| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_14090 | | NAD(P)-dependent oxidoreductase | 1.0 | CSW01_06415 | | MBL fold metallo-hydrolase | 0.64 | 7 |
| Cupriavidus basilensis FW507-4G11 | 0.55 | RR42_RS31100 | | oxidoreductase | 0.55 | RR42_RS19750 | | MBL fold metallo-hydrolase | low | > 128 |
| Rhodopseudomonas palustris CGA009 | 0.54 | TX73_010170 | | NAD(P)-dependent oxidoreductase | 0.50 | TX73_002945 | | MBL fold metallo-hydrolase | low | > 86 |
| Shewanella loihica PV-4 | 0.54 | Shew_1609 | | 6-phosphogluconate dehydrogenase, NAD-binding (RefSeq) | 0.60 | Shew_2269 | | beta-lactamase domain-containing protein (RefSeq) | low | > 60 |
| Rhizobium sp. OAE497 | 0.54 | ABIE40_RS10680 | | NAD(P)-dependent oxidoreductase | 0.50 | ABIE40_RS12965 | | MBL fold metallo-hydrolase | low | > 107 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.53 | GFF2719 | | 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) | 0.60 | GFF1871 | | Hypothetical metal-binding enzyme, YcbL homolog | — | — |
| Bosea sp. OAE506 | 0.53 | ABIE41_RS21160 | | NAD(P)-dependent oxidoreductase | 0.46 | ABIE41_RS00100 | | MBL fold metallo-hydrolase | — | — |
| Sinorhizobium meliloti 1021 | 0.52 | SMc00133 | | oxidoreductase | 0.48 | SMc01587 | | hypothetical protein | low | > 103 |
| Marinobacter adhaerens HP15 | 0.51 | HP15_1515 | | 6-phosphogluconate dehydrogenase domain protein | 0.62 | HP15_1191 | | metallo-beta-lactamase family protein | low | > 73 |
| Acidovorax sp. GW101-3H11 | 0.51 | Ac3H11_4470 | | 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) | 0.48 | Ac3H11_3348 | | Hypothetical metal-binding enzyme, YcbL homolog | — | — |
| Shewanella sp. ANA-3 | 0.51 | Shewana3_2554 | | 6-phosphogluconate dehydrogenase, NAD-binding (RefSeq) | 0.61 | Shewana3_1493 | | beta-lactamase domain-containing protein (RefSeq) | low | > 73 |
| Shewanella amazonensis SB2B | 0.50 | Sama_1975 | | 2-hydroxy-3-oxopropionate reductase (RefSeq) | 0.55 | Sama_2142 | | metallo-beta-lactamase family protein (RefSeq) | low | > 62 |
| Alteromonas macleodii MIT1002 | 0.50 | MIT1002_01976 | | 2-hydroxy-3-oxopropionate reductase | 0.54 | MIT1002_03450 | | Beta-lactamase hydrolase-like protein | low | > 70 |
| Pseudomonas sp. S08-1 | 0.50 | OH686_02015 | | 2-hydroxy-3-oxopropionate reductase | 0.31 | OH686_06295 | | MBL-fold metallo-hydrolase superfamily | low | > 80 |
| Caulobacter crescentus NA1000 | 0.50 | CCNA_01645 | | 3-hydroxyisobutyrate dehydrogenase | 0.53 | CCNA_01241 | | Zn-dependent hydrolase, glyoxalase II family | low | > 66 |
| Caulobacter crescentus NA1000 Δfur | 0.50 | CCNA_01645 | | 3-hydroxyisobutyrate dehydrogenase | 0.53 | CCNA_01241 | | Zn-dependent hydrolase, glyoxalase II family | low | > 67 |
| Shewanella oneidensis MR-1 | 0.50 | SO2771 | garR | 2-hydroxy-3-oxopropionate reductase (NCBI ptt file) | 0.61 | SO3054 | | metallo-beta-lactamase family protein (NCBI ptt file) | low | > 76 |
