Conservation of cofitness between CSW01_01040 and CSW01_07075 in Vibrio cholerae E7946 ATCC 55056

85 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_01040 protein RarD 1.0 CSW01_07075 MFS transporter 0.69 11
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.62 GFF245 Protein rarD 0.38 GFF1593 Multidrug resistance protein B low > 78
Enterobacter asburiae PDN3 0.61 EX28DRAFT_4484 rarD protein 0.53 EX28DRAFT_2615 drug resistance transporter, EmrB/QacA subfamily low > 76
Klebsiella pneumoniae MKP103 0.61 KDGMDA_09720 EamA family transporter RarD 0.39 KDGMDA_02765 multidrug efflux MFS transporter permease subunit EmrB low > 95
Klebsiella michiganensis M5al 0.61 BWI76_RS01230 chloramphenicol resistance permease RarD 0.39 BWI76_RS22100 multidrug effux MFS transporter subunit EmrB low > 92
Serratia liquefaciens MT49 0.61 IAI46_00755 EamA family transporter RarD 0.36 IAI46_20005 multidrug efflux MFS transporter permease subunit EmrB low > 87
Escherichia coli Nissle 1917 0.61 ECOLIN_RS21920 EamA family transporter RarD 0.37 ECOLIN_RS14970 multidrug efflux MFS transporter permease subunit EmrB low > 55
Enterobacter sp. TBS_079 0.61 MPMX20_04461 Protein RarD 0.39 MPMX20_03564 Multidrug export protein EmrB low > 85
Escherichia coli BL21 0.60 ECD_03698 putative chloramphenical resistance permease 0.37 ECD_02541 multidrug efflux system protein low > 61
Escherichia coli ECOR27 0.60 NOLOHH_06505 rarD EamA family transporter RarD 0.37 NOLOHH_12615 emrB multidrug efflux MFS transporter permease subunit EmrB low > 76
Escherichia coli ECOR38 0.60 HEPCGN_13075 rarD EamA family transporter RarD 0.37 HEPCGN_19970 emrB multidrug efflux MFS transporter permease subunit EmrB low > 88
Escherichia coli BW25113 0.60 b3819 rarD predicted chloramphenical resistance permease (NCBI) 0.37 b2686 emrB multidrug efflux system protein (NCBI) 0.15 73
Escherichia fergusonii Becca 0.60 EFB2_04818 Protein RarD 0.37 EFB2_01242 Multidrug export protein EmrB low > 86
Escherichia coli ECRC62 0.60 BNILDI_05025 rarD EamA family transporter RarD 0.37 BNILDI_11175 emrB multidrug efflux MFS transporter permease subunit EmrB low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.60 OHPLBJKB_04232 Protein RarD 0.37 OHPLBJKB_01047 Multidrug export protein EmrB low > 74
Pectobacterium carotovorum WPP14 0.60 HER17_RS01380 EamA family transporter RarD 0.37 HER17_RS04460 multidrug efflux MFS transporter permease subunit EmrB low > 75
Escherichia coli ECRC99 0.60 KEDOAH_13775 rarD EamA family transporter RarD 0.37 KEDOAH_07360 emrB multidrug efflux MFS transporter permease subunit EmrB — —
Shewanella oneidensis MR-1 0.60 SO4243 rarD rarD protein (NCBI ptt file) 0.21 SO0525 drug resistance transporter, EmrB/QacA family protein (NCBI ptt file) low > 76
Escherichia coli ECRC98 0.60 JDDGAC_18000 rarD EamA family transporter RarD 0.37 JDDGAC_24440 emrB multidrug efflux MFS transporter permease subunit EmrB low > 87
Escherichia coli ECRC102 0.60 NIAGMN_12130 rarD EamA family transporter RarD 0.37 NIAGMN_18545 emrB multidrug efflux MFS transporter permease subunit EmrB low > 80
Escherichia coli ECRC100 0.60 OKFHMN_14375 rarD EamA family transporter RarD 0.37 OKFHMN_20775 emrB multidrug efflux MFS transporter permease subunit EmrB low > 79
