Conservation of cofitness between GFF4626 and GFF1327 in Hydrogenophaga sp. GW460-11-11-14-LB1

67 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Hydrogenophaga sp. GW460-11-11-14-LB1 1.0 GFF4626 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 1.0 GFF1327 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) 0.57 17
Variovorax sp. SCN45 0.83 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.87 GFF5332 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) low > 127
Variovorax sp. OAS795 0.81 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC 0.87 ABID97_RS23225 glutamate synthase-related protein low > 91
Acidovorax sp. GW101-3H11 0.81 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.87 Ac3H11_4710 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) 0.74 41
Castellaniella sp019104865 MT123 0.69 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC 0.70 ABCV34_RS11150 glutamate synthase-related protein 0.47 5
Herbaspirillum seropedicae SmR1 0.68 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC 0.76 HSERO_RS19595 glutamate synthase 0.40 23
Paraburkholderia sabiae LMG 24235 0.68 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC 0.75 QEN71_RS28010 glutamate synthase-related protein 0.70 80
Dyella japonica UNC79MFTsu3.2 0.67 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC 0.34 ABZR86_RS16795 glutamate synthase large subunit low > 74
Paraburkholderia bryophila 376MFSha3.1 0.67 H281DRAFT_00395 hydroxymethylpyrimidine synthase 0.75 H281DRAFT_05620 glutamate synthase (NADH) large subunit 0.49 29
Marinobacter adhaerens HP15 0.67 HP15_453 thiamine biosynthesis protein thiC 0.37 HP15_482 glutamate synthase subunit alpha — —
Pseudomonas stutzeri RCH2 0.67 Psest_0477 thiamine biosynthesis protein ThiC 0.36 Psest_3711 Glutamate synthase domain 2 low > 67
Rhodanobacter sp. FW510-T8 0.67 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC 0.72 OKGIIK_15200 Glutamate synthase subunit alpha low > 52
Dechlorosoma suillum PS 0.67 Dsui_0422 thiamine biosynthesis protein ThiC 0.66 Dsui_1096 glutamate synthase family protein — —
Burkholderia phytofirmans PsJN 0.67 BPHYT_RS13220 phosphomethylpyrimidine synthase 0.75 BPHYT_RS17855 glutamate synthase 0.65 40
Pseudomonas fluorescens FW300-N2E2 0.67 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.36 Pf6N2E2_3752 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) low > 103
Pseudomonas fluorescens SBW25-INTG 0.67 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.36 PFLU_RS02045 glutamate synthase large subunit low > 109
Pseudomonas fluorescens SBW25 0.67 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.36 PFLU_RS02045 glutamate synthase large subunit low > 109
Pseudomonas putida KT2440 0.67 PP_4922 Phosphomethylpyrimidine synthase 0.36 PP_5076 L-glutamate synthase(NADPH) alpha subunit 0.33 71
Pseudomonas fluorescens FW300-N2C3 0.67 AO356_08810 thiamine biosynthesis protein ThiC 0.36 AO356_09375 glutamate synthase low > 104
Pedobacter sp. GW460-11-11-14-LB5 0.67 CA265_RS20165 phosphomethylpyrimidine synthase ThiC 0.48 CA265_RS08700 glutamate synthase large subunit low > 88
Pseudomonas sp. RS175 0.67 PFR28_05091 Phosphomethylpyrimidine synthase 0.36 PFR28_05015 Glutamate synthase [NADPH] large chain low > 88
Pseudomonas sp. S08-1 0.67 OH686_15885 phosphomethylpyrimidine synthase 0.36 OH686_10005 Glutamate synthase [NADPH] large chain low > 80
Pseudomonas fluorescens GW456-L13 0.67 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.36 PfGW456L13_272 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) low > 87
