| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_11730 | | 2-dehydropantoate 2-reductase | 1.0 | CSW01_02455 | | YggS family pyridoxal phosphate enzyme | 0.86 | 1 |
| Rahnella sp. WP5 | 0.38 | EX31_RS22180 | | 2-dehydropantoate 2-reductase | 0.57 | EX31_RS02685 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 89 |
| Enterobacter sp. TBS_079 | 0.36 | MPMX20_01016 | | 2-dehydropantoate 2-reductase | 0.56 | MPMX20_03809 | | Pyridoxal phosphate homeostasis protein | low | > 85 |
| Serratia liquefaciens MT49 | 0.35 | IAI46_04950 | | 2-dehydropantoate 2-reductase | 0.56 | IAI46_21410 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 87 |
| Escherichia coli ECRC101 | 0.35 | MCAODC_27620 | panE | 2-dehydropantoate 2-reductase | 0.58 | MCAODC_09775 | yggS | pyridoxal phosphate homeostasis protein | low | > 87 |
| Escherichia coli ECRC102 | 0.35 | NIAGMN_06450 | panE | 2-dehydropantoate 2-reductase | 0.58 | NIAGMN_17020 | yggS | pyridoxal phosphate homeostasis protein | low | > 80 |
| Escherichia coli ECRC100 | 0.35 | OKFHMN_08395 | panE | 2-dehydropantoate 2-reductase | 0.58 | OKFHMN_19255 | yggS | pyridoxal phosphate homeostasis protein | low | > 79 |
| Escherichia coli BW25113 | 0.35 | b0425 | panE | 2-dehydropantoate 2-reductase (NCBI) | 0.58 | b2951 | yggS | predicted enzyme (NCBI) | low | > 76 |
| Escherichia coli ECRC98 | 0.35 | JDDGAC_12050 | panE | 2-dehydropantoate 2-reductase | 0.58 | JDDGAC_22885 | yggS | pyridoxal phosphate homeostasis protein | low | > 87 |
| Escherichia coli ECRC99 | 0.35 | KEDOAH_19570 | panE | 2-dehydropantoate 2-reductase | 0.58 | KEDOAH_08885 | yggS | pyridoxal phosphate homeostasis protein | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.35 | OHPLBJKB_03251 | | 2-dehydropantoate 2-reductase | 0.58 | OHPLBJKB_00765 | | Pyridoxal phosphate homeostasis protein | low | > 74 |
| Enterobacter asburiae PDN3 | 0.35 | EX28DRAFT_2546 | | 2-dehydropantoate 2-reductase | 0.59 | EX28DRAFT_2989 | | pyridoxal phosphate enzyme, YggS family | 0.58 | 55 |
| Escherichia coli ECOR38 | 0.35 | HEPCGN_07025 | panE | 2-dehydropantoate 2-reductase | 0.58 | HEPCGN_18560 | yggS | pyridoxal phosphate homeostasis protein | low | > 88 |
| Escherichia coli ECRC62 | 0.35 | BNILDI_22760 | panE | 2-dehydropantoate 2-reductase | 0.58 | BNILDI_09705 | yggS | pyridoxal phosphate homeostasis protein | low | > 75 |
| Escherichia coli BL21 | 0.35 | ECD_00373 | | 2-dehydropantoate reductase, NADPH-specific | 0.58 | ECD_02781 | | UPF0001 family protein, PLP-binding | low | > 61 |
| Escherichia coli ECOR27 | 0.35 | NOLOHH_01345 | panE | 2-dehydropantoate 2-reductase | 0.58 | NOLOHH_11125 | yggS | pyridoxal phosphate homeostasis protein | low | > 76 |
| Escherichia fergusonii Becca | 0.35 | EFB2_03632 | | 2-dehydropantoate 2-reductase | 0.58 | EFB2_00951 | | Pyridoxal phosphate homeostasis protein | low | > 86 |
| Klebsiella pneumoniae MKP103 | 0.35 | KDGMDA_14500 | | 2-dehydropantoate 2-reductase | 0.55 | KDGMDA_04615 | | YggS family pyridoxal phosphate enzyme | low | > 95 |
| Pectobacterium carotovorum WPP14 | 0.34 | HER17_RS15910 | | 2-dehydropantoate 2-reductase | 0.61 | HER17_RS03810 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 75 |
| Escherichia coli Nissle 1917 | 0.34 | ECOLIN_RS02560 | | 2-dehydropantoate 2-reductase | 0.58 | ECOLIN_RS16415 | | pyridoxal phosphate homeostasis protein | low | > 55 |
| Klebsiella michiganensis M5al | 0.34 | BWI76_RS06405 | | 2-dehydropantoate 2-reductase | 0.60 | BWI76_RS24100 | | YggS family pyridoxal phosphate enzyme | low | > 92 |
