| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Shewanella oneidensis MR-1 | 1.0 | SO1894 | | acetyl-CoA carboxylase, biotin carboxylase, putative (NCBI ptt file) | 1.0 | SO1895 | | enoyl-CoA hydratase/isomerase family protein (NCBI ptt file) | 0.81 | 2 |
| Shewanella sp. ANA-3 | 0.93 | Shewana3_1669 | | 3-methylcrotonoyl-CoA carboxylase, alpha subunit (RefSeq) | 0.93 | Shewana3_1670 | | methylglutaconyl-CoA hydratase (RefSeq) | 0.80 | 3 |
| Shewanella loihica PV-4 | 0.76 | Shew_2573 | | carbamoyl-phosphate synthase L chain, ATP-binding (RefSeq) | 0.73 | Shew_2572 | | enoyl-CoA hydratase/isomerase (RefSeq) | 0.72 | 5 |
| Shewanella amazonensis SB2B | 0.68 | Sama_1359 | | 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data) | 0.60 | Sama_1360 | | enoyl-CoA hydratase/isomerase (RefSeq) | 0.43 | 4 |
| Marinobacter adhaerens HP15 | 0.50 | HP15_4179 | | methylcrotonyl-CoA carboxylase, alpha subunit | 0.39 | HP15_1003 | | enoyl-CoA hydratase/isomerase | — | — |
| Alteromonas macleodii MIT1002 | 0.48 | MIT1002_01666 | | Acetyl-/propionyl-coenzyme A carboxylase alpha chain | 0.41 | MIT1002_01667 | | putative enoyl-CoA hydratase echA8 | 0.76 | 24 |
| Kangiella aquimarina DSM 16071 | 0.48 | B158DRAFT_2507 | | Acetyl/propionyl-CoA carboxylase, alpha subunit | 0.43 | B158DRAFT_2508 | | Enoyl-CoA hydratase/carnithine racemase | — | — |
| Azospirillum sp. SherDot2 | 0.45 | MPMX19_03940 | | Acetyl-/propionyl-coenzyme A carboxylase alpha chain | 0.40 | MPMX19_03939 | | Enoyl-CoA-hydratase | low | > 112 |
| Azospirillum brasilense Sp245 | 0.45 | AZOBR_RS22285 | | 3-methylcrotonyl-CoA carboxylase subunit alpha | 0.37 | AZOBR_RS22290 | | enoyl-CoA hydratase | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.44 | RALBFv3_RS10460 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.37 | RALBFv3_RS10470 | | enoyl-CoA hydratase | low | > 76 |
| Ralstonia solanacearum UW163 | 0.44 | UW163_RS03120 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.37 | UW163_RS03110 | | enoyl-CoA hydratase | — | — |
| Ralstonia solanacearum PSI07 | 0.44 | RPSI07_RS22860 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.37 | RPSI07_RS22845 | | enoyl-CoA hydratase | low | > 81 |
| Pseudomonas segetis P6 | 0.44 | MPMX49_02359 | | Acetyl-/propionyl-coenzyme A carboxylase alpha chain | 0.39 | MPMX49_02360 | | 1,4-dihydroxy-2-naphthoyl-CoA synthase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.43 | RR42_RS26895 | | 3-methylcrotonyl-CoA carboxylase | 0.38 | RR42_RS26900 | | enoyl-CoA hydratase | 0.69 | 5 |
| Magnetospirillum magneticum AMB-1 | 0.43 | AMB_RS03465 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.40 | AMB_RS03470 | | enoyl-CoA hydratase | low | > 64 |
| Ralstonia sp. UNC404CL21Col | 0.43 | ABZR87_RS06260 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.39 | ABZR87_RS06270 | | enoyl-CoA hydratase/isomerase family protein | 0.61 | 2 |
| Ralstonia solanacearum GMI1000 | 0.43 | RS_RS01300 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.37 | RS_RS01310 | | enoyl-CoA hydratase | low | > 80 |
| Pseudomonas fluorescens FW300-N1B4 | 0.43 | Pf1N1B4_3984 | | 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data) | 0.38 | Pf1N1B4_3985 | | Methylglutaconyl-CoA hydratase (EC 4.2.1.18) | 0.42 | 5 |