Mucilaginibacter yixingensis YX-36 DSM 26809 0.67 ABZR88_RS08840 phosphomethylpyrimidine synthase ThiC 0.48 ABZR88_RS06905 glutamate synthase large subunit low > 71
Pseudomonas simiae WCS417 0.67 PS417_02355 thiamine biosynthesis protein ThiC 0.36 PS417_02000 glutamate synthase low > 88
Pseudomonas fluorescens FW300-N1B4 0.67 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.35 Pf1N1B4_1534 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) low > 87
Pseudomonas fluorescens FW300-N2E3 0.66 AO353_13010 thiamine biosynthesis protein ThiC 0.36 AO353_12515 glutamate synthase low > 101
Pseudomonas syringae pv. syringae B728a ΔmexB 0.66 Psyr_0544 hydroxymethylpyrimidine synthase 0.36 Psyr_0411 glutamate synthase (NADPH) large subunit low > 86
Pseudomonas syringae pv. syringae B728a 0.66 Psyr_0544 hydroxymethylpyrimidine synthase 0.36 Psyr_0411 glutamate synthase (NADPH) large subunit 0.70 11
Xanthomonas campestris pv. campestris strain 8004 0.65 Xcc-8004.1066.1 hypothetical protein 0.36 Xcc-8004.44.1 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) 0.63 36
Echinicola vietnamensis KMM 6221, DSM 17526 0.65 Echvi_3567 thiamine biosynthesis protein ThiC 0.45 Echvi_1244 Glutamate synthase domain 2 low > 79
Acinetobacter radioresistens SK82 0.65 MPMX26_00180 Phosphomethylpyrimidine synthase 0.35 MPMX26_02808 Glutamate synthase [NADPH] large chain low > 36
Caulobacter crescentus NA1000 0.65 CCNA_02109 thiamine biosynthesis protein thiC 0.35 CCNA_03722 glutamate synthase (NADPH) large chain GltB low > 66
Caulobacter crescentus NA1000 Δfur 0.65 CCNA_02109 thiamine biosynthesis protein thiC 0.35 CCNA_03722 glutamate synthase (NADPH) large chain GltB low > 67
Rahnella sp. WP5 0.64 EX31_RS16815 phosphomethylpyrimidine synthase ThiC 0.38 EX31_RS12515 glutamate synthase large subunit low > 89
Dinoroseobacter shibae DFL-12 0.64 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) 0.35 Dshi_0002 Glutamate synthase (ferredoxin) (RefSeq) — —
Sinorhizobium meliloti 1021 0.64 SM_b20615 thiamine biosynthesis protein ThiC 0.58 SMc04028 glutamate synthase low > 103
Enterobacter sp. TBS_079 0.64 MPMX20_00217 Phosphomethylpyrimidine synthase 0.37 MPMX20_04126 Glutamate synthase [NADPH] large chain low > 85
Dickeya dadantii 3937 0.64 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.37 DDA3937_RS01665 glutamate synthase large subunit 0.84 12
Brevundimonas sp. GW460-12-10-14-LB2 0.64 A4249_RS15715 phosphomethylpyrimidine synthase ThiC 0.34 A4249_RS16105 glutamate synthase large subunit low > 48
Agrobacterium fabrum C58 0.64 Atu2569 thiamine biosynthesis protein 0.57 Atu3784 glutamate synthase large subunit 0.76 17
Alteromonas macleodii MIT1002 0.64 MIT1002_00097 Phosphomethylpyrimidine synthase 0.37 MIT1002_03139 Glutamate synthase [NADPH] large chain precursor low > 70
Erwinia tracheiphila SCR3 0.64 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC 0.37 LU632_RS21315 gltB glutamate synthase large subunit low > 74
Sphingomonas koreensis DSMZ 15582 0.64 Ga0059261_2424 hydroxymethylpyrimidine synthase 0.38 Ga0059261_1800 Glutamate synthase domain 2 low > 68
Pectobacterium carotovorum WPP14 0.63 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.38 HER17_RS19910 glutamate synthase large subunit low > 75
Serratia liquefaciens MT49 0.63 IAI46_01320 phosphomethylpyrimidine synthase ThiC 0.38 IAI46_22345 glutamate synthase large subunit low > 86
