Conservation of cofitness between Atu1542 and Atu2808 in Agrobacterium fabrum C58

58 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu1542 Bifunctional adenosylcobalamin biosynthesis protein cobP 1.0 Atu2808 cobyric acid synthase 0.74 3
Sinorhizobium meliloti 1021 0.61 SMc04305 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.52 SMc04309 cobyric acid synthase — —
Rhizobium sp. OAE497 0.60 ABIE40_RS11165 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.54 ABIE40_RS11175 cobyric acid synthase 0.87 10
Azospirillum brasilense Sp245 0.54 AZOBR_RS09835 adenosylcobinamide kinase 0.59 AZOBR_RS09845 cobyric acid synthase — —
Sphingomonas koreensis DSMZ 15582 0.51 Ga0059261_0631 adenosylcobinamide kinase (EC 2.7.1.156)/adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.54 Ga0059261_0630 adenosylcobyric acid synthase (glutamine-hydrolysing) (EC 6.3.5.10) low > 68
Azospirillum sp. SherDot2 0.51 MPMX19_01023 Bifunctional adenosylcobalamin biosynthesis protein CobP 0.56 MPMX19_01025 Cobyric acid synthase — —
Vibrio cholerae E7946 ATCC 55056 0.50 CSW01_06270 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.43 CSW01_17810 cobyric acid synthase CobQ low > 62
Magnetospirillum magneticum AMB-1 0.49 AMB_RS22385 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.53 AMB_RS01485 cobyric acid synthase — —
Bosea sp. OAE506 0.47 ABIE41_RS01770 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.51 ABIE41_RS03845 cobyric acid synthase — —
Phaeobacter inhibens DSM 17395 0.45 PGA1_c26670 bifunctional adenosylcobalamin biosynthesis protein CobP 0.52 PGA1_c24000 cobyric acid synthase CobQ — —
Dinoroseobacter shibae DFL-12 0.43 Dshi_2979 Adenosylcobinamide-phosphateguanylyltransferase (RefSeq) 0.49 Dshi_2096 cobyric acid synthase CobQ (RefSeq) — —
Rhodopseudomonas palustris CGA009 0.43 TX73_003695 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.52 TX73_003715 cobyric acid synthase — —
Rhodanobacter sp. FW510-T8 0.43 OKGIIK_05505 cobU bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.40 OKGIIK_05500 cobyric acid synthase low > 52
Pseudomonas sp. S08-1 0.43 OH686_04960 Adenosylcobinamide kinase / Adenosylcobinamide-phosphate guanylyltransferase 0.41 OH686_04965 cobyric acid synthase CobQ 0.43 60
Rhodospirillum rubrum S1H 0.42 Rru_A0670 Cobalbumin biosynthesis enzyme (NCBI) 0.51 Rru_A3549 Cobyric acid synthase CobQ (NCBI) 0.71 10
Paraburkholderia sabiae LMG 24235 0.42 QEN71_RS25100 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.41 QEN71_RS25095 cobyric acid synthase low > 153
Burkholderia phytofirmans PsJN 0.42 BPHYT_RS04895 adenosylcobinamide kinase 0.39 BPHYT_RS04900 cobyric acid synthase low > 109
Shewanella amazonensis SB2B 0.42 Sama_0764 cobinamide kinase/cobinamide phosphate guanylyltransferase (RefSeq) 0.38 Sama_0765 cobyric acid synthase (RefSeq) low > 62
Lysobacter sp. OAE881 0.42 ABIE51_RS04970 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.41 ABIE51_RS04965 cobyric acid synthase low > 62
Pseudomonas stutzeri RCH2 0.42 Psest_3007 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase 0.40 Psest_3008 cobyric acid synthase CobQ low > 67
Pseudomonas fluorescens FW300-N2E3 0.41 AO353_02610 adenosylcobinamide kinase 0.39 AO353_02615 cobyric acid synthase 0.85 4
Dyella japonica UNC79MFTsu3.2 0.41 ABZR86_RS10895 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.40 ABZR86_RS10900 cobyric acid synthase low > 74
Pseudomonas fluorescens FW300-N2E2 0.41 Pf6N2E2_5743 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.40 Pf6N2E2_5742 Cobyric acid synthase (EC 6.3.5.10) 0.62 4
Pseudomonas fluorescens GW456-L13 0.41 PfGW456L13_4237 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.39 PfGW456L13_4238 Cobyric acid synthase (EC 6.3.5.10) 0.62 7
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_3712 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.40 Pf1N1B4_3711 Cobyric acid synthase (EC 6.3.5.10) 0.69 4
Pseudomonas syringae pv. syringae B728a 0.41 Psyr_3675 adenosylcobinamide kinase 0.40 Psyr_3676 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.57 1
Pseudomonas syringae pv. syringae B728a ΔmexB 0.41 Psyr_3675 adenosylcobinamide kinase 0.40 Psyr_3676 adenosylcobyric acid synthase (glutamine-hydrolysing) low > 86
Pseudomonas fluorescens FW300-N2C3 0.40 AO356_19165 adenosylcobinamide kinase 0.38 AO356_19160 cobyric acid synthase 0.51 10
Pseudomonas simiae WCS417 0.40 PS417_20035 adenosylcobinamide kinase 0.39 PS417_20040 cobyric acid synthase 0.47 8
Pseudomonas sp. RS175 0.40 PFR28_03203 Bifunctional adenosylcobalamin biosynthesis protein CobP 0.39 PFR28_03204 Cobyric acid synthase 0.71 4
