Conservation of cofitness between MPMX19_00336 and MPMX19_02000 in Azospirillum sp. SherDot2

83 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Azospirillum sp. SherDot2 1.0 MPMX19_00336 Phosphomethylpyrimidine synthase 1.0 MPMX19_02000 Aspartate-semialdehyde dehydrogenase 2 0.84 1
Azospirillum brasilense Sp245 0.80 AZOBR_RS07940 phosphomethylpyrimidine synthase 0.69 AZOBR_RS13975 aspartate-semialdehyde dehydrogenase low > 97
Sinorhizobium meliloti 1021 0.75 SM_b20615 thiamine biosynthesis protein ThiC 0.63 SMc04410 aspartate-semialdehyde dehydrogenase — —
Magnetospirillum magneticum AMB-1 0.75 AMB_RS01125 phosphomethylpyrimidine synthase 0.72 AMB_RS03035 aspartate-semialdehyde dehydrogenase — —
Agrobacterium fabrum C58 0.74 Atu2569 thiamine biosynthesis protein 0.63 Atu2490 aspartate-semialdehyde dehydrogenase — —
Dinoroseobacter shibae DFL-12 0.74 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) 0.61 Dshi_3240 aspartate-semialdehyde dehydrogenase (RefSeq) — —
Sphingomonas koreensis DSMZ 15582 0.74 Ga0059261_2424 hydroxymethylpyrimidine synthase 0.64 Ga0059261_4003 aspartate-semialdehyde dehydrogenase (peptidoglycan organisms) — —
Phaeobacter inhibens DSM 17395 0.73 PGA1_c09110 thiamine biosynthesis protein ThiC 0.61 PGA1_c31480 aspartate-semialdehyde dehydrogenase Asd — —
Caulobacter crescentus NA1000 0.73 CCNA_02109 thiamine biosynthesis protein thiC 0.62 CCNA_00253 aspartate-semialdehyde dehydrogenase low > 66
Xanthobacter sp. DMC5 0.73 GFF257 Phosphomethylpyrimidine synthase 0.66 GFF2437 Aspartate-semialdehyde dehydrogenase 2 — —
Caulobacter crescentus NA1000 Δfur 0.73 CCNA_02109 thiamine biosynthesis protein thiC 0.62 CCNA_00253 aspartate-semialdehyde dehydrogenase low > 67
Brevundimonas sp. GW460-12-10-14-LB2 0.72 A4249_RS15715 phosphomethylpyrimidine synthase ThiC 0.60 A4249_RS12690 aspartate-semialdehyde dehydrogenase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.72 CA264_20435 phosphomethylpyrimidine synthase ThiC 0.39 CA264_18890 aspartate-semialdehyde dehydrogenase — —
Kangiella aquimarina DSM 16071 0.72 B158DRAFT_0295 hydroxymethylpyrimidine synthase 0.49 B158DRAFT_1481 aspartate-semialdehyde dehydrogenase (peptidoglycan organisms) — —
Pseudomonas sp. BP01 0.71 JOY50_RS10065 thiC phosphomethylpyrimidine synthase ThiC 0.28 JOY50_RS16605 aspartate-semialdehyde dehydrogenase low > 84
Mucilaginibacter yixingensis YX-36 DSM 26809 0.71 ABZR88_RS08840 phosphomethylpyrimidine synthase ThiC 0.42 ABZR88_RS18675 aspartate-semialdehyde dehydrogenase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.71 Echvi_3567 thiamine biosynthesis protein ThiC 0.39 Echvi_0713 aspartate-semialdehyde dehydrogenase (peptidoglycan organisms) — —
Pseudomonas putida KT2440 0.71 PP_4922 Phosphomethylpyrimidine synthase 0.27 PP_1992 aspartate-semialdehyde dehydrogenase low > 96
Rhodopseudomonas palustris CGA009 0.71 TX73_018540 phosphomethylpyrimidine synthase ThiC 0.66 TX73_001190 aspartate-semialdehyde dehydrogenase — —
Pseudomonas sp. RS175 0.71 PFR28_05091 Phosphomethylpyrimidine synthase 0.31 PFR28_02819 USG-1 protein low > 88
Cellulophaga baltica 18 0.70 M666_RS10600 phosphomethylpyrimidine synthase ThiC 0.36 M666_RS04365 aspartate-semialdehyde dehydrogenase — —