Escherichia coli ECRC101 0.60 MCAODC_04880 rarD EamA family transporter RarD 0.37 MCAODC_11300 emrB multidrug efflux MFS transporter permease subunit EmrB low > 87
Rahnella sp. WP5 0.59 EX31_RS15195 EamA family transporter RarD 0.37 EX31_RS13660 multidrug efflux MFS transporter permease subunit EmrB low > 89
Erwinia tracheiphila SCR3 0.59 LU632_RS24110 rarD EamA family transporter RarD 0.23 LU632_RS09490 DHA2 family efflux MFS transporter permease subunit low > 73
Erwinia tracheiphila HP pepo 2.2 0.59 IJEDHG_08755 rarD EamA family transporter RarD 0.23 IJEDHG_19965 EmrB/QacA family drug resistance transporter low > 61
Dickeya dadantii 3937 0.58 DDA3937_RS19865 EamA family transporter RarD 0.37 DDA3937_RS16765 multidrug efflux MFS transporter permease subunit EmrB low > 74
Pantoea sp. MT58 0.57 IAI47_18375 EamA family transporter RarD 0.38 IAI47_04495 multidrug efflux MFS transporter permease subunit EmrB low > 76
Shewanella amazonensis SB2B 0.57 Sama_0332 rarD protein (RefSeq) 0.21 Sama_0403 drug resistance transporter, EmrB/QacA family protein (RefSeq) low > 62
Dickeya dianthicola 67-19 0.56 HGI48_RS20020 EamA family transporter RarD 0.38 HGI48_RS16835 multidrug efflux MFS transporter permease subunit EmrB low > 71
Shewanella loihica PV-4 0.56 Shew_3476 transporter DMT superfamily protein (RefSeq) 0.21 Shew_3405 EmrB/QacA family drug resistance transporter (RefSeq) low > 60
Dickeya dianthicola ME23 0.56 DZA65_RS21060 EamA family transporter RarD 0.38 DZA65_RS17910 multidrug efflux MFS transporter permease subunit EmrB low > 75
Pantoea agglomerans CFBP13505 P0401 0.56 PagCFBP13505_RS15355 EamA family transporter RarD 0.38 PagCFBP13505_RS14490 multidrug efflux MFS transporter permease subunit EmrB low > 74
Pseudomonas fluorescens FW300-N2E3 0.42 AO353_07550 chloramphenical resistance permease RarD 0.37 AO353_27840 multidrug resistance protein B low > 101
Pseudomonas simiae WCS417 0.42 PS417_26030 chloramphenical resistance permease RarD 0.38 PS417_16910 multidrug resistance protein B low > 88
Pseudomonas fluorescens SBW25 0.42 PFLU_RS27675 EamA family transporter RarD 0.38 PFLU_RS18895 DHA2 family efflux MFS transporter permease subunit low > 109
Pseudomonas fluorescens FW300-N1B4 0.42 Pf1N1B4_2480 Protein rarD 0.37 Pf1N1B4_4002 Inner membrane component of tripartite multidrug resistance system low > 87
Pseudomonas fluorescens SBW25-INTG 0.42 PFLU_RS27675 EamA family transporter RarD 0.38 PFLU_RS18895 DHA2 family efflux MFS transporter permease subunit low > 109
Pseudomonas sp. DMC3 0.42 GFF81 Protein RarD 0.37 GFF1488 Multidrug export protein EmrB low > 89
Pseudomonas fluorescens GW456-L13 0.42 PfGW456L13_1142 Protein rarD 0.37 PfGW456L13_2606 Inner membrane component of tripartite multidrug resistance system low > 87
Pseudomonas fluorescens FW300-N2E2 0.42 Pf6N2E2_4754 Protein rarD 0.37 Pf6N2E2_149 Inner membrane component of tripartite multidrug resistance system low > 103
Pseudomonas sp. RS175 0.42 PFR28_04108 Protein RarD 0.37 PFR28_02747 Multidrug export protein EmrB low > 88
Pseudomonas putida KT2440 0.42 PP_0358 conserved membrane protein of unknown function 0.38 PP_3548 multidrug efflux transport system - permease subunit low > 96