| Pseudomonas fluorescens GW456-L13 | 0.43 | PfGW456L13_2588 | | Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) | 0.39 | PfGW456L13_2589 | | Methylglutaconyl-CoA hydratase (EC 4.2.1.18) | 0.53 | 24 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.43 | Psyr_2467 | | 3-methylcrotonoyl-CoA carboxylase, alpha subunit | 0.39 | Psyr_2468 | | Enoyl-CoA hydratase/isomerase | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.43 | Psyr_2467 | | 3-methylcrotonoyl-CoA carboxylase, alpha subunit | 0.39 | Psyr_2468 | | Enoyl-CoA hydratase/isomerase | low | > 86 |
| Pseudomonas stutzeri RCH2 | 0.43 | Psest_1080 | | Acetyl/propionyl-CoA carboxylase, alpha subunit | 0.41 | Psest_1082 | | Enoyl-CoA hydratase/carnithine racemase | 0.68 | 3 |
| Pseudomonas simiae WCS417 | 0.43 | PS417_17030 | | 3-methylcrotonyl-CoA carboxylase | 0.38 | PS417_17025 | | gamma-carboxygeranoyl-CoA hydratase | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.43 | AO353_20335 | | 3-methylcrotonyl-CoA carboxylase | 0.39 | AO353_20340 | | gamma-carboxygeranoyl-CoA hydratase | 0.37 | 10 |
| Acinetobacter baumannii LAC-4 | 0.43 | RR41_RS11115 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.35 | RR41_RS11120 | | enoyl-CoA hydratase/isomerase family protein | low | > 55 |
| Pseudomonas fluorescens FW300-N2E2 | 0.43 | Pf6N2E2_2194 | | 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data) | 0.40 | Pf6N2E2_2193 | | Methylglutaconyl-CoA hydratase (EC 4.2.1.18) (from data) | 0.75 | 3 |
| Pseudomonas aeruginosa PA14 | 0.43 | IKLFDK_09835 | | methylcrotonyl-CoA carboxylase subunit alpha | 0.39 | IKLFDK_09840 | | gamma-carboxygeranoyl-CoA hydratase | low | > 98 |
| Dechlorosoma suillum PS | 0.43 | Dsui_0982 | | acetyl/propionyl-CoA carboxylase, alpha subunit | 0.39 | Dsui_0981 | | enoyl-CoA hydratase/carnithine racemase | low | > 51 |
| Agrobacterium fabrum C58 | 0.43 | Atu3479 | | 3-methylcrotonyl-CoA carboxylase subunit alpha | 0.17 | Atu3481 | | enoyl-CoA hydratase | 0.55 | 2 |
| Pseudomonas sp. DMC3 | 0.43 | GFF1471 | | Acetyl-/propionyl-coenzyme A carboxylase alpha chain | 0.40 | GFF1472 | | 1,4-dihydroxy-2-naphthoyl-CoA synthase | low | > 89 |
| Herbaspirillum seropedicae SmR1 | 0.43 | HSERO_RS23460 | | 3-methylcrotonyl-CoA carboxylase subunit alpha | 0.37 | HSERO_RS15435 | | enoyl-CoA hydratase | 0.64 | 10 |
| Pseudomonas aeruginosa PUPa3 | 0.43 | DQ20_RS38565 | liuD;inference=COORDINATES | methylcrotonyl-CoA carboxylase subunit alpha | 0.39 | DQ20_RS38570 | | gamma-carboxygeranoyl-CoA hydratase | 0.46 | 3 |
| Pseudomonas fluorescens FW300-N2C3 | 0.43 | AO356_01595 | | 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data) | 0.40 | AO356_01590 | | Methylglutaconyl-CoA hydratase (EC 4.2.1.18) (from data) | 0.68 | 3 |
| Pseudomonas sp. SVBP6 | 0.43 | COO64_RS24740 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.38 | COO64_RS24745 | | gamma-carboxygeranoyl-CoA hydratase | low | > 93 |
| Pseudomonas putida KT2440 | 0.43 | PP_4067 | | methylcrotonyl-CoA carboxylase biotin-containing subunit alpha | 0.39 | PP_4066 | | methylglutaconyl-CoA hydratase | 0.77 | 3 |
| Paraburkholderia sabiae LMG 24235 | 0.42 | QEN71_RS12855 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.37 | QEN71_RS12860 | | enoyl-CoA hydratase/isomerase family protein | 0.97 | 2 |
| Pseudomonas sp. S08-1 | 0.42 | OH686_00840 | | Methylcrotonyl-CoA carboxylase biotin-containing subunit | 0.41 | OH686_00845 | | Methylglutaconyl-CoA hydratase | low | > 80 |
