Conservation of cofitness between Atu2808 and Atu1542 in Agrobacterium fabrum C58

58 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu2808 cobyric acid synthase 1.0 Atu1542 Bifunctional adenosylcobalamin biosynthesis protein cobP 0.74 7
Azospirillum brasilense Sp245 0.59 AZOBR_RS09845 cobyric acid synthase 0.54 AZOBR_RS09835 adenosylcobinamide kinase — —
Azospirillum sp. SherDot2 0.56 MPMX19_01025 Cobyric acid synthase 0.51 MPMX19_01023 Bifunctional adenosylcobalamin biosynthesis protein CobP — —
Rhizobium sp. OAE497 0.54 ABIE40_RS11175 cobyric acid synthase 0.60 ABIE40_RS11165 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.87 59
Sphingomonas koreensis DSMZ 15582 0.54 Ga0059261_0630 adenosylcobyric acid synthase (glutamine-hydrolysing) (EC 6.3.5.10) 0.51 Ga0059261_0631 adenosylcobinamide kinase (EC 2.7.1.156)/adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) low > 68
Magnetospirillum magneticum AMB-1 0.53 AMB_RS01485 cobyric acid synthase 0.49 AMB_RS22385 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase — —
Sinorhizobium meliloti 1021 0.52 SMc04309 cobyric acid synthase 0.61 SMc04305 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase — —
Rhodopseudomonas palustris CGA009 0.52 TX73_003715 cobyric acid synthase 0.43 TX73_003695 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase — —
Phaeobacter inhibens DSM 17395 0.52 PGA1_c24000 cobyric acid synthase CobQ 0.45 PGA1_c26670 bifunctional adenosylcobalamin biosynthesis protein CobP — —
Rhodospirillum rubrum S1H 0.51 Rru_A3549 Cobyric acid synthase CobQ (NCBI) 0.42 Rru_A0670 Cobalbumin biosynthesis enzyme (NCBI) 0.71 22
Bosea sp. OAE506 0.51 ABIE41_RS03845 cobyric acid synthase 0.47 ABIE41_RS01770 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase — —
Dinoroseobacter shibae DFL-12 0.49 Dshi_2096 cobyric acid synthase CobQ (RefSeq) 0.43 Dshi_2979 Adenosylcobinamide-phosphateguanylyltransferase (RefSeq) — —
Vibrio cholerae E7946 ATCC 55056 0.43 CSW01_17810 cobyric acid synthase CobQ 0.50 CSW01_06270 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase low > 62
Pseudomonas putida KT2440 0.42 PP_1677 Adenosyl-cobyric acid synthase 0.39 PP_1678 bifunctional cobinamide-P guanylyltransferase - adenosylcobinamide kinase 0.56 14
Lysobacter sp. OAE881 0.41 ABIE51_RS04965 cobyric acid synthase 0.42 ABIE51_RS04970 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase low > 62
Pseudomonas sp. S08-1 0.41 OH686_04965 cobyric acid synthase CobQ 0.43 OH686_04960 Adenosylcobinamide kinase / Adenosylcobinamide-phosphate guanylyltransferase low > 80
Paraburkholderia sabiae LMG 24235 0.41 QEN71_RS25095 cobyric acid synthase 0.42 QEN71_RS25100 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase low > 153
Ralstonia sp. UNC404CL21Col 0.40 ABZR87_RS00040 cobyric acid synthase 0.35 ABZR87_RS00045 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase low > 80
Rhodanobacter sp. FW510-T8 0.40 OKGIIK_05500 cobyric acid synthase 0.43 OKGIIK_05505 cobU bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase low > 52
Pseudomonas stutzeri RCH2 0.40 Psest_3008 cobyric acid synthase CobQ 0.42 Psest_3007 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase low > 67
Dyella japonica UNC79MFTsu3.2 0.40 ABZR86_RS10900 cobyric acid synthase 0.41 ABZR86_RS10895 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase low > 74
Pseudomonas fluorescens FW300-N1B4 0.40 Pf1N1B4_3711 Cobyric acid synthase (EC 6.3.5.10) 0.41 Pf1N1B4_3712 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.69 4
Pseudomonas syringae pv. syringae B728a ΔmexB 0.40 Psyr_3676 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.41 Psyr_3675 adenosylcobinamide kinase low > 86
Pseudomonas syringae pv. syringae B728a 0.40 Psyr_3676 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.41 Psyr_3675 adenosylcobinamide kinase 0.57 2
Paraburkholderia bryophila 376MFSha3.1 0.40 H281DRAFT_00146 adenosylcobyric acid synthase (glutamine-hydrolysing) 0.39 H281DRAFT_00145 adenosylcobinamide kinase /adenosylcobinamide-phosphate guanylyltransferase 0.91 6
Ralstonia solanacearum UW163 0.40 UW163_RS09225 cobyric acid synthase 0.37 UW163_RS09220 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase — —
Ralstonia solanacearum GMI1000 0.40 RS_RS12000 cobyric acid synthase 0.37 RS_RS12005 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase low > 80
Ralstonia solanacearum IBSBF1503 0.40 RALBFv3_RS04445 cobyric acid synthase 0.37 RALBFv3_RS04450 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.36 38
Shewanella loihica PV-4 0.40 Shew_0717 cobyric acid synthase (RefSeq) 0.36 Shew_0716 cobalbumin biosynthesis enzyme (RefSeq) low > 60
