Conservation of cofitness between BWI76_RS26685 and BWI76_RS05440 in Klebsiella michiganensis M5al

77 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS26685 glutathione-disulfide reductase 1.0 BWI76_RS05440 hydroxyacylglutathione hydrolase 0.49 12
Enterobacter asburiae PDN3 0.92 EX28DRAFT_4061 NADPH-glutathione reductase (EC 1.8.1.7) 0.79 EX28DRAFT_2682 hydroxyacylglutathione hydrolase 0.68 16
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.91 GFF513 Glutathione reductase (EC 1.8.1.7) 0.75 GFF4044 Hydroxyacylglutathione hydrolase (EC 3.1.2.6) low > 78
Escherichia fergusonii Becca 0.91 EFB2_00315 Glutathione reductase 0.75 EFB2_03831 Hydroxyacylglutathione hydrolase GloB low > 86
Enterobacter sp. TBS_079 0.91 MPMX20_04399 Glutathione reductase 0.78 MPMX20_00897 Hydroxyacylglutathione hydrolase GloB low > 85
Escherichia coli Nissle 1917 0.91 ECOLIN_RS19995 glutathione-disulfide reductase 0.74 ECOLIN_RS01160 hydroxyacylglutathione hydrolase low > 55
Escherichia coli ECRC100 0.91 OKFHMN_16405 gorA glutathione-disulfide reductase 0.75 OKFHMN_09980 gloB hydroxyacylglutathione hydrolase low > 80
Escherichia coli ECOR38 0.91 HEPCGN_15315 gorA glutathione-disulfide reductase 0.75 HEPCGN_07920 gloB hydroxyacylglutathione hydrolase low > 87
Escherichia coli ECRC99 0.91 KEDOAH_11740 gorA glutathione-disulfide reductase 0.75 KEDOAH_18175 gloB hydroxyacylglutathione hydrolase — —
Escherichia coli ECRC102 0.91 NIAGMN_14170 gorA glutathione-disulfide reductase 0.75 NIAGMN_07830 gloB hydroxyacylglutathione hydrolase — —
Escherichia coli ECRC98 0.91 JDDGAC_20035 gorA glutathione-disulfide reductase 0.75 JDDGAC_13575 gloB hydroxyacylglutathione hydrolase low > 86
Escherichia coli ECRC101 0.91 MCAODC_06920 gorA glutathione-disulfide reductase 0.75 MCAODC_00495 gloB hydroxyacylglutathione hydrolase low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.91 OHPLBJKB_00203 Glutathione reductase 0.75 OHPLBJKB_03449 Hydroxyacylglutathione hydrolase GloB low > 73
Escherichia coli ECRC62 0.91 BNILDI_03220 gorA glutathione-disulfide reductase 0.75 BNILDI_09345 gloB hydroxyacylglutathione hydrolase low > 75
Escherichia coli ECOR27 0.91 NOLOHH_08340 gorA glutathione-disulfide reductase 0.75 NOLOHH_02325 gloB hydroxyacylglutathione hydrolase low > 75
Escherichia coli BL21 0.91 ECD_03349 glutathione oxidoreductase 0.75 ECD_00205 hydroxyacylglutathione hydrolase low > 61
Escherichia coli BW25113 0.91 b3500 gor glutathione reductase (NCBI) 0.75 b0212 gloB predicted hydroxyacylglutathione hydrolase (NCBI) low > 76
Pectobacterium carotovorum WPP14 0.88 HER17_RS21240 glutathione-disulfide reductase 0.59 HER17_RS05455 hydroxyacylglutathione hydrolase low > 75
Pantoea sp. MT58 0.86 IAI47_01325 glutathione-disulfide reductase 0.63 IAI47_15340 hydroxyacylglutathione hydrolase low > 76
