Conservation of cofitness between CSW01_00335 and CSW01_00245 in Vibrio cholerae E7946 ATCC 55056

79 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_00335 phosphomethylpyrimidine synthase 1.0 CSW01_00245 DNA-protecting protein DprA 0.48 14
Pectobacterium carotovorum WPP14 0.76 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.39 HER17_RS02230 DNA-protecting protein DprA low > 75
Rahnella sp. WP5 0.76 EX31_RS16815 phosphomethylpyrimidine synthase ThiC 0.36 EX31_RS15970 DNA-protecting protein DprA low > 89
Klebsiella pneumoniae MKP103 0.75 KDGMDA_10040 phosphomethylpyrimidine synthase ThiC 0.35 KDGMDA_06535 DNA-protecting protein DprA low > 95
Dickeya dianthicola ME23 0.75 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.37 DZA65_RS20335 DNA-protecting protein DprA low > 75
Erwinia amylovora T8 0.75 OLJFJH_06740 phosphomethylpyrimidine synthase ThiC 0.35 OLJFJH_03705 DNA-protecting protein DprA low > 58
Dickeya dadantii 3937 0.75 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.37 DDA3937_RS19120 DNA-protecting protein DprA low > 74
Erwinia tracheiphila SCR3 0.75 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC 0.37 LU632_RS22465 dprA DNA-protecting protein DprA low > 73
Erwinia tracheiphila HP pepo 2.2 0.75 IJEDHG_10885 thiC phosphomethylpyrimidine synthase ThiC 0.38 IJEDHG_12485 dprA DNA-protecting protein DprA low > 61
Pantoea sp. MT58 0.75 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.37 IAI47_02295 DNA-protecting protein DprA low > 76
Escherichia coli ECOR27 0.75 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 0.36 NOLOHH_09335 dprA DNA-protecting protein DprA low > 76
Serratia liquefaciens MT49 0.75 IAI46_01320 phosphomethylpyrimidine synthase ThiC 0.36 IAI46_23260 DNA-protecting protein DprA low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.75 GFF4198 Thiamin biosynthesis protein ThiC 0.37 GFF2393 Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake low > 78
Enterobacter sp. TBS_079 0.75 MPMX20_00217 Phosphomethylpyrimidine synthase 0.35 MPMX20_04193 hypothetical protein low > 85
Escherichia coli HS(pFamp)R (ATCC 700891) 0.74 OHPLBJKB_04056 Phosphomethylpyrimidine synthase 0.36 OHPLBJKB_00418 hypothetical protein low > 74
Escherichia coli BW25113 0.74 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.36 b4473 smf hypothetical protein (NCBI) low > 76
Escherichia coli ECRC62 0.74 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.35 BNILDI_02185 dprA DNA-protecting protein DprA low > 75
Pantoea agglomerans CFBP13505 P0401 0.74 PagCFBP13505_RS22620 phosphomethylpyrimidine synthase ThiC 0.36 PagCFBP13505_RS22540 DNA-protecting protein DprA low > 74
Klebsiella michiganensis M5al 0.74 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.34 BWI76_RS25665 DNA-processing protein DprA low > 92
Escherichia coli BL21 0.74 ECD_03871 phosphomethylpyrimidine synthase 0.36 ECD_03136 DNA recombination-mediator A family protein low > 61
Escherichia coli ECRC102 0.74 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC 0.36 NIAGMN_15305 dprA DNA-protecting protein DprA low > 80
Escherichia coli ECRC101 0.74 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.36 MCAODC_08065 dprA DNA-protecting protein DprA low > 87
Escherichia coli ECRC98 0.74 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC 0.36 JDDGAC_21165 dprA DNA-protecting protein DprA low > 87
Escherichia coli Nissle 1917 0.74 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.36 ECOLIN_RS18860 DNA-protecting protein DprA low > 55
Escherichia coli ECRC99 0.74 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC 0.36 KEDOAH_10605 dprA DNA-protecting protein DprA — —
Dickeya dianthicola 67-19 0.74 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.37 HGI48_RS19210 DNA-protecting protein DprA low > 71
Escherichia fergusonii Becca 0.74 EFB2_04617 Phosphomethylpyrimidine synthase 0.36 EFB2_00538 hypothetical protein low > 86
