Conservation of cofitness between PP_2215 and PP_2214 in Pseudomonas putida KT2440

57 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_2215 acetyl-CoA acetyltransferase 1.0 PP_2214 3-hydroxyacyl-CoA dehydrogenase type-2 0.64 2
Pseudomonas fluorescens FW300-N2E3 0.85 AO353_25685 acetyl-CoA:acetyl-CoA C-acetyltransferase / acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase (EC 2.3.1.9; EC 2.3.1.16) (from data) 0.74 AO353_25690 3-hydroxy-2-methylbutyryl-CoA dehydrogenase — —
Pseudomonas fluorescens GW456-L13 0.85 PfGW456L13_2982 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (from data) 0.74 PfGW456L13_2981 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) 0.36 12
Pseudomonas fluorescens SBW25-INTG 0.84 PFLU_RS14765 acetyl-CoA C-acyltransferase 0.80 PFLU_RS14760 SDR family NAD(P)-dependent oxidoreductase 0.61 7
Pseudomonas fluorescens SBW25 0.84 PFLU_RS14765 acetyl-CoA C-acyltransferase 0.80 PFLU_RS14760 SDR family NAD(P)-dependent oxidoreductase low > 109
Pseudomonas fluorescens FW300-N1B4 0.84 Pf1N1B4_4786 3-ketoacyl-CoA thiolase (EC 2.3.1.16) 0.72 Pf1N1B4_4785 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) — —
Pseudomonas sp. RS175 0.84 PFR28_01882 Acetyl-CoA acetyltransferase 0.76 PFR28_01881 putative oxidoreductase 0.64 8
Pseudomonas simiae WCS417 0.84 PS417_13855 acetyl-CoA acetyltransferase 0.75 PS417_13860 3-hydroxy-2-methylbutyryl-CoA dehydrogenase — —
Pseudomonas fluorescens FW300-N2E2 0.83 Pf6N2E2_1145 3-ketoacyl-CoA thiolase (EC 2.3.1.16) 0.74 Pf6N2E2_1144 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) — —
Pseudomonas fluorescens FW300-N2C3 0.83 AO356_26350 acetyl-CoA acetyltransferase 0.73 AO356_26345 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 0.51 2
Pseudomonas stutzeri RCH2 0.76 Psest_2446 acetyl-CoA acetyltransferases 0.68 Psest_2447 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) 0.26 8
Rhodopseudomonas palustris CGA009 0.75 TX73_011915 acetyl-CoA C-acetyltransferase 0.65 TX73_011910 3-hydroxyacyl-CoA dehydrogenase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.74 Psyr_3031 Thiolase 0.29 Psyr_4075 Short-chain dehydrogenase/reductase SDR low > 86
Pseudomonas syringae pv. syringae B728a 0.74 Psyr_3031 Thiolase 0.29 Psyr_4075 Short-chain dehydrogenase/reductase SDR low > 86
Pseudomonas sp. S08-1 0.74 OH686_00870 3-ketoacyl-CoA thiolase or Acetyl-CoA acetyltransferase 0.67 OH686_00865 3-hydroxyacyl-CoA dehydrogenase or 17hydroxysteroid dehydrogenase type 10 (HSD10)-like low > 80
Magnetospirillum magneticum AMB-1 0.69 AMB_RS18210 acetyl-CoA C-acyltransferase 0.51 AMB_RS18130 KR domain-containing protein low > 64
Paraburkholderia sabiae LMG 24235 0.68 QEN71_RS01125 acetyl-CoA C-acetyltransferase 0.60 QEN71_RS02810 3-hydroxyacyl-CoA dehydrogenase low > 153
Sinorhizobium meliloti 1021 0.67 SMa1450 thiolase 0.65 SMa1452 hypothetical protein low > 103
Paraburkholderia graminis OAS925 0.67 ABIE53_000590 acetyl-CoA C-acetyltransferase 0.64 ABIE53_005415 NAD(P)-dependent dehydrogenase (short-subunit alcohol dehydrogenase family) low > 113
