Conservation of cofitness between CSW01_01845 and CSW01_07190 in Vibrio cholerae E7946 ATCC 55056

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_01845 protease modulator HflK 1.0 CSW01_07190 transcriptional regulator FNR 0.76 2
Shewanella sp. ANA-3 0.51 Shewana3_0599 HflK protein (RefSeq) 0.77 Shewana3_2115 fumarate/nitrate reduction transcriptional regulator (RefSeq)
Shewanella oneidensis MR-1 0.50 SO0605 hflK hflK protein (NCBI ptt file) 0.76 SO2356 etrA electron transport regulator a (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.50 Shew_0568 HflK protein (RefSeq) 0.76 Shew_1993 fumarate/nitrate reduction transcriptional regulator (RefSeq)
Escherichia fergusonii Becca 0.49 EFB2_04361 Modulator of FtsH protease HflK 0.85 EFB2_02593 Fumarate and nitrate reduction regulatory protein low > 86
Escherichia coli Nissle 1917 0.49 ECOLIN_RS24240 FtsH protease activity modulator HflK 0.85 ECOLIN_RS08005 fumarate/nitrate reduction transcriptional regulator Fnr low > 55
Escherichia coli ECOR38 0.49 HEPCGN_10475 hflK FtsH protease activity modulator HflK 0.85 HEPCGN_25925 fnr fumarate/nitrate reduction transcriptional regulator Fnr low > 88
Escherichia coli ECRC102 0.48 NIAGMN_10095 hflK FtsH protease activity modulator HflK 0.85 NIAGMN_26410 fnr fumarate/nitrate reduction transcriptional regulator Fnr
Escherichia coli HS(pFamp)R (ATCC 700891) 0.48 OHPLBJKB_03868 Modulator of FtsH protease HflK 0.85 OHPLBJKB_02348 Fumarate and nitrate reduction regulatory protein low > 74
Escherichia coli ECRC101 0.48 MCAODC_02760 hflK FtsH protease activity modulator HflK 0.85 MCAODC_16030 fnr fumarate/nitrate reduction transcriptional regulator Fnr low > 88
Escherichia coli ECRC100 0.48 OKFHMN_12245 hflK FtsH protease activity modulator HflK 0.85 OKFHMN_02240 fnr fumarate/nitrate reduction transcriptional regulator Fnr low > 79
Escherichia coli ECOR27 0.48 NOLOHH_04510 hflK FtsH protease activity modulator HflK 0.85 NOLOHH_19940 fnr fumarate/nitrate reduction transcriptional regulator Fnr low > 76
Escherichia coli ECRC98 0.48 JDDGAC_15885 hflK FtsH protease activity modulator HflK 0.85 JDDGAC_04785 fnr fumarate/nitrate reduction transcriptional regulator Fnr low > 87
Escherichia coli ECRC62 0.48 BNILDI_06980 hflK FtsH protease activity modulator HflK 0.85 BNILDI_18090 fnr fumarate/nitrate reduction transcriptional regulator Fnr low > 75
Escherichia coli BW25113 0.48 b4174 hflK modulator for HflB protease specific for phage lambda cII repressor (NCBI) 0.85 b1334 fnr DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) low > 76
Klebsiella pneumoniae MKP103 0.48 KDGMDA_11045 FtsH protease activity modulator HflK 0.85 KDGMDA_21005 fumarate/nitrate reduction transcriptional regulator Fnr low > 95
Escherichia coli ECRC99 0.48 KEDOAH_15910 hflK FtsH protease activity modulator HflK 0.85 KEDOAH_26530 fnr fumarate/nitrate reduction transcriptional regulator Fnr
Enterobacter asburiae PDN3 0.48 EX28DRAFT_3371 HflK protein 0.84 EX28DRAFT_1540 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases low > 76