| Pseudomonas segetis P6 | 0.49 | MPMX49_02338 | | 2-hydroxy-3-oxopropionate reductase | 0.33 | MPMX49_03689 | | Hydroxyacylglutathione hydrolase GloC | low | > 75 |
| Pseudomonas aeruginosa PA14 | 0.49 | IKLFDK_07540 | | oxidoreductase | 0.33 | IKLFDK_03655 | | MBL fold metallo-hydrolase | low | > 98 |
| Sphingobium sp. HT1-2 | 0.49 | GFF1491 | | 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) | 0.49 | GFF667 | | Hypothetical metal-binding enzyme, YcbL homolog | low | > 95 |
| Pseudomonas aeruginosa MRSN321 | 0.49 | DY961_RS19525 | | NAD(P)-dependent oxidoreductase | 0.33 | DY961_RS08335 | | MBL fold metallo-hydrolase | low | > 100 |
| Pseudomonas aeruginosa PUPa3 | 0.48 | DQ20_RS53640 | | NAD(P)-dependent oxidoreductase | 0.33 | DQ20_RS44490 | | MBL fold metallo-hydrolase | low | > 101 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.43 | A4249_RS06070 | | NAD(P)-dependent oxidoreductase | 0.53 | A4249_RS06505 | | MBL fold metallo-hydrolase | low | > 48 |
| Escherichia coli ECRC102 | 0.31 | NIAGMN_16130 | garR | 2-hydroxy-3-oxopropionate reductase | 0.59 | NIAGMN_03110 | gloC | hydroxyacylglutathione hydrolase GloC | low | > 80 |
| Escherichia coli BW25113 | 0.31 | b3125 | garR | tartronate semialdehyde reductase (RefSeq) | 0.59 | b0927 | ycbL | predicted metal-binding enzyme (NCBI) | low | > 76 |
| Escherichia coli ECOR38 | 0.31 | HEPCGN_17205 | garR | 2-hydroxy-3-oxopropionate reductase | 0.60 | HEPCGN_23135 | gloC | hydroxyacylglutathione hydrolase GloC | low | > 88 |
| Dechlorosoma suillum PS | 0.31 | Dsui_3436 | | beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase | 0.57 | Dsui_3107 | | Zn-dependent hydrolase, glyoxylase | low | > 51 |
| Escherichia coli ECRC98 | 0.31 | JDDGAC_22000 | garR | 2-hydroxy-3-oxopropionate reductase | 0.59 | JDDGAC_09000 | gloC | hydroxyacylglutathione hydrolase GloC | low | > 87 |
| Escherichia coli ECRC62 | 0.31 | BNILDI_01380 | garR | 2-hydroxy-3-oxopropionate reductase | 0.59 | BNILDI_20205 | gloC | hydroxyacylglutathione hydrolase GloC | low | > 75 |
| Escherichia coli ECRC101 | 0.31 | MCAODC_08880 | garR | 2-hydroxy-3-oxopropionate reductase | 0.59 | MCAODC_24780 | gloC | hydroxyacylglutathione hydrolase GloC | low | > 87 |
| Escherichia coli ECRC99 | 0.31 | KEDOAH_09780 | garR | 2-hydroxy-3-oxopropionate reductase | 0.59 | KEDOAH_22345 | gloC | hydroxyacylglutathione hydrolase GloC | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.31 | OHPLBJKB_00578 | | 2-hydroxy-3-oxopropionate reductase | 0.59 | OHPLBJKB_02740 | | Hydroxyacylglutathione hydrolase GloC | low | > 74 |
| Escherichia coli Nissle 1917 | 0.31 | ECOLIN_RS17960 | | 2-hydroxy-3-oxopropionate reductase | 0.59 | ECOLIN_RS04905 | | hydroxyacylglutathione hydrolase GloC | low | > 55 |
| Escherichia coli BL21 | 0.31 | ECD_02990 | | tartronate semialdehyde reductase | 0.59 | ECD_00931 | | putative metal-binding enzyme | low | > 61 |