Pseudomonas fluorescens FW300-N2E2 0.40 Pf6N2E2_5742 Cobyric acid synthase (EC 6.3.5.10) 0.41 Pf6N2E2_5743 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.62 8
Ralstonia solanacearum PSI07 0.39 RPSI07_RS12925 cobyric acid synthase 0.37 RPSI07_RS12920 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase low > 81
Pseudomonas fluorescens GW456-L13 0.39 PfGW456L13_4238 Cobyric acid synthase (EC 6.3.5.10) 0.41 PfGW456L13_4237 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) 0.62 3
Paraburkholderia graminis OAS925 0.39 ABIE53_001255 adenosylcobyric acid synthase 0.38 ABIE53_001254 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.97 3
Burkholderia phytofirmans PsJN 0.39 BPHYT_RS04900 cobyric acid synthase 0.42 BPHYT_RS04895 adenosylcobinamide kinase low > 109
Pseudomonas fluorescens FW300-N2E3 0.39 AO353_02615 cobyric acid synthase 0.41 AO353_02610 adenosylcobinamide kinase 0.85 3
Shewanella oneidensis MR-1 0.39 SO1038 cobQ cobyric acid synthase CobQ (NCBI ptt file) 0.35 SO1037 cobU cobinamide kinase/cobinamide phosphate guanylyltransferase (NCBI ptt file) low > 76
Pseudomonas simiae WCS417 0.39 PS417_20040 cobyric acid synthase 0.40 PS417_20035 adenosylcobinamide kinase 0.47 5
Pseudomonas sp. RS175 0.39 PFR28_03204 Cobyric acid synthase 0.40 PFR28_03203 Bifunctional adenosylcobalamin biosynthesis protein CobP 0.71 7
Pseudomonas fluorescens SBW25-INTG 0.38 PFLU_RS22005 cobyric acid synthase 0.37 PFLU_RS22000 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.77 9
Herbaspirillum seropedicae SmR1 0.38 HSERO_RS13230 cobyric acid synthase 0.35 HSERO_RS13245 adenosylcobinamide kinase — —
Pseudomonas fluorescens SBW25 0.38 PFLU_RS22005 cobyric acid synthase 0.37 PFLU_RS22000 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.85 7
Pseudomonas fluorescens FW300-N2C3 0.38 AO356_19160 cobyric acid synthase 0.40 AO356_19165 adenosylcobinamide kinase 0.51 19
Shewanella sp. ANA-3 0.38 Shewana3_3275 cobyric acid synthase (RefSeq) 0.35 Shewana3_3276 adenosylcobinamide kinase (RefSeq) low > 73
Shewanella amazonensis SB2B 0.38 Sama_0765 cobyric acid synthase (RefSeq) 0.42 Sama_0764 cobinamide kinase/cobinamide phosphate guanylyltransferase (RefSeq) low > 62
Dechlorosoma suillum PS 0.38 Dsui_0542 cobyric acid synthase CobQ 0.40 Dsui_0473 adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase low > 51
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.35 GFF3966 Cobyric acid synthase (EC 6.3.5.10) 0.39 GFF3967 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) low > 78
Klebsiella michiganensis M5al 0.34 BWI76_RS23010 cobyric acid synthase CobQ 0.37 BWI76_RS23005 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase low > 92
Synechococcus elongatus PCC 7942 0.34 Synpcc7942_0211 cobQ cobyric acid synthase 0.26 Synpcc7942_0990 cobU adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase — —
Mycobacterium tuberculosis H37Rv 0.33 Rv0255c Probable cobyric acid synthase CobQ1 0.28 Rv0254c Probable bifunctional cobalamin biosynthesis protein CobU: cobinamide kinase + cobinamide phosphate guanylyltransferase — —
Fusobacterium nucleatum SB010 0.33 HUW76_05230 cobyric acid synthase 0.32 HUW76_05615 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase — —
Desulfovibrio vulgaris Hildenborough JW710 0.33 DVU0816 cobQ cobyric acid synthase CobQ (TIGR) 0.37 DVU1007 cobU cobinamide kinase/cobinamide phosphate guanylyltransferase (TIGR) 0.95 6
Phocaeicola vulgatus CL09T03C04 0.32 HMPREF1058_RS01395 cobyric acid synthase 0.39 HMPREF1058_RS01270 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.80 13
Phocaeicola dorei CL03T12C01 0.32 ABI39_RS15660 cobyric acid synthase 0.39 ABI39_RS16460 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.95 4
Parabacteroides merdae CL09T00C40 0.31 HMPREF1078_RS00930 cobyric acid synthase 0.35 HMPREF1078_RS17685 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 0.52 45
Hydrogenophaga sp. GW460-11-11-14-LB1 0.30 GFF3998 Cobyric acid synthase (EC 6.3.5.10) 0.38 GFF3979 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) — —
Variovorax sp. SCN45 0.30 GFF426 Cobyric acid synthase (EC 6.3.5.10) 0.37 GFF448 Adenosylcobinamide kinase (EC 2.7.1.156) / Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) low > 127
Variovorax sp. OAS795 0.29 ABID97_RS17340 cobyric acid synthase 0.34 ABID97_RS17415 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase — —
Desulfovibrio vulgaris Miyazaki F 0.29 DvMF_2864 cobyric acid synthase (RefSeq) 0.31 DvMF_3046 cobalbumin biosynthesis protein (RefSeq) — —
Acidovorax sp. GW101-3H11 0.28 Ac3H11_999 Cobyric acid synthase (EC 6.3.5.10) 0.35 Ac3H11_987 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) low > 79

Not shown: 5 genomes with orthologs for Atu2808 only; 18 genomes with orthologs for Atu1542 only