Conservation of cofitness between ECD_04103 and ECD_03349 in Escherichia coli BL21

76 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_04103 putative antibiotic peptide MccB17 maturation peptidase 1.0 ECD_03349 glutathione oxidoreductase low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03800 Metalloprotease PmbA 1.00 OHPLBJKB_00203 Glutathione reductase low > 73
Escherichia coli ECRC102 1.00 NIAGMN_09775 pmbA metalloprotease PmbA 1.00 NIAGMN_14170 gorA glutathione-disulfide reductase
Escherichia coli ECRC100 1.00 OKFHMN_11925 pmbA metalloprotease PmbA 1.00 OKFHMN_16405 gorA glutathione-disulfide reductase 0.84 34
Escherichia coli ECRC101 1.00 MCAODC_02430 pmbA metalloprotease PmbA 1.00 MCAODC_06920 gorA glutathione-disulfide reductase low > 87
Escherichia coli ECRC62 1.00 BNILDI_07325 pmbA metalloprotease PmbA 1.00 BNILDI_03220 gorA glutathione-disulfide reductase low > 75
Escherichia coli ECOR27 1.00 NOLOHH_04185 pmbA metalloprotease PmbA 1.00 NOLOHH_08340 gorA glutathione-disulfide reductase 0.69 9
Escherichia coli ECRC98 1.00 JDDGAC_15565 pmbA metalloprotease PmbA 1.00 JDDGAC_20035 gorA glutathione-disulfide reductase low > 86
Escherichia coli ECOR38 1.00 HEPCGN_10125 pmbA metalloprotease PmbA 1.00 HEPCGN_15315 gorA glutathione-disulfide reductase low > 87
Escherichia coli ECRC99 1.00 KEDOAH_16230 pmbA metalloprotease PmbA 1.00 KEDOAH_11740 gorA glutathione-disulfide reductase
Escherichia coli BW25113 1.00 b4235 pmbA predicted peptidase required for the maturation and secretion of the antibiotic peptide MccB17 (NCBI) 1.00 b3500 gor glutathione reductase (NCBI) low > 76
Escherichia fergusonii Becca 0.99 EFB2_04298 Metalloprotease PmbA 1.00 EFB2_00315 Glutathione reductase low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS24570 metalloprotease PmbA 1.00 ECOLIN_RS19995 glutathione-disulfide reductase 0.41 38
Enterobacter sp. TBS_079 0.96 MPMX20_00517 Metalloprotease PmbA 0.91 MPMX20_04399 Glutathione reductase low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF904 TldE protein, part of TldE/TldD proteolytic complex 0.93 GFF513 Glutathione reductase (EC 1.8.1.7) low > 78
Enterobacter asburiae PDN3 0.96 EX28DRAFT_3422 Predicted Zn-dependent proteases and their inactivated homologs 0.91 EX28DRAFT_4061 NADPH-glutathione reductase (EC 1.8.1.7) low > 76
Klebsiella michiganensis M5al 0.94 BWI76_RS02850 metalloprotease PmbA 0.91 BWI76_RS26685 glutathione-disulfide reductase low > 92
Serratia liquefaciens MT49 0.86 IAI46_22575 metalloprotease PmbA 0.86 IAI46_24240 glutathione-disulfide reductase low > 86
Rahnella sp. WP5 0.85 EX31_RS12320 metalloprotease PmbA 0.85 EX31_RS05175 glutathione-disulfide reductase low > 89
Pectobacterium carotovorum WPP14 0.84 HER17_RS20090 metalloprotease PmbA 0.87 HER17_RS21240 glutathione-disulfide reductase low > 75
Pantoea sp. MT58 0.84 IAI47_02765 metalloprotease PmbA 0.87 IAI47_01325 glutathione-disulfide reductase low > 76
Dickeya dadantii 3937 0.81 DDA3937_RS01500 metalloprotease PmbA 0.86 DDA3937_RS21245 glutathione-disulfide reductase low > 74
Erwinia tracheiphila SCR3 0.81 LU632_RS02145 pmbA metalloprotease PmbA 0.85 LU632_RS19495 gorA glutathione-disulfide reductase low > 74
Dickeya dianthicola 67-19 0.81 HGI48_RS01415 metalloprotease PmbA 0.85 HGI48_RS00065 glutathione-disulfide reductase low > 71
Dickeya dianthicola ME23 0.81 DZA65_RS01480 metalloprotease PmbA 0.86 DZA65_RS00055 glutathione-disulfide reductase low > 75
Vibrio cholerae E7946 ATCC 55056 0.64 CSW01_12845 metalloprotease PmbA 0.73 CSW01_01000 glutathione-disulfide reductase low > 62
