Conservation of cofitness between b4015 and b1703 in Escherichia coli BW25113

74 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b4015 aceA isocitrate lyase (NCBI) 1.0 b1703 ydiA hypothetical protein (NCBI) 0.19 18
Escherichia coli ECOR27 1.00 NOLOHH_05410 aceA isocitrate lyase 1.00 NOLOHH_17660 ppsR posphoenolpyruvate synthetase regulatory kinase/phosphorylase PpsR — —
Escherichia coli ECOR38 1.00 HEPCGN_11905 aceA isocitrate lyase 1.00 HEPCGN_05505 ppsR posphoenolpyruvate synthetase regulatory kinase/phosphorylase PpsR low > 85
Escherichia coli BL21 1.00 ECD_03887 isocitrate lyase 1.00 ECD_01672 PEP synthase kinase and PEP synthase pyrophosphorylase — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS26870 isocitrate lyase 1.00 ECOLIN_RS09520 posphoenolpyruvate synthetase regulatory kinase/phosphorylase PpsR — —
Escherichia coli ECRC62 1.00 BNILDI_06110 aceA isocitrate lyase 1.00 BNILDI_16450 ppsR posphoenolpyruvate synthetase regulatory kinase/phosphorylase PpsR — —
Escherichia fergusonii Becca 1.00 EFB2_04595 Isocitrate lyase 1.00 EFB2_02288 Phosphoenolpyruvate synthase regulatory protein low > 86
Escherichia coli ECRC101 1.00 MCAODC_03765 aceA isocitrate lyase 1.00 MCAODC_18270 ppsR posphoenolpyruvate synthetase regulatory kinase/phosphorylase PpsR — —
Escherichia coli ECRC102 1.00 NIAGMN_11015 aceA isocitrate lyase 1.00 NIAGMN_00925 ppsR posphoenolpyruvate synthetase regulatory kinase/phosphorylase PpsR — —
Escherichia coli ECRC98 1.00 JDDGAC_16890 aceA isocitrate lyase 1.00 JDDGAC_01715 ppsR posphoenolpyruvate synthetase regulatory kinase/phosphorylase PpsR — —
Escherichia coli ECRC101 1.00 OKFHMN_13265 aceA isocitrate lyase 1.00 OKFHMN_27140 ppsR posphoenolpyruvate synthetase regulatory kinase/phosphorylase PpsR — —
Escherichia coli ECRC99 1.00 KEDOAH_14895 aceA isocitrate lyase 1.00 KEDOAH_00970 ppsR posphoenolpyruvate synthetase regulatory kinase/phosphorylase PpsR — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF1352 Isocitrate lyase (EC 4.1.3.1) 0.97 GFF3537 FIG137360: hypothetical protein low > 78
Klebsiella michiganensis M5al 0.96 BWI76_RS01665 Isocitrate lyase (EC 4.1.3.1) (from data) 0.92 BWI76_RS17070 phosphoenolpyruvate synthase regulatory protein low > 92
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4329 isocitrate lyase 0.95 EX28DRAFT_1705 Uncharacterized protein conserved in bacteria low > 76
Enterobacter sp. TBS_079 0.94 MPMX20_00232 Isocitrate lyase 0.96 MPMX20_01921 Phosphoenolpyruvate synthase regulatory protein low > 85
Pectobacterium carotovorum WPP14 0.89 HER17_RS02295 isocitrate lyase 0.81 HER17_RS08880 kinase/pyrophosphorylase low > 75
Dickeya dianthicola 67-19 0.89 HGI48_RS19145 isocitrate lyase 0.81 HGI48_RS12880 kinase/pyrophosphorylase low > 71
Dickeya dadantii 3937 0.88 DDA3937_RS19055 isocitrate lyase 0.81 DDA3937_RS12810 kinase/pyrophosphorylase low > 74
Dickeya dianthicola ME23 0.88 DZA65_RS20265 isocitrate lyase 0.81 DZA65_RS13345 kinase/pyrophosphorylase low > 75
Serratia liquefaciens MT49 0.87 IAI46_23190 isocitrate lyase 0.82 IAI46_11110 kinase/pyrophosphorylase low > 86
Rahnella sp. WP5 0.87 EX31_RS11745 isocitrate lyase 0.79 EX31_RS13940 kinase/pyrophosphorylase low > 89
Pantoea sp. MT58 0.84 IAI47_18005 isocitrate lyase 0.81 IAI47_10910 kinase/pyrophosphorylase 0.31 49
Shewanella loihica PV-4 0.83 Shew_1276 Isocitrate lyase (EC 4.1.3.1) (from data) 0.61 Shew_1548 hypothetical protein (RefSeq) low > 60