| Escherichia coli ECOR27 | 0.31 | NOLOHH_10150 | garR | 2-hydroxy-3-oxopropionate reductase | 0.59 | NOLOHH_21950 | gloC | hydroxyacylglutathione hydrolase GloC | low | > 76 |
| Escherichia coli ECRC100 | 0.31 | OKFHMN_18370 | garR | 2-hydroxy-3-oxopropionate reductase | 0.59 | OKFHMN_05390 | gloC | hydroxyacylglutathione hydrolase GloC | low | > 79 |
| Rahnella sp. WP5 | 0.30 | EX31_RS07980 | | 2-hydroxy-3-oxopropionate reductase | 0.54 | EX31_RS18150 | | MBL fold metallo-hydrolase | low | > 89 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.30 | GFF1536 | | 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) | 0.59 | GFF3684 | | Hypothetical metal-binding enzyme, YcbL homolog | low | > 78 |
| Klebsiella pneumoniae MKP103 | 0.30 | KDGMDA_05690 | | 2-hydroxy-3-oxopropionate reductase | 0.61 | KDGMDA_18065 | | Hydroxyacylglutathione hydrolase GloC | low | > 95 |
| Escherichia fergusonii Becca | 0.29 | EFB2_00694 | | 2-hydroxy-3-oxopropionate reductase | 0.59 | EFB2_03137 | | Hydroxyacylglutathione hydrolase GloC | low | > 86 |
| Klebsiella michiganensis M5al | 0.29 | BWI76_RS24825 | | 2-hydroxy-3-oxopropionate reductase | 0.60 | BWI76_RS09865 | | MBL fold hydrolase | low | > 92 |
| Dickeya dadantii 3937 | 0.29 | DDA3937_RS17035 | | 2-hydroxy-3-oxopropionate reductase | 0.58 | DDA3937_RS12920 | | MBL fold metallo-hydrolase | low | > 74 |
| Dickeya dianthicola ME23 | 0.28 | DZA65_RS18165 | | 2-hydroxy-3-oxopropionate reductase | 0.57 | DZA65_RS13455 | | MBL fold metallo-hydrolase | low | > 75 |
| Pantoea sp. MT58 | 0.28 | IAI47_04100 | | 2-hydroxy-3-oxopropionate reductase | 0.56 | IAI47_12770 | | MBL fold metallo-hydrolase | low | > 76 |
| Enterobacter sp. TBS_079 | 0.28 | MPMX20_04033 | | 2-hydroxy-3-oxopropionate reductase | 0.59 | MPMX20_01585 | | Hydroxyacylglutathione hydrolase GloC | low | > 85 |
| Enterobacter asburiae PDN3 | 0.28 | EX28DRAFT_3182 | | 2-hydroxy-3-oxopropionate reductase | 0.59 | EX28DRAFT_2009 | | Zn-dependent hydrolases, including glyoxylases | low | > 76 |
| Erwinia tracheiphila HP pepo 2.2 | 0.28 | IJEDHG_17355 | garR | 2-hydroxy-3-oxopropionate reductase | 0.56 | IJEDHG_20400 | | Hydroxyacylglutathione hydrolase GloC | low | > 61 |
| Erwinia tracheiphila SCR3 | 0.28 | LU632_RS06330 | garR | 2-hydroxy-3-oxopropionate reductase | 0.56 | LU632_RS09895 | | MBL fold metallo-hydrolase | low | > 73 |
| Pantoea agglomerans CFBP13505 P0401 | 0.28 | PagCFBP13505_RS16870 | | 2-hydroxy-3-oxopropionate reductase | 0.55 | PagCFBP13505_RS04560 | | MBL fold metallo-hydrolase | low | > 74 |
| Dickeya dianthicola 67-19 | 0.28 | HGI48_RS17090 | | 2-hydroxy-3-oxopropionate reductase | 0.58 | HGI48_RS12995 | | MBL fold metallo-hydrolase | low | > 71 |
| Ralstonia solanacearum IBSBF1503 | 0.28 | RALBFv3_RS04620 | | NAD(P)-dependent oxidoreductase | 0.53 | RALBFv3_RS08505 | | MBL fold metallo-hydrolase | — | — |
| Ralstonia solanacearum UW163 | 0.28 | UW163_RS09050 | | NAD(P)-dependent oxidoreductase | 0.53 | UW163_RS05105 | | MBL fold metallo-hydrolase | — | — |