Dechlorosoma suillum PS 0.40 Dsui_0473 adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase 0.38 Dsui_0542 cobyric acid synthase CobQ low > 51
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.39 GFF3967 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.35 GFF3966 Cobyric acid synthase (EC 6.3.5.10) low > 78
Pseudomonas putida KT2440 0.39 PP_1678 bifunctional cobinamide-P guanylyltransferase - adenosylcobinamide kinase 0.42 PP_1677 Adenosyl-cobyric acid synthase 0.56 9
Paraburkholderia bryophila 376MFSha3.1 0.39 H281DRAFT_00145 adenosylcobinamide kinase /adenosylcobinamide-phosphate guanylyltransferase 0.40 H281DRAFT_00146 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.91 3
Phocaeicola vulgatus CL09T03C04 0.39 HMPREF1058_RS01270 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.32 HMPREF1058_RS01395 cobyric acid synthase 0.80 9
Phocaeicola dorei CL03T12C01 0.39 ABI39_RS16460 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.32 ABI39_RS15660 cobyric acid synthase 0.95 2
Paraburkholderia graminis OAS925 0.38 ABIE53_001254 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.39 ABIE53_001255 adenosylcobyric acid synthase 0.97 1
Hydrogenophaga sp. GW460-11-11-14-LB1 0.38 GFF3979 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.30 GFF3998 Cobyric acid synthase (EC 6.3.5.10) — —
Pseudomonas fluorescens SBW25 0.37 PFLU_RS22000 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.38 PFLU_RS22005 cobyric acid synthase 0.85 2
Pseudomonas fluorescens SBW25-INTG 0.37 PFLU_RS22000 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.38 PFLU_RS22005 cobyric acid synthase 0.77 1
Desulfovibrio vulgaris Hildenborough JW710 0.37 DVU1007 cobU cobinamide kinase/cobinamide phosphate guanylyltransferase (TIGR) 0.33 DVU0816 cobQ cobyric acid synthase CobQ (TIGR) 0.95 1
Variovorax sp. SCN45 0.37 GFF448 Adenosylcobinamide kinase (EC 2.7.1.156) / Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.30 GFF426 Cobyric acid synthase (EC 6.3.5.10) low > 127
Ralstonia solanacearum IBSBF1503 0.37 RALBFv3_RS04450 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.40 RALBFv3_RS04445 cobyric acid synthase 0.36 18
Ralstonia solanacearum UW163 0.37 UW163_RS09220 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.40 UW163_RS09225 cobyric acid synthase — —
Klebsiella michiganensis M5al 0.37 BWI76_RS23005 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.34 BWI76_RS23010 cobyric acid synthase CobQ low > 92
Ralstonia solanacearum PSI07 0.37 RPSI07_RS12920 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.39 RPSI07_RS12925 cobyric acid synthase low > 81
Ralstonia solanacearum GMI1000 0.37 RS_RS12005 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.40 RS_RS12000 cobyric acid synthase low > 80
Shewanella loihica PV-4 0.36 Shew_0716 cobalbumin biosynthesis enzyme (RefSeq) 0.40 Shew_0717 cobyric acid synthase (RefSeq) low > 60
Parabacteroides merdae CL09T00C40 0.35 HMPREF1078_RS17685 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.31 HMPREF1078_RS00930 cobyric acid synthase 0.52 55
Acidovorax sp. GW101-3H11 0.35 Ac3H11_987 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.28 Ac3H11_999 Cobyric acid synthase (EC 6.3.5.10) low > 79
Shewanella oneidensis MR-1 0.35 SO1037 cobU cobinamide kinase/cobinamide phosphate guanylyltransferase (NCBI ptt file) 0.39 SO1038 cobQ cobyric acid synthase CobQ (NCBI ptt file) 0.63 1
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS00045 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.40 ABZR87_RS00040 cobyric acid synthase low > 80
Herbaspirillum seropedicae SmR1 0.35 HSERO_RS13245 adenosylcobinamide kinase 0.38 HSERO_RS13230 cobyric acid synthase — —
Shewanella sp. ANA-3 0.35 Shewana3_3276 adenosylcobinamide kinase (RefSeq) 0.38 Shewana3_3275 cobyric acid synthase (RefSeq) low > 73
Variovorax sp. OAS795 0.34 ABID97_RS17415 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.29 ABID97_RS17340 cobyric acid synthase — —
Fusobacterium nucleatum SB010 0.32 HUW76_05615 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.33 HUW76_05230 cobyric acid synthase — —
Desulfovibrio vulgaris Miyazaki F 0.31 DvMF_3046 cobalbumin biosynthesis protein (RefSeq) 0.29 DvMF_2864 cobyric acid synthase (RefSeq) — —
Mycobacterium tuberculosis H37Rv 0.28 Rv0254c Probable bifunctional cobalamin biosynthesis protein CobU: cobinamide kinase + cobinamide phosphate guanylyltransferase 0.33 Rv0255c Probable cobyric acid synthase CobQ1 — —
Synechococcus elongatus PCC 7942 0.26 Synpcc7942_0990 cobU adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.34 Synpcc7942_0211 cobQ cobyric acid synthase — —

Not shown: 18 genomes with orthologs for Atu1542 only; 5 genomes with orthologs for Atu2808 only