Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| Rhodopseudomonas palustris CGA009 | TX73_003375 | | cyclohexanecarboxylate-CoA ligase | insig. | 100 | 100 |
o | Castellaniella sp019104865 MT123 | ABCV34_RS03750 | | cyclohexanecarboxylate-CoA ligase | insig. | 73 | 100 |
o | Cupriavidus basilensis FW507-4G11 | RR42_RS23705 | | cyclohexanecarboxylate--CoA ligase | insig. | 70 | 100 |
o | Acinetobacter radioresistens SK82 | MPMX26_01930 | | Medium-chain fatty-acid--CoA ligase | no data | 60 | 99 |
o | Marinobacter adhaerens HP15 | HP15_4144 | | short chain acyl-CoA synthetase | cofit | 53 | 99 |
o | Variovorax sp. SCN45 | GFF4304 | | Cyclohexanecarboxylate--CoA ligase | insig. | 53 | 96 |
o | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3540 | | Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 37 | 99 |
o | Escherichia coli BL21 | ECD_01670 | | short chain acyl-CoA synthetase, anaerobic | no data | 38 | 97 |
o | Escherichia coli ECRC101 | OKFHMN_27150 | fadK | medium-chain fatty-acid--CoA ligase | insig. | 38 | 97 |
o | Escherichia coli ECRC102 | NIAGMN_00915 | fadK | medium-chain fatty-acid--CoA ligase | insig. | 38 | 97 |
o | Escherichia coli ECRC98 | JDDGAC_01725 | fadK | medium-chain fatty-acid--CoA ligase | no data | 38 | 97 |
o | Escherichia coli ECRC99 | KEDOAH_00960 | fadK | medium-chain fatty-acid--CoA ligase | no data | 38 | 97 |
o | Escherichia coli ECOR27 | NOLOHH_17670 | fadK | medium-chain fatty-acid--CoA ligase | no data | 38 | 97 |
o | Escherichia fergusonii Becca | EFB2_02290 | | Medium-chain fatty-acid--CoA ligase | insig. | 38 | 97 |
o | Escherichia coli BW25113 | b1701 | fadK | short chain acyl-CoA synthetase, anaerobic (RefSeq) | insig. | 38 | 97 |
o | Escherichia coli Nissle 1917 | ECOLIN_RS09505 | | medium-chain fatty-acid--CoA ligase | no data | 38 | 97 |
o | Escherichia coli ECOR38 | HEPCGN_05535 | fadK | medium-chain fatty-acid--CoA ligase | cofit | 38 | 97 |
o | Escherichia coli ECRC62 | BNILDI_16460 | fadK | medium-chain fatty-acid--CoA ligase | insig. | 38 | 92 |
o | Escherichia coli ECRC101 | MCAODC_18260 | fadK | medium-chain fatty-acid--CoA ligase | insig. | 38 | 90 |
o | Burkholderia phytofirmans PsJN | BPHYT_RS31895 | | hypothetical protein | insig. | 34 | 98 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS36410 | | acyl-CoA synthetase | insig. | 34 | 89 |
| Pseudomonas fluorescens GW456-L13 | PfGW456L13_2521 | | Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD3 | insig. | 33 | 89 |
| Acinetobacter radioresistens SK82 | MPMX26_00634 | | 3-[(3aS,4S,7aS)-7a-methyl-1, 5-dioxo-octahydro-1H-inden-4-yl]propanoyl:CoA ligase | insig. | 30 | 95 |
| Methanococcus maripaludis JJ | MMJJ_RS02080 | | AMP-binding protein | insig. | 31 | 89 |
| Methanococcus maripaludis S2 | MMP_RS02990 | | AMP-binding protein | insig. | 30 | 89 |
| Shewanella amazonensis SB2B | Sama_1904 | | AMP-binding domain protein (RefSeq) | insig. | 31 | 89 |
| Pseudomonas putida KT2440 | PP_3458 | | Butyrate--CoA ligase | sig. | 32 | 95 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4967 | | Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 31 | 95 |
o | Pseudomonas simiae WCS417 | PS417_13215 | | Triostin synthetase I | insig. | 32 | 96 |
| Pseudomonas stutzeri RCH2 | Psest_1086 | | Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II | insig. | 32 | 95 |
| Pseudomonas putida KT2440 | PP_4063 | | putative Long-chain-fatty-acid-CoA ligase | strong | 31 | 95 |
| Mycobacterium tuberculosis H37Rv | Rv2505c | | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | insig. | 32 | 95 |
| Pseudomonas simiae WCS417 | PS417_17010 | | AMP-binding protein | insig. | 32 | 95 |