Paraburkholderia bryophila 376MFSha3.1 0.67 H281DRAFT_02089 acetyl-CoA C-acetyltransferase 0.65 H281DRAFT_06131 NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family low > 103
Azospirillum sp. SherDot2 0.66 MPMX19_03936 Acetyl-CoA acetyltransferase 0.56 MPMX19_02389 putative oxidoreductase low > 112
Burkholderia phytofirmans PsJN 0.66 BPHYT_RS02230 acetyl-CoA acetyltransferase 0.61 BPHYT_RS15890 3-hydroxy-2-methylbutyryl-CoA dehydrogenase low > 109
Ralstonia solanacearum PSI07 0.65 RPSI07_RS22800 acetyl-CoA C-acyltransferase 0.58 RPSI07_RS12200 3-hydroxyacyl-CoA dehydrogenase low > 81
Dechlorosoma suillum PS 0.65 Dsui_0976 acetyl-CoA acetyltransferase 0.66 Dsui_1624 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein low > 51
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS06305 acetyl-CoA C-acetyltransferase 0.62 ABZR87_RS00745 3-hydroxyacyl-CoA dehydrogenase 0.55 6
Cupriavidus basilensis FW507-4G11 0.65 RR42_RS25380 acetyl-CoA acetyltransferase 0.59 RR42_RS03440 3-hydroxy-2-methylbutyryl-CoA dehydrogenase low > 128
Ralstonia solanacearum UW163 0.64 UW163_RS03065 acetyl-CoA C-acyltransferase 0.61 UW163_RS08530 3-hydroxyacyl-CoA dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.64 RALBFv3_RS10515 acetyl-CoA C-acyltransferase 0.61 RALBFv3_RS05095 3-hydroxyacyl-CoA dehydrogenase low > 76
Ralstonia solanacearum GMI1000 0.64 RS_RS01355 acetyl-CoA C-acyltransferase 0.61 RS_RS12705 3-hydroxyacyl-CoA dehydrogenase low > 80
Hydrogenophaga sp. GW460-11-11-14-LB1 0.64 GFF1723 3-ketoacyl-CoA thiolase (EC 2.3.1.16) 0.59 GFF3825 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) @ 17hydroxysteroid dehydrogenase type 10 (HSD10)-like 0.68 46
Agrobacterium fabrum C58 0.63 Atu3475 acetyl-CoA C-acetyltransferase 0.52 Atu1415 3-hydroxyacyl-CoA dehydrogenase type II low > 89
Acidovorax sp. GW101-3H11 0.63 Ac3H11_2994 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (from data) 0.59 Ac3H11_2606 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) @ 17hydroxysteroid dehydrogenase type 10 (HSD10)-like 0.85 1
Rhodospirillum rubrum S1H 0.62 Rru_A1946 Acetyl-CoA C-acetyltransferase (NCBI) 0.66 Rru_A1507 short-chain dehydrogenase/reductase SDR (NCBI) low > 58
Kangiella aquimarina DSM 16071 0.61 B158DRAFT_2511 acetyl-CoA acetyltransferases 0.48 B158DRAFT_1000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) low > 40
Variovorax sp. OAS795 0.60 ABID97_RS25195 acetyl-CoA C-acyltransferase 0.58 ABID97_RS10560 3-hydroxyacyl-CoA dehydrogenase 0.35 14
Variovorax sp. SCN45 0.60 GFF1993 3-ketoacyl-CoA thiolase (EC 2.3.1.16) 0.49 GFF2281 Short-chain dehydrogenase/reductase SDR 0.40 104
Herbaspirillum seropedicae SmR1 0.60 HSERO_RS04635 acetyl-CoA acetyltransferase 0.61 HSERO_RS04630 3-hydroxy-2-methylbutyryl-CoA dehydrogenase low > 78
Azospirillum brasilense Sp245 0.59 AZOBR_RS28180 acetyl-CoA acetyltransferase 0.54 AZOBR_RS26110 3-hydroxy-2-methylbutyryl-CoA dehydrogenase — —
