Homologs of Rv0511 from Mycobacterium tuberculosis H37Rv

Probable uroporphyrin-III C-methyltransferase HemD (uroporphyrinogen III methylase) (urogen III methylase) (SUMT) (urogen III methylase) (UROM)
SEED: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
KEGG: uroporphyrinogen III methyltransferase / synthase

Top 100 hits from BLASTp (E < 0.01)

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Orth Species Gene Name Description Fitness %Id Cov
  Mycobacterium tuberculosis H37Rv Rv0511 Probable uroporphyrin-III C-methyltransferase HemD (uroporphyrinogen III methylase) (urogen III methylase) (SUMT) (urogen III methylase) (UROM) no data 100 100
o Desulfovibrio vulgaris Hildenborough JW710 DVU0734 cysG-1 uroporphyrinogen III synthase/methyltransferase (TIGR) no data 29 94
  Desulfovibrio vulgaris Miyazaki F DvMF_2767 uroporphyrin-III C-methyltransferase (RefSeq) no data 29 94
  Fusobacterium nucleatum SB010 HUW76_06215 uroporphyrinogen-III C-methyltransferase cofit 26 95
  Serratia liquefaciens MT49 IAI46_23670 uroporphyrinogen-III C-methyltransferase insig. 28 51
  Enterobacter sp. TBS_079 MPMX20_03639 Siroheme synthase insig. 30 50
  Enterobacter asburiae PDN3 EX28DRAFT_2849 uroporphyrin-III C-methyltransferase strong 29 50
  Escherichia coli BL21 ECD_03219 fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase insig. 26 50
  Escherichia coli HS(pFamp)R (ATCC 700891) OHPLBJKB_00334 Siroheme synthase insig. 26 50
  Escherichia coli BW25113 b3368 cysG fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) strong 26 50
  Escherichia coli ECOR27 NOLOHH_08980 cysG siroheme synthase CysG cofit 26 50
  Escherichia coli ECOR38 HEPCGN_16010 cysG siroheme synthase CysG cofit 26 50
  Escherichia coli ECRC101 OKFHMN_17180 cysG siroheme synthase CysG insig. 26 50
  Escherichia coli ECRC101 MCAODC_07710 cysG siroheme synthase CysG insig. 26 50
  Escherichia coli ECRC102 NIAGMN_14950 cysG siroheme synthase CysG insig. 26 50
  Escherichia coli ECRC62 BNILDI_02540 cysG siroheme synthase CysG insig. 26 50
  Escherichia coli ECRC98 JDDGAC_20810 cysG siroheme synthase CysG no data 26 50
  Escherichia coli ECRC99 KEDOAH_10960 cysG siroheme synthase CysG no data 26 50
  Shewanella amazonensis SB2B Sama_2892 uroporphyrin-III C-methyltransferase (RefSeq) strong 27 51
  Magnetospirillum magneticum AMB-1 AMB_RS17015 uroporphyrinogen-III C-methyltransferase no data 30 50
  Escherichia fergusonii Becca EFB2_00454 Siroheme synthase insig. 25 50
  Escherichia coli Nissle 1917 ECOLIN_RS19285 siroheme synthase CysG insig. 25 50
  Pectobacterium carotovorum WPP14 HER17_RS01835 siroheme synthase CysG insig. 26 50
  Enterobacter sp. TBS_079 MPMX20_04271 Siroheme synthase sig. 25 50
  Pseudomonas syringae pv. syringae B728a Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase strong 29 50
  Pseudomonas syringae pv. syringae B728a ΔmexB Psyr_3174 uroporphyrinogen-III C-methyltransferase / precorrin-2 dehydrogenase cofit 29 50
  Rahnella sp. WP5 EX31_RS04680 uroporphyrinogen-III C-methyltransferase insig. 26 51
  Enterobacter asburiae PDN3 EX28DRAFT_4160 uroporphyrin-III C-methyltransferase insig. 25 50
  Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 GFF3700 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) insig. 25 50
  Shewanella loihica PV-4 Shew_0672 uroporphyrin-III C-methyltransferase (RefSeq) cofit 26 49
  Pectobacterium carotovorum WPP14 HER17_RS04280 siroheme synthase CysG cofit 27 49
  Pseudomonas fluorescens FW300-N2C3 AO356_25030 uroporphyrin-III methyltransferase insig. 30 43
  Pseudomonas fluorescens FW300-N2E2 Pf6N2E2_696 Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) insig. 30 43
  Pseudomonas sp. S08-1 OH686_00285 Precorrin-2 oxidase or Sirohydrochlorin ferrochelatase activity of CysG / Uroporphyrinogen-III methyltransferase strong 27 51
  Klebsiella michiganensis M5al BWI76_RS26055 siroheme synthase strong 25 50
  Pseudomonas putida KT2440 PP_3999 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase strong 26 50
  Rhodospirillum rubrum S1H Rru_A3362 Uroporphyrin-III C-methyltransferase-like (NCBI) sig. 31 50
  Pseudomonas sp. RS175 PFR28_02603 Siroheme synthase strong 28 50
  Pseudomonas fluorescens FW300-N2C3 AO356_22200 sirohydrochlorin ferrochelatase strong 28 50
  Pseudomonas fluorescens FW300-N2E2 Pf6N2E2_302 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) strong 28 50
  Pseudomonas simiae WCS417 PS417_16465 sirohydrochlorin ferrochelatase strong 28 50
  Marinobacter adhaerens HP15 HP15_1815 siroheme synthase strong 26 49
  Pseudomonas fluorescens SBW25 PFLU_RS18505 uroporphyrinogen-III C-methyltransferase strong 28 50
  Pseudomonas fluorescens SBW25-INTG PFLU_RS18505 uroporphyrinogen-III C-methyltransferase strong 28 50
  Alteromonas macleodii MIT1002 MIT1002_00665 Siroheme synthase no data 26 50
  Pseudomonas stutzeri RCH2 Psest_2037 uroporphyrin-III C-methyltransferase strong 26 51
  Shewanella sp. ANA-3 Shewana3_0862 uroporphyrinogen-III C-methyltransferase (RefSeq) strong 25 50
  Rhizobium sp. OAE497 ABIE40_RS11110 uroporphyrinogen-III C-methyltransferase insig. 27 49
  Pseudomonas fluorescens FW300-N1B4 Pf1N1B4_4065 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) strong 28 50
  Lysobacter sp. OAE881 ABIE51_RS15855 siroheme synthase CysG strong 28 49
  Pseudomonas fluorescens FW300-N2E3 AO353_27625 sirohydrochlorin ferrochelatase no data 28 51
  Synechococcus elongatus PCC 7942 Synpcc7942_0272 hemD Uroporphyrinogen-III synthase no data 29 45
  Pantoea sp. MT58 IAI47_04175 uroporphyrinogen-III C-methyltransferase strong 28 51
  Pseudomonas stutzeri RCH2 Psest_0810 uroporphyrin-III C-methyltransferase strong 28 42
  Rahnella sp. WP5 EX31_RS07885 uroporphyrinogen-III C-methyltransferase cofit 28 49
  Azospirillum sp. SherDot2 MPMX19_05563 Uroporphyrinogen-III C-methyltransferase no data 30 49
  Shewanella oneidensis MR-1 SO3728 cobA uroporphyrin-III C-methyltransferase (NCBI ptt file) strong 25 50
  Mycobacterium tuberculosis H37Rv Rv2847c Possible multifunctional enzyme siroheme synthase CysG: uroporphyrin-III C-methyltransferase (urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM) + precorrin-2 oxidase + ferrochelatase no data 30 41
  Erwinia tracheiphila SCR3 LU632_RS06420 cysG siroheme synthase CysG strong 27 50
  Kangiella aquimarina DSM 16071 B158DRAFT_2163 uroporphyrin-III C-methyltransferase insig. 26 51
  Pseudomonas fluorescens GW456-L13 PfGW456L13_2656 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) strong 28 50
  Klebsiella michiganensis M5al BWI76_RS22705 siroheme synthase sig. 28 50
  Castellaniella sp019104865 MT123 ABCV34_RS00210 siroheme synthase CysG strong 27 43
  Dechlorosoma suillum PS Dsui_3319 uroporphyrin-III C-methyltransferase strong 27 50
  Acinetobacter radioresistens SK82 MPMX26_00706 Siroheme synthase no data 26 49
