Conservation of cofitness between b0356 and b1109 in Escherichia coli BW25113

74 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0356 frmA alcohol dehydrogenase class III/glutathione-dependent formaldehyde dehydrogenase (NCBI) 1.0 b1109 ndh respiratory NADH dehydrogenase 2/cupric reductase (NCBI) 0.21 4
Escherichia coli ECRC101 0.99 OKFHMN_08740 frmA S-(hydroxymethyl)glutathione dehydrogenase 0.99 OKFHMN_03495 ndh NADH-quinone dehydrogenase — —
Escherichia coli ECRC62 0.99 BNILDI_23065 frmA S-(hydroxymethyl)glutathione dehydrogenase 1.00 BNILDI_19185 ndh NADH-quinone dehydrogenase — —
Escherichia coli ECRC99 0.99 KEDOAH_19230 frmA S-(hydroxymethyl)glutathione dehydrogenase 0.99 KEDOAH_24260 ndh NADH-quinone dehydrogenase — —
Escherichia coli ECRC102 0.99 NIAGMN_06795 frmA S-(hydroxymethyl)glutathione dehydrogenase 0.99 NIAGMN_24335 ndh NADH-quinone dehydrogenase — —
Escherichia coli ECOR38 0.99 HEPCGN_07365 frmA S-(hydroxymethyl)glutathione dehydrogenase 1.00 HEPCGN_23990 ndh NADH-quinone dehydrogenase low > 85
Escherichia coli BL21 0.99 ECD_00310 alcohol dehydrogenase class III; glutathione-dependent formaldehyde dehydrogenase 1.00 ECD_01105 respiratory NADH dehydrogenase 2/cupric reductase low > 60
Escherichia coli ECRC98 0.99 JDDGAC_12395 frmA S-(hydroxymethyl)glutathione dehydrogenase 0.99 JDDGAC_07155 ndh NADH-quinone dehydrogenase — —
Escherichia coli ECRC101 0.99 MCAODC_27970 frmA S-(hydroxymethyl)glutathione dehydrogenase 0.99 MCAODC_22855 ndh NADH-quinone dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_03314 S-(hydroxymethyl)glutathione dehydrogenase 1.00 OHPLBJKB_02557 NADH dehydrogenase low > 73
Escherichia coli ECOR27 0.99 NOLOHH_01650 frmA S-(hydroxymethyl)glutathione dehydrogenase 1.00 NOLOHH_21020 ndh NADH-quinone dehydrogenase low > 57
Escherichia fergusonii Becca 0.99 EFB2_03694 S-(hydroxymethyl)glutathione dehydrogenase 1.00 EFB2_02866 NADH dehydrogenase low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS02210 S-(hydroxymethyl)glutathione dehydrogenase 1.00 ECOLIN_RS06400 NADH-quinone dehydrogenase low > 52
Burkholderia phytofirmans PsJN 0.91 BPHYT_RS00510 S-(hydroxymethyl)glutathione dehydrogenase 0.43 BPHYT_RS33605 FAD-dependent pyridine nucleotide-disulfide oxidoreductase low > 109
Lysobacter sp. OAE881 0.90 ABIE51_RS18925 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.17 ABIE51_RS02115 NAD(P)/FAD-dependent oxidoreductase low > 62
Pseudomonas stutzeri RCH2 0.89 Psest_0890 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.54 Psest_0715 NADH dehydrogenase, FAD-containing subunit low > 67
Pseudomonas syringae pv. syringae B728a 0.88 Psyr_2956 Zinc-containing alcohol dehydrogenase superfamily 0.51 Psyr_0790 FAD-dependent pyridine nucleotide-disulfide oxidoreductase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.88 Psyr_2956 Zinc-containing alcohol dehydrogenase superfamily 0.51 Psyr_0790 FAD-dependent pyridine nucleotide-disulfide oxidoreductase low > 86
Acidovorax sp. GW101-3H11 0.87 Ac3H11_3163 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) 0.16 Ac3H11_2167 NADH dehydrogenase (EC 1.6.99.3) low > 79
Acinetobacter radioresistens SK82 0.86 MPMX26_00881 S-(hydroxymethyl)glutathione dehydrogenase 0.38 MPMX26_01006 NADH dehydrogenase — —
Klebsiella michiganensis M5al 0.84 BWI76_RS13260 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.91 BWI76_RS11175 NADH dehydrogenase — —
Xanthomonas campestris pv. campestris strain 8004 0.83 Xcc-8004.982.1 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) 0.18 Xcc-8004.4769.1 NADH dehydrogenase (EC 1.6.99.3) low > 74
Enterobacter sp. TBS_079 0.83 MPMX20_02209 S-(hydroxymethyl)glutathione dehydrogenase 0.91 MPMX20_01790 NADH dehydrogenase low > 85
Enterobacter asburiae PDN3 0.83 EX28DRAFT_1257 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.92 EX28DRAFT_1821 NADH dehydrogenase, FAD-containing subunit low > 76
Dyella japonica UNC79MFTsu3.2 0.81 ABZR86_RS17285 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.14 ABZR86_RS12540 NAD(P)/FAD-dependent oxidoreductase low > 74