Bosea sp. OAE506 0.70 ABIE41_RS02770 phosphomethylpyrimidine synthase ThiC 0.65 ABIE41_RS08445 aspartate-semialdehyde dehydrogenase — —
Pedobacter sp. GW460-11-11-14-LB5 0.70 CA265_RS20165 phosphomethylpyrimidine synthase ThiC 0.42 CA265_RS15395 aspartate-semialdehyde dehydrogenase — —
Pseudomonas fluorescens FW300-N2E2 0.70 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.31 Pf6N2E2_68 Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) low > 103
Pseudomonas fluorescens GW456-L13 0.70 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.30 PfGW456L13_3943 Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) low > 87
Pseudomonas fluorescens FW300-N2C3 0.70 AO356_08810 thiamine biosynthesis protein ThiC 0.30 AO356_21425 aspartate-semialdehyde dehydrogenase low > 104
Rhodanobacter sp. FW510-T8 0.70 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC 0.49 OKGIIK_04815 asd aspartate-semialdehyde dehydrogenase — —
Pseudomonas sp. S08-1 0.70 OH686_15885 phosphomethylpyrimidine synthase 0.27 OH686_04460 Aspartate-semialdehyde dehydrogenase low > 80
Pseudomonas stutzeri RCH2 0.70 Psest_0477 thiamine biosynthesis protein ThiC 0.23 Psest_2587 Aspartate-semialdehyde dehydrogenase low > 67
Pseudomonas fluorescens FW300-N2E3 0.70 AO353_13010 thiamine biosynthesis protein ThiC 0.30 AO353_20645 aspartate-semialdehyde dehydrogenase low > 101
Pseudomonas aeruginosa PA14 0.70 IKLFDK_28675 phosphomethylpyrimidine synthase ThiC 0.25 IKLFDK_15855 aspartate-semialdehyde dehydrogenase low > 101
Pseudomonas sp. DMC3 0.70 GFF3183 Phosphomethylpyrimidine synthase 0.30 GFF790 USG-1 protein low > 89
Pseudomonas fluorescens SBW25-INTG 0.70 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.29 PFLU_RS20555 aspartate-semialdehyde dehydrogenase low > 109
Pseudomonas fluorescens SBW25 0.70 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.29 PFLU_RS20555 aspartate-semialdehyde dehydrogenase low > 109
Dyella japonica UNC79MFTsu3.2 0.70 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC 0.50 ABZR86_RS08030 aspartate-semialdehyde dehydrogenase — —
Pseudomonas sp. SVBP6 0.70 COO64_RS17755 thiC phosphomethylpyrimidine synthase ThiC 0.28 COO64_RS05640 aspartate-semialdehyde dehydrogenase low > 93
Enterobacter sp. TBS_079 0.70 MPMX20_00217 Phosphomethylpyrimidine synthase 0.33 MPMX20_03254 USG-1 protein low > 85
Pseudomonas syringae pv. syringae B728a 0.70 Psyr_0544 hydroxymethylpyrimidine synthase 0.29 Psyr_1660 Aspartate-semialdehyde dehydrogenase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.70 Psyr_0544 hydroxymethylpyrimidine synthase 0.29 Psyr_1660 Aspartate-semialdehyde dehydrogenase low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.70 GFF4198 Thiamin biosynthesis protein ThiC 0.33 GFF1935 Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) low > 78
Enterobacter asburiae PDN3 0.70 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.31 EX28DRAFT_0285 Aspartate-semialdehyde dehydrogenase low > 76
Pseudomonas simiae WCS417 0.70 PS417_02355 thiamine biosynthesis protein ThiC 0.28 PS417_18575 aspartate-semialdehyde dehydrogenase low > 88
