| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Variovorax sp. SCN45 | GFF7104 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) | insig. | 100 | 100 |
| | Variovorax sp. OAS795 | ABID97_RS03760 | | fumarylacetoacetate hydrolase family protein | sig. | 62 | 100 |
| | Variovorax sp. SCN45 | GFF5091 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) | insig. | 60 | 97 |
| o | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1829 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 51 | 97 |
| o | Acidovorax sp. GW101-3H11 | Ac3H11_1488 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 42 | 94 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS13535 | | fumarylacetoacetate hydrolase family protein | insig. | 38 | 93 |
| o | Azospirillum sp. SherDot2 | MPMX19_06800 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | insig. | 40 | 98 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS28085 | | fumarylacetoacetate hydrolase family protein | insig. | 37 | 99 |
| | Pseudomonas sp. SVBP6 | COO64_RS13795 | | fumarylacetoacetate hydrolase family protein | insig. | 36 | 94 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_21225 | | 4-hydroxyphenylacetate isomerase | sig. | 36 | 99 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS47555 | | fumarylacetoacetate hydrolase family protein | insig. | 36 | 99 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS27825 | | 4-hydroxyphenylacetate isomerase | insig. | 37 | 88 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03258 | | 5-carboxy-2-oxohept-3-enedioate decarboxylase HpaG1 subunit (EC 4.1.1.68) | insig. | 40 | 88 |
| o | Paraburkholderia graminis OAS925 | ABIE53_005229 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 40 | 94 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS34375 | | fumarylacetoacetate hydrolase family protein | insig. | 38 | 95 |
| o | Klebsiella pneumoniae MKP103 | KDGMDA_12125 | | 2-hydroxyhepta-2 4-diene-1 7-dioate isomerase | insig. | 38 | 94 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS12025 | | fumarylacetoacetate hydrolase family protein | insig. | 38 | 95 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3278 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 38 | 94 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_25595 | | 4-hydroxyphenylacetate isomerase | insig. | 35 | 99 |
| | Enterobacter sp. TBS_079 | MPMX20_00642 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | insig. | 39 | 94 |
| o | Klebsiella michiganensis M5al | BWI76_RS03875 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | sig. | 37 | 94 |
| | Escherichia coli ECRC62 | BNILDI_07885 | hpaG | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | insig. | 38 | 94 |
| | Escherichia coli ECOR27 | NOLOHH_03715 | hpaG | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | insig. | 38 | 94 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03710 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | cofit | 38 | 94 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1307 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 35 | 99 |
| | Escherichia coli BL21 | ECD_04230 | | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | insig. | 37 | 94 |
| | Pseudomonas orientalis W4I3 | QF045_RS12935 | | fumarylacetoacetate hydrolase family protein | insig. | 35 | 99 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02388 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | cofit | 35 | 99 |
| o | Castellaniella sp019104865 MT123 | ABCV34_RS09315 | | fumarylacetoacetate hydrolase family protein | insig. | 36 | 100 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_3547 | | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit/4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit | insig. | 39 | 94 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS28875 | | 5-oxo-1,2,5-tricarboxylic-3-penten acid decarboxylase | insig. | 38 | 88 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS15920 | | 4-hydroxyphenylacetate isomerase | insig. | 34 | 99 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS15920 | | 4-hydroxyphenylacetate isomerase | strong | 34 | 99 |
| | Pseudomonas simiae WCS417 | PS417_17830 | | 4-hydroxyphenylacetate isomerase | insig. | 36 | 95 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS04125 | | 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase | cofit | 33 | 95 |
| o | Serratia liquefaciens MT49 | IAI46_02725 | | fumarylacetoacetate hydrolase family protein | insig. | 36 | 94 |
| | Serratia liquefaciens MT49 | IAI46_02730 | | fumarylacetoacetate hydrolase family protein | insig. | 27 | 94 |
| | Variovorax sp. OAS795 | ABID97_RS28035 | | fumarylacetoacetate hydrolase family protein | insig. | 29 | 86 |
| | Xanthobacter sp. DMC5 | GFF2795 | | hypothetical protein | insig. | 29 | 80 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_1487 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 27 | 95 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS09310 | | fumarylacetoacetate hydrolase family protein | insig. | 28 | 82 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3278 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 27 | 64 |
| | Escherichia coli BL21 | ECD_04230 | | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | insig. | 25 | 79 |
| | Escherichia coli ECOR27 | NOLOHH_03715 | hpaG | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | insig. | 25 | 79 |
| | Escherichia coli ECRC62 | BNILDI_07885 | hpaG | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | insig. | 25 | 79 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03710 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | cofit | 25 | 79 |
| | Pectobacterium carotovorum WPP14 | HER17_RS11245 | | fumarylacetoacetate hydrolase family protein | cofit | 31 | 66 |
| | Azospirillum sp. SherDot2 | MPMX19_06799 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | insig. | 30 | 81 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_12120 | | 2-hydroxyhepta-2 4-diene-1 7-dioate isomerase | insig. | 26 | 81 |
| | Enterobacter sp. TBS_079 | MPMX20_00642 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | insig. | 27 | 64 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2290 | | Fumarylacetoacetate hydrolase family protein | insig. | 29 | 81 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_21230 | | 2-hydroxyhepta-2 4-diene-1 7-dioate isomerase | insig. | 30 | 65 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS28090 | | fumarylacetoacetate hydrolase family protein | insig. | 30 | 65 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS47550 | | fumarylacetoacetate hydrolase family protein | insig. | 30 | 65 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_3547 | | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit/4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit | insig. | 25 | 79 |
| | Variovorax sp. OAS795 | ABID97_RS03755 | | fumarylacetoacetate hydrolase family protein | sig. | 30 | 68 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2939 | | 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) | insig. | 28 | 64 |
| | Klebsiella michiganensis M5al | BWI76_RS03870 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 24 | 81 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS15925 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 27 | 81 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS15925 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | strong | 27 | 81 |
| | Escherichia coli BW25113 | b1180 | ycgM | predicted isomerase/hydrolase (NCBI) | insig. | 27 | 78 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1308 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 27 | 64 |
| | Sphingobium sp. HT1-2 | GFF1015 | | Fumarylacetoacetate hydrolase family protein | cofit | 28 | 74 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS04120 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | cofit | 28 | 68 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS28880 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 26 | 94 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03257 | | 5-carboxy-2-oxohept-3-enedioate decarboxylase HpaG2 subunit | no data | 26 | 94 |
| | Paraburkholderia graminis OAS925 | ABIE53_005228 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | sig. | 26 | 94 |
| | Escherichia coli BL21 | ECD_01155 | | putative isomerase/hydrolase | insig. | 27 | 78 |
| | Escherichia fergusonii Becca | EFB2_02751 | | putative protein YcgM | insig. | 27 | 78 |
| | Escherichia coli ECOR27 | NOLOHH_20780 | ycgM | fumarylacetoacetate hydrolase family protein | insig. | 27 | 78 |
| | Escherichia coli ECOR38 | HEPCGN_24690 | ycgM | fumarylacetoacetate hydrolase family protein | insig. | 27 | 78 |
| | Escherichia coli ECRC100 | OKFHMN_28240 | ycgM | fumarylacetoacetate hydrolase family protein | insig. | 27 | 78 |
| | Escherichia coli ECRC101 | MCAODC_21930 | ycgM | fumarylacetoacetate hydrolase family protein | insig. | 27 | 78 |
| | Escherichia coli ECRC102 | NIAGMN_27980 | ycgM | fumarylacetoacetate hydrolase family protein | insig. | 27 | 78 |
| | Escherichia coli ECRC62 | BNILDI_18940 | ycgM | fumarylacetoacetate hydrolase family protein | cofit | 27 | 78 |
| | Escherichia coli ECRC98 | JDDGAC_06270 | ycgM | fumarylacetoacetate hydrolase family protein | insig. | 27 | 78 |
| | Escherichia coli ECRC99 | KEDOAH_25255 | ycgM | fumarylacetoacetate hydrolase family protein | no data | 27 | 78 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_02511 | | putative protein YcgM | cofit | 27 | 78 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS07140 | | fumarylacetoacetate hydrolase family protein | insig. | 27 | 78 |
| | Variovorax sp. SCN45 | GFF5092 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 29 | 68 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS13530 | | fumarylacetoacetate hydrolase family protein | insig. | 27 | 82 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_25590 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 26 | 64 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02387 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | cofit | 26 | 64 |
| | Ralstonia solanacearum GMI1000 | RS_RS09200 | | FAA hydrolase family protein | sig. | 28 | 94 |
| | Dickeya dadantii 3937 | DDA3937_RS11195 | | fumarylacetoacetate hydrolase family protein | insig. | 29 | 75 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS12030 | | fumarylacetoacetate hydrolase family protein | insig. | 27 | 94 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS34380 | | fumarylacetoacetate hydrolase family protein | insig. | 25 | 94 |
| | Variovorax sp. SCN45 | GFF7103 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 27 | 80 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS07330 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase | insig. | 24 | 85 |
| | Bosea sp. OAE506 | ABIE41_RS22825 | | fumarylacetoacetate hydrolase family protein | insig. | 25 | 93 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1828 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 29 | 80 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF2814 | | FIG094199: Fumarylacetoacetate hydrolase | insig. | 27 | 66 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_0760 | | 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) | insig. | 26 | 78 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_25085 | | fumarylacetoacetate hydrolase family protein | insig. | 26 | 78 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c04530 | | ureidoglycolate lyase | insig. | 28 | 65 |
| | Pseudomonas orientalis W4I3 | QF045_RS12930 | | fumarylacetoacetate hydrolase family protein | insig. | 26 | 81 |
| | Dickeya dianthicola 67-19 | HGI48_RS11230 | | fumarylacetoacetate hydrolase family protein | insig. | 29 | 75 |
| | Dickeya dianthicola ME23 | DZA65_RS11575 | | fumarylacetoacetate hydrolase family protein | insig. | 29 | 75 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS27830 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 26 | 81 |
| | Rahnella sp. WP5 | EX31_RS10565 | | fumarylacetoacetate hydrolase family protein | insig. | 28 | 76 |