Conservation of cofitness between BPHYT_RS13220 and BPHYT_RS33835 in Burkholderia phytofirmans PsJN

77 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Burkholderia phytofirmans PsJN 1.0 BPHYT_RS13220 phosphomethylpyrimidine synthase 1.0 BPHYT_RS33835 O-succinylhomoserine sulfhydrylase 0.70 11
Paraburkholderia graminis OAS925 0.99 ABIE53_002857 phosphomethylpyrimidine synthase 0.93 ABIE53_004817 O-succinylhomoserine sulfhydrylase 0.75 5
Paraburkholderia bryophila 376MFSha3.1 0.98 H281DRAFT_00395 hydroxymethylpyrimidine synthase 0.94 H281DRAFT_06059 O-succinylhomoserine sulfhydrylase 0.48 35
Paraburkholderia sabiae LMG 24235 0.95 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC 0.88 QEN71_RS17685 O-succinylhomoserine sulfhydrylase low > 153
Dechlorosoma suillum PS 0.85 Dsui_0422 thiamine biosynthesis protein ThiC 0.65 Dsui_3185 O-succinylhomoserine sulfhydrylase — —
Castellaniella sp019104865 MT123 0.78 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC 0.34 ABCV34_RS15785 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme low > 48
Dyella japonica UNC79MFTsu3.2 0.75 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC 0.34 ABZR86_RS18745 PLP-dependent aspartate aminotransferase family protein — —
Marinobacter adhaerens HP15 0.75 HP15_453 thiamine biosynthesis protein thiC 0.55 HP15_1820 methionine gamma-lyase 0.75 25
Pseudomonas putida KT2440 0.75 PP_4922 Phosphomethylpyrimidine synthase 0.53 PP_2001 O-succinylhomoserine sulfhydrylase 0.50 18
Rhodanobacter sp. FW510-T8 0.74 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC 0.33 OKGIIK_01180 metC cystathionine beta-lyase low > 52
Pseudomonas sp. S08-1 0.74 OH686_15885 phosphomethylpyrimidine synthase 0.56 OH686_04415 O-succinylhomoserine sulfhydrylase low > 80
Pseudomonas stutzeri RCH2 0.74 Psest_0477 thiamine biosynthesis protein ThiC 0.54 Psest_2578 O-succinylhomoserine sulfhydrylase low > 67
Pseudomonas fluorescens FW300-N2E2 0.74 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.55 Pf6N2E2_77 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 103
Xanthomonas campestris pv. campestris strain 8004 0.74 Xcc-8004.1066.1 hypothetical protein 0.33 Xcc-8004.4517.1 Cystathionine gamma-lyase (EC 4.4.1.1) low > 74
Pseudomonas fluorescens FW300-N2E3 0.74 AO353_13010 thiamine biosynthesis protein ThiC 0.55 AO353_20695 O-succinylhomoserine sulfhydrylase low > 101
Pseudomonas fluorescens FW300-N2C3 0.74 AO356_08810 thiamine biosynthesis protein ThiC 0.55 AO356_21470 O-succinylhomoserine sulfhydrylase low > 104
Pseudomonas sp. RS175 0.74 PFR28_05091 Phosphomethylpyrimidine synthase 0.55 PFR28_02810 O-succinylhomoserine sulfhydrylase low > 88
Pseudomonas fluorescens FW300-N1B4 0.73 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.33 Pf1N1B4_4890 Cystathionine gamma-lyase (EC 4.4.1.1) low > 87
Pseudomonas fluorescens SBW25-INTG 0.73 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.55 PFLU_RS20510 O-succinylhomoserine sulfhydrylase 0.42 12
Pseudomonas fluorescens SBW25 0.73 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC 0.55 PFLU_RS20510 O-succinylhomoserine sulfhydrylase low > 109
Pseudomonas fluorescens GW456-L13 0.73 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.55 PfGW456L13_3934 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.73 Psyr_0544 hydroxymethylpyrimidine synthase 0.57 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.48 23
Pseudomonas syringae pv. syringae B728a 0.73 Psyr_0544 hydroxymethylpyrimidine synthase 0.57 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.57 39
Pseudomonas simiae WCS417 0.73 PS417_02355 thiamine biosynthesis protein ThiC 0.55 PS417_18530 O-succinylhomoserine sulfhydrylase low > 88
Lysobacter sp. OAE881 0.73 ABIE51_RS17515 phosphomethylpyrimidine synthase ThiC 0.33 ABIE51_RS04295 cystathionine gamma-synthase low > 62
Mucilaginibacter yixingensis YX-36 DSM 26809 0.72 ABZR88_RS08840 phosphomethylpyrimidine synthase ThiC 0.31 ABZR88_RS06685 cystathionine gamma-synthase low > 71