Serratia liquefaciens MT49 0.86 IAI46_24240 glutathione-disulfide reductase 0.58 IAI46_04135 hydroxyacylglutathione hydrolase low > 86
Dickeya dianthicola ME23 0.85 DZA65_RS00055 glutathione-disulfide reductase 0.56 DZA65_RS17265 hydroxyacylglutathione hydrolase low > 75
Erwinia tracheiphila SCR3 0.85 LU632_RS19495 gorA glutathione-disulfide reductase 0.62 LU632_RS01080 gloB hydroxyacylglutathione hydrolase low > 74
Dickeya dadantii 3937 0.85 DDA3937_RS21245 glutathione-disulfide reductase 0.59 DDA3937_RS16060 hydroxyacylglutathione hydrolase low > 74
Dickeya dianthicola 67-19 0.85 HGI48_RS00065 glutathione-disulfide reductase 0.56 HGI48_RS16180 hydroxyacylglutathione hydrolase low > 71
Rahnella sp. WP5 0.85 EX31_RS05175 glutathione-disulfide reductase 0.57 EX31_RS21200 hydroxyacylglutathione hydrolase low > 89
Vibrio cholerae E7946 ATCC 55056 0.75 CSW01_01000 glutathione-disulfide reductase 0.46 CSW01_11395 hydroxyacylglutathione hydrolase low > 62
Shewanella sp. ANA-3 0.71 Shewana3_4054 glutathione reductase (RefSeq) 0.37 Shewana3_2369 beta-lactamase domain-containing protein (RefSeq) low > 73
Shewanella oneidensis MR-1 0.71 SO4702 gor glutathione reductase (NCBI ptt file) 0.35 SO2563 metallo-beta-lactamase family protein (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.71 Shew_3660 glutathione reductase (RefSeq) 0.36 Shew_2114 hydroxyacylglutathione hydrolase (RefSeq) low > 60
Shewanella amazonensis SB2B 0.71 Sama_3543 glutathione reductase (RefSeq) 0.40 Sama_1884 hydroxyacylglutathione hydrolase (RefSeq) low > 62
Alteromonas macleodii MIT1002 0.66 MIT1002_03638 Glutathione reductase 0.41 MIT1002_02494 Hydroxyacylglutathione hydrolase low > 70
Kangiella aquimarina DSM 16071 0.60 B158DRAFT_0460 NADPH-glutathione reductase (EC 1.8.1.7) 0.35 B158DRAFT_1061 hydroxyacylglutathione hydrolase low > 40
Dyella japonica UNC79MFTsu3.2 0.46 ABZR86_RS08925 glutathione-disulfide reductase 0.43 ABZR86_RS07285 hydroxyacylglutathione hydrolase low > 74
Xanthomonas campestris pv. campestris strain 8004 0.41 Xcc-8004.1917.1 Glutathione reductase (EC 1.8.1.7) 0.42 Xcc-8004.4036.1 Hydroxyacylglutathione hydrolase (EC 3.1.2.6) low > 74
Pseudomonas putida KT2440 0.41 PP_3819 glutathione reductase (NADPH) 0.41 PP_4144 Hydroxyacylglutathione hydrolase low > 96
Pseudomonas sp. S08-1 0.41 OH686_01610 glutathione-disulfide reductase 0.40 OH686_03580 hydroxyacylglutathione hydrolase low > 80
Pseudomonas fluorescens FW300-N2E3 0.40 AO353_24480 glutathione reductase 0.41 AO353_23490 hydroxyacylglutathione hydrolase low > 101
Pseudomonas fluorescens GW456-L13 0.40 PfGW456L13_2924 Glutathione reductase (EC 1.8.1.7) 0.38 PfGW456L13_3340 Hydroxyacylglutathione hydrolase (EC 3.1.2.6) low > 87
Pseudomonas fluorescens SBW25 0.40 PFLU_RS14555 glutathione-disulfide reductase 0.40 PFLU_RS12910 hydroxyacylglutathione hydrolase low > 109