| Caulobacter crescentus NA1000 | CCNA_01017 | | acyl-CoA synthetase | sig. | 32 | 92 |
| Caulobacter crescentus NA1000 Δfur | CCNA_01017 | | acyl-CoA synthetase | cofit | 32 | 92 |
| Shewanella loihica PV-4 | Shew_2593 | | acyl-CoA synthetase (RefSeq) | insig. | 30 | 95 |
| Variovorax sp. SCN45 | GFF2007 | | Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16) | insig. | 32 | 95 |
| Azospirillum sp. SherDot2 | MPMX19_03344 | | 3-[(3aS,4S,7aS)-7a-methyl-1, 5-dioxo-octahydro-1H-inden-4-yl]propanoyl:CoA ligase | insig. | 30 | 95 |
| Marinobacter adhaerens HP15 | HP15_999 | | acyl-CoA synthase | insig. | 31 | 95 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_0771 | | Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II | insig. | 33 | 89 |
| Pseudomonas fluorescens SBW25 | PFLU_RS18960 | | AMP-binding protein | cofit | 31 | 95 |
| Pseudomonas fluorescens SBW25-INTG | PFLU_RS18960 | | AMP-binding protein | insig. | 31 | 95 |
| Shewanella oneidensis MR-1 | SO1971 | | AMP-binding family protein (NCBI ptt file) | insig. | 29 | 95 |
| Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2190 | | Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 31 | 95 |
| Pseudomonas fluorescens FW300-N2E3 | AO353_20355 | | AMP-binding protein | insig. | 30 | 95 |
| Variovorax sp. OAS795 | ABID97_RS25135 | | AMP-binding protein | insig. | 32 | 95 |
| Pseudomonas fluorescens GW456-L13 | PfGW456L13_2593 | | Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 30 | 95 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS29035 | | acyl-CoA synthetase | insig. | 33 | 88 |
| Variovorax sp. OAS795 | ABID97_RS11345 | | class I adenylate-forming enzyme family protein | insig. | 33 | 89 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS26915 | | AMP-binding protein | strong | 32 | 94 |
| Pseudomonas sp. RS175 | PFR28_01261 | | 3-[(3aS,4S,7aS)-7a-methyl-1, 5-dioxo-octahydro-1H-inden-4-yl]propanoyl:CoA ligase | insig. | 32 | 95 |
| Ralstonia solanacearum IBSBF1503 | RALBFv3_RS11360 | | AMP-binding protein | sig. | 31 | 95 |
| Ralstonia solanacearum UW163 | UW163_RS02225 | | AMP-binding protein | insig. | 31 | 95 |
| Pseudomonas putida KT2440 | PP_3553 | | AMP-binding domain protein | strong | 34 | 90 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS29430 | | acyl-CoA synthetase | insig. | 33 | 82 |
| Dechlorosoma suillum PS | Dsui_2069 | | acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II | insig. | 33 | 94 |
| Alteromonas macleodii MIT1002 | MIT1002_03360 | | Long-chain-fatty-acid--CoA ligase | insig. | 29 | 89 |
| Ralstonia solanacearum GMI1000 | RS_RS02190 | | AMP-binding protein | insig. | 31 | 93 |
| Paraburkholderia sabiae LMG 24235 | QEN71_RS29275 | | AMP-binding protein | insig. | 31 | 89 |
| Shewanella sp. ANA-3 | Shewana3_2475 | | AMP-binding domain protein (RefSeq) | insig. | 29 | 95 |
| Desulfovibrio vulgaris Hildenborough JW710 | DVU3065 | | AMP-binding enzyme family protein (TIGR) | insig. | 30 | 95 |
| Dinoroseobacter shibae DFL-12 | Dshi_3403 | | AMP-dependent synthetase and ligase (RefSeq) | cofit | 30 | 89 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_0835 | | Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II | insig. | 32 | 89 |
| Ralstonia solanacearum PSI07 | RPSI07_RS21845 | | AMP-binding protein | insig. | 31 | 94 |
| Desulfovibrio vulgaris Miyazaki F | DvMF_2357 | | AMP-binding domain protein (RefSeq) | sig. | 30 | 95 |
o | Serratia liquefaciens MT49 | IAI46_18320 | | (2,3-dihydroxybenzoyl)adenylate synthase | insig. | 29 | 97 |
o | Vibrio cholerae E7946 ATCC 55056 | CSW01_04005 | | 2,3-dihydroxybenzoate-AMP ligase | insig. | 29 | 95 |
| Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1726 | | 3-methylmercaptopropionyl-CoA ligase (DmdB) | sig. | 32 | 90 |
| Pseudomonas fluorescens FW300-N2C3 | AO356_01575 | | AMP-binding protein | insig. | 30 | 95 |
| Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_3988 | | Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 29 | 95 |
o | Klebsiella michiganensis M5al | BWI76_RS07750 | | 2,3-dihydroxybenzoate-AMP ligase | insig. | 30 | 90 |
| Acidovorax sp. GW101-3H11 | Ac3H11_3009 | | Acetoacetate--CoA ligase (EC 6.2.1.16) (from data) | strong | 31 | 95 |
| Rhodanobacter denitrificans MT42 | LRK55_RS08165 | | AMP-binding protein | insig. | 31 | 95 |
| Rhodanobacter denitrificans FW104-10B01 | LRK54_RS08400 | | AMP-binding protein | insig. | 31 | 95 |
o | Dickeya dianthicola 67-19 | HGI48_RS14650 | | (2,3-dihydroxybenzoyl)adenylate synthase | insig. | 32 | 90 |
| Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02398 | | fatty-acyl-CoA synthase | sig. | 30 | 89 |
| Pseudomonas stutzeri RCH2 | Psest_2477 | | Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II | insig. | 30 | 95 |
| Ralstonia sp. UNC404CL21Col | ABZR87_RS07325 | | AMP-binding protein | insig. | 30 | 99 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4501 | | 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) [enterobactin] siderophore | insig. | 30 | 96 |
| Paraburkholderia graminis OAS925 | ABIE53_000249 | | fatty-acyl-CoA synthase | sig. | 29 | 95 |
| Bacteroides ovatus ATCC 8483 | BACOVA_01082 | | AMP-binding domain protein | insig. | 29 | 95 |
| Burkholderia phytofirmans PsJN | BPHYT_RS19375 | | AMP-binding protein | insig. | 29 | 89 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF907 | | 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) | insig. | 30 | 96 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS31975 | | fatty acid--CoA ligase | insig. | 30 | 99 |
| Ralstonia solanacearum IBSBF1503 | RALBFv3_RS09735 | | AMP-dependent synthetase | sig. | 30 | 93 |
| Ralstonia solanacearum UW163 | UW163_RS03845 | | AMP-dependent synthetase | insig. | 30 | 93 |
| Marinobacter adhaerens HP15 | HP15_1039 | | acyl-CoA synthetase | sig. | 32 | 91 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS29385 | | long-chain fatty acid--CoA ligase | insig. | 32 | 95 |
| Bacteroides stercoris CC31F | HMPREF1181_RS01205 | | AMP-binding protein | insig. | 28 | 95 |
| Mycobacterium tuberculosis H37Rv | Rv2384 | | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | insig. | 33 | 97 |
| Dinoroseobacter shibae DFL-12 | Dshi_2999 | | AMP-dependent synthetase and ligase (RefSeq) | strong | 32 | 88 |
| Ralstonia sp. UNC404CL21Col | ABZR87_RS05005 | | AMP-binding protein | insig. | 30 | 89 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS27915 | | acyl-CoA synthetase | sig. | 34 | 90 |
| Caulobacter crescentus NA1000 | CCNA_02483 | | 4-coumarate--CoA ligase | cofit | 32 | 92 |
| Caulobacter crescentus NA1000 Δfur | CCNA_02483 | | 4-coumarate--CoA ligase | cofit | 32 | 92 |
| Escherichia fergusonii Becca | EFB2_03498 | | Enterobactin synthase component E | insig. | 29 | 96 |
| Escherichia coli Nissle 1917 | ECOLIN_RS03260 | | (2,3-dihydroxybenzoyl)adenylate synthase EntE | insig. | 29 | 96 |
o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03112 | | Enterobactin synthase component E | insig. | 29 | 96 |
| Escherichia coli BW25113 | b0594 | entE | 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex (NCBI) | insig. | 29 | 96 |
| Azospirillum brasilense Sp245 | AZOBR_RS06255 | | acyl-CoA synthetase | sig. | 32 | 90 |