| Ralstonia sp. UNC404CL21Col | 0.28 | ABZR87_RS00230 | | NAD(P)-dependent oxidoreductase | 0.53 | ABZR87_RS03825 | | MBL fold metallo-hydrolase | low | > 80 |
| Paraburkholderia sabiae LMG 24235 | 0.28 | QEN71_RS32505 | | 2-hydroxy-3-oxopropionate reductase | 0.56 | QEN71_RS00645 | | MBL fold metallo-hydrolase | low | > 153 |
| Ralstonia solanacearum PSI07 | 0.28 | RPSI07_RS12755 | | NAD(P)-dependent oxidoreductase | 0.54 | RPSI07_RS08720 | | MBL fold metallo-hydrolase | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.27 | H281DRAFT_05314 | | 2-hydroxy-3-oxopropionate reductase | 0.57 | H281DRAFT_02154 | | Glyoxylase, beta-lactamase superfamily II | low | > 103 |
| Paraburkholderia graminis OAS925 | 0.27 | ABIE53_006511 | | 2-hydroxy-3-oxopropionate reductase | 0.57 | ABIE53_000468 | | hydroxyacylglutathione hydrolase | — | — |
| Burkholderia phytofirmans PsJN | 0.27 | BPHYT_RS24130 | | tartronate semialdehyde reductase | 0.55 | BPHYT_RS01930 | | hypothetical protein | — | — |
| Xanthobacter sp. DMC5 | 0.27 | GFF1957 | | 2-hydroxy-3-oxopropionate reductase | 0.48 | GFF3817 | | Hydroxyacylglutathione hydrolase GloC | — | — |
| Desulfovibrio vulgaris Miyazaki F | 0.27 | DvMF_2927 | garR | tartronate semialdehyde reductase (RefSeq) | 0.26 | DvMF_2853 | | beta-lactamase domain protein (RefSeq) | low | > 51 |
| Azospirillum brasilense Sp245 | 0.27 | AZOBR_RS07955 | | tartronate semialdehyde reductase | 0.55 | AZOBR_RS19250 | | hypothetical protein | — | — |
| Ralstonia solanacearum GMI1000 | 0.26 | RS_RS16450 | | 2-hydroxy-3-oxopropionate reductase | 0.54 | RS_RS16370 | | MBL fold metallo-hydrolase | — | — |
| Pseudomonas orientalis W4I3 | 0.26 | QF045_RS11500 | | 2-hydroxy-3-oxopropionate reductase | 0.33 | QF045_RS07550 | | MBL fold metallo-hydrolase | 0.68 | 9 |
| Pectobacterium carotovorum WPP14 | 0.26 | HER17_RS04095 | | 2-hydroxy-3-oxopropionate reductase | 0.59 | HER17_RS12035 | | MBL fold metallo-hydrolase | low | > 75 |
| Pseudomonas simiae WCS417 | 0.26 | PS417_08800 | | tartronate semialdehyde reductase | 0.32 | PS417_04560 | | beta-lactamase | — | — |
| Pseudomonas stutzeri RCH2 | 0.25 | Psest_1179 | | 2-hydroxy-3-oxopropionate reductase | 0.33 | Psest_3219 | | Zn-dependent hydrolases, including glyoxylases | low | > 67 |
| Pseudomonas fluorescens SBW25 | 0.25 | PFLU_RS08860 | | 2-hydroxy-3-oxopropionate reductase | 0.32 | PFLU_RS04625 | | MBL fold metallo-hydrolase | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.25 | PFLU_RS08860 | | 2-hydroxy-3-oxopropionate reductase | 0.32 | PFLU_RS04625 | | MBL fold metallo-hydrolase | low | > 109 |
| Pseudomonas lactucae CFBP13502 | 0.25 | GEMAOFIL_01891 | | 2-hydroxy-3-oxopropionate reductase | 0.33 | GEMAOFIL_01115 | | Hydroxyacylglutathione hydrolase GloC | low | > 96 |
| Pseudomonas sp. DMC3 | 0.25 | GFF2501 | | 2-hydroxy-3-oxopropionate reductase | 0.33 | GFF4448 | | Hydroxyacylglutathione hydrolase GloC | low | > 89 |