Escherichia coli ECRC62 0.70 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.33 BNILDI_13220 usg aspartate-semialdehyde dehydrogenase low > 75
Rhodanobacter sp000427505 FW510-R12 0.70 LRK53_RS03795 phosphomethylpyrimidine synthase ThiC 0.50 LRK53_RS08320 aspartate-semialdehyde dehydrogenase — —
Escherichia coli ECOR27 0.70 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 0.33 NOLOHH_14300 usg aspartate-semialdehyde dehydrogenase low > 75
Escherichia coli ECOR38 0.70 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.33 HEPCGN_21870 usg aspartate-semialdehyde dehydrogenase low > 87
Escherichia coli BW25113 0.70 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.33 b2319 usg hypothetical protein (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.70 OHPLBJKB_04056 Phosphomethylpyrimidine synthase 0.33 OHPLBJKB_01386 USG-1 protein low > 73
Escherichia coli BL21 0.70 ECD_03871 phosphomethylpyrimidine synthase 0.33 ECD_02244 putative semialdehyde dehydrogenase low > 61
Escherichia coli ECRC101 0.69 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.33 MCAODC_13705 usg aspartate-semialdehyde dehydrogenase low > 87
Escherichia coli ECRC98 0.69 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC 0.33 JDDGAC_26625 usg aspartate-semialdehyde dehydrogenase — —
Escherichia fergusonii Becca 0.69 EFB2_04617 Phosphomethylpyrimidine synthase 0.34 EFB2_01539 USG-1 protein low > 86
Pseudomonas fluorescens FW300-N1B4 0.69 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.29 Pf1N1B4_10 Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) low > 87
Escherichia coli ECRC102 0.69 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC 0.33 NIAGMN_20440 usg aspartate-semialdehyde dehydrogenase — —
Escherichia coli ECRC99 0.69 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC 0.33 KEDOAH_05530 usg aspartate-semialdehyde dehydrogenase — —
Escherichia coli Nissle 1917 0.69 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.34 ECOLIN_RS13440 aspartate-semialdehyde dehydrogenase low > 55
Escherichia coli ECRC100 0.69 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.33 OKFHMN_22665 usg aspartate-semialdehyde dehydrogenase low > 80
Lysobacter sp. OAE881 0.69 ABIE51_RS17515 phosphomethylpyrimidine synthase ThiC 0.48 ABIE51_RS08235 aspartate-semialdehyde dehydrogenase — —
Pectobacterium carotovorum WPP14 0.69 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.33 HER17_RS06985 aspartate-semialdehyde dehydrogenase low > 75
Erwinia amylovora T8 0.69 OLJFJH_06740 phosphomethylpyrimidine synthase ThiC 0.30 OLJFJH_11235 aspartate-semialdehyde dehydrogenase low > 58
Xanthomonas campestris pv. campestris strain 8004 0.69 Xcc-8004.1066.1 hypothetical protein 0.48 Xcc-8004.1957.1 Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) — —
Dickeya dadantii 3937 0.69 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.34 DDA3937_RS14470 aspartate-semialdehyde dehydrogenase low > 74
Erwinia tracheiphila SCR3 0.69 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC 0.30 LU632_RS07820 aspartate-semialdehyde dehydrogenase low > 74
Shewanella loihica PV-4 0.69 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.48 Shew_2308 aspartate-semialdehyde dehydrogenase (RefSeq) — —