Pseudomonas sp. BP01 0.42 JOY50_RS17910 rarD EamA family transporter RarD 0.38 JOY50_RS28120 DHA2 family efflux MFS transporter permease subunit low > 84
Pseudomonas segetis P6 0.42 MPMX49_00754 Protein RarD 0.38 MPMX49_02243 Multidrug export protein EmrB low > 75
Pseudomonas aeruginosa MRSN321 0.41 DY961_RS22430 rarD;go_component=plasma EamA family transporter RarD 0.36 DY961_RS11645 DHA2 family efflux MFS transporter permease subunit low > 100
Pseudomonas aeruginosa PA14 0.41 IKLFDK_23000 EamA family transporter RarD 0.36 IKLFDK_27690 MFS transporter low > 98
Pseudomonas aeruginosa PUPa3 0.41 DQ20_RS36895 rarD;go_component=plasma EamA family transporter RarD 0.36 DQ20_RS50455 DHA2 family efflux MFS transporter permease subunit low > 101
Pseudomonas fluorescens FW300-N2C3 0.40 AO356_14110 Putative D-serine transporter (from data) 0.38 AO356_01025 multidrug resistance protein B low > 104
Paraburkholderia sabiae LMG 24235 0.40 QEN71_RS26035 EamA family transporter RarD 0.38 QEN71_RS23085 DHA2 family efflux MFS transporter permease subunit low > 153
Cupriavidus basilensis FW507-4G11 0.40 RR42_RS20410 transporter 0.39 RR42_RS12830 multidrug resistance protein B low > 128
Desulfovibrio vulgaris Miyazaki F 0.40 DvMF_2967 RarD protein, DMT superfamily transporter (RefSeq) 0.26 DvMF_1099 drug resistance transporter, EmrB/QacA subfamily (RefSeq) low > 51
Pseudomonas lactucae CFBP13502 0.39 GEMAOFIL_05327 Protein RarD 0.37 GEMAOFIL_03697 Multidrug export protein EmrB low > 96
Pseudomonas syringae pv. syringae B728a 0.38 Psyr_4698 RarD protein 0.37 Psyr_1731 Drug resistance transporter EmrB/QacA subfamily low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.38 Psyr_4698 RarD protein 0.37 Psyr_1731 Drug resistance transporter EmrB/QacA subfamily low > 86
Pseudomonas sp. SVBP6 0.38 COO64_RS22750 rarD EamA family transporter RarD 0.37 COO64_RS08900 DHA2 family efflux MFS transporter permease subunit low > 93
Ralstonia solanacearum GMI1000 0.37 RS_RS02855 EamA family transporter RarD 0.55 RS_RS09355 MFS transporter 0.36 10
Ralstonia sp. UNC404CL21Col 0.36 ABZR87_RS08060 EamA family transporter RarD 0.41 ABZR87_RS11225 DHA2 family efflux MFS transporter permease subunit low > 80
Magnetospirillum magneticum AMB-1 0.36 AMB_RS06360 EamA family transporter RarD 0.20 AMB_RS20240 MFS transporter low > 64
Pseudomonas orientalis W4I3 0.36 QF045_RS00440 EamA family transporter RarD 0.38 QF045_RS18620 DHA2 family efflux MFS transporter permease subunit low > 93
Pseudomonas sp. S08-1 0.36 OH686_10385 Uncharacterized inner membrane protein RarD 0.21 OH686_04570 Inner-membrane proton/drug antiporter (MSF type) of tripartite multidrug efflux system low > 80
Lysobacter sp. OAE881 0.35 ABIE51_RS03205 EamA family transporter RarD 0.39 ABIE51_RS07705 DHA2 family efflux MFS transporter permease subunit low > 62
Sinorhizobium meliloti 1021 0.35 SMc02545 hypothetical protein 0.17 SMc03167 multidrug efflux system protein low > 103
Azospirillum sp. SherDot2 0.35 MPMX19_00476 Protein RarD 0.22 MPMX19_05353 Fatty acid resistance protein FarB low > 112
Ralstonia solanacearum IBSBF1503 0.35 RALBFv3_RS12170 EamA family transporter RarD 0.41 RALBFv3_RS15695 MFS transporter low > 76
Ralstonia solanacearum UW163 0.35 UW163_RS01440 EamA family transporter RarD 0.17 UW163_RS07870 MFS transporter — —
