| Dickeya dadantii 3937 | 0.42 | DDA3937_RS00960 | | methylenetetrahydrofolate reductase | 0.31 | DDA3937_RS00950 | | cystathionine gamma-synthase | 0.41 | 30 |
| Pectobacterium carotovorum WPP14 | 0.42 | HER17_RS00950 | | methylenetetrahydrofolate reductase | 0.34 | HER17_RS07405 | | PLP-dependent aspartate aminotransferase family protein | low | > 75 |
| Dickeya dianthicola ME23 | 0.42 | DZA65_RS21460 | | methylenetetrahydrofolate reductase | 0.31 | DZA65_RS21470 | | cystathionine gamma-synthase | 0.77 | 5 |
| Enterobacter asburiae PDN3 | 0.42 | EX28DRAFT_4413 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.31 | EX28DRAFT_1678 | | Cystathionine beta-lyases/cystathionine gamma-synthases | low | > 76 |
| Klebsiella michiganensis M5al | 0.42 | BWI76_RS00805 | | 5,10-methylenetetrahydrofolate reductase | 0.32 | BWI76_RS24210 | | cystathionine gamma-lyase | low | > 92 |
| Pantoea sp. MT58 | 0.42 | IAI47_00890 | | methylenetetrahydrofolate reductase | 0.28 | IAI47_00880 | | cystathionine gamma-synthase | 0.46 | 55 |
| Escherichia coli ECRC98 | 0.42 | JDDGAC_17290 | metF | methylenetetrahydrofolate reductase | 0.31 | JDDGAC_17300 | metB | cystathionine gamma-synthase | 0.99 | 7 |
| Escherichia coli ECRC62 | 0.42 | BNILDI_05725 | metF | methylenetetrahydrofolate reductase | 0.31 | BNILDI_05715 | metB | cystathionine gamma-synthase | 0.98 | 22 |
| Escherichia coli ECOR27 | 0.42 | NOLOHH_05810 | metF | methylenetetrahydrofolate reductase | 0.31 | NOLOHH_05820 | metB | cystathionine gamma-synthase | 0.93 | 40 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.42 | OHPLBJKB_04109 | | 5,10-methylenetetrahydrofolate reductase | 0.31 | OHPLBJKB_04111 | | Cystathionine gamma-synthase | low | > 73 |
| Escherichia coli ECRC99 | 0.42 | KEDOAH_14495 | metF | methylenetetrahydrofolate reductase | 0.31 | KEDOAH_14485 | metB | cystathionine gamma-synthase | — | — |
| Escherichia coli ECRC101 | 0.42 | MCAODC_04165 | metF | methylenetetrahydrofolate reductase | 0.31 | MCAODC_04175 | metB | cystathionine gamma-synthase | 0.98 | 2 |
| Escherichia coli ECRC100 | 0.42 | OKFHMN_13665 | metF | methylenetetrahydrofolate reductase | 0.31 | OKFHMN_13675 | metB | cystathionine gamma-synthase | 0.98 | 27 |
| Escherichia coli BL21 | 0.42 | ECD_03827 | | 5,10-methylenetetrahydrofolate reductase | 0.31 | ECD_03825 | | cystathionine gamma-synthase, PLP-dependent | 0.94 | 15 |
| Escherichia coli ECRC102 | 0.42 | NIAGMN_11420 | metF | methylenetetrahydrofolate reductase | 0.31 | NIAGMN_11430 | metB | cystathionine gamma-synthase | — | — |
| Escherichia coli BW25113 | 0.42 | b3941 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI) | 0.31 | b3939 | metB | cystathionine gamma-synthase (NCBI) | 0.88 | 51 |
| Escherichia coli ECOR38 | 0.42 | HEPCGN_12310 | metF | methylenetetrahydrofolate reductase | 0.31 | HEPCGN_12345 | metB | cystathionine gamma-synthase | 0.97 | 3 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.41 | GFF2329 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.31 | GFF2323 | | Cystathionine gamma-synthase (EC 2.5.1.48) | low | > 78 |
| Escherichia fergusonii Becca | 0.41 | EFB2_04672 | | 5,10-methylenetetrahydrofolate reductase | 0.31 | EFB2_04679 | | Cystathionine gamma-synthase | low | > 86 |
| Escherichia coli Nissle 1917 | 0.41 | ECOLIN_RS22760 | | methylenetetrahydrofolate reductase | 0.31 | ECOLIN_RS22725 | | cystathionine gamma-synthase | 0.98 | 5 |
| Erwinia tracheiphila SCR3 | 0.41 | LU632_RS19630 | metF | methylenetetrahydrofolate reductase | 0.30 | LU632_RS19640 | metB | cystathionine gamma-synthase | low | > 74 |
| Azospirillum brasilense Sp245 | 0.40 | AZOBR_RS09540 | | 5 10-methylenetetrahydrofolate reductase | 0.46 | AZOBR_RS02140 | | O-succinylhomoserine sulfhydrylase | 0.81 | 1 |
| Magnetospirillum magneticum AMB-1 | 0.40 | AMB_RS02230 | | methylenetetrahydrofolate reductase | 0.50 | AMB_RS21365 | | O-succinylhomoserine sulfhydrylase | — | — |
| Rhodospirillum rubrum S1H | 0.39 | Rru_A1530 | | 5,10-methylenetetrahydrofolate reductase (NCBI) | 0.48 | Rru_A3214 | | O-succinylhomoserine sulfhydrylase (NCBI) | 0.88 | 20 |