Dickeya dadantii 3937 0.48 DDA3937_RS18600 FtsH protease activity modulator HflK 0.86 DDA3937_RS10950 fumarate/nitrate reduction transcriptional regulator Fnr low > 74
Dickeya dianthicola ME23 0.48 DZA65_RS19670 FtsH protease activity modulator HflK 0.86 DZA65_RS11360 fumarate/nitrate reduction transcriptional regulator Fnr low > 75
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.48 GFF827 HflK protein 0.85 GFF2656 Fumarate and nitrate reduction regulatory protein low > 78
Alteromonas macleodii MIT1002 0.48 MIT1002_03786 Modulator of FtsH protease HflK 0.57 MIT1002_02137 Fumarate and nitrate reduction regulatory protein low > 70
Dickeya dianthicola 67-19 0.48 HGI48_RS18535 FtsH protease activity modulator HflK 0.86 HGI48_RS10900 fumarate/nitrate reduction transcriptional regulator Fnr low > 71
Shewanella amazonensis SB2B 0.47 Sama_3023 hflK protein (RefSeq) 0.76 Sama_1799 fumarate/nitrate reduction transcriptional regulator (RefSeq) low > 62
Pantoea sp. MT58 0.47 IAI47_02600 FtsH protease activity modulator HflK 0.85 IAI47_09580 FNR family transcription factor low > 76
Erwinia tracheiphila HP pepo 2.2 0.46 IJEDHG_06855 hflK FtsH protease activity modulator HflK 0.83 IJEDHG_23150 crp transcriptional regulator FNR
Pectobacterium carotovorum WPP14 0.46 HER17_RS02595 FtsH protease activity modulator HflK 0.86 HER17_RS10525 fumarate/nitrate reduction transcriptional regulator Fnr low > 75
Erwinia tracheiphila SCR3 0.46 LU632_RS02065 hflK FtsH protease activity modulator HflK 0.83 LU632_RS11420 FNR family transcription factor low > 74
Pantoea agglomerans CFBP13505 P0401 0.46 PagCFBP13505_RS11195 FtsH protease activity modulator HflK 0.86 PagCFBP13505_RS06575 fumarate/nitrate reduction transcriptional regulator Fnr low > 74
Enterobacter sp. TBS_079 0.46 MPMX20_00455 Modulator of FtsH protease HflK 0.85 MPMX20_02035 Fumarate and nitrate reduction regulatory protein low > 85
Klebsiella michiganensis M5al 0.45 BWI76_RS02545 protease modulator HflK 0.85 BWI76_RS16185 transcriptional regulator FNR
Serratia liquefaciens MT49 0.45 IAI46_01635 FtsH protease activity modulator HflK 0.86 IAI46_13260 FNR family transcription factor low > 86
Rahnella sp. WP5 0.45 EX31_RS08810 FtsH protease activity modulator HflK 0.86 EX31_RS07200 FNR family transcription factor low > 89
Erwinia amylovora T8 0.44 OLJFJH_02490 FtsH protease activity modulator HflK 0.83 OLJFJH_13925 transcriptional regulator FNR low > 58
Marinobacter adhaerens HP15 0.37 HP15_2497 HflK 0.41 HP15_634 transcriptional regulator, Crp/Fnr family low > 73
Pseudomonas fluorescens FW300-N1B4 0.37 Pf1N1B4_1410 HflK protein 0.53 Pf1N1B4_3867 Fumarate and nitrate reduction regulatory protein
Pseudomonas fluorescens SBW25 0.36 PFLU_RS02580 FtsH protease activity modulator HflK 0.53 PFLU_RS22395 fumarate/nitrate reduction transcriptional regulator Fnr low > 109
Pseudomonas fluorescens SBW25-INTG 0.36 PFLU_RS02580 FtsH protease activity modulator HflK 0.53 PFLU_RS22395 fumarate/nitrate reduction transcriptional regulator Fnr low > 109
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_08645 hypothetical protein 0.53 AO356_02485 transcriptional regulator low > 104