Pseudomonas fluorescens SBW25-INTG 0.40 PFLU_RS14555 glutathione-disulfide reductase 0.40 PFLU_RS12910 hydroxyacylglutathione hydrolase low > 109
Pseudomonas fluorescens FW300-N1B4 0.40 Pf1N1B4_5014 Glutathione reductase (EC 1.8.1.7) 0.40 Pf1N1B4_4596 Hydroxyacylglutathione hydrolase (EC 3.1.2.6) low > 87
Pseudomonas fluorescens FW300-N2C3 0.40 AO356_22800 glutathione reductase 0.38 AO356_24480 hydroxyacylglutathione hydrolase low > 104
Pseudomonas simiae WCS417 0.40 PS417_14060 glutathione reductase 0.40 PS417_12220 hydroxyacylglutathione hydrolase — —
Lysobacter sp. OAE881 0.40 ABIE51_RS06410 glutathione-disulfide reductase 0.43 ABIE51_RS14105 hydroxyacylglutathione hydrolase low > 62
Pseudomonas sp. RS175 0.40 PFR28_02483 Glutathione reductase 0.38 PFR28_01552 Hydroxyacylglutathione hydrolase GloB low > 88
Pseudomonas fluorescens FW300-N2E2 0.39 Pf6N2E2_446 Glutathione reductase (EC 1.8.1.7) 0.39 Pf6N2E2_587 Hydroxyacylglutathione hydrolase (EC 3.1.2.6) low > 103
Azospirillum sp. SherDot2 0.39 MPMX19_04368 Glutathione amide reductase 0.39 MPMX19_06029 Hydroxyacylglutathione hydrolase GloB low > 112
Azospirillum brasilense Sp245 0.39 AZOBR_RS09745 glutathione reductase 0.34 AZOBR_RS20450 hydroxyacylglutathione hydrolase low > 97
Pseudomonas stutzeri RCH2 0.38 Psest_2230 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes 0.38 Psest_2071 hydroxyacylglutathione hydrolase low > 67
Herbaspirillum seropedicae SmR1 0.38 HSERO_RS16580 glutathione reductase 0.39 HSERO_RS17120 hydroxyacylglutathione hydrolase low > 78
Magnetospirillum magneticum AMB-1 0.38 AMB_RS08430 glutathione-disulfide reductase 0.31 AMB_RS21210 hydroxyacylglutathione hydrolase low > 64
Variovorax sp. SCN45 0.38 GFF3591 Glutathione reductase (EC 1.8.1.7) 0.40 GFF1118 Hydroxyacylglutathione hydrolase (EC 3.1.2.6) low > 127
Pseudomonas syringae pv. syringae B728a 0.37 Psyr_2979 NADPH-glutathione reductase 0.41 Psyr_1761 Hydroxyacylglutathione hydrolase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.37 Psyr_2979 NADPH-glutathione reductase 0.41 Psyr_1761 Hydroxyacylglutathione hydrolase low > 86
Synechococcus elongatus PCC 7942 0.37 Synpcc7942_0842 gor glutathione reductase 0.38 Synpcc7942_1403 Hydroxyacylglutathione hydrolase low > 38
Variovorax sp. OAS795 0.36 ABID97_RS00865 glutathione-disulfide reductase 0.42 ABID97_RS14730 hydroxyacylglutathione hydrolase low > 91
Rhodospirillum rubrum S1H 0.36 Rru_A0682 Glutathione reductase (NCBI) 0.35 Rru_A3270 Hydroxyacylglutathione hydrolase (NCBI) — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.36 GFF372 Glutathione reductase (EC 1.8.1.7) 0.42 GFF4257 Hydroxyacylglutathione hydrolase (EC 3.1.2.6) low > 90
Sphingomonas koreensis DSMZ 15582 0.36 Ga0059261_1951 NADPH-glutathione reductase (EC 1.8.1.7) 0.31 Ga0059261_2759 hydroxyacylglutathione hydrolase low > 68