Pontibacter actiniarum KMM 6156, DSM 19842 0.72 CA264_20435 phosphomethylpyrimidine synthase ThiC 0.45 CA264_02530 O-succinylhomoserine sulfhydrylase 0.61 40
Acinetobacter radioresistens SK82 0.71 MPMX26_00180 Phosphomethylpyrimidine synthase 0.58 MPMX26_01645 O-succinylhomoserine sulfhydrylase low > 36
Pedobacter sp. GW460-11-11-14-LB5 0.71 CA265_RS20165 phosphomethylpyrimidine synthase ThiC 0.46 CA265_RS13080 O-succinylhomoserine sulfhydrylase low > 88
Echinicola vietnamensis KMM 6221, DSM 17526 0.71 Echvi_3567 thiamine biosynthesis protein ThiC 0.48 Echvi_2283 Cystathionine beta-lyases/cystathionine gamma-synthases low > 79
Pectobacterium carotovorum WPP14 0.69 HER17_RS20380 phosphomethylpyrimidine synthase ThiC 0.34 HER17_RS07405 PLP-dependent aspartate aminotransferase family protein low > 75
Shewanella loihica PV-4 0.69 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq) 0.35 Shew_2491 methionine gamma-lyase (RefSeq) low > 60
Cupriavidus basilensis FW507-4G11 0.68 RR42_RS01290 thiamine biosynthesis protein ThiC 0.73 RR42_RS14320 O-succinylhomoserine sulfhydrylase 0.81 7
Shewanella amazonensis SB2B 0.68 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) 0.37 Sama_1242 methionine gamma-lyase (RefSeq) low > 62
Enterobacter sp. TBS_079 0.68 MPMX20_00217 Phosphomethylpyrimidine synthase 0.31 MPMX20_01953 Cystathionine beta-lyase low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.68 GFF4198 Thiamin biosynthesis protein ThiC 0.31 GFF2323 Cystathionine gamma-synthase (EC 2.5.1.48) low > 78
Enterobacter asburiae PDN3 0.67 EX28DRAFT_4536 phosphomethylpyrimidine synthase 0.31 EX28DRAFT_1678 Cystathionine beta-lyases/cystathionine gamma-synthases low > 76
Escherichia coli Nissle 1917 0.67 ECOLIN_RS23040 phosphomethylpyrimidine synthase ThiC 0.31 ECOLIN_RS22725 cystathionine gamma-synthase 0.58 35
Escherichia fergusonii Becca 0.67 EFB2_04617 Phosphomethylpyrimidine synthase 0.31 EFB2_04679 Cystathionine gamma-synthase low > 86
Escherichia coli ECOR27 0.67 NOLOHH_05520 thiC phosphomethylpyrimidine synthase ThiC 0.31 NOLOHH_05820 metB cystathionine gamma-synthase low > 75
Kangiella aquimarina DSM 16071 0.67 B158DRAFT_0295 hydroxymethylpyrimidine synthase 0.40 B158DRAFT_1522 methionine gamma-lyase low > 40
Escherichia coli HS(pFamp)R (ATCC 700891) 0.67 OHPLBJKB_04056 Phosphomethylpyrimidine synthase 0.31 OHPLBJKB_04111 Cystathionine gamma-synthase low > 73
Escherichia coli ECRC62 0.67 BNILDI_06005 thiC phosphomethylpyrimidine synthase ThiC 0.31 BNILDI_05715 metB cystathionine gamma-synthase low > 75
Escherichia coli BW25113 0.67 b3994 thiC thiamine biosynthesis protein ThiC (NCBI) 0.31 b3939 metB cystathionine gamma-synthase (NCBI) low > 76
Escherichia coli ECRC101 0.67 MCAODC_03875 thiC phosphomethylpyrimidine synthase ThiC 0.31 MCAODC_04175 metB cystathionine gamma-synthase low > 87
Escherichia coli ECRC99 0.67 KEDOAH_14785 thiC phosphomethylpyrimidine synthase ThiC 0.31 KEDOAH_14485 metB cystathionine gamma-synthase — —
Escherichia coli ECRC98 0.67 JDDGAC_17000 thiC phosphomethylpyrimidine synthase ThiC 0.31 JDDGAC_17300 metB cystathionine gamma-synthase low > 86
Escherichia coli ECRC100 0.67 OKFHMN_13375 thiC phosphomethylpyrimidine synthase ThiC 0.31 OKFHMN_13675 metB cystathionine gamma-synthase low > 80
Escherichia coli ECRC102 0.67 NIAGMN_11125 thiC phosphomethylpyrimidine synthase ThiC 0.31 NIAGMN_11430 metB cystathionine gamma-synthase — —
Escherichia coli BL21 0.67 ECD_03871 phosphomethylpyrimidine synthase 0.31 ECD_03825 cystathionine gamma-synthase, PLP-dependent 0.51 50
Escherichia coli ECOR38 0.67 HEPCGN_12010 thiC phosphomethylpyrimidine synthase ThiC 0.31 HEPCGN_12345 metB cystathionine gamma-synthase 0.69 68
Pantoea sp. MT58 0.67 IAI47_18085 phosphomethylpyrimidine synthase ThiC 0.28 IAI47_00880 cystathionine gamma-synthase low > 76