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_13155 hypothetical protein 0.53 AO353_00660 transcriptional regulator low > 101
Pseudomonas aeruginosa PA14 0.36 IKLFDK_28830 FtsH protease activity modulator HflK 0.53 IKLFDK_07375 transcriptional regulator Anr
Pseudomonas segetis P6 0.36 MPMX49_04151 Modulator of FtsH protease HflK 0.54 MPMX49_02303 Transcriptional activator protein Anr low > 75
Pseudomonas sp. RS175 0.36 PFR28_05123 Modulator of FtsH protease HflK 0.53 PFR28_01079 Transcriptional activator protein Anr
Pseudomonas syringae pv. syringae B728a 0.35 Psyr_0574 protease FtsH subunit HflK 0.54 Psyr_3425 Cyclic nucleotide-binding:Bacterial regulatory protein, Crp low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.35 Psyr_0574 protease FtsH subunit HflK 0.54 Psyr_3425 Cyclic nucleotide-binding:Bacterial regulatory protein, Crp
Pseudomonas sp. DMC3 0.35 GFF3222 Modulator of FtsH protease HflK 0.54 GFF711 Transcriptional activator protein Anr
Dechlorosoma suillum PS 0.35 Dsui_3135 HflK protein 0.40 Dsui_1646 cAMP-binding protein
Pseudomonas fluorescens FW300-N2E2 0.35 Pf6N2E2_3612 HflK protein 0.53 Pf6N2E2_2323 Fumarate and nitrate reduction regulatory protein low > 103
Pseudomonas simiae WCS417 0.35 PS417_02500 membrane protein 0.53 PS417_20785 transcriptional regulator
Pseudomonas lactucae CFBP13502 0.35 GEMAOFIL_00738 Modulator of FtsH protease HflK 0.53 GEMAOFIL_04302 Transcriptional activator protein Anr
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_152 HflK protein 0.54 PfGW456L13_4071 Fumarate and nitrate reduction regulatory protein low > 87
Ralstonia solanacearum PSI07 0.34 RPSI07_RS18065 FtsH protease activity modulator HflK 0.38 RPSI07_RS17705 fumarate/nitrate reduction transcriptional regulator Fnr low > 81
Pseudomonas sp. SVBP6 0.34 COO64_RS17910 hflK FtsH protease activity modulator HflK 0.52 COO64_RS18640 fnrA Crp/Fnr family transcriptional regulator FnrA low > 93
Pseudomonas sp. S08-1 0.34 OH686_09460 HflK protein 0.53 OH686_02245 Fumarate and nitrate reduction regulatory protein low > 80
Pseudomonas putida KT2440 0.34 PP_4892 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex 0.52 PP_4265 DNA-binding transcriptional dual regulator low > 96
Pseudomonas stutzeri RCH2 0.34 Psest_0685 HflK protein 0.53 Psest_2538 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
Pseudomonas sp. BP01 0.34 JOY50_RS17240 hflK FtsH protease activity modulator HflK 0.52 JOY50_RS00125 fnrA Crp/Fnr family transcriptional regulator FnrA low > 84
Castellaniella sp019104865 MT123 0.33 ABCV34_RS02660 FtsH protease activity modulator HflK 0.34 ABCV34_RS06835 helix-turn-helix domain-containing protein
Ralstonia solanacearum IBSBF1503 0.33 RALBFv3_RS15310 FtsH protease activity modulator HflK 0.38 RALBFv3_RS15650 fumarate/nitrate reduction transcriptional regulator Fnr low > 76
Ralstonia solanacearum UW163 0.33 UW163_RS12775 FtsH protease activity modulator HflK 0.38 UW163_RS13110 fumarate/nitrate reduction transcriptional regulator Fnr