Alteromonas macleodii MIT1002 0.68 MIT1002_00097 Phosphomethylpyrimidine synthase 0.46 MIT1002_02531 Aspartate-semialdehyde dehydrogenase 2 low > 70
Klebsiella michiganensis M5al 0.68 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.32 BWI76_RS20385 aspartate-semialdehyde dehydrogenase low > 92
Rahnella sp. WP5 0.68 EX31_RS16815 phosphomethylpyrimidine synthase ThiC 0.34 EX31_RS19605 aspartate-semialdehyde dehydrogenase low > 89
Rhodospirillum rubrum S1H 0.68 Rru_A2008 Thiamine biosynthesis protein ThiC (NCBI) 0.73 Rru_A1196 Aspartate-semialdehyde dehydrogenase, USG-1 related (NCBI) — —
Pantoea sp. MT58 0.68 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.31 IAI47_06240 aspartate-semialdehyde dehydrogenase low > 76
Dickeya dianthicola 67-19 0.68 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.34 HGI48_RS14440 aspartate-semialdehyde dehydrogenase — —
Shewanella amazonensis SB2B 0.68 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.48 Sama_2152 aspartate-semialdehyde dehydrogenase (RefSeq) — —
Serratia liquefaciens MT49 0.68 IAI46_01320 phosphomethylpyrimidine synthase ThiC 0.33 IAI46_17845 aspartate-semialdehyde dehydrogenase low > 86
Dickeya dianthicola ME23 0.68 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.34 DZA65_RS15375 aspartate-semialdehyde dehydrogenase low > 75
Shewanella sp. ANA-3 0.66 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.47 Shewana3_1477 aspartate semialdehyde dehydrogenase (RefSeq) — —
Shewanella oneidensis MR-1 0.66 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.47 SO3070 asd aspartate semialdehyde dehydrogenese (NCBI ptt file) — —
Vibrio cholerae E7946 ATCC 55056 0.66 CSW01_00335 phosphomethylpyrimidine synthase 0.48 CSW01_10520 Aspartate-semialdehyde dehydrogenase 2 low > 62
Bacteroides ovatus ATCC 8483 0.60 BACOVA_02358 thiamine biosynthesis protein ThiC 0.44 BACOVA_03470 aspartate-semialdehyde dehydrogenase — —
Phocaeicola vulgatus CL09T03C04 0.60 HMPREF1058_RS03280 phosphomethylpyrimidine synthase ThiC 0.44 HMPREF1058_RS00210 aspartate-semialdehyde dehydrogenase — —
Phocaeicola dorei CL03T12C01 0.60 ABI39_RS17760 phosphomethylpyrimidine synthase ThiC 0.44 ABI39_RS01110 aspartate-semialdehyde dehydrogenase — —
Bacteroides thetaiotaomicron VPI-5482 0.60 BT0650 thiamine biosynthesis protein ThiC (NCBI ptt file) 0.44 BT3636 aspartate-semialdehyde dehydrogenase (NCBI ptt file) — —
Bacteroides stercoris CC31F 0.59 HMPREF1181_RS14685 phosphomethylpyrimidine synthase ThiC 0.44 HMPREF1181_RS03115 aspartate-semialdehyde dehydrogenase — —
Mycobacterium tuberculosis H37Rv 0.59 Rv0423c Probable thiamine biosynthesis protein ThiC 0.38 Rv3708c Aspartate-semialdehyde dehydrogenase Asd (ASA dehydrogenase) (ASADH) (aspartic semialdehyde dehydrogenase) (L-aspartate-beta-semialdehyde dehydrogenase) — —
Parabacteroides merdae CL09T00C40 0.57 HMPREF1078_RS03485 phosphomethylpyrimidine synthase ThiC 0.43 HMPREF1078_RS05255 aspartate-semialdehyde dehydrogenase — —
Synechococcus elongatus PCC 7942 0.46 Synpcc7942_1096 thiC thiamine biosynthesis protein ThiC 0.44 Synpcc7942_1848 asd aspartate-semialdehyde dehydrogenase — —

Not shown: 21 genomes with orthologs for MPMX19_00336 only; 8 genomes with orthologs for MPMX19_02000 only