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.80 GFF2617 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) 0.96 GFF3392 NADH dehydrogenase (EC 1.6.99.3) low > 78
Shewanella amazonensis SB2B 0.75 Sama_0004 alcohol dehydrogenase, zinc-binding (RefSeq) 0.42 Sama_0936 NADH dehydrogenase (RefSeq) low > 62
Pseudomonas fluorescens GW456-L13 0.75 PfGW456L13_3630 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) 0.52 PfGW456L13_1496 NADH dehydrogenase (EC 1.6.99.3) low > 87
Alteromonas macleodii MIT1002 0.75 MIT1002_03089 S-(hydroxymethyl)glutathione dehydrogenase 0.52 MIT1002_03885 NADH dehydrogenase low > 70
Marinobacter adhaerens HP15 0.75 HP15_4017 formaldehyde dehydrogenase (glutathione-dependent) 0.51 HP15_3830 FAD-dependent pyridine nucleotide-disulfide oxidoreductase low > 73
Pseudomonas simiae WCS417 0.75 PS417_06330 S-(hydroxymethyl)glutathione dehydrogenase 0.52 PS417_03855 NADH dehydrogenase low > 88
Shewanella loihica PV-4 0.75 Shew_1540 alcohol dehydrogenase (RefSeq) 0.55 Shew_2195 NADH dehydrogenase (RefSeq) low > 60
Pseudomonas fluorescens SBW25-INTG 0.75 PFLU_RS06395 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.52 PFLU_RS03905 NAD(P)/FAD-dependent oxidoreductase low > 109
Pseudomonas sp. S08-1 0.75 OH686_18150 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.52 OH686_16450 NADH dehydrogenase low > 80
Pseudomonas fluorescens FW300-N2E3 0.75 AO353_16580 S-(hydroxymethyl)glutathione dehydrogenase 0.52 AO353_14255 NADH dehydrogenase low > 101
Pseudomonas fluorescens SBW25 0.75 PFLU_RS06395 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.52 PFLU_RS03905 NAD(P)/FAD-dependent oxidoreductase low > 109
Pantoea sp. MT58 0.74 IAI47_06705 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.84 IAI47_11985 NAD(P)/FAD-dependent oxidoreductase low > 76
Serratia liquefaciens MT49 0.74 IAI46_07885 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.82 IAI46_09910 NAD(P)/FAD-dependent oxidoreductase low > 86
Pseudomonas putida KT2440 0.74 PP_1616 formaldehyde dehydrogenase, glutathione-dependent 0.55 PP_0626 NADH dehydrogenase low > 96
Pectobacterium carotovorum WPP14 0.74 HER17_RS12790 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.80 HER17_RS08735 NAD(P)/FAD-dependent oxidoreductase low > 75
Shewanella sp. ANA-3 0.74 Shewana3_1837 alcohol dehydrogenase (RefSeq) 0.40 Shewana3_3123 FAD-dependent pyridine nucleotide-disulphide oxidoreductase (RefSeq) low > 73
Dickeya dadantii 3937 0.74 DDA3937_RS09325 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.80 DDA3937_RS13040 NAD(P)/FAD-dependent oxidoreductase 0.57 64
Pseudomonas fluorescens FW300-N2C3 0.74 AO356_05920 S-(hydroxymethyl)glutathione dehydrogenase 0.53 AO356_15965 NADH dehydrogenase low > 104
Pseudomonas fluorescens FW300-N2E2 0.73 Pf6N2E2_3044 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) 0.52 Pf6N2E2_5132 NADH dehydrogenase (EC 1.6.99.3) low > 103
Shewanella oneidensis MR-1 0.73 SO2054 adhC alcohol dehydrogenase class III (NCBI ptt file) 0.40 SO3517 ndh NADH dehydrogenase (NCBI ptt file) low > 76
Dickeya dianthicola 67-19 0.73 HGI48_RS09350 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.80 HGI48_RS13105 NAD(P)/FAD-dependent oxidoreductase low > 71
Dickeya dianthicola ME23 0.73 DZA65_RS09655 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.79 DZA65_RS13575 NAD(P)/FAD-dependent oxidoreductase low > 75
Rahnella sp. WP5 0.73 EX31_RS18715 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.82 EX31_RS24510 NAD(P)/FAD-dependent oxidoreductase low > 89
Synechococcus elongatus PCC 7942 0.73 Synpcc7942_0459 glutathione-dependent formaldehyde dehydrogenase 0.17 Synpcc7942_0101 ndbA type 2 NADH dehydrogenase — —
Pseudomonas fluorescens FW300-N1B4 0.73 Pf1N1B4_3108 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) 0.52 Pf1N1B4_2826 NADH dehydrogenase (EC 1.6.99.3) low > 87
Pseudomonas sp. RS175 0.73 PFR28_00420 S-(hydroxymethyl)glutathione dehydrogenase 0.52 PFR28_03740 NADH dehydrogenase low > 88