Hydrogenophaga sp. GW460-11-11-14-LB1 0.33 GFF4856 HflK protein 0.39 GFF4142 transcriptional regulator, Crp/Fnr family low > 90
Variovorax sp. SCN45 0.33 GFF1002 HflK protein 0.22 GFF6947 transcriptional regulator, Crp/Fnr family low > 127
Methylophilus sp. DMC18 0.32 GFF1223 hypothetical protein 0.38 GFF1089 Transcriptional activator protein Anr low > 43
Cupriavidus basilensis FW507-4G11 0.32 RR42_RS13105 membrane protein 0.40 RR42_RS12875 transcriptional regulator
Ralstonia sp. UNC404CL21Col 0.32 ABZR87_RS10950 FtsH protease activity modulator HflK 0.39 ABZR87_RS11180 fumarate/nitrate reduction transcriptional regulator Fnr low > 80
Herbaspirillum seropedicae SmR1 0.31 HSERO_RS14765 membrane protein 0.41 HSERO_RS16020 transcriptional regulator
Ralstonia solanacearum GMI1000 0.31 RS_RS06120 FtsH protease activity modulator HflK 0.38 RS_RS06430 fumarate/nitrate reduction transcriptional regulator Fnr low > 80
Kangiella aquimarina DSM 16071 0.31 B158DRAFT_1954 protease FtsH subunit HflK 0.56 B158DRAFT_1982 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases low > 40
Acidovorax sp. GW101-3H11 0.31 Ac3H11_1801 HflK protein 0.38 Ac3H11_975 transcriptional regulator, Crp/Fnr family
Rhodanobacter sp. FW510-T8 0.29 OKGIIK_06640 hflK FtsH protease activity modulator HflK 0.37 OKGIIK_00820 CRP-like protein Clp low > 52
Rhodanobacter sp000427505 FW510-R12 0.28 LRK53_RS09535 FtsH protease activity modulator HflK 0.35 LRK53_RS14515 cyclic nucleotide-binding domain-containing protein low > 59
Rhodanobacter denitrificans FW104-10B01 0.28 LRK54_RS00620 FtsH protease activity modulator HflK 0.35 LRK54_RS05830 helix-turn-helix domain-containing protein low > 59
Rhodanobacter denitrificans MT42 0.28 LRK55_RS00390 FtsH protease activity modulator HflK 0.35 LRK55_RS05585 helix-turn-helix domain-containing protein low > 63
Dyella japonica UNC79MFTsu3.2 0.27 ABZR86_RS08355 FtsH protease activity modulator HflK 0.25 ABZR86_RS04345 cyclic nucleotide-binding domain-containing protein low > 74
Rhodospirillum rubrum S1H 0.26 Rru_A2203 HflK (NCBI) 0.22 Rru_A3322 Transcriptional Regulator, Crp/Fnr family (NCBI)
Magnetospirillum magneticum AMB-1 0.25 AMB_RS17650 FtsH protease activity modulator HflK 0.22 AMB_RS22105 transcriptional regulator
Dinoroseobacter shibae DFL-12 0.25 Dshi_2736 HflK protein (RefSeq) 0.15 Dshi_0660 transcriptional regulator, Crp/Fnr family (RefSeq) low > 64
Xanthomonas campestris pv. campestris strain 8004 0.25 Xcc-8004.3955.1 HflK protein 0.22 Xcc-8004.2952.1 transcriptional regulator, Crp/Fnr family low > 74
Lysobacter sp. OAE881 0.24 ABIE51_RS06550 FtsH protease activity modulator HflK 0.37 ABIE51_RS03805 fumarate/nitrate reduction transcriptional regulator Fnr low > 62
Azospirillum sp. SherDot2 0.23 MPMX19_01251 Modulator of FtsH protease HflK 0.26 MPMX19_00212 Nitrogen fixation regulation protein FixK
Agrobacterium fabrum C58 0.22 Atu2045 HFLK protein 0.19 Atu1602 transcriptional activator, Crp family low > 89

Not shown: 6 genomes with orthologs for CSW01_01845 only; 12 genomes with orthologs for CSW01_07190 only