| Azospirillum sp. SherDot2 | 0.39 | MPMX19_00635 | | 5,10-methylenetetrahydrofolate reductase | 0.46 | MPMX19_01364 | | O-succinylhomoserine sulfhydrylase | 0.97 | 1 |
| Sphingomonas koreensis DSMZ 15582 | 0.39 | Ga0059261_0992 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.48 | Ga0059261_3194 | | O-acetylhomoserine sulfhydrylase (EC:2.5.1.49) (from data) | 0.75 | 6 |
| Bosea sp. OAE506 | 0.38 | ABIE41_RS12475 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.48 | ABIE41_RS03970 | | O-succinylhomoserine sulfhydrylase | 0.59 | 8 |
| Vibrio cholerae E7946 ATCC 55056 | 0.38 | CSW01_13560 | | methylenetetrahydrofolate reductase | 0.27 | CSW01_13550 | | O-succinylhomoserine (thiol)-lyase | low | > 62 |
| Shewanella loihica PV-4 | 0.38 | Shew_0522 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.35 | Shew_2491 | | methionine gamma-lyase (RefSeq) | low | > 60 |
| Shewanella amazonensis SB2B | 0.38 | Sama_3169 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.37 | Sama_1242 | | methionine gamma-lyase (RefSeq) | low | > 62 |
| Shewanella sp. ANA-3 | 0.37 | Shewana3_3612 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.40 | Shewana3_2643 | | methionine gamma-lyase (RefSeq) | low | > 73 |
| Shewanella oneidensis MR-1 | 0.36 | SO4054 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) | 0.40 | SO1812 | mdeA | Methionine gamma-lyase (EC 4.4.1.11) (from data) | low | > 76 |
| Kangiella aquimarina DSM 16071 | 0.36 | B158DRAFT_2461 | | 5,10-methylenetetrahydrofolate reductase (NAD(P)) (EC 1.5.1.20) | 0.40 | B158DRAFT_1522 | | methionine gamma-lyase | low | > 40 |
| Caulobacter crescentus NA1000 | 0.36 | CCNA_02224 | | methylenetetrahydrofolate reductase | 0.44 | CCNA_02321 | | O-succinylhomoserine sulfhydrylase | 0.95 | 15 |
| Caulobacter crescentus NA1000 Δfur | 0.36 | CCNA_02224 | | methylenetetrahydrofolate reductase | 0.44 | CCNA_02321 | | O-succinylhomoserine sulfhydrylase | low | > 67 |
| Rhizobium sp. OAE497 | 0.35 | ABIE40_RS11950 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.45 | ABIE40_RS02340 | | O-succinylhomoserine sulfhydrylase | 0.98 | 4 |
| Phaeobacter inhibens DSM 17395 | 0.35 | PGA1_c11700 | | 5,10-methylenetetrahydrofolate reductase MetF | 0.49 | PGA1_c23540 | | O-succinylhomoserine sulfhydrylase MetZ | 0.90 | 11 |
| Agrobacterium fabrum C58 | 0.35 | Atu2123 | | methylenetetrahydrofolate reductase | 0.45 | Atu0432 | | O-succinylhomoserine sulfhydrylase | 0.60 | 9 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.35 | A4249_RS07925 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.34 | A4249_RS08315 | | cystathionine gamma-synthase | low | > 48 |
| Sinorhizobium meliloti 1021 | 0.34 | SMc01843 | | 5,10-methylenetetrahydrofolate reductase | 0.45 | SMc02217 | | O-succinylhomoserine sulfhydrylase | 0.98 | 7 |
| Rhodopseudomonas palustris CGA009 | 0.34 | TX73_019175 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.48 | TX73_024775 | | O-succinylhomoserine sulfhydrylase | 0.57 | 5 |
| Dinoroseobacter shibae DFL-12 | 0.30 | Dshi_2080 | | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.49 | Dshi_2410 | | O-succinylhomoserine sulfhydrylase (RefSeq) | — | — |
| Fusobacterium nucleatum SB010 | 0.30 | HUW76_02285 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.42 | HUW76_08240 | | methionine gamma-lyase | low | > 35 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.24 | Echvi_3637 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.48 | Echvi_2283 | | Cystathionine beta-lyases/cystathionine gamma-synthases | 0.93 | 10 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.22 | CA265_RS23445 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.46 | CA265_RS13080 | | O-succinylhomoserine sulfhydrylase | 0.97 | 7 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.21 | CA264_16780 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.45 | CA264_02530 | | O-succinylhomoserine sulfhydrylase | low | > 74 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.20 | ABZR88_RS20935 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.31 | ABZR88_RS06685 | | cystathionine gamma-synthase | low | > 71 |
Not shown: 19 genomes with orthologs for BPHYT_RS18705 only; 1 genomes with orthologs for BPHYT_RS33835 only