Marinobacter adhaerens HP15 0.35 HP15_1612 protein containing FAD-dependent pyridine nucleotide-disulfide oxidoreductase / Pyridine nucleotide-disulfide oxidoreductase, dimerization 0.42 HP15_1805 hydroxyacylglutathione hydrolase low > 73
Caulobacter crescentus NA1000 0.34 CCNA_02387 glutathione reductase 0.28 CCNA_00553 hydroxyacylglutathione hydrolase low > 66
Caulobacter crescentus NA1000 Δfur 0.34 CCNA_02387 glutathione reductase 0.28 CCNA_00553 hydroxyacylglutathione hydrolase low > 67
Phaeobacter inhibens DSM 17395 0.33 PGA1_c23720 glutathione reductase Gor 0.34 PGA1_c25140 hydroxyacylglutathione hydrolase GloB low > 62
Rhodopseudomonas palustris CGA009 0.33 TX73_010220 glutathione-disulfide reductase 0.30 TX73_003155 hydroxyacylglutathione hydrolase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.32 A4249_RS06570 glutathione-disulfide reductase 0.28 A4249_RS00300 hydroxyacylglutathione hydrolase low > 48
Dinoroseobacter shibae DFL-12 0.32 Dshi_2737 pyridine nucleotide-disulphide oxidoreductase dimerisation region (RefSeq) 0.30 Dshi_2691 Hydroxyacylglutathione hydrolase (RefSeq) low > 64
Rhizobium sp. OAE497 0.32 ABIE40_RS10515 glutathione-disulfide reductase 0.28 ABIE40_RS17605 hydroxyacylglutathione hydrolase low > 107
Agrobacterium fabrum C58 0.31 Atu1611 glutathione reductase 0.30 Atu3614 glyoxalase II — —
Sinorhizobium meliloti 1021 0.31 SMc00154 glutathione reductase 0.31 SMc00708 hydroxyacylglutathione hydrolase (glyoxalase II) (GLX II) protein — —
Bosea sp. OAE506 0.30 ABIE41_RS20940 glutathione-disulfide reductase 0.21 ABIE41_RS06025 hydroxyacylglutathione hydrolase low > 77
Cupriavidus basilensis FW507-4G11 0.25 RR42_RS20585 pyridine nucleotide-disulfide oxidoreductase 0.35 RR42_RS13570 hydroxyacylglutathione hydrolase low > 128
Ralstonia solanacearum PSI07 0.23 RPSI07_RS23885 NAD(P)/FAD-dependent oxidoreductase 0.34 RPSI07_RS15230 hydroxyacylglutathione hydrolase low > 81
Rhodanobacter denitrificans MT42 0.22 LRK55_RS17305 NAD(P)/FAD-dependent oxidoreductase 0.42 LRK55_RS16490 hydroxyacylglutathione hydrolase low > 63
Rhodanobacter denitrificans FW104-10B01 0.22 LRK54_RS09620 NAD(P)/FAD-dependent oxidoreductase 0.42 LRK54_RS16765 hydroxyacylglutathione hydrolase low > 59
Ralstonia solanacearum GMI1000 0.22 RS_RS00065 NAD(P)/FAD-dependent oxidoreductase 0.34 RS_RS07605 hydroxyacylglutathione hydrolase low > 80
Rhodanobacter sp. FW510-T8 0.21 OKGIIK_14635 lpd NAD(P)/FAD-dependent oxidoreductase 0.41 OKGIIK_08000 gloB hydroxyacylglutathione hydrolase low > 52
Ralstonia solanacearum UW163 0.21 UW163_RS04115 NAD(P)/FAD-dependent oxidoreductase 0.33 UW163_RS15525 hydroxyacylglutathione hydrolase — —
Ralstonia solanacearum IBSBF1503 0.21 RALBFv3_RS09465 NAD(P)/FAD-dependent oxidoreductase 0.33 RALBFv3_RS02215 hydroxyacylglutathione hydrolase low > 76

Not shown: 1 genomes with orthologs for BWI76_RS26685 only; 9 genomes with orthologs for BWI76_RS05440 only