Conservation of cofitness between ECD_03708 and ECD_04120 in Escherichia coli BL21

67 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_03708 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 1.0 ECD_04120 ornithine carbamoyltransferase 1 0.91 25
Escherichia coli Nissle 1917 1.00 ECOLIN_RS21980 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.95 ECOLIN_RS24665 ornithine carbamoyltransferase low > 55
Escherichia coli BW25113 1.00 b3829 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI) 0.99 b4254 argI ornithine carbamoyltransferase 1 (NCBI) low > 76
Escherichia fergusonii Becca 1.00 EFB2_04808 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.95 EFB2_04281 Ornithine carbamoyltransferase subunit I low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_04222 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1.00 OHPLBJKB_03782 Ornithine carbamoyltransferase subunit I low > 73
Escherichia coli ECOR27 0.99 NOLOHH_06455 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 NOLOHH_04090 argF ornithine carbamoyltransferase low > 75
Escherichia coli ECRC62 0.99 BNILDI_05075 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 BNILDI_07425 argF ornithine carbamoyltransferase 0.98 20
Escherichia coli ECOR38 0.99 HEPCGN_13025 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.95 HEPCGN_10025 argF ornithine carbamoyltransferase 0.97 24
Escherichia coli ECRC99 0.99 KEDOAH_13825 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 KEDOAH_16320 argF ornithine carbamoyltransferase — —
Escherichia coli ECRC98 0.99 JDDGAC_17950 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 JDDGAC_15475 argF ornithine carbamoyltransferase low > 86
Escherichia coli ECRC100 0.99 OKFHMN_14325 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 OKFHMN_11835 argF ornithine carbamoyltransferase 0.93 51
Escherichia coli ECRC101 0.99 MCAODC_04830 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 MCAODC_02340 argF ornithine carbamoyltransferase 0.92 29
Escherichia coli ECRC102 0.99 NIAGMN_12080 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 NIAGMN_09685 argF ornithine carbamoyltransferase — —
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4494 methionine synthase (B12-independent) (EC 2.1.1.14) 0.90 EX28DRAFT_3461 ornithine carbamoyltransferase 0.69 49
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF254 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.91 GFF940 Ornithine carbamoyltransferase (EC 2.1.3.3) low > 78
Klebsiella michiganensis M5al 0.94 BWI76_RS01280 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.91 BWI76_RS03010 ornithine carbamoyltransferase 0.28 39
Enterobacter sp. TBS_079 0.94 MPMX20_04451 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.90 MPMX20_00556 Ornithine carbamoyltransferase subunit F low > 85
Pectobacterium carotovorum WPP14 0.86 HER17_RS20685 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.85 HER17_RS19500 ornithine carbamoyltransferase low > 75
Dickeya dadantii 3937 0.85 DDA3937_RS20380 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.83 DDA3937_RS01940 ornithine carbamoyltransferase 0.56 14
Dickeya dianthicola ME23 0.85 DZA65_RS00875 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.82 DZA65_RS01985 ornithine carbamoyltransferase low > 75
Dickeya dianthicola 67-19 0.85 HGI48_RS00820 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.82 HGI48_RS01915 ornithine carbamoyltransferase 0.81 39
Erwinia tracheiphila SCR3 0.84 LU632_RS24030 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.83 LU632_RS20900 argF ornithine carbamoyltransferase low > 74
Serratia liquefaciens MT49 0.84 IAI46_01035 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.81 IAI46_02320 ornithine carbamoyltransferase 0.76 21
Rahnella sp. WP5 0.83 EX31_RS14710 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.82 EX31_RS12825 ornithine carbamoyltransferase low > 89
Pantoea sp. MT58 0.83 IAI47_18310 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.82 IAI47_16830 ornithine carbamoyltransferase low > 76
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_5472 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.58 Pf6N2E2_2909 Ornithine carbamoyltransferase (EC 2.1.3.3) low > 103
Pseudomonas fluorescens FW300-N1B4 0.62 Pf1N1B4_783 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.59 Pf1N1B4_616 Ornithine carbamoyltransferase (EC 2.1.3.3) low > 87
Pseudomonas sp. RS175 0.61 PFR28_03477 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.58 PFR28_02179 Ornithine carbamoyltransferase, catabolic low > 88
Pseudomonas fluorescens FW300-N2E3 0.61 AO353_16215 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.59 AO353_03475 ornithine carbamoyltransferase low > 101
Pseudomonas fluorescens FW300-N2C3 0.61 AO356_17740 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.59 AO356_05275 ornithine carbamoyltransferase low > 104
Pseudomonas stutzeri RCH2 0.60 Psest_1452 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 0.60 Psest_0271 ornithine carbamoyltransferase low > 67
Vibrio cholerae E7946 ATCC 55056 0.60 CSW01_08575 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.70 CSW01_12720 ornithine carbamoyltransferase low > 62
Pseudomonas fluorescens GW456-L13 0.59 PfGW456L13_3767 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.61 PfGW456L13_1873 Ornithine carbamoyltransferase (EC 2.1.3.3) low > 87
Pseudomonas fluorescens SBW25-INTG 0.59 PFLU_RS17405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.59 PFLU_RS23975 ornithine carbamoyltransferase low > 109
Pseudomonas fluorescens SBW25 0.59 PFLU_RS17405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.59 PFLU_RS23975 ornithine carbamoyltransferase low > 109