| Pseudomonas fluorescens GW456-L13 | 0.25 | PfGW456L13_4297 | | 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) | 0.34 | PfGW456L13_1623 | | Hypothetical metal-binding enzyme, YcbL homolog | low | > 87 |
| Agrobacterium fabrum C58 | 0.25 | Atu2737 | | oxidoredutase | 0.48 | Atu2201 | | hydrolase | low | > 89 |
| Pseudomonas sp. BP01 | 0.25 | JOY50_RS00360 | | 2-hydroxy-3-oxopropionate reductase | 0.31 | JOY50_RS19395 | | MBL fold metallo-hydrolase | low | > 84 |
| Pseudomonas putida KT2440 | 0.25 | PP_4299 | | tartronate semialdehyde reductase | 0.31 | PP_0772 | | Metallo-beta-lactamase family protein | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.24 | AO353_01930 | | 2-hydroxy-3-oxopropionate reductase | 0.33 | AO353_15160 | | MBL fold metallo-hydrolase | low | > 101 |
| Azospirillum sp. SherDot2 | 0.23 | MPMX19_05813 | | 2-hydroxy-3-oxopropionate reductase | 0.56 | MPMX19_04818 | | Hydroxyacylglutathione hydrolase GloC | low | > 112 |
| Pseudomonas sp. SVBP6 | 0.23 | COO64_RS25875 | | 2-hydroxy-3-oxopropionate reductase | 0.33 | COO64_RS03445 | | MBL fold metallo-hydrolase | low | > 93 |
| Acinetobacter radioresistens SK82 | 0.23 | MPMX26_01549 | | 3-hydroxyisobutyrate dehydrogenase | 0.47 | MPMX26_00296 | | Hydroxyacylglutathione hydrolase GloC | — | — |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.23 | CA265_RS01080 | | 6-phosphogluconate dehydrogenase | 0.28 | CA265_RS19735 | | MBL fold hydrolase | low | > 88 |
| Acinetobacter baumannii LAC-4 | 0.23 | RR41_RS18340 | | 3-hydroxyisobutyrate dehydrogenase | 0.48 | RR41_RS17080 | | MBL fold metallo-hydrolase | low | > 55 |
| Magnetospirillum magneticum AMB-1 | 0.22 | AMB_RS18155 | | 3-hydroxyisobutyrate dehydrogenase | 0.20 | AMB_RS06135 | | MBL fold metallo-hydrolase | low | > 64 |
| Pseudomonas fluorescens FW300-N1B4 | 0.22 | Pf1N1B4_3659 | | 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) | 0.33 | Pf1N1B4_2963 | | Hypothetical metal-binding enzyme, YcbL homolog | — | — |
| Mycobacterium tuberculosis H37Rv | 0.18 | Rv0751c | | Probable 3-hydroxyisobutyrate dehydrogenase MmsB (hibadh) | 0.24 | Rv2581c | | Possible glyoxalase II (hydroxyacylglutathione hydrolase) (GLX II) | low | > 58 |
| Sphingomonas koreensis DSMZ 15582 | 0.18 | Ga0059261_3686 | | 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) | 0.50 | Ga0059261_2228 | | Zn-dependent hydrolases, including glyoxylases | 0.41 | 11 |
| Serratia liquefaciens MT49 | 0.17 | IAI46_07605 | | NAD(P)-dependent oxidoreductase | 0.58 | IAI46_08745 | | MBL fold metallo-hydrolase | low | > 87 |
| Rhodospirillum rubrum S1H | 0.15 | Rru_A1833 | | 3-hydroxyisobutyrate dehydrogenase (NCBI) | 0.55 | Rru_A1522 | | Beta-lactamase-like (NCBI) | — | — |
| Erwinia amylovora T8 | 0.13 | OLJFJH_17300 | | 3-hydroxyisobutyrate dehydrogenase | 0.57 | OLJFJH_16050 | | Hydroxyacylglutathione hydrolase GloC | 0.28 | 21 |
Not shown: 20 genomes with orthologs for CSW01_14090 only; 11 genomes with orthologs for CSW01_06415 only