Conservation of cofitness between BPHYT_RS14785 and BPHYT_RS03495 in Burkholderia phytofirmans PsJN

79 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Burkholderia phytofirmans PsJN 1.0 BPHYT_RS14785 AsnC family transcriptional regulator 1.0 BPHYT_RS03495 hypothetical protein 0.29 5
Paraburkholderia bryophila 376MFSha3.1 0.99 H281DRAFT_04288 transcriptional regulator, AsnC family 0.89 H281DRAFT_04680 hypothetical protein low > 103
Paraburkholderia graminis OAS925 0.98 ABIE53_003132 Lrp/AsnC family leucine-responsive transcriptional regulator 0.90 ABIE53_000841 pyridoxal phosphate enzyme (YggS family) low > 113
Paraburkholderia sabiae LMG 24235 0.94 QEN71_RS04195 Lrp/AsnC ligand binding domain-containing protein 0.84 QEN71_RS26595 YggS family pyridoxal phosphate-dependent enzyme 0.49 88
Herbaspirillum seropedicae SmR1 0.84 HSERO_RS08380 AsnC family transcriptional regulator 0.59 HSERO_RS18995 hypothetical protein low > 78
Cupriavidus basilensis FW507-4G11 0.83 RR42_RS04590 AsnC family transcriptional regulator 0.57 RR42_RS17355 hypothetical protein low > 128
Ralstonia sp. UNC404CL21Col 0.82 ABZR87_RS09565 Lrp/AsnC ligand binding domain-containing protein 0.62 ABZR87_RS01225 YggS family pyridoxal phosphate-dependent enzyme low > 80
Ralstonia solanacearum UW163 0.82 UW163_RS15935 AsnC family transcriptional regulator 0.57 UW163_RS08050 YggS family pyridoxal phosphate-dependent enzyme
Ralstonia solanacearum IBSBF1503 0.82 RALBFv3_RS13875 AsnC family transcriptional regulator 0.57 RALBFv3_RS05575 YggS family pyridoxal phosphate-dependent enzyme low > 76
Ralstonia solanacearum PSI07 0.81 RPSI07_RS19595 AsnC family transcriptional regulator 0.56 RPSI07_RS11725 YggS family pyridoxal phosphate-dependent enzyme low > 81
Ralstonia solanacearum GMI1000 0.79 RS_RS04610 AsnC family transcriptional regulator 0.57 RS_RS13435 YggS family pyridoxal phosphate-dependent enzyme low > 80
Pseudomonas sp. S08-1 0.72 OH686_13680 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.58 OH686_10975 Pyridoxal phosphate-containing protein YggS low > 80
Pseudomonas syringae pv. syringae B728a 0.72 Psyr_0234 transcriptional regulator, AsnC family 0.56 Psyr_0477 Protein of unknown function UPF0001 low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.72 Psyr_0234 transcriptional regulator, AsnC family 0.56 Psyr_0477 Protein of unknown function UPF0001 low > 86
Pseudomonas putida KT2440 0.71 PP_5271 DNA-binding transcriptional dual regulator, leucine-binding 0.56 PP_5094 putative enzyme with PLP binding domain low > 96
Pseudomonas fluorescens GW456-L13 0.71 PfGW456L13_811 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.56 PfGW456L13_1011 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC low > 87
Pseudomonas fluorescens SBW25-INTG 0.70 PFLU_RS29385 AsnC family transcriptional regulator 0.57 PFLU_RS28370 YggS family pyridoxal phosphate-dependent enzyme low > 109
Pseudomonas fluorescens FW300-N1B4 0.70 Pf1N1B4_2143 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.55 Pf1N1B4_2342 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC
Pseudomonas simiae WCS417 0.70 PS417_27710 AsnC family transcriptional regulator 0.57 PS417_26725 hypothetical protein 0.19 42
Pseudomonas fluorescens SBW25 0.70 PFLU_RS29385 AsnC family transcriptional regulator 0.57 PFLU_RS28370 YggS family pyridoxal phosphate-dependent enzyme low > 109
Pseudomonas sp. RS175 0.70 PFR28_04400 Leucine-responsive regulatory protein 0.54 PFR28_04242 Pyridoxal phosphate homeostasis protein 0.32 19
Pseudomonas fluorescens FW300-N2E3 0.70 AