Conservation of cofitness between PP_1598 and PP_4891 in Pseudomonas putida KT2440

72 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_1598 regulatory intramembrane protein RIP zinc protease 1.0 PP_4891 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex 0.32 15
Pseudomonas fluorescens SBW25-INTG 0.83 PFLU_RS06310 sigma E protease regulator RseP 0.85 PFLU_RS02585 protease modulator HflC 0.48 23
Pseudomonas fluorescens SBW25 0.83 PFLU_RS06310 sigma E protease regulator RseP 0.85 PFLU_RS02585 protease modulator HflC 0.68 28
Pseudomonas simiae WCS417 0.83 PS417_06245 zinc metallopeptidase RseP 0.81 PS417_02505 membane protease HflC
Pseudomonas fluorescens FW300-N2E3 0.82 AO353_16495 zinc metallopeptidase RseP 0.87 AO353_13160 membrane protease HflC low > 101
Pseudomonas sp. RS175 0.82 PFR28_00403 Regulator of sigma-E protease RseP 0.82 PFR28_05124 Modulator of FtsH protease HflC low > 88
Pseudomonas fluorescens FW300-N2C3 0.82 AO356_06005 zinc metallopeptidase RseP 0.86 AO356_08640 membrane protease HflC low > 104
Pseudomonas fluorescens GW456-L13 0.81 PfGW456L13_4701 Membrane-associated zinc metalloprotease 0.86 PfGW456L13_151 HflC protein low > 87
Pseudomonas fluorescens FW300-N2E2 0.81 Pf6N2E2_3062 Membrane-associated zinc metalloprotease 0.86 Pf6N2E2_3611 HflC protein low > 103
Pseudomonas syringae pv. syringae B728a ΔmexB 0.81 Psyr_1350 site-2 protease, Metallo peptidase, MEROPS family M50B 0.88 Psyr_0575 protease FtsH subunit HflC low > 86
Pseudomonas syringae pv. syringae B728a 0.81 Psyr_1350 site-2 protease, Metallo peptidase, MEROPS family M50B 0.88 Psyr_0575 protease FtsH subunit HflC low > 86
Pseudomonas fluorescens FW300-N1B4 0.80 Pf1N1B4_3091 Membrane-associated zinc metalloprotease 0.87 Pf1N1B4_1409 HflC protein
Pseudomonas stutzeri RCH2 0.80 Psest_2835 RIP metalloprotease RseP 0.76 Psest_0686 Membrane protease subunits, stomatin/prohibitin homologs
Pseudomonas sp. S08-1 0.78 OH686_06450 RIP metalloprotease RseP 0.77 OH686_09455 HflC protein
Marinobacter adhaerens HP15 0.51 HP15_1173 membrane-associated zinc metalloprotease 0.55 HP15_2496 HflC low > 73
Alteromonas macleodii MIT1002 0.44 MIT1002_01011 Regulator of sigma E protease 0.48 MIT1002_03785 Modulator of FtsH protease HflC low > 70
Enterobacter asburiae PDN3 0.43 EX28DRAFT_3764 RIP metalloprotease RseP 0.36 EX28DRAFT_3372 HflC protein
Escherichia coli ECRC62 0.43 BNILDI_09150 rseP sigma E protease regulator RseP 0.38 BNILDI_06985 hflC protease modulator HflC
Escherichia coli HS(pFamp)R (ATCC 700891) 0.43 OHPLBJKB_03487 Regulator of sigma-E protease RseP 0.38 OHPLBJKB_03867 Modulator of FtsH protease HflC
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.43 GFF46 Intramembrane protease RasP/YluC, implicated in cell division based on FtsL cleavage 0.38 GFF828 HflC protein
Escherichia coli BL21 0.43 ECD_00174 inner membrane zinc RIP metalloprotease; RpoE activator, by degrading RseA; cleaved signal peptide endoprotease 0.38 ECD_04042 HflB protease modulator specific for phage lambda cII repressor
Enterobacter sp. TBS_079 0.43 MPMX20_00860 Regulator of sigma-E protease RseP 0.38 MPMX20_00456 Modulator of FtsH protease HflC
Escherichia coli ECRC102 0.43 NIAGMN_08025 rseP sigma E protease regulator RseP 0.38 NIAGMN_10090 hflC protease modulator HflC
Escherichia coli ECOR38 0.43 HEPCGN_08130 rseP sigma E protease regulator RseP 0.38 HEPCGN_10470 hflC protease modulator HflC
Escherichia fergusonii Becca 0.43 EFB2_03868 Regulator of sigma-E protease RseP 0.38 EFB2_04360 Modulator of FtsH protease HflC
Escherichia coli BW25113 0.43 b0176 yaeL zinc metallopeptidase (NCBI) 0.38 b4175 hflC modulator for HflB protease specific for phage lambda cII repressor (NCBI)
Escherichia coli ECRC99 0.43 KEDOAH_17980 rseP sigma E protease regulator RseP 0.38 KEDOAH_15915 hflC protease modulator HflC
Escherichia coli ECRC101 0.43 MCAODC_00690 rseP sigma E protease regulator RseP 0.38 MCAODC_02755 hflC protease modulator HflC
Escherichia coli ECOR27 0.43 NOLOHH_02520 rseP sigma E protease regulator RseP 0.38 NOLOHH_04505 hflC protease modulator HflC
Pantoea sp. MT58 0.43 IAI47_15495 sigma E protease regulator RseP 0.39 IAI47_02605 protease modulator HflC
Escherichia coli ECRC98 0.43 JDDGAC_13770 rseP sigma E protease regulator RseP 0.38 JDDGAC_15880 hflC protease modulator HflC
Escherichia coli ECRC101 0.43 OKFHMN_10175 rseP sigma E protease regulator RseP 0.38 OKFHMN_12240 hflC protease modulator HflC
Escherichia coli Nissle 1917 0.43 ECOLIN_RS00960 sigma E protease regulator RseP 0.38 ECOLIN_RS24245 protease modulator HflC
Serratia liquefaciens MT49 0.42 IAI46_20225 sigma E protease regulator RseP 0.39 IAI46_01640 protease modulator HflC
Erwinia tracheiphila SCR3 0.42 LU632_RS19930 rseP sigma E protease regulator RseP 0.38 LU632_RS02070 hflC protease modulator HflC low > 74
Shewanella oneidensis MR-1 0.42 SO1636 membrane-associated zinc metalloprotease, putative (NCBI ptt file) 0.46 SO0606 hflC hflC protein (NCBI ptt file)
Shewanella sp. ANA-3 0.42 Shewana3_2808 peptidase RseP (RefSeq) 0.46 Shewana3_0600 HflC protein (RefSeq)
Pectobacterium carotovorum WPP14 0.41 HER17_RS16300 sigma E protease regulator RseP 0.39 HER17_RS02600 protease modulator HflC low > 75
Shewanella loihica PV-4 0.41 Shew_2628 putative membrane-associated zinc metalloprotease (RefSeq) 0.45 Shew_0569 HflC protein (RefSeq)
Klebsiella michiganensis M5al 0.41 BWI76_RS05250 zinc metallopeptidase RseP 0.38 BWI76_RS02550 protease modulator HflC
Vibrio cholerae E7946 ATCC 55056 0.40 CSW01_11475 zinc metalloprotease 0.40 CSW01_01850 protease modulator HflC
Rahnella sp. WP5 0.40 EX31_RS13000 sigma E protease regulator RseP 0.37 EX31_RS08805 protease modulator HflC
Shewanella amazonensis SB2B 0.40 Sama_1146 membrane-associated zinc metalloprotease, putative (RefSeq) 0.45 Sama_3022 hflC protein (RefSeq) low > 62
Dickeya dianthicola ME23 0.40 DZA65_RS05490 sigma E protease regulator RseP 0.37 DZA65_RS19665 protease modulator HflC low > 75
Dickeya dadantii 3937 0.40 DDA3937_RS05150 sigma E protease regulator RseP 0.37 DDA3937_RS18595 protease modulator HflC
Dickeya dianthicola 67-19 0.40 HGI48_RS05150 sigma E protease regulator RseP 0.37 HGI48_RS18530 protease modulator HflC low > 71
Lysobacter sp. OAE881 0.37 ABIE51_RS06905 RIP metalloprotease RseP 0.38 ABIE51_RS06555 protease modulator HflC low > 62
Rhodanobacter sp. FW510-T8 0.37 OKGIIK_10175 rseP RIP metalloprotease RseP 0.46 OKGIIK_06645 hflC protease modulator HflC low > 52
Xanthomonas campestris pv. campestris strain 8004 0.37 Xcc-8004.3562.1 hypothetical protein 0.41 Xcc-8004.3954.1 HflC protein
Dechlorosoma suillum PS 0.36 Dsui_2687 RIP metalloprotease RseP 0.48 Dsui_3134 membrane protease subunit, stomatin/prohibitin
Castellaniella sp019104865 MT123 0.36 ABCV34_RS04075 RIP metalloprotease RseP 0.36 ABCV34_RS02665 protease modulator HflC
Rhodanobacter denitrificans FW104-10B01 0.36 LRK54_RS03290 RIP metalloprotease RseP 0.42 LRK54_RS00615 protease modulator HflC 0.82 32
Rhodanobacter denitrificans MT42 0.36 LRK55_RS03040 RIP metalloprotease RseP 0.42 LRK55_RS00385 protease modulator HflC
Dyella japonica UNC79MFTsu3.2 0.35 ABZR86_RS21620 RIP metalloprotease RseP 0.40 ABZR86_RS08350 protease modulator HflC
Variovorax sp. SCN45 0.33 GFF386 Membrane-associated zinc metalloprotease 0.33 GFF1003 HflC protein low > 127
Herbaspirillum seropedicae SmR1 0.33 HSERO_RS10910 peptidase 0.42 HSERO_RS14760 membrane protein low > 78
Kangiella aquimarina DSM 16071 0.33 B158DRAFT_1087 site-2 protease. Metallo peptidase. MEROPS family M50B 0.38 B158DRAFT_1955 HflC protein low > 40
Cupriavidus basilensis FW507-4G11 0.33 RR42_RS11840 zinc metalloprotease 0.42 RR42_RS13100 membrane protein
Burkholderia phytofirmans PsJN 0.32 BPHYT_RS12105 zinc metalloprotease 0.28 BPHYT_RS12540 membrane protein
Paraburkholderia bryophila 376MFSha3.1 0.32 H281DRAFT_00617 site-2 protease. Metallo peptidase. MEROPS family M50B 0.32 H281DRAFT_00524 protease FtsH subunit HflC
Variovorax sp. OAS795 0.32 ABID97_RS17135 RIP metalloprotease RseP 0.34 ABID97_RS14265 protease modulator HflC low > 91
Paraburkholderia sabiae LMG 24235 0.32 QEN71_RS06455 RIP metalloprotease RseP 0.27 QEN71_RS06015 protease modulator HflC low > 153
Paraburkholderia graminis OAS925 0.32 ABIE53_002496 regulator of sigma E protease 0.32 ABIE53_002734 membrane protease subunit HflC low > 113
Ralstonia solanacearum UW163 0.30 UW163_RS13740 RIP metalloprotease RseP 0.40 UW163_RS12780 protease modulator HflC
Ralstonia solanacearum IBSBF1503 0.30 RALBFv3_RS00410 RIP metalloprotease RseP 0.40 RALBFv3_RS15315 protease modulator HflC
Ralstonia solanacearum GMI1000 0.30 RS_RS07080 RIP metalloprotease RseP 0.40 RS_RS06125 protease modulator HflC
Ralstonia sp. UNC404CL21Col 0.29 ABZR87_RS11860 RIP metalloprotease RseP 0.39 ABZR87_RS10955 protease modulator HflC 0.31 59
Ralstonia solanacearum PSI07 0.29 RPSI07_RS17065 RIP metalloprotease RseP 0.41 RPSI07_RS18060 protease modulator HflC low > 81
Acidovorax sp. GW101-3H11 0.28 Ac3H11_425 Membrane-associated zinc metalloprotease 0.35 Ac3H11_1802 HflC protein
Hydrogenophaga sp. GW460-11-11-14-LB1 0.25 GFF4908 Membrane-associated zinc metalloprotease 0.30 GFF4855 HflC protein 0.66 40
Dinoroseobacter shibae DFL-12 0.23 Dshi_1498 putative membrane-associated zinc metalloprotease (RefSeq) 0.34 Dshi_2735 HflC protein (RefSeq) 0.38 12
Phaeobacter inhibens DSM 17395 0.20 PGA1_c14260 peptidase M50 0.35 PGA1_c23700 protein HflC low > 62
Echinicola vietnamensis KMM 6221, DSM 17526 0.15 Echvi_4671 RIP metalloprotease RseP 0.24 Echvi_2032 HflC protein

Not shown: 10 genomes with orthologs for PP_1598 only; 12 genomes with orthologs for PP_4891 only