Sphingomonas koreensis DSMZ 15582 0.34 Ga0059261_3478 rarD protein 0.23 Ga0059261_4005 drug resistance transporter, EmrB/QacA subfamily low > 68
Herbaspirillum seropedicae SmR1 0.34 HSERO_RS23555 membrane protein 0.64 HSERO_RS16355 DSBA oxidoreductase low > 78
Rhizobium sp. OAE497 0.34 ABIE40_RS06215 EamA family transporter RarD 0.23 ABIE40_RS21925 DHA2 family efflux MFS transporter permease subunit low > 107
Acidovorax sp. GW101-3H11 0.34 Ac3H11_4000 RarD protein, DMT superfamily transporter 0.40 Ac3H11_2352 Inner membrane component of tripartite multidrug resistance system low > 79
Sphingobium sp. HT1-2 0.34 GFF3086 Uncharacterized inner membrane protein RarD 0.46 GFF3801 Multidrug efflux system EmrAB-OMF, inner-membrane proton/drug antiporter EmrB (MFS type) low > 95
Caulobacter crescentus NA1000 Δfur 0.33 CCNA_00254 RarD family membrane permease 0.19 CCNA_03831 major facilitator superfamily transporter low > 67
Caulobacter crescentus NA1000 0.33 CCNA_00254 RarD family membrane permease 0.19 CCNA_03831 major facilitator superfamily transporter low > 66
Agrobacterium fabrum C58 0.33 Atu1068 hypothetical protein 0.21 Atu4479 MFS permease low > 89
Ralstonia solanacearum PSI07 0.32 RPSI07_RS21160 EamA family transporter RarD 0.40 RPSI07_RS17660 MFS transporter low > 81
Xanthomonas campestris pv. campestris strain 8004 0.32 Xcc-8004.4969.1 RarD protein, chloamphenicol sensitive 0.35 Xcc-8004.3524.1 Inner membrane component of tripartite multidrug resistance system low > 74
Brevundimonas sp. GW460-12-10-14-LB2 0.32 A4249_RS12695 EamA family transporter RarD 0.20 A4249_RS14985 DHA2 family efflux MFS transporter permease subunit low > 48
Rhodospirillum rubrum S1H 0.31 Rru_A0706 RarD protein (NCBI) 0.37 Rru_A0858 Drug resistance transporter EmrB/QacA subfamily (NCBI) low > 58
Burkholderia phytofirmans PsJN 0.20 BPHYT_RS34860 chemotaxis protein 0.42 BPHYT_RS19670 DSBA oxidoreductase low > 109
Castellaniella sp019104865 MT123 0.18 ABCV34_RS08310 EamA family transporter RarD 0.40 ABCV34_RS05950 DHA2 family efflux MFS transporter permease subunit low > 48
Paraburkholderia bryophila 376MFSha3.1 0.18 H281DRAFT_03622 chloramphenicol-sensitive protein RarD 0.41 H281DRAFT_02341 MFS transporter, DHA2 family, multidrug resistance protein low > 103
Acinetobacter baumannii LAC-4 0.17 RR41_RS04955 EamA family transporter RarD 0.50 RR41_RS14740 DHA2 family efflux MFS transporter permease subunit low > 55
Hydrogenophaga sp. GW460-11-11-14-LB1 0.17 GFF1172 Chloramphenicol-sensitive protein rarD 0.41 GFF3757 Inner membrane component of tripartite multidrug resistance system low > 90
Acinetobacter radioresistens SK82 0.16 MPMX26_02140 Protein RarD 0.47 MPMX26_02394 Multidrug export protein EmrB low > 36
Paraburkholderia graminis OAS925 0.16 ABIE53_004634 chloramphenicol-sensitive protein RarD 0.42 ABIE53_000311 DHA2 family multidrug resistance protein low > 113
Pontibacter actiniarum KMM 6156, DSM 19842 0.14 CA264_15360 permease 0.25 CA264_07170 MFS transporter low > 74
Pedobacter sp. GW460-11-11-14-LB5 0.13 CA265_RS22830 permease 0.24 CA265_RS21345 MFS transporter low > 88

Not shown: 8 genomes with orthologs for CSW01_01040 only; 19 genomes with orthologs for CSW01_07075 only