| Pseudomonas sp. RS175 | 0.42 | PFR28_01257 | | Acetyl-/propionyl-coenzyme A carboxylase alpha chain | 0.39 | PFR28_01258 | | 1,4-dihydroxy-2-naphthoyl-CoA synthase | 0.68 | 4 |
| Pseudomonas fluorescens SBW25-INTG | 0.42 | PFLU_RS18980 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.37 | PFLU_RS18975 | | gamma-carboxygeranoyl-CoA hydratase | 0.76 | 3 |
| Pseudomonas sp. BP01 | 0.42 | JOY50_RS06805 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.40 | JOY50_RS06800 | | gamma-carboxygeranoyl-CoA hydratase | low | > 84 |
| Pseudomonas fluorescens SBW25 | 0.42 | PFLU_RS18980 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.37 | PFLU_RS18975 | | gamma-carboxygeranoyl-CoA hydratase | low | > 109 |
| Pseudomonas aeruginosa MRSN321 | 0.42 | DY961_RS16245 | liuD;inference=COORDINATES | methylcrotonyl-CoA carboxylase subunit alpha | 0.39 | DY961_RS16250 | | gamma-carboxygeranoyl-CoA hydratase | low | > 100 |
| Rhodanobacter sp000427505 FW510-R12 | 0.42 | LRK53_RS07685 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.31 | LRK53_RS07695 | | enoyl-CoA hydratase-related protein | low | > 59 |
| Pseudomonas orientalis W4I3 | 0.42 | QF045_RS18710 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.38 | QF045_RS18705 | | gamma-carboxygeranoyl-CoA hydratase | low | > 93 |
| Burkholderia phytofirmans PsJN | 0.42 | BPHYT_RS23275 | | 3-methylcrotonyl-CoA carboxylase subunit alpha | 0.37 | BPHYT_RS23270 | | enoyl-CoA hydratase | low | > 109 |
| Xanthobacter sp. DMC5 | 0.42 | GFF3791 | | Acetyl-/propionyl-coenzyme A carboxylase alpha chain | 0.38 | GFF3792 | | Enoyl-CoA-hydratase | — | — |
| Lysobacter sp. OAE881 | 0.42 | ABIE51_RS13200 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.38 | ABIE51_RS13190 | | enoyl-CoA hydratase-related protein | — | — |
| Pseudomonas lactucae CFBP13502 | 0.41 | GEMAOFIL_03716 | | Acetyl-/propionyl-coenzyme A carboxylase alpha chain | 0.37 | GEMAOFIL_03715 | | 1,4-dihydroxy-2-naphthoyl-CoA synthase | low | > 96 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.41 | Xcc-8004.318.1 | | Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) | 0.28 | Xcc-8004.2922.1 | | Methylglutaconyl-CoA hydratase (EC 4.2.1.18) | 0.68 | 10 |
| Acinetobacter radioresistens SK82 | 0.41 | MPMX26_00629 | | Acetyl-/propionyl-coenzyme A carboxylase alpha chain | 0.32 | MPMX26_00630 | | 2,3-dehydroadipyl-CoA hydratase | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.41 | H281DRAFT_01343 | | 3-methylcrotonoyl-CoA carboxylase, alpha subunit | 0.37 | H281DRAFT_01344 | | methylglutaconyl-CoA hydratase | — | — |
| Acidovorax sp. GW101-3H11 | 0.41 | Ac3H11_3016 | | Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) | 0.38 | Ac3H11_3014 | | Methylglutaconyl-CoA hydratase (EC 4.2.1.18) | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.41 | LRK54_RS02280 | | ATP-grasp domain-containing protein | 0.31 | LRK54_RS02275 | | enoyl-CoA hydratase-related protein | low | > 59 |
| Rhodanobacter denitrificans MT42 | 0.41 | LRK55_RS02035 | | biotin carboxylase N-terminal domain-containing protein | 0.31 | LRK55_RS02030 | | enoyl-CoA hydratase-related protein | — | — |
| Paraburkholderia graminis OAS925 | 0.41 | ABIE53_005468 | | 3-methylcrotonyl-CoA carboxylase alpha subunit | 0.37 | ABIE53_005467 | | methylglutaconyl-CoA hydratase | low | > 113 |