Escherichia coli ECOR38 0.74 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.36 HEPCGN_16365 dprA DNA-protecting protein DprA low > 88
Enterobacter asburiae PDN3 0.74 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.36 EX28DRAFT_0042 DNA protecting protein DprA low > 76
Shewanella loihica PV-4 0.74 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.34 Shew_3734 DNA protecting protein DprA (RefSeq) low > 60
Alteromonas macleodii MIT1002 0.74 MIT1002_00097 Phosphomethylpyrimidine synthase 0.32 MIT1002_00022 DNA protecting protein DprA low > 70
Shewanella amazonensis SB2B 0.72 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.37 Sama_0045 DNA processing protein DprA, putative (RefSeq) low > 62
Shewanella oneidensis MR-1 0.71 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.36 SO0034 DNA processing protein DprA, putative (NCBI ptt file) low > 76
Pseudomonas aeruginosa PUPa3 0.71 DQ20_RS51400 thiC;go_function=iron-sulfur phosphomethylpyrimidine synthase ThiC 0.31 DQ20_RS58710 dprA;go_process=DNA-mediated DNA-processing protein DprA low > 101
Pseudomonas aeruginosa MRSN321 0.71 DY961_RS10660 thiC;go_function=iron-sulfur phosphomethylpyrimidine synthase ThiC 0.31 DY961_RS26305 dprA;go_process=DNA-mediated DNA-processing protein DprA low > 100
Pseudomonas aeruginosa PA14 0.71 IKLFDK_28675 phosphomethylpyrimidine synthase ThiC 0.31 IKLFDK_25455 DNA-processing protein DprA low > 98
Shewanella sp. ANA-3 0.71 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.35 Shewana3_0037 DNA protecting protein DprA (RefSeq) low > 73
Pseudomonas sp. S08-1 0.70 OH686_15885 phosphomethylpyrimidine synthase 0.31 OH686_12505 DNA protecting protein DprA low > 80
Pseudomonas sp. DMC3 0.70 GFF3183 Phosphomethylpyrimidine synthase 0.28 GFF594 hypothetical protein low > 89
Marinobacter adhaerens HP15 0.70 HP15_453 thiamine biosynthesis protein thiC 0.29 HP15_3746 DNA protecting protein DprA low > 73
Pseudomonas stutzeri RCH2 0.69 Psest_0477 thiamine biosynthesis protein ThiC 0.31 Psest_0025 DNA protecting protein DprA low > 67
Pseudomonas fluorescens FW300-N2C3 0.69 AO356_08810 thiamine biosynthesis protein ThiC 0.29 AO356_11295 DNA processing protein DprA low > 104
Pseudomonas fluorescens GW456-L13 0.69 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.29 PfGW456L13_648 Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake low > 87
Dechlorosoma suillum PS 0.69 Dsui_0422 thiamine biosynthesis protein ThiC 0.31 Dsui_0819 DNA protecting protein DprA — —
Pseudomonas fluorescens FW300-N1B4 0.69 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.28 Pf1N1B4_1910 Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake low > 87
Methylophilus sp. DMC18 0.69 GFF2191 Phosphomethylpyrimidine synthase 0.30 GFF1494 hypothetical protein low > 43
Pseudomonas fluorescens FW300-N2E3 0.69 AO353_13010 thiamine biosynthesis protein ThiC 0.29 AO353_10650 DNA processing protein DprA low > 101
Acinetobacter radioresistens SK82 0.68 MPMX26_00180 Phosphomethylpyrimidine synthase 0.30 MPMX26_00114 hypothetical protein low > 36
Acinetobacter baumannii LAC-4 0.68 RR41_RS17715 phosphomethylpyrimidine synthase ThiC 0.29 RR41_RS18085 DNA-processing protein DprA low > 55
Pontibacter actiniarum KMM 6156, DSM 19842 0.68 CA264_20435 phosphomethylpyrimidine synthase ThiC 0.21 CA264_06145 DNA protecting protein DprA low > 74
Lysobacter sp. OAE881 0.68 ABIE51_RS17515 phosphomethylpyrimidine synthase ThiC 0.25 ABIE51_RS02235 DNA-processing protein DprA low > 62
Castellaniella sp019104865 MT123 0.68 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC 0.31 ABCV34_RS14195 DNA-processing protein DprA low > 48
Herbaspirillum seropedicae SmR1 0.68 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC 0.26 HSERO_RS23400 DNA processing protein DprA low > 78
Paraburkholderia bryophila 376MFSha3.1 0.68 H281DRAFT_00395 hydroxymethylpyrimidine synthase 0.28 H281DRAFT_02242 DNA protecting protein DprA low > 103