Shewanella amazonensis SB2B 0.59 Sama_0482 PmbA protein (RefSeq) 0.71 Sama_3543 glutathione reductase (RefSeq) low > 62
Shewanella sp. ANA-3 0.59 Shewana3_3631 microcin-processing peptidase 1 (RefSeq) 0.71 Shewana3_4054 glutathione reductase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.59 SO4078 pmbA pmba protein (NCBI ptt file) 0.70 SO4702 gor glutathione reductase (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.57 Shew_0416 peptidase U62, modulator of DNA gyrase (RefSeq) 0.70 Shew_3660 glutathione reductase (RefSeq) low > 60
Alteromonas macleodii MIT1002 0.54 MIT1002_00230 peptidase PmbA 0.65 MIT1002_03638 Glutathione reductase low > 70
Pseudomonas sp. RS175 0.48 PFR28_00163 Metalloprotease PmbA 0.40 PFR28_02483 Glutathione reductase 0.28 33
Pseudomonas fluorescens FW300-N2C3 0.48 AO356_07085 peptidase PmbA 0.40 AO356_22800 glutathione reductase 0.38 14
Pseudomonas fluorescens SBW25 0.48 PFLU_RS04350 metalloprotease PmbA 0.40 PFLU_RS14555 glutathione-disulfide reductase low > 109
Pseudomonas fluorescens SBW25-INTG 0.48 PFLU_RS04350 metalloprotease PmbA 0.40 PFLU_RS14555 glutathione-disulfide reductase low > 109
Pseudomonas fluorescens FW300-N2E2 0.48 Pf6N2E2_3278 TldE protein, part of TldE/TldD proteolytic complex 0.40 Pf6N2E2_446 Glutathione reductase (EC 1.8.1.7) low > 103
Pseudomonas simiae WCS417 0.47 PS417_04295 peptidase PmbA 0.40 PS417_14060 glutathione reductase
Pseudomonas putida KT2440 0.47 PP_0942 regulatory protease 0.41 PP_3819 glutathione reductase (NADPH) low > 96
Pseudomonas fluorescens FW300-N1B4 0.47 Pf1N1B4_1090 TldE protein, part of TldE/TldD proteolytic complex 0.40 Pf1N1B4_5014 Glutathione reductase (EC 1.8.1.7) low > 87
Pseudomonas fluorescens GW456-L13 0.47 PfGW456L13_5024 TldE protein, part of TldE/TldD proteolytic complex 0.40 PfGW456L13_2924 Glutathione reductase (EC 1.8.1.7) low > 87
Pseudomonas fluorescens FW300-N2E3 0.47 AO353_05205 peptidase PmbA 0.40 AO353_24480 glutathione reductase low > 101
Pseudomonas syringae pv. syringae B728a 0.46 Psyr_4154 microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 0.37 Psyr_2979 NADPH-glutathione reductase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.46 Psyr_4154 microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 0.37 Psyr_2979 NADPH-glutathione reductase low > 86
Herbaspirillum seropedicae SmR1 0.45 HSERO_RS09265 peptidase C69 0.37 HSERO_RS16580 glutathione reductase low > 78
Pseudomonas stutzeri RCH2 0.45 Psest_3318 Predicted Zn-dependent proteases and their inactivated homologs 0.39 Psest_2230 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes low > 67
Xanthomonas campestris pv. campestris strain 8004 0.45 Xcc-8004.1885.1 TldE protein, part of TldE/TldD proteolytic complex 0.41 Xcc-8004.1917.1 Glutathione reductase (EC 1.8.1.7) low > 74
Variovorax sp. OAS795 0.45 ABID97_RS20695 metalloprotease PmbA 0.36 ABID97_RS00865 glutathione-disulfide reductase low > 91
Dyella japonica UNC79MFTsu3.2 0.45 ABZR86_RS21700 metalloprotease PmbA 0.45 ABZR86_RS08925 glutathione-disulfide reductase low > 74
Rhodanobacter sp. FW510-T8 0.45 OKGIIK_10260 pmbA metalloprotease PmbA 0.21 OKGIIK_14635 lpd NAD(P)/FAD-dependent oxidoreductase low > 52
Pseudomonas sp. S08-1 0.45 OH686_08570 TldE protein, part of TldE/TldD proteolytic complex 0.40 OH686_01610 glutathione-disulfide reductase low > 80
Variovorax sp. SCN45 0.45 GFF4697 TldE protein, part of TldE/TldD proteolytic complex 0.38 GFF3591 Glutathione reductase (EC 1.8.1.7) low > 127