Castellaniella sp019104865 MT123 0.59 ABCV34_RS04445 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.31 ABCV34_RS05380 ornithine carbamoyltransferase low > 48
Pseudomonas sp. S08-1 0.59 OH686_20470 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.60 OH686_14335 ornithine carbamoyltransferase low > 80
Paraburkholderia sabiae LMG 24235 0.57 QEN71_RS19725 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.57 QEN71_RS33040 ornithine carbamoyltransferase low > 153
Azospirillum brasilense Sp245 0.56 AZOBR_RS24275 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 0.59 AZOBR_RS13250 ornithine carbamoyltransferase low > 97
Ralstonia sp. UNC404CL21Col 0.56 ABZR87_RS20880 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.29 ABZR87_RS00840 ornithine carbamoyltransferase — —
Ralstonia solanacearum PSI07 0.55 RPSI07_RS02545 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.29 RPSI07_RS12115 ornithine carbamoyltransferase — —
Acidovorax sp. GW101-3H11 0.55 Ac3H11_2345 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.28 Ac3H11_1333 Ornithine carbamoyltransferase (EC 2.1.3.3) — —
Ralstonia solanacearum GMI1000 0.55 RS_RS20360 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.29 RS_RS12805 ornithine carbamoyltransferase — —
Ralstonia solanacearum IBSBF1503 0.55 RALBFv3_RS20320 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.28 RALBFv3_RS05185 ornithine carbamoyltransferase — —
Ralstonia solanacearum UW163 0.55 UW163_RS18855 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.28 UW163_RS08440 ornithine carbamoyltransferase — —
Shewanella sp. ANA-3 0.55 Shewana3_3469 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.29 Shewana3_3903 ornithine carbamoyltransferase (RefSeq) low > 73
Variovorax sp. SCN45 0.55 GFF795 5-methyltetrahydropteroyltriglutamate--homocystei ne methyltransferase (EC 2.1.1.14) 0.29 GFF3926 Ornithine carbamoyltransferase (EC 2.1.3.3) — —
Shewanella loihica PV-4 0.55 Shew_2986 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (RefSeq) 0.28 Shew_0204 ornithine carbamoyltransferase (RefSeq) 0.37 51
Shewanella oneidensis MR-1 0.55 SO0818 metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (NCBI ptt file) 0.30 SO0277 argF ornithine carbamoyltransferase (NCBI ptt file) 0.92 38
Marinobacter adhaerens HP15 0.54 HP15_457 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 0.65 HP15_3987 ornithine carbamoyltransferase low > 73
Mucilaginibacter yixingensis YX-36 DSM 26809 0.53 ABZR88_RS18615 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.12 ABZR88_RS15495 acetylornithine carbamoyltransferase — —
Pedobacter sp. GW460-11-11-14-LB5 0.53 CA265_RS21095 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.10 CA265_RS18520 acetylornithine carbamoyltransferase low > 88
Cupriavidus basilensis FW507-4G11 0.53 RR42_RS30660 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.28 RR42_RS17175 ornithine carbamoyltransferase — —
Shewanella amazonensis SB2B 0.53 Sama_2627 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.28 Sama_0258 ornithine carbamoyltransferase (RefSeq) 0.96 34
Variovorax sp. OAS795 0.52 ABID97_RS19395 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.29 ABID97_RS08630 ornithine carbamoyltransferase — —
Burkholderia phytofirmans PsJN 0.52 BPHYT_RS26655 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.58 BPHYT_RS27685 ornithine carbamoyltransferase 0.37 38
Rhodopseudomonas palustris CGA009 0.52 TX73_012380 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.29 TX73_024805 ornithine carbamoyltransferase — —
Caulobacter crescentus NA1000 Δfur 0.52 CCNA_00515 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.28 CCNA_02325 ornithine carbamoyltransferase low > 67
Caulobacter crescentus NA1000 0.52 CCNA_00515 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.28 CCNA_02325 ornithine carbamoyltransferase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.51 Echvi_2559 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 0.12 Echvi_3849 N-succinylornithine carbamoyltransferase (EC 2.1.3.11) (from data) low > 79
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS03225 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.20 ABZR86_RS08730 N-acetylornithine carbamoyltransferase low > 74
Desulfovibrio vulgaris Miyazaki F 0.50 DvMF_2035 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.32 DvMF_0046 ornithine carbamoyltransferase (RefSeq) low > 51
Desulfovibrio vulgaris Hildenborough JW710 0.49 DVU3371 metE 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase (TIGR) 0.30 DVU1096 argF ornithine carbamoyltransferase (TIGR) low > 55
Rhodanobacter denitrificans MT42 0.49 LRK55_RS11870 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.19 LRK55_RS02170 N-acetylornithine carbamoyltransferase low > 63
Rhodanobacter denitrificans FW104-10B01 0.49 LRK54_RS12135 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.19 LRK54_RS02415 N-acetylornithine carbamoyltransferase low > 59
Rhodospirillum rubrum S1H 0.48 Rru_A1718 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (NCBI) 0.31 Rru_A3276 Ornithine carbamoyltransferase (NCBI) low > 58
Mycobacterium tuberculosis H37Rv 0.45 Rv1133c Probable 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase MetE (methionine synthase, vitamin-B12 independent isozyme) 0.30 Rv1656 Probable ornithine carbamoyltransferase, anabolic ArgF — —
Bifidobacterium breve UCC2003 0.42 BBR_RS15405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.33 BBR_RS13905 ornithine carbamoyltransferase low > 34

Not shown: 0 genomes with orthologs for ECD_03708 only; 33 genomes with orthologs for ECD_04120 only