| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_07180 | | tRNA 2-thiocytidine(32) synthetase TtcA | 1.0 | CSW01_12885 | | fructose 1,6-bisphosphatase | 0.61 | 9 |
| Escherichia coli ECRC62 | 0.77 | BNILDI_18020 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.76 | BNILDI_07310 | fbp | class 1 fructose-bisphosphatase | low | > 75 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.77 | OHPLBJKB_02337 | | tRNA-cytidine(32) 2-sulfurtransferase | 0.76 | OHPLBJKB_03803 | | Fructose-1,6-bisphosphatase class 1 | low | > 74 |
| Escherichia coli ECRC101 | 0.77 | MCAODC_16100 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.76 | MCAODC_02450 | fbp | class 1 fructose-bisphosphatase | low | > 87 |
| Escherichia coli ECRC99 | 0.77 | KEDOAH_26600 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.76 | KEDOAH_16210 | fbp | class 1 fructose-bisphosphatase | — | — |
| Escherichia coli Nissle 1917 | 0.77 | ECOLIN_RS08065 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.76 | ECOLIN_RS24555 | | class 1 fructose-bisphosphatase | — | — |
| Klebsiella michiganensis M5al | 0.77 | BWI76_RS12710 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.76 | BWI76_RS02815 | | fructose-bisphosphatase class I | low | > 92 |
| Escherichia coli BL21 | 0.77 | ECD_01321 | | tRNA s(2)C32 thioltransferase, iron sulfur cluster protein | 0.76 | ECD_04100 | | fructose-1,6-bisphosphatase I | low | > 61 |
| Escherichia coli ECRC102 | 0.77 | NIAGMN_26325 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.76 | NIAGMN_09795 | fbp | class 1 fructose-bisphosphatase | low | > 80 |
| Enterobacter sp. TBS_079 | 0.77 | MPMX20_02440 | | tRNA-cytidine(32) 2-sulfurtransferase | 0.76 | MPMX20_00514 | | Fructose-1,6-bisphosphatase class 1 | low | > 85 |
| Escherichia coli ECOR27 | 0.77 | NOLOHH_19870 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.76 | NOLOHH_04205 | fbp | class 1 fructose-bisphosphatase | low | > 75 |
| Escherichia coli BW25113 | 0.77 | b1344 | ydaO | predicted C32 tRNA thiolase (NCBI) | 0.76 | b4232 | fbp | fructose-1,6-bisphosphatase (NCBI) | low | > 76 |
| Enterobacter asburiae PDN3 | 0.76 | EX28DRAFT_1007 | | Predicted ATPase of the PP-loop superfamily implicated in cell cycle control | 0.76 | EX28DRAFT_3419 | | Fructose-1,6-bisphosphatase | low | > 76 |
| Escherichia coli ECRC100 | 0.76 | OKFHMN_02155 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.76 | OKFHMN_11945 | fbp | class 1 fructose-bisphosphatase | — | — |
| Pectobacterium carotovorum WPP14 | 0.76 | HER17_RS09605 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.76 | HER17_RS02620 | | class 1 fructose-bisphosphatase | low | > 75 |
| Escherichia fergusonii Becca | 0.76 | EFB2_02583 | | tRNA-cytidine(32) 2-sulfurtransferase | 0.76 | EFB2_04301 | | Fructose-1,6-bisphosphatase class 1 | low | > 86 |
| Escherichia coli ECOR38 | 0.76 | HEPCGN_26005 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.76 | HEPCGN_10145 | fbp | class 1 fructose-bisphosphatase | low | > 88 |
| Klebsiella pneumoniae MRSN742743 | 0.76 | GJGHJB_02752 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.76 | GJGHJB_04517 | fbp | class 1 fructose-bisphosphatase | low | > 83 |
| Klebsiella pneumoniae MKP103 | 0.76 | KDGMDA_20605 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.76 | KDGMDA_11305 | | class 1 fructose-bisphosphatase | low | > 94 |
| Dickeya dadantii 3937 | 0.76 | DDA3937_RS12330 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.75 | DDA3937_RS18575 | | class 1 fructose-bisphosphatase | low | > 74 |
| Escherichia coli ECRC98 | 0.76 | JDDGAC_04715 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.76 | JDDGAC_15585 | fbp | class 1 fructose-bisphosphatase | low | > 87 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.76 | GFF2648 | | tRNA(Cytosine32)-2-thiocytidine synthetase | 0.76 | GFF880 | | Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) | low | > 78 |