| Dickeya dianthicola ME23 | 0.34 | DZA65_RS05940 | | 2-dehydropantoate 2-reductase | 0.61 | DZA65_RS18435 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 75 |
| Dickeya dianthicola 67-19 | 0.33 | HGI48_RS05615 | | 2-dehydropantoate 2-reductase | 0.61 | HGI48_RS17345 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 71 |
| Pantoea agglomerans CFBP13505 P0401 | 0.32 | PagCFBP13505_RS10480 | | 2-dehydropantoate 2-reductase | 0.59 | PagCFBP13505_RS16100 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 74 |
| Pantoea sp. MT58 | 0.32 | IAI47_14715 | | 2-dehydropantoate 2-reductase | 0.58 | IAI47_03595 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 76 |
| Dickeya dadantii 3937 | 0.32 | DDA3937_RS05555 | | 2-dehydropantoate 2-reductase | 0.62 | DDA3937_RS17300 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 74 |
| Erwinia tracheiphila HP pepo 2.2 | 0.32 | IJEDHG_16335 | panE | 2-dehydropantoate 2-reductase | 0.55 | IJEDHG_03450 | | YggS family pyridoxal phosphate enzyme | low | > 61 |
| Erwinia tracheiphila SCR3 | 0.32 | LU632_RS18455 | panE | 2-dehydropantoate 2-reductase | 0.55 | LU632_RS05460 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 73 |
| Erwinia amylovora T8 | 0.32 | OLJFJH_18040 | | 2-dehydropantoate 2-reductase | 0.55 | OLJFJH_08530 | | YggS family pyridoxal phosphate enzyme | low | > 58 |
| Shewanella sp. ANA-3 | 0.32 | Shewana3_0780 | | 2-dehydropantoate 2-reductase (RefSeq) | 0.56 | Shewana3_1194 | | hypothetical protein (RefSeq) | low | > 73 |
| Shewanella oneidensis MR-1 | 0.31 | SO3817 | panE | 2-dehydropantoate 2-reductase (NCBI ptt file) | 0.56 | SO3352 | | conserved hypothetical protein TIGR00044 (NCBI ptt file) | low | > 76 |
| Shewanella loihica PV-4 | 0.31 | Shew_2895 | | 2-dehydropantoate 2-reductase (RefSeq) | 0.55 | Shew_1137 | | alanine racemase domain-containing protein (RefSeq) | low | > 60 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.30 | GFF4336 | | 2-dehydropantoate 2-reductase (EC 1.1.1.169) | 0.58 | GFF3054 | | Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC | low | > 78 |
| Alteromonas macleodii MIT1002 | 0.28 | MIT1002_01217 | | 2-dehydropantoate 2-reductase | 0.49 | MIT1002_03061 | | pyridoxal phosphate enzyme, YggS family | low | > 70 |
| Pseudomonas sp. SVBP6 | 0.27 | COO64_RS11970 | | putative 2-dehydropantoate 2-reductase | 0.47 | COO64_RS13000 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 93 |
| Pseudomonas stutzeri RCH2 | 0.27 | Psest_1140 | | 2-dehydropantoate 2-reductase | 0.49 | Psest_0284 | | pyridoxal phosphate enzyme, YggS family | low | > 67 |
| Shewanella amazonensis SB2B | 0.27 | Sama_2559 | | 2-dehydropantoate 2-reductase (RefSeq) | 0.48 | Sama_2477 | | hypothetical protein (RefSeq) | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.25 | Psyr_4088 | | ketopantoate reductase | 0.49 | Psyr_0477 | | Protein of unknown function UPF0001 | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.25 | Psyr_4088 | | ketopantoate reductase | 0.49 | Psyr_0477 | | Protein of unknown function UPF0001 | low | > 86 |
| Pseudomonas aeruginosa PUPa3 | 0.25 | DQ20_RS56950 | | putative 2-dehydropantoate 2-reductase | 0.48 | DQ20_RS37350 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 101 |
| Pseudomonas aeruginosa MRSN321 | 0.24 | DY961_RS24500 | | putative 2-dehydropantoate 2-reductase | 0.48 | DY961_RS21950 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 100 |
| Pseudomonas aeruginosa PA14 | 0.24 | IKLFDK_02110 | | putative 2-dehydropantoate 2-reductase | 0.47 | IKLFDK_23450 | | Pyridoxal phosphate homeostasis protein | low | > 98 |