Rhodanobacter denitrificans MT42 0.44 LRK55_RS03125 metalloprotease PmbA 0.22 LRK55_RS17305 NAD(P)/FAD-dependent oxidoreductase low > 63
Rhodanobacter denitrificans FW104-10B01 0.44 LRK54_RS03375 metalloprotease PmbA 0.21 LRK54_RS09620 NAD(P)/FAD-dependent oxidoreductase low > 59
Ralstonia solanacearum IBSBF1503 0.43 RALBFv3_RS13965 metalloprotease PmbA 0.22 RALBFv3_RS09465 NAD(P)/FAD-dependent oxidoreductase low > 76
Ralstonia solanacearum UW163 0.43 UW163_RS15845 metalloprotease PmbA 0.22 UW163_RS04115 NAD(P)/FAD-dependent oxidoreductase
Ralstonia sp. UNC404CL21Col 0.43 ABZR87_RS09660 metalloprotease PmbA 0.23 ABZR87_RS05295 NAD(P)/FAD-dependent oxidoreductase low > 80
Ralstonia solanacearum PSI07 0.43 RPSI07_RS19505 metalloprotease PmbA 0.24 RPSI07_RS23885 NAD(P)/FAD-dependent oxidoreductase low > 81
Kangiella aquimarina DSM 16071 0.43 B158DRAFT_2075 microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 0.61 B158DRAFT_0460 NADPH-glutathione reductase (EC 1.8.1.7) low > 40
Hydrogenophaga sp. GW460-11-11-14-LB1 0.41 GFF3655 TldE protein, part of TldE/TldD proteolytic complex 0.36 GFF372 Glutathione reductase (EC 1.8.1.7) low > 90
Lysobacter sp. OAE881 0.41 ABIE51_RS06805 metalloprotease PmbA 0.40 ABIE51_RS06410 glutathione-disulfide reductase low > 62
Ralstonia solanacearum GMI1000 0.41 RS_RS04700 metalloprotease PmbA 0.23 RS_RS00065 NAD(P)/FAD-dependent oxidoreductase low > 80
Cupriavidus basilensis FW507-4G11 0.41 RR42_RS14750 peptidase PMbA 0.26 RR42_RS20585 pyridine nucleotide-disulfide oxidoreductase low > 128
Azospirillum brasilense Sp245 0.34 AZOBR_RS11930 modulator protein 0.39 AZOBR_RS09745 glutathione reductase low > 97
Azospirillum sp. SherDot2 0.34 MPMX19_01886 Metalloprotease PmbA 0.40 MPMX19_04368 Glutathione amide reductase low > 112
Sphingomonas koreensis DSMZ 15582 0.30 Ga0059261_0810 Predicted Zn-dependent proteases and their inactivated homologs 0.35 Ga0059261_1951 NADPH-glutathione reductase (EC 1.8.1.7) low > 68
Magnetospirillum magneticum AMB-1 0.29 AMB_RS22120 TldD/PmbA family protein 0.38 AMB_RS08430 glutathione-disulfide reductase low > 64
Rhodopseudomonas palustris CGA009 0.29 TX73_005930 TldD/PmbA family protein 0.33 TX73_010220 glutathione-disulfide reductase
Rhodospirillum rubrum S1H 0.29 Rru_A0575 Peptidase U62, modulator of DNA gyrase (NCBI) 0.37 Rru_A0682 Glutathione reductase (NCBI)
Caulobacter crescentus NA1000 0.28 CCNA_00311 Zn-dependent protease family protein 0.35 CCNA_02387 glutathione reductase low > 66
Caulobacter crescentus NA1000 Δfur 0.28 CCNA_00311 Zn-dependent protease family protein 0.35 CCNA_02387 glutathione reductase low > 67
Sinorhizobium meliloti 1021 0.28 SMc00897 PMBA protein 0.31 SMc00154 glutathione reductase
Brevundimonas sp. GW460-12-10-14-LB2 0.28 A4249_RS09195 TldD/PmbA family protein 0.33 A4249_RS06570 glutathione-disulfide reductase low > 48
Agrobacterium fabrum C58 0.27 Atu0693 PmbA/TldD related protein 0.31 Atu1611 glutathione reductase
Phaeobacter inhibens DSM 17395 0.27 PGA1_c33480 protein PmbA 0.33 PGA1_c23720 glutathione reductase Gor
Rhizobium sp. OAE497 0.27 ABIE40_RS03780 TldD/PmbA family protein 0.32 ABIE40_RS10515 glutathione-disulfide reductase low > 107
Dinoroseobacter shibae DFL-12 0.26 Dshi_0064 peptidase U62 modulator of DNA gyrase (RefSeq) 0.31 Dshi_2737 pyridine nucleotide-disulphide oxidoreductase dimerisation region (RefSeq) low > 64
Synechococcus elongatus PCC 7942 0.09 Synpcc7942_1289 pmbA putative modulator of DNA gyrase 0.37 Synpcc7942_0842 gor glutathione reductase low > 38

Not shown: 12 genomes with orthologs for ECD_04103 only; 4 genomes with orthologs for ECD_03349 only