Klebsiella michiganensis M5al 0.67 BWI76_RS01555 phosphomethylpyrimidine synthase ThiC 0.32 BWI76_RS24210 cystathionine gamma-lyase low > 92
Dickeya dadantii 3937 0.67 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC 0.31 DDA3937_RS00950 cystathionine gamma-synthase 0.85 9
Erwinia tracheiphila SCR3 0.67 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC 0.30 LU632_RS19640 metB cystathionine gamma-synthase low > 74
Variovorax sp. SCN45 0.67 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) 0.56 GFF3088 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) — —
Shewanella oneidensis MR-1 0.67 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) 0.40 SO1812 mdeA Methionine gamma-lyase (EC 4.4.1.11) (from data) low > 76
Vibrio cholerae E7946 ATCC 55056 0.66 CSW01_00335 phosphomethylpyrimidine synthase 0.27 CSW01_13550 O-succinylhomoserine (thiol)-lyase low > 62
Shewanella sp. ANA-3 0.66 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq) 0.40 Shewana3_2643 methionine gamma-lyase (RefSeq) low > 73
Dickeya dianthicola ME23 0.66 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC 0.31 DZA65_RS21470 cystathionine gamma-synthase 0.81 15
Dickeya dianthicola 67-19 0.66 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC 0.31 HGI48_RS20425 cystathionine gamma-synthase 0.83 23
Hydrogenophaga sp. GW460-11-11-14-LB1 0.66 GFF4626 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.60 GFF301 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 90
Variovorax sp. OAS795 0.65 ABID97_RS25235 phosphomethylpyrimidine synthase ThiC 0.58 ABID97_RS21630 O-succinylhomoserine sulfhydrylase — —
Azospirillum brasilense Sp245 0.64 AZOBR_RS07940 phosphomethylpyrimidine synthase 0.46 AZOBR_RS02140 O-succinylhomoserine sulfhydrylase 0.52 25
Magnetospirillum magneticum AMB-1 0.63 AMB_RS01125 phosphomethylpyrimidine synthase 0.50 AMB_RS21365 O-succinylhomoserine sulfhydrylase — —
Sinorhizobium meliloti 1021 0.62 SM_b20615 thiamine biosynthesis protein ThiC 0.45 SMc02217 O-succinylhomoserine sulfhydrylase low > 103
Phaeobacter inhibens DSM 17395 0.62 PGA1_c09110 thiamine biosynthesis protein ThiC 0.49 PGA1_c23540 O-succinylhomoserine sulfhydrylase MetZ low > 62
Sphingomonas koreensis DSMZ 15582 0.62 Ga0059261_2424 hydroxymethylpyrimidine synthase 0.48 Ga0059261_3194 O-acetylhomoserine sulfhydrylase (EC:2.5.1.49) (from data) 0.80 64
Dinoroseobacter shibae DFL-12 0.62 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq) 0.49 Dshi_2410 O-succinylhomoserine sulfhydrylase (RefSeq) — —
Agrobacterium fabrum C58 0.62 Atu2569 thiamine biosynthesis protein 0.45 Atu0432 O-succinylhomoserine sulfhydrylase 0.72 22
Caulobacter crescentus NA1000 0.61 CCNA_02109 thiamine biosynthesis protein thiC 0.44 CCNA_02321 O-succinylhomoserine sulfhydrylase 0.71 45
Caulobacter crescentus NA1000 Δfur 0.61 CCNA_02109 thiamine biosynthesis protein thiC 0.44 CCNA_02321 O-succinylhomoserine sulfhydrylase low > 67
Brevundimonas sp. GW460-12-10-14-LB2 0.60 A4249_RS15715 phosphomethylpyrimidine synthase ThiC 0.34 A4249_RS08315 cystathionine gamma-synthase low > 48
Bosea sp. OAE506 0.60 ABIE41_RS02770 phosphomethylpyrimidine synthase ThiC 0.48 ABIE41_RS03970 O-succinylhomoserine sulfhydrylase low > 77
Rhodopseudomonas palustris CGA009 0.60 TX73_018540 phosphomethylpyrimidine synthase ThiC 0.48 TX73_024775 O-succinylhomoserine sulfhydrylase low > 86
Azospirillum sp. SherDot2 0.60 MPMX19_00336 Phosphomethylpyrimidine synthase 0.46 MPMX19_01364 O-succinylhomoserine sulfhydrylase low > 112
Rhodospirillum rubrum S1H 0.57 Rru_A2008 Thiamine biosynthesis protein ThiC (NCBI) 0.48 Rru_A3214 O-succinylhomoserine sulfhydrylase (NCBI) low > 58
Mycobacterium tuberculosis H37Rv 0.51 Rv0423c Probable thiamine biosynthesis protein ThiC 0.47 Rv0391 Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase) — —

Not shown: 16 genomes with orthologs for BPHYT_RS13220 only; 4 genomes with orthologs for BPHYT_RS33835 only