| Rhodanobacter sp. FW510-T8 | 0.41 | OKGIIK_09335 | | 3-methylcrotonyl-CoA carboxylase | 0.31 | OKGIIK_09325 | | Enoyl-CoA hydratase | low | > 53 |
| Dyella japonica UNC79MFTsu3.2 | 0.40 | ABZR86_RS20625 | | biotin carboxylase N-terminal domain-containing protein | 0.34 | ABZR86_RS20610 | | enoyl-CoA hydratase-related protein | — | — |
| Phaeobacter inhibens DSM 17395 | 0.39 | PGA1_c10330 | | methylcrotonoyl-CoA carboxylase subunit alpha | 0.27 | PGA1_c10360 | | putative enoyl-CoA hydratase | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.39 | GFF1711 | | Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) | 0.36 | GFF1713 | | Methylglutaconyl-CoA hydratase (EC 4.2.1.18) | 0.71 | 47 |
| Variovorax sp. OAS795 | 0.38 | ABID97_RS25115 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.37 | ABID97_RS25125 | | enoyl-CoA hydratase/isomerase family protein | 0.95 | 2 |
| Variovorax sp. SCN45 | 0.38 | GFF2013 | | Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) | 0.36 | GFF2010 | | Methylglutaconyl-CoA hydratase (EC 4.2.1.18) | low | > 127 |
| Sinorhizobium meliloti 1021 | 0.38 | SM_b21124 | | 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data) | 0.29 | SM_b21126 | | 3-methylglutaconyl-CoA hydratase (EC 4.2.1.18) (from data) | 0.74 | 7 |
| Rhodopseudomonas palustris CGA009 | 0.37 | TX73_013120 | | acetyl-CoA carboxylase biotin carboxylase subunit | 0.17 | TX73_011065 | | enoyl-CoA hydratase/isomerase family protein | low | > 86 |
| Bosea sp. OAE506 | 0.36 | ABIE41_RS14850 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.15 | ABIE41_RS10405 | | enoyl-CoA hydratase/isomerase family protein | low | > 77 |
| Rhodospirillum rubrum S1H | 0.36 | Rru_A1941 | | acyl-CoA carboxylase alpha chain (NCBI) | 0.39 | Rru_A1942 | | Enoyl-CoA hydratase/isomerase (NCBI) | low | > 58 |
| Rhizobium sp. OAE497 | 0.36 | ABIE40_RS20775 | | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | 0.28 | ABIE40_RS20765 | | crotonase/enoyl-CoA hydratase family protein | 0.80 | 6 |
| Sphingobium sp. HT1-2 | 0.36 | GFF4876 | | Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) | 0.17 | GFF4877 | | Isohexenylglutaconyl-CoA hydratase (EC 4.2.1.57) | low | > 95 |
| Caulobacter crescentus NA1000 Δfur | 0.36 | CCNA_02250 | | methylcrotonyl-CoA carboxylase biotin-containing subunit | 0.29 | CCNA_02251 | | methylglutaconyl-CoA hydratase | low | > 67 |
| Caulobacter crescentus NA1000 | 0.36 | CCNA_02250 | | methylcrotonyl-CoA carboxylase biotin-containing subunit | 0.29 | CCNA_02251 | | methylglutaconyl-CoA hydratase | — | — |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.35 | A4249_RS03810 | | biotin carboxylase N-terminal domain-containing protein | 0.30 | A4249_RS03800 | | enoyl-CoA hydratase-related protein | — | — |
| Dinoroseobacter shibae DFL-12 | 0.33 | Dshi_0723 | | Propionyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.3) (from data) | 0.25 | Dshi_1304 | | Enoyl-CoA hydratase/isomerase (RefSeq) | low | > 64 |
| Mycobacterium tuberculosis H37Rv | 0.33 | Rv2501c | | Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA1: biotin carboxylase + biotin carboxyl carrier protein (BCCP) | 0.19 | Rv0971c | | Probable enoyl-CoA hydratase EchA7 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) | low | > 58 |
Not shown: 2 genomes with orthologs for SO1894 only; 13 genomes with orthologs for SO1895 only