Paraburkholderia graminis OAS925 0.68 ABIE53_002857 phosphomethylpyrimidine synthase 0.28 ABIE53_000387 DNA processing protein low > 113
Dyella japonica UNC79MFTsu3.2 0.67 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC 0.29 ABZR86_RS13870 DNA-processing protein DprA low > 74
Burkholderia phytofirmans PsJN 0.67 BPHYT_RS13220 phosphomethylpyrimidine synthase 0.30 BPHYT_RS01450 DNA-binding protein low > 109
Paraburkholderia sabiae LMG 24235 0.67 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC 0.29 QEN71_RS00150 DNA-processing protein DprA low > 153
Xanthomonas campestris pv. campestris strain 8004 0.66 Xcc-8004.1066.1 hypothetical protein 0.29 Xcc-8004.4746.1 Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake low > 74
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC 0.27 ABZR87_RS04985 DNA-processing protein DprA low > 80
Ralstonia solanacearum UW163 0.65 UW163_RS03640 phosphomethylpyrimidine synthase ThiC 0.28 UW163_RS03825 DNA-protecting protein DprA — —
Ralstonia solanacearum GMI1000 0.65 RS_RS00555 phosphomethylpyrimidine synthase 0.28 RS_RS00340 DNA-protecting protein DprA low > 80
Cupriavidus basilensis FW507-4G11 0.65 RR42_RS01290 thiamine biosynthesis protein ThiC 0.33 RR42_RS20480 DNA processing protein DprA low > 128
Ralstonia solanacearum IBSBF1503 0.65 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC 0.28 RALBFv3_RS09755 DNA-protecting protein DprA low > 76
Ralstonia solanacearum PSI07 0.65 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC 0.26 RPSI07_RS23610 DNA-protecting protein DprA low > 81
Kangiella aquimarina DSM 16071 0.65 B158DRAFT_0295 hydroxymethylpyrimidine synthase 0.33 B158DRAFT_0400 DNA protecting protein DprA low > 40
Variovorax sp. SCN45 0.64 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.27 GFF5489 Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake low > 127
Variovorax sp. OAS795 0.63 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC 0.31 ABID97_RS01830 DNA-processing protein DprA low > 91
Hydrogenophaga sp. GW460-11-11-14-LB1 0.63 GFF4626 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.33 GFF2571 Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake low > 90
Magnetospirillum magneticum AMB-1 0.62 AMB_RS01125 phosphomethylpyrimidine synthase 0.27 AMB_RS03500 DNA-protecting protein DprA — —
Agrobacterium fabrum C58 0.61 Atu2569 thiamine biosynthesis protein 0.25 Atu1305 DNA processing chain A low > 89
Dinoroseobacter shibae DFL-12 0.61 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) 0.24 Dshi_1138 DNA protecting protein DprA (RefSeq) — —
Phaeobacter inhibens DSM 17395 0.61 PGA1_c09110 thiamine biosynthesis protein ThiC 0.22 PGA1_c06230 putative protein Smf low > 62
Acidovorax sp. GW101-3H11 0.61 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.29 Ac3H11_4411 Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake low > 79
Azospirillum brasilense Sp245 0.61 AZOBR_RS07940 phosphomethylpyrimidine synthase 0.28 AZOBR_RS15885 DNA processing protein DprA low > 97
Azospirillum sp. SherDot2 0.59 MPMX19_00336 Phosphomethylpyrimidine synthase 0.28 MPMX19_01508 hypothetical protein low > 112
Phocaeicola vulgatus CL09T03C04 0.55 HMPREF1058_RS03280 phosphomethylpyrimidine synthase ThiC 0.21 HMPREF1058_RS11685 DNA-protecting protein DprA low > 67
Phocaeicola dorei CL03T12C01 0.55 ABI39_RS17760 phosphomethylpyrimidine synthase ThiC 0.21 ABI39_RS05220 DNA-processing protein DprA low > 72
Bacteroides thetaiotaomicron VPI-5482 0.55 BT0650 thiamine biosynthesis protein ThiC (NCBI ptt file) 0.20 BT3070 Smf protein DNA processing chain A (NCBI ptt file) low > 81
Bacteroides ovatus ATCC 8483 0.55 BACOVA_02358 thiamine biosynthesis protein ThiC 0.22 BACOVA_02721 DNA protecting protein DprA low > 96

Not shown: 32 genomes with orthologs for CSW01_00335 only; 3 genomes with orthologs for CSW01_00245 only