| Pseudomonas sp. RS175 | 0.24 | PFR28_03426 | | 2-dehydropantoate 2-reductase | 0.49 | PFR28_04242 | | Pyridoxal phosphate homeostasis protein | low | > 88 |
| Marinobacter adhaerens HP15 | 0.24 | HP15_1312 | | 2-dehydropantoate 2-reductase | 0.42 | HP15_288 | | alanine racemase domain protein | low | > 73 |
| Pseudomonas fluorescens FW300-N2C3 | 0.24 | AO356_17955 | | 2-dehydropantoate 2-reductase | 0.51 | AO356_13425 | | hypothetical protein | low | > 104 |
| Pseudomonas fluorescens FW300-N2E2 | 0.24 | Pf6N2E2_5521 | | 2-dehydropantoate 2-reductase (EC 1.1.1.169) | 0.49 | Pf6N2E2_4601 | | Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC | low | > 103 |
| Pseudomonas putida KT2440 | 0.24 | PP_1351 | | putative 2-dehydropantoate 2-reductase | 0.49 | PP_5094 | | putative enzyme with PLP binding domain | low | > 96 |
| Pseudomonas segetis P6 | 0.23 | MPMX49_03786 | | 2-dehydropantoate 2-reductase | 0.50 | MPMX49_00611 | | Pyridoxal phosphate homeostasis protein | low | > 75 |
| Pseudomonas sp. BP01 | 0.23 | JOY50_RS15040 | | putative 2-dehydropantoate 2-reductase | 0.50 | JOY50_RS20910 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 84 |
| Pseudomonas fluorescens FW300-N2E3 | 0.23 | AO353_03645 | | 2-dehydropantoate 2-reductase | 0.47 | AO353_08160 | | hypothetical protein | low | > 101 |
| Pseudomonas sp. S08-1 | 0.23 | OH686_08220 | | 2-dehydropantoate 2-reductase | 0.50 | OH686_10975 | | Pyridoxal phosphate-containing protein YggS | low | > 80 |
| Pseudomonas orientalis W4I3 | 0.22 | QF045_RS24680 | | putative 2-dehydropantoate 2-reductase | 0.50 | QF045_RS01125 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 93 |
| Pseudomonas fluorescens GW456-L13 | 0.22 | PfGW456L13_1839 | | 2-dehydropantoate 2-reductase (EC 1.1.1.169) | 0.52 | PfGW456L13_1011 | | Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC | low | > 87 |
| Pseudomonas fluorescens FW300-N1B4 | 0.22 | Pf1N1B4_651 | | 2-dehydropantoate 2-reductase (EC 1.1.1.169) | 0.51 | Pf1N1B4_2342 | | Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC | — | — |
| Pseudomonas sp. DMC3 | 0.22 | GFF5199 | | 2-dehydropantoate 2-reductase | 0.52 | GFF209 | | Pyridoxal phosphate homeostasis protein | low | > 89 |
| Pseudomonas simiae WCS417 | 0.22 | PS417_22515 | | 2-dehydropantoate 2-reductase | 0.50 | PS417_26725 | | hypothetical protein | low | > 88 |
| Pseudomonas fluorescens SBW25 | 0.21 | PFLU_RS24155 | | putative 2-dehydropantoate 2-reductase | 0.49 | PFLU_RS28370 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.21 | PFLU_RS24155 | | putative 2-dehydropantoate 2-reductase | 0.49 | PFLU_RS28370 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 109 |
| Rhodopseudomonas palustris CGA009 | 0.21 | TX73_023700 | | 2-dehydropantoate 2-reductase | 0.31 | TX73_014475 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 86 |
| Pseudomonas lactucae CFBP13502 | 0.21 | GEMAOFIL_04655 | | 2-dehydropantoate 2-reductase | 0.50 | GEMAOFIL_05482 | | Pyridoxal phosphate homeostasis protein | low | > 96 |
| Bosea sp. OAE506 | 0.20 | ABIE41_RS11280 | | 2-dehydropantoate 2-reductase | 0.29 | ABIE41_RS04720 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 77 |
| Herbaspirillum seropedicae SmR1 | 0.20 | HSERO_RS09230 | | 2-dehydropantoate 2-reductase | 0.53 | HSERO_RS18995 | | hypothetical protein | low | > 78 |
| Paraburkholderia sabiae LMG 24235 | 0.19 | QEN71_RS38425 | | ketopantoate reductase family protein | 0.49 | QEN71_RS26595 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 153 |
| Variovorax sp. SCN45 | 0.19 | GFF3590 | | 2-dehydropantoate 2-reductase (EC 1.1.1.169) | 0.50 | GFF3744 | | Pyridoxal phosphate-containing protein YggS | — | — |