Shewanella amazonensis SB2B 0.83 Sama_2380 Isocitrate lyase (EC 4.1.3.1) (from data) 0.62 Sama_2073 hypothetical protein (RefSeq) low > 62
Shewanella oneidensis MR-1 0.82 SO1484 aceA Isocitrate lyase (EC 4.1.3.1) (from data) 0.60 SO2645 conserved hypothetical protein (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.82 Shewana3_2942 isocitrate lyase (RefSeq) 0.60 Shewana3_1735 hypothetical protein (RefSeq) low > 73
Vibrio cholerae E7946 ATCC 55056 0.80 CSW01_03830 isocitrate lyase 0.50 CSW01_19045 phosphoenolpyruvate synthase regulatory protein low > 62
Dechlorosoma suillum PS 0.75 Dsui_0011 isocitrate lyase 0.45 Dsui_2678 hypothetical protein low > 51
Variovorax sp. OAS795 0.75 ABID97_RS11115 isocitrate lyase 0.43 ABID97_RS10810 pyruvate, water dikinase regulatory protein — —
Pseudomonas fluorescens SBW25 0.74 PFLU_RS18610 isocitrate lyase 0.48 PFLU_RS22635 kinase/pyrophosphorylase low > 109
Pseudomonas fluorescens SBW25-INTG 0.74 PFLU_RS18610 isocitrate lyase 0.48 PFLU_RS22635 kinase/pyrophosphorylase low > 109
Variovorax sp. SCN45 0.74 GFF4829 Isocitrate lyase (EC 4.1.3.1) 0.42 GFF2819 Phosphoenolpyruvate synthase regulatory protein low > 127
Pseudomonas simiae WCS417 0.74 PS417_16570 isocitrate lyase 0.48 PS417_21025 PEP synthetase regulatory protein low > 88
Pseudomonas fluorescens FW300-N2E3 0.74 AO353_27735 isocitrate lyase 0.48 AO353_00875 transcriptional regulator low > 101
Hydrogenophaga sp. GW460-11-11-14-LB1 0.74 GFF4147 Isocitrate lyase (EC 4.1.3.1) 0.43 GFF3919 FIG137360: hypothetical protein — —
Pseudomonas fluorescens GW456-L13 0.74 PfGW456L13_2633 Isocitrate lyase (EC 4.1.3.1) 0.49 PfGW456L13_4113 FIG137360: hypothetical protein low > 87
Pseudomonas sp. RS175 0.74 PFR28_02625 Isocitrate lyase 0.48 PFR28_01037 Phosphoenolpyruvate synthase regulatory protein 0.42 10
Pseudomonas fluorescens FW300-N1B4 0.74 Pf1N1B4_4042 Isocitrate lyase (EC 4.1.3.1) (from data) 0.48 Pf1N1B4_3824 FIG137360: hypothetical protein low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.74 Psyr_3196 isocitrate lyase 0.47 Psyr_2089 Protein of unknown function DUF299 low > 86
Pseudomonas syringae pv. syringae B728a 0.74 Psyr_3196 isocitrate lyase 0.47 Psyr_2089 Protein of unknown function DUF299 low > 86
Pseudomonas fluorescens FW300-N2C3 0.74 AO356_22080 isocitrate lyase 0.48 AO356_02830 transcriptional regulator low > 104
Pseudomonas fluorescens FW300-N2E2 0.74 Pf6N2E2_279 Isocitrate lyase (EC 4.1.3.1) 0.48 Pf6N2E2_2391 FIG137360: hypothetical protein 0.41 16
Acidovorax sp. GW101-3H11 0.73 Ac3H11_2831 Isocitrate lyase (EC 4.1.3.1) (from data) 0.42 Ac3H11_207 FIG137360: hypothetical protein low > 79
Pseudomonas putida KT2440 0.73 PP_4116 isocitrate lyase 0.47 PP_2081 putative phosphoenolpyruvate synthase regulatory protein low > 96
Castellaniella sp019104865 MT123 0.71 ABCV34_RS06915 isocitrate lyase 0.45 ABCV34_RS04030 pyruvate, water dikinase regulatory protein — —
Paraburkholderia graminis OAS925 0.69 ABIE53_002536 isocitrate lyase 0.43 ABIE53_002487 regulator of PEP synthase PpsR (kinase-PPPase family) low > 113
Lysobacter sp. OAE881 0.69 ABIE51_RS00190 isocitrate lyase 0.40 ABIE51_RS09530 pyruvate, water dikinase regulatory protein low > 62
Paraburkholderia bryophila 376MFSha3.1 0.69 H281DRAFT_00580 isocitrate lyase 0.42 H281DRAFT_00626 hypothetical protein — —