Erwinia tracheiphila SCR3 0.73 LU632_RS17270 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.82 LU632_RS14740 NAD(P)/FAD-dependent oxidoreductase low > 74
Azospirillum brasilense Sp245 0.72 AZOBR_RS16515 S-(hydroxymethyl)glutathione dehydrogenase 0.16 AZOBR_RS00545 FAD-dependent pyridine nucleotide-disulfide oxidoreductase low > 97
Rhodanobacter denitrificans FW104-10B01 0.71 LRK54_RS09935 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.36 LRK54_RS07490 NAD(P)/FAD-dependent oxidoreductase low > 59
Rhodanobacter denitrificans MT42 0.71 LRK55_RS09575 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.36 LRK55_RS07230 NAD(P)/FAD-dependent oxidoreductase low > 63
Rhodopseudomonas palustris CGA009 0.64 TX73_010080 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.45 TX73_005675 NAD(P)/FAD-dependent oxidoreductase low > 86
Sphingomonas koreensis DSMZ 15582 0.63 Ga0059261_1819 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.49 Ga0059261_1466 NADH dehydrogenase, FAD-containing subunit low > 68
Ralstonia sp. UNC404CL21Col 0.62 ABZR87_RS08285 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.44 ABZR87_RS15675 NAD(P)/FAD-dependent oxidoreductase low > 80
Ralstonia solanacearum UW163 0.62 UW163_RS01260 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.43 UW163_RS09925 NAD(P)/FAD-dependent oxidoreductase — —
Ralstonia solanacearum IBSBF1503 0.62 RALBFv3_RS12345 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.43 RALBFv3_RS03745 NAD(P)/FAD-dependent oxidoreductase low > 76
Bosea sp. OAE506 0.62 ABIE41_RS09635 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.11 ABIE41_RS00975 NAD(P)/FAD-dependent oxidoreductase low > 77
Ralstonia solanacearum GMI1000 0.61 RS_RS17530 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.43 RS_RS11190 NAD(P)/FAD-dependent oxidoreductase low > 80
Ralstonia solanacearum PSI07 0.61 RPSI07_RS20965 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.43 RPSI07_RS13485 NAD(P)/FAD-dependent oxidoreductase low > 81
Cupriavidus basilensis FW507-4G11 0.61 RR42_RS25775 alcohol dehydrogenase 0.49 RR42_RS26100 pyridine nucleotide-disulfide oxidoreductase — —
Paraburkholderia graminis OAS925 0.61 ABIE53_003402 S-(hydroxymethyl)glutathione dehydrogenase/alcohol dehydrogenase 0.42 ABIE53_004853 NADH dehydrogenase low > 113
Variovorax sp. OAS795 0.61 ABID97_RS10235 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.48 ABID97_RS26565 NAD(P)/FAD-dependent oxidoreductase — —
Paraburkholderia sabiae LMG 24235 0.61 QEN71_RS02555 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.43 QEN71_RS17890 NAD(P)/FAD-dependent oxidoreductase low > 153
Paraburkholderia bryophila 376MFSha3.1 0.61 H281DRAFT_04166 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase 0.43 H281DRAFT_06021 NADH dehydrogenase low > 103
Sinorhizobium meliloti 1021 0.61 SM_b20170 glutathione-dependent formaldehyde dehydrogenase 0.16 SMc04452 NADH dehydrogenase transmembrane protein — —
Variovorax sp. SCN45 0.61 GFF2941 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) 0.16 GFF6814 NADH dehydrogenase (EC 1.6.99.3) low > 127
Rhizobium sp. OAE497 0.60 ABIE40_RS09860 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.14 ABIE40_RS30795 NAD(P)/FAD-dependent oxidoreductase low > 107
Hydrogenophaga sp. GW460-11-11-14-LB1 0.60 GFF3318 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) 0.37 GFF4021 NADH dehydrogenase (EC 1.6.99.3) low > 90
Agrobacterium fabrum C58 0.60 Atu1670 alcohol dehydrogenase class III 0.15 Atu2023 NADH dehydrogenase low > 89
Herbaspirillum seropedicae SmR1 0.59 HSERO_RS13615 alcohol dehydrogenase 0.17 HSERO_RS08760 FAD-dependent pyridine nucleotide-disulfide oxidoreductase low > 78
Mycobacterium tuberculosis H37Rv 0.28 Rv0761c Possible zinc-containing alcohol dehydrogenase NAD dependent AdhB 0.16 Rv1854c Probable NADH dehydrogenase Ndh — —

Not shown: 10 genomes with orthologs for b0356 only; 8 genomes with orthologs for b1109 only