| Dickeya dianthicola ME23 | 0.76 | DZA65_RS12850 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.76 | DZA65_RS19645 | | class 1 fructose-bisphosphatase | low | > 75 |
| Dickeya dianthicola 67-19 | 0.76 | HGI48_RS12410 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.76 | HGI48_RS18510 | | class 1 fructose-bisphosphatase | low | > 71 |
| Pantoea agglomerans CFBP13505 P0401 | 0.75 | PagCFBP13516_RS09630 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.74 | PagCFBP13516_RS02765 | fbp | class 1 fructose-bisphosphatase | low | > 80 |
| Serratia liquefaciens MT49 | 0.75 | IAI46_13420 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.76 | IAI46_01795 | | class 1 fructose-bisphosphatase | low | > 87 |
| Pantoea sp. MT58 | 0.75 | IAI47_09475 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.74 | IAI47_02750 | | class 1 fructose-bisphosphatase | low | > 76 |
| Erwinia amylovora T8 | 0.74 | OLJFJH_13765 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.75 | OLJFJH_02370 | | class 1 fructose-bisphosphatase | — | — |
| Rahnella sp. WP5 | 0.73 | EX31_RS06375 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.75 | EX31_RS08670 | | class 1 fructose-bisphosphatase | low | > 89 |
| Alteromonas macleodii MIT1002 | 0.72 | MIT1002_02139 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.35 | MIT1002_00169 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Pseudomonas stutzeri RCH2 | 0.64 | Psest_3033 | | Predicted ATPase of the PP-loop superfamily implicated in cell cycle control | 0.39 | Psest_3956 | | Fructose-1,6-bisphosphatase | — | — |
| Pseudomonas sp. S08-1 | 0.64 | OH686_05145 | | tRNA-(cytosine32)-2-thiocytidine synthetase TtcA | 0.39 | OH686_10290 | | Fructose-1,6-bisphosphatase, type I | — | — |
| Shewanella amazonensis SB2B | 0.64 | Sama_1801 | | hypothetical protein (RefSeq) | 0.37 | Sama_0599 | | fructose-1,6-bisphosphatase (RefSeq) | — | — |
| Shewanella sp. ANA-3 | 0.64 | Shewana3_2117 | | PP-loop domain-containing protein (RefSeq) | 0.35 | Shewana3_0648 | | fructose-1,6-bisphosphatase (RefSeq) | low | > 73 |
| Pseudomonas aeruginosa MRSN321 | 0.64 | PFGADD_03934 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.39 | PFGADD_05349 | fbp | class 1 fructose-bisphosphatase | — | — |
| Pseudomonas aeruginosa PA14 | 0.64 | IKLFDK_05600 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.40 | IKLFDK_27970 | | class 1 fructose-bisphosphatase | — | — |
| Pseudomonas aeruginosa PUPa3 | 0.64 | NPBIFN_03985 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.39 | NPBIFN_05426 | fbp | class 1 fructose-bisphosphatase | — | — |
| Pseudomonas segetis P6 | 0.63 | ACVTMO_RS08965 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.40 | ACVTMO_RS21205 | | class 1 fructose-bisphosphatase | — | — |
| Shewanella oneidensis MR-1 | 0.63 | SO2354 | | conserved hypothetical protein (NCBI ptt file) | 0.35 | SO3991 | fbp | fructose-1,6-bisphosphatase (NCBI ptt file) | — | — |
| Pseudomonas sp. DMC3 | 0.63 | GFF4833 | | tRNA-cytidine(32) 2-sulfurtransferase | 0.38 | GFF4070 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Pseudomonas sp. RS175 | 0.63 | PFR28_03236 | | tRNA-cytidine(32) 2-sulfurtransferase | 0.38 | PFR28_04956 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Pseudomonas simiae WCS417 | 0.63 | PS417_16415 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.38 | PS417_01690 | | fructose 1,6-bisphosphatase | — | — |
| Pseudomonas lactucae CFBP13502 | 0.63 | GEMAOFIL_03610 | | tRNA-cytidine(32) 2-sulfurtransferase | 0.38 | GEMAOFIL_00560 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Pseudomonas putida KT2440 | 0.63 | PP_1641 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.39 | PP_5040 | | fructose-1,6-bisphosphatase, class 1 | — | — |