Shewanella loihica PV-4 0.59 Shew_1667 acetyl-CoA acetyltransferase (RefSeq) 0.29 Shew_1673 fabG 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) low > 60
Castellaniella sp019104865 MT123 0.59 ABCV34_RS12360 acetyl-CoA C-acyltransferase 0.54 ABCV34_RS05365 3-hydroxyacyl-CoA dehydrogenase 0.98 18
Shewanella amazonensis SB2B 0.59 Sama_1375 Acetyl-CoA C-acetyltransferase (RefSeq) 0.29 Sama_1381 fabG 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) 0.55 4
Phaeobacter inhibens DSM 17395 0.59 PGA1_c33180 acetyl-CoA acetyltransferase 0.49 PGA1_c11320 3-hydroxyacyl-CoA dehydrogenase type-2 low > 62
Caulobacter crescentus NA1000 0.59 CCNA_00938 acetyl-CoA acetyltransferase 0.40 CCNA_00123 3-hydroxyacyl CoA dehydrogenase low > 66
Caulobacter crescentus NA1000 Δfur 0.59 CCNA_00938 acetyl-CoA acetyltransferase 0.40 CCNA_00123 3-hydroxyacyl CoA dehydrogenase low > 67
Brevundimonas sp. GW460-12-10-14-LB2 0.59 A4249_RS10470 acetyl-CoA C-acyltransferase 0.44 A4249_RS12825 SDR family oxidoreductase low > 48
Marinobacter adhaerens HP15 0.58 HP15_1009 acyl-CoA thiolase 0.53 HP15_1007 3-hydroxyacyl-CoA dehydrogenase type II low > 73
Sphingomonas koreensis DSMZ 15582 0.58 Ga0059261_1483 acetyl-CoA acetyltransferases 0.39 Ga0059261_2816 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) low > 68
Acinetobacter radioresistens SK82 0.58 MPMX26_02383 Acetyl-CoA acetyltransferase 0.54 MPMX26_01177 putative oxidoreductase — —
Alteromonas macleodii MIT1002 0.58 MIT1002_01671 Acetyl-CoA acetyltransferase 0.51 MIT1002_01862 Levodione reductase low > 70
Shewanella sp. ANA-3 0.57 Shewana3_2771 acetyl-CoA acetyltransferases (RefSeq) 0.28 Shewana3_2765 fabG 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) — —
Shewanella oneidensis MR-1 0.57 SO1677 atoB 3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16) (from data) 0.27 SO1683 3-hydroxy-2-methylbutyryl-CoA dehydrogenase IvdG (EC:1.1.1.178) (from data) low > 76
Dinoroseobacter shibae DFL-12 0.57 Dshi_0074 acetyl-CoA acetyltransferase (RefSeq) 0.50 Dshi_1700 short-chain dehydrogenase/reductase SDR (RefSeq) low > 64
Rhodanobacter sp. FW510-T8 0.53 OKGIIK_04025 paaJ acetyl-CoA C-acyltransferase 0.55 OKGIIK_09370 fabG 3-hydroxyacyl-CoA dehydrogenase low > 52
Rhodanobacter denitrificans FW104-10B01 0.53 LRK54_RS15265 acetyl-CoA C-acyltransferase 0.54 LRK54_RS02325 SDR family oxidoreductase 0.76 58
Rhodanobacter denitrificans MT42 0.53 LRK55_RS14980 acetyl-CoA C-acyltransferase 0.54 LRK55_RS02080 SDR family oxidoreductase low > 63
Lysobacter sp. OAE881 0.52 ABIE51_RS13145 acetyl-CoA C-acyltransferase 0.53 ABIE51_RS13215 SDR family NAD(P)-dependent oxidoreductase — —
Dyella japonica UNC79MFTsu3.2 0.51 ABZR86_RS20570 acetyl-CoA C-acyltransferase 0.55 ABZR86_RS08630 SDR family NAD(P)-dependent oxidoreductase low > 74
Xanthomonas campestris pv. campestris strain 8004 0.50 Xcc-8004.3647.1 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9) 0.49 Xcc-8004.2924.1 Short-chain dehydrogenase/reductase SDR 0.63 7

Not shown: 5 genomes with orthologs for PP_2215 only; 2 genomes with orthologs for PP_2214 only