| Variovorax sp. OAS795 | 0.18 | ABID97_RS00870 | | 2-dehydropantoate 2-reductase | 0.50 | ABID97_RS00250 | | YggS family pyridoxal phosphate-dependent enzyme | — | — |
| Acidovorax sp. GW101-3H11 | 0.18 | Ac3H11_2346 | | 2-dehydropantoate 2-reductase (EC 1.1.1.169) | 0.50 | Ac3H11_4474 | | Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC | low | > 79 |
| Ralstonia sp. UNC404CL21Col | 0.16 | ABZR87_RS15450 | | 2-dehydropantoate 2-reductase | 0.46 | ABZR87_RS01225 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 80 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.15 | H281DRAFT_01683 | | ketopantoate reductase (EC 1.1.1.169) | 0.49 | H281DRAFT_04680 | | hypothetical protein | low | > 103 |
| Cupriavidus basilensis FW507-4G11 | 0.14 | RR42_RS32960 | | 2-dehydropantoate 2-reductase | 0.50 | RR42_RS17355 | | hypothetical protein | low | > 128 |
| Burkholderia phytofirmans PsJN | 0.14 | BPHYT_RS27355 | | 2-dehydropantoate 2-reductase | 0.51 | BPHYT_RS03495 | | hypothetical protein | low | > 109 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.11 | CA264_06150 | | hypothetical protein | 0.26 | CA264_06410 | | YggS family pyridoxal phosphate enzyme | low | > 74 |
| Paraburkholderia graminis OAS925 | 0.11 | ABIE53_006287 | | 2-dehydropantoate 2-reductase | 0.50 | ABIE53_000841 | | pyridoxal phosphate enzyme (YggS family) | low | > 113 |
| Caulobacter crescentus NA1000 | 0.10 | CCNA_00262 | | ketopantoate reductase panE/ApbA family protein | 0.26 | CCNA_03861 | | pyridoxal 5'-phosphate dependent enzyme class III | low | > 66 |
| Caulobacter crescentus NA1000 Δfur | 0.10 | CCNA_00262 | | ketopantoate reductase panE/ApbA family protein | 0.26 | CCNA_03861 | | pyridoxal 5'-phosphate dependent enzyme class III | low | > 67 |
| Magnetospirillum magneticum AMB-1 | 0.09 | AMB_RS10015 | | 2-dehydropantoate 2-reductase | 0.30 | AMB_RS00120 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 64 |
| Azospirillum brasilense Sp245 | 0.09 | AZOBR_RS12955 | | 2-dehydropantoate 2-reductase | 0.32 | AZOBR_RS01870 | | alanine racemase | — | — |
| Rhodospirillum rubrum S1H | 0.09 | Rru_A3518 | | 2-dehydropantoate 2-reductase (NCBI) | 0.30 | Rru_A1141 | | Protein of unknown function UPF0001 (NCBI) | low | > 58 |
| Ralstonia solanacearum GMI1000 | 0.09 | RS_RS00860 | | 2-dehydropantoate 2-reductase | 0.45 | RS_RS13435 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 80 |
| Rhodanobacter sp. FW510-T8 | 0.09 | OKGIIK_09940 | panE | 2-dehydropantoate 2-reductase | 0.25 | OKGIIK_09885 | | Pyridoxal phosphate homeostasis protein | low | > 53 |
| Rhodanobacter denitrificans FW104-10B01 | 0.09 | LRK54_RS03070 | | 2-dehydropantoate 2-reductase | 0.27 | LRK54_RS02905 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 59 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.09 | GFF1821 | | 2-dehydropantoate 2-reductase (EC 1.1.1.169) | 0.49 | GFF2722 | | Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC | low | > 90 |
| Rhodanobacter denitrificans MT42 | 0.09 | LRK55_RS02820 | | 2-dehydropantoate 2-reductase | 0.27 | LRK55_RS02655 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 63 |
| Ralstonia solanacearum UW163 | 0.08 | UW163_RS03340 | | 2-dehydropantoate 2-reductase | 0.44 | UW163_RS08050 | | YggS family pyridoxal phosphate-dependent enzyme | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.08 | RALBFv3_RS10240 | | 2-dehydropantoate 2-reductase | 0.44 | RALBFv3_RS05575 | | YggS family pyridoxal phosphate-dependent enzyme | low | > 76 |
Not shown: 2 genomes with orthologs for CSW01_11730 only; 38 genomes with orthologs for CSW01_02455 only