| Pseudomonas sp. BP01 | 0.63 | JOY50_RS23840 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.38 | JOY50_RS09485 | | class 1 fructose-bisphosphatase | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.63 | QEN71_RS28595 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.41 | QEN71_RS03770 | | class 1 fructose-bisphosphatase | — | — |
| Pseudomonas protegens RBAN4 | 0.63 | FABNJH_23060 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.38 | FABNJH_02060 | fbp | class 1 fructose-bisphosphatase | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.63 | Pf6N2E2_5711 | | tRNA(Cytosine32)-2-thiocytidine synthetase | 0.38 | Pf6N2E2_3813 | | Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.63 | PfGW456L13_2020 | | tRNA(Cytosine32)-2-thiocytidine synthetase | 0.39 | PfGW456L13_335 | | Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.63 | AO353_02780 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.38 | AO353_12205 | | fructose 1,6-bisphosphatase | — | — |
| Pseudomonas sp. FW215-L2 | 0.62 | GFF2790 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.37 | GFF558 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.62 | Pf1N1B4_3491 | | tRNA(Cytosine32)-2-thiocytidine synthetase | 0.39 | Pf1N1B4_1596 | | Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.62 | AO356_19000 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.38 | AO356_09670 | | fructose 1,6-bisphosphatase | — | — |
| Acidovorax sp. GW101-3H11 | 0.62 | Ac3H11_1817 | | tRNA(Cytosine32)-2-thiocytidine synthetase | 0.41 | Ac3H11_2634 | | Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.62 | H281DRAFT_05824 | | tRNA s(2)C-32 sulfurtransferase | 0.42 | H281DRAFT_03991 | | D-fructose 1,6-bisphosphatase | — | — |
| Pseudomonas sp. SVBP6 | 0.62 | COO64_RS07395 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.39 | COO64_RS13370 | | class 1 fructose-bisphosphatase | — | — |
| Pseudomonas orientalis W4I3 | 0.62 | QF045_RS18170 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.38 | QF045_RS04755 | | class 1 fructose-bisphosphatase | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.62 | Psyr_3705 | | conserved hypothetical protein | 0.38 | Psyr_0370 | | D-fructose 1,6-bisphosphatase | — | — |
| Burkholderia phytofirmans PsJN | 0.62 | BPHYT_RS18570 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.42 | BPHYT_RS15225 | | fructose-1,6-bisphosphatase class 1 | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.62 | Psyr_3705 | | conserved hypothetical protein | 0.38 | Psyr_0370 | | D-fructose 1,6-bisphosphatase | — | — |
| Pseudomonas fluorescens SBW25 | 0.62 | PFLU_RS18455 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.37 | PFLU_RS01745 | | class 1 fructose-bisphosphatase | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.62 | PFLU_RS18455 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.37 | PFLU_RS01745 | | class 1 fructose-bisphosphatase | — | — |
| Paraburkholderia graminis OAS925 | 0.62 | ABIE53_000036 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.42 | ABIE53_003219 | | fructose-1,6-bisphosphatase I | — | — |
| Ralstonia sp. UNC404CL21Col | 0.61 | ABZR87_RS05700 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.41 | ABZR87_RS15125 | | class 1 fructose-bisphosphatase | — | — |
| Ralstonia solanacearum PSI07 | 0.61 | RPSI07_RS23130 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.40 | RPSI07_RS14035 | | class 1 fructose-bisphosphatase | — | — |
| Shewanella loihica PV-4 | 0.61 | Shew_1995 | | PP-loop domain-containing protein (RefSeq) | 0.35 | Shew_0773 | | fructose-1,6-bisphosphatase (RefSeq) | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.61 | RALBFv3_RS10245 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.40 | RALBFv3_RS03275 | | class 1 fructose-bisphosphatase | — | — |