Paraburkholderia sabiae LMG 24235 0.69 QEN71_RS06270 isocitrate lyase 0.44 QEN71_RS06500 pyruvate, water dikinase regulatory protein low > 153
Herbaspirillum seropedicae SmR1 0.69 HSERO_RS10565 isocitrate lyase 0.45 HSERO_RS10960 PEP synthetase regulatory protein low > 78
Cupriavidus basilensis FW507-4G11 0.68 RR42_RS12200 isocitrate lyase 0.43 RR42_RS11795 PEP synthetase regulatory protein low > 128
Xanthomonas campestris pv. campestris strain 8004 0.68 Xcc-8004.311.1 Isocitrate lyase (EC 4.1.3.1) 0.40 Xcc-8004.2415.1 FIG137360: hypothetical protein low > 74
Rhodanobacter denitrificans FW104-10B01 0.68 LRK54_RS10585 isocitrate lyase 0.43 LRK54_RS16875 kinase/pyrophosphorylase low > 59
Rhodanobacter denitrificans MT42 0.68 LRK55_RS10225 isocitrate lyase 0.43 LRK55_RS16590 pyruvate, water dikinase regulatory protein low > 63
Burkholderia phytofirmans PsJN 0.68 BPHYT_RS12285 isocitrate lyase 0.43 BPHYT_RS12060 hypothetical protein low > 109
Rhodanobacter sp. FW510-T8 0.67 OKGIIK_13320 aceA isocitrate lyase 0.42 OKGIIK_07965 ppsR phosphoenolpyruvate synthase regulatory protein low > 52
Dyella japonica UNC79MFTsu3.2 0.67 ABZR86_RS13490 isocitrate lyase 0.44 ABZR86_RS07245 pyruvate, water dikinase regulatory protein low > 74
Ralstonia solanacearum IBSBF1503 0.67 RALBFv3_RS00150 isocitrate lyase 0.45 RALBFv3_RS00470 kinase/pyrophosphorylase — —
Ralstonia solanacearum UW163 0.67 UW163_RS13480 isocitrate lyase 0.45 UW163_RS13800 kinase/pyrophosphorylase — —
Ralstonia solanacearum PSI07 0.67 RPSI07_RS17335 isocitrate lyase 0.44 RPSI07_RS17020 kinase/pyrophosphorylase — —
Ralstonia solanacearum GMI1000 0.66 RS_RS06810 isocitrate lyase 0.44 RS_RS07125 phosphoenolpyruvate synthase regulatory protein — —
Ralstonia sp. UNC404CL21Col 0.66 ABZR87_RS11590 isocitrate lyase 0.44 ABZR87_RS11920 pyruvate, water dikinase regulatory protein — —
Azospirillum sp. SherDot2 0.59 MPMX19_05830 Isocitrate lyase 0.18 MPMX19_02558 Putative pyruvate, phosphate dikinase regulatory protein — —
Sinorhizobium meliloti 1021 0.57 SMc00768 isocitrate lyase 0.16 SMc02793 hypothetical protein low > 103
Rhizobium sp. OAE497 0.57 ABIE40_RS03255 isocitrate lyase 0.14 ABIE40_RS19240 pyruvate, water dikinase regulatory protein low > 107
Agrobacterium fabrum C58 0.57 Atu0607 isocitrate lyase 0.17 Atu0001 hypothetical protein low > 89
Brevundimonas sp. GW460-12-10-14-LB2 0.56 A4249_RS02595 isocitrate lyase 0.17 A4249_RS13670 kinase/pyrophosphorylase — —
Azospirillum brasilense Sp245 0.56 AZOBR_RS02405 isocitrate lyase 0.18 AZOBR_RS01755 hypothetical protein low > 97
Caulobacter crescentus NA1000 0.17 CCNA_01841 isocitrate lyase 0.18 CCNA_00001 ATP/GTP-binding protein low > 66
Caulobacter crescentus NA1000 Δfur 0.17 CCNA_01841 isocitrate lyase 0.18 CCNA_00001 ATP/GTP-binding protein low > 67
Acinetobacter radioresistens SK82 0.16 MPMX26_02319 Isocitrate lyase 0.44 MPMX26_01167 Phosphoenolpyruvate synthase regulatory protein — —
Alteromonas macleodii MIT1002 0.16 MIT1002_02831 Isocitrate lyase 0.53 MIT1002_01815 Phosphoenolpyruvate synthase regulatory protein low > 70
Rhodopseudomonas palustris CGA009 0.15 TX73_022775 isocitrate lyase 0.16 TX73_001550 kinase/pyrophosphorylase — —
Sphingomonas koreensis DSMZ 15582 0.15 Ga0059261_1963 Isocitrate lyase 0.21 Ga0059261_2196 Uncharacterized protein conserved in bacteria low > 68

Not shown: 3 genomes with orthologs for b4015 only; 8 genomes with orthologs for b1703 only