Rhodopseudomonas palustris CGA009 0.63 TX73_018540 phosphomethylpyrimidine synthase ThiC 0.56 TX73_004590 glutamate synthase large subunit — —
Dickeya dianthicola 67-19 0.63 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.37 HGI48_RS01560 glutamate synthase large subunit 0.76 59
Magnetospirillum magneticum AMB-1 0.63 AMB_RS01125 phosphomethylpyrimidine synthase 0.37 AMB_RS02685 glutamate synthase large subunit — —
Shewanella loihica PV-4 0.63 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.37 Shew_1032 gltB glutamate synthase subunit alpha (RefSeq) low > 60
Bosea sp. OAE506 0.63 ABIE41_RS02770 phosphomethylpyrimidine synthase ThiC 0.57 ABIE41_RS08565 glutamate synthase large subunit low > 77
Dickeya dianthicola ME23 0.63 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.37 DZA65_RS01635 glutamate synthase large subunit 0.78 23
Shewanella amazonensis SB2B 0.63 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.37 Sama_0857 gltB glutamate synthase subunit alpha (RefSeq) low > 62
Ralstonia sp. UNC404CL21Col 0.63 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC 0.75 ABZR87_RS02570 glutamate synthase-related protein 0.52 76
Ralstonia solanacearum IBSBF1503 0.63 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC 0.76 RALBFv3_RS06915 glutamate synthase subunit alpha low > 76
Ralstonia solanacearum PSI07 0.63 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC 0.76 RPSI07_RS10320 glutamate synthase subunit alpha low > 81
Ralstonia solanacearum UW163 0.63 UW163_RS03640 phosphomethylpyrimidine synthase ThiC 0.76 UW163_RS06700 glutamate synthase subunit alpha — —
Vibrio cholerae E7946 ATCC 55056 0.62 CSW01_00335 phosphomethylpyrimidine synthase 0.46 CSW01_12020 glutamate synthase large subunit low > 62
Ralstonia solanacearum GMI1000 0.62 RS_RS00555 phosphomethylpyrimidine synthase 0.75 RS_RS14860 glutamate synthase subunit alpha 0.51 23
Shewanella sp. ANA-3 0.62 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.37 Shewana3_3050 gltB glutamate synthase subunit alpha (RefSeq) low > 73
Shewanella oneidensis MR-1 0.62 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.37 SO1325 gltB glutamate synthase, large subunit (NCBI ptt file) low > 76
Rhodospirillum rubrum S1H 0.60 Rru_A2008 Thiamine biosynthesis protein ThiC (NCBI) 0.39 Rru_A0019 Glutamate synthase (ferredoxin) (NCBI) — —
Bacteroides thetaiotaomicron VPI-5482 0.54 BT0650 thiamine biosynthesis protein ThiC (NCBI ptt file) 0.43 BT0553 glutamate synthase, large subunit (NCBI ptt file) low > 81
Phocaeicola dorei CL03T12C01 0.54 ABI39_RS17760 phosphomethylpyrimidine synthase ThiC 0.44 ABI39_RS20685 glutamate synthase large subunit low > 72
Phocaeicola vulgatus CL09T03C04 0.54 HMPREF1058_RS03280 phosphomethylpyrimidine synthase ThiC 0.43 HMPREF1058_RS06920 glutamate synthase large subunit low > 67
Bacteroides ovatus ATCC 8483 0.54 BACOVA_02358 thiamine biosynthesis protein ThiC 0.44 BACOVA_03756 class II glutamine amidotransferase low > 94
Bacteroides stercoris CC31F 0.53 HMPREF1181_RS14685 phosphomethylpyrimidine synthase ThiC 0.43 HMPREF1181_RS16055 glutamate synthase large subunit low > 56
Mycobacterium tuberculosis H37Rv 0.52 Rv0423c Probable thiamine biosynthesis protein ThiC 0.47 Rv3859c Probable ferredoxin-dependent glutamate synthase [NADPH] (large subunit) GltB (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate synthase) (glutamate synthase (NADH))(NADPH-GOGAT) — —

Not shown: 5 genomes with orthologs for GFF4626 only; 25 genomes with orthologs for GFF1327 only