| Ralstonia solanacearum UW163 | 0.61 | UW163_RS03335 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.40 | UW163_RS10450 | | class 1 fructose-bisphosphatase | — | — |
| Herbaspirillum seropedicae SmR1 | 0.61 | HSERO_RS22035 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.41 | HSERO_RS17715 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Ralstonia solanacearum GMI1000 | 0.61 | RS_RS00865 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.41 | RS_RS10665 | | fructose 1,6-bisphosphatase | — | — |
| Erwinia tracheiphila SCR3 | 0.60 | LU632_RS12165 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.75 | LU632_RS02130 | fbp | class 1 fructose-bisphosphatase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.60 | RR42_RS01445 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.40 | RR42_RS05195 | | fructose 1,6-bisphosphatase | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.60 | ABZR86_RS16485 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.36 | ABZR86_RS15255 | | class 1 fructose-bisphosphatase | low | > 74 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.60 | GFF1658 | | tRNA(Cytosine32)-2-thiocytidine synthetase | 0.40 | GFF274 | | Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) | — | — |
| Dechlorosoma suillum PS | 0.60 | Dsui_0695 | | putative ATPase of the PP-loop superfamily implicated in cell cycle control | 0.41 | Dsui_1563 | | fructose-1,6-bisphosphatase | — | — |
| Collimonas humicola GW821-FHT01A05 | 0.59 | MPMX01_00462 | | tRNA-cytidine(32) 2-sulfurtransferase | 0.39 | MPMX01_01105 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Variovorax sp. SCN45 | 0.59 | GFF7310 | | tRNA-(cytosine32)-2-thiocytidine synthetase TtcA | 0.39 | GFF3119 | | Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) | — | — |
| Variovorax sp. OAS795 | 0.59 | ABID97_RS06505 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.43 | ABID97_RS12875 | | class 1 fructose-bisphosphatase | low | > 91 |
| Castellaniella sp019104865 MT123 | 0.59 | ABCV34_RS10450 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.40 | ABCV34_RS02565 | | class 1 fructose-bisphosphatase | — | — |
| Methylophilus sp. DMC18 | 0.58 | GFF1541 | | tRNA-cytidine(32) 2-sulfurtransferase | 0.31 | GFF2746 | | Fructose-1,6-bisphosphatase class 1 | low | > 43 |
| Lysobacter sp. OAE881 | 0.58 | ABIE51_RS01305 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.36 | ABIE51_RS00860 | | class 1 fructose-bisphosphatase | 0.29 | 22 |
| Acinetobacter baumannii LAC-4 | 0.55 | RR41_RS04315 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.39 | RR41_RS04640 | | class 1 fructose-bisphosphatase | — | — |
| Rhodanobacter denitrificans MT42 | 0.55 | LRK55_RS10320 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.36 | LRK55_RS08130 | | class 1 fructose-bisphosphatase | low | > 63 |
| Rhodanobacter denitrificans FW104-10B01 | 0.54 | LRK54_RS10680 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.36 | LRK54_RS08365 | | class 1 fructose-bisphosphatase | low | > 59 |
| Acinetobacter radioresistens SK82 | 0.54 | MPMX26_00810 | | tRNA-cytidine(32) 2-sulfurtransferase | 0.37 | MPMX26_02197 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.51 | Xcc-8004.5211.1 | | tRNA(Cytosine32)-2-thiocytidine synthetase | 0.38 | Xcc-8004.127.1 | | Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) | low | > 74 |
| Sinorhizobium meliloti 1021 | 0.46 | SMc00534 | | C32 tRNA thiolase | 0.31 | SM_b20202 | | fructose-1,6-bisphosphatase | low | > 103 |
Not shown: 6 genomes with orthologs for CSW01_07180 only; 20 genomes with orthologs for CSW01_12885 only