  Sinorhizobium meliloti 1021 SMc04284 uroporphyrin-III C-methyltransferase no data 25 49
  Synechococcus elongatus PCC 7942 Synpcc7942_0271 cobA uroporphyrinogen-III C-methyltransferase no data 26 50
  Dinoroseobacter shibae DFL-12 Dshi_3179 uroporphyrin-III C-methyltransferase (RefSeq) insig. 30 42
  Dyella japonica UNC79MFTsu3.2 ABZR86_RS05880 siroheme synthase CysG strong 28 49
  Pseudomonas sp. RS175 PFR28_02239 Siroheme synthase insig. 27 53
  Vibrio cholerae E7946 ATCC 55056 CSW01_12965 uroporphyrinogen-III C-methyltransferase insig. 26 50
  Rahnella sp. WP5 EX31_RS09100 uroporphyrinogen-III C-methyltransferase insig. 29 43
  Phaeobacter inhibens DSM 17395 PGA1_c20740 uroporphyrinogen-III C-methyltransferase CobA strong 30 45
  Pseudomonas fluorescens FW300-N1B4 Pf1N1B4_5773 Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) no data 28 42
  Pseudomonas fluorescens FW300-N2E3 AO353_21925 uroporphyrin-III methyltransferase insig. 27 42
  Dickeya dianthicola 67-19 HGI48_RS14080 uroporphyrinogen-III C-methyltransferase insig. 27 45
  Serratia liquefaciens MT49 IAI46_03710 uroporphyrinogen-III C-methyltransferase cofit 27 51
  Dickeya dadantii 3937 DDA3937_RS14080 uroporphyrinogen-III C-methyltransferase sig. 27 45
  Pectobacterium carotovorum WPP14 HER17_RS07340 uroporphyrinogen-III C-methyltransferase insig. 26 45
  Dickeya dianthicola ME23 DZA65_RS14740 uroporphyrinogen-III C-methyltransferase insig. 27 44
  Magnetospirillum magneticum AMB-1 AMB_RS02650 uroporphyrinogen-III C-methyltransferase cofit 27 50
  Paraburkholderia bryophila 376MFSha3.1 H281DRAFT_00199 uroporphyrinogen III methyltransferase / synthase insig. 29 41
  Dinoroseobacter shibae DFL-12 Dshi_1155 uroporphyrin-III C-methyltransferase (RefSeq) no data 29 44
  Agrobacterium fabrum C58 Atu3899 siroheme synthase insig. 25 46
  Hydrogenophaga sp. GW460-11-11-14-LB1 GFF3661 Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) insig. 28 44
  Rhodanobacter sp. FW510-T8 OKGIIK_05980 cysG siroheme synthase CysG insig. 30 45
  Dickeya dianthicola 67-19 HGI48_RS17000 uroporphyrinogen-III C-methyltransferase cofit 28 50
  Synechococcus elongatus PCC 7942 Synpcc7942_2610 cobA uroporphyrin-III C-methyltransferase no data 26 42
  Dickeya dianthicola ME23 DZA65_RS18075 uroporphyrinogen-III C-methyltransferase strong 28 50
  Agrobacterium fabrum C58 Atu1454 siroheme synthase strong 26 50
  Agrobacterium fabrum C58 Atu2794 uroporphyrin-III C-methyltransferase insig. 25 49
  Pseudomonas putida KT2440 PP_2090 Uroporphyrinogen-III C-methyltransferase sig. 26 44
  Dinoroseobacter shibae DFL-12 Dshi_1692 uroporphyrin-III C-methyltransferase (RefSeq) no data 26 49
  Azospirillum brasilense Sp245 AZOBR_RS18580 uroporphyrin-III methyltransferase no data 25 44
  Dickeya dadantii 3937 DDA3937_RS16930 uroporphyrinogen-III C-methyltransferase strong 27 50
  Methanococcus maripaludis S2 MMP_RS05005 uroporphyrinogen-III C-methyltransferase no data 22 43
  Variovorax sp. OAS795 ABID97_RS16030 uroporphyrinogen-III C-methyltransferase insig. 27 48
  Xanthomonas campestris pv. campestris strain 8004 Xcc-8004.1248.1 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) strong 24 51
  Rhodopseudomonas palustris CGA009 TX73_021850 siroheme synthase CysG cofit 27 50
  Methanococcus maripaludis JJ MMJJ_RS00130 uroporphyrinogen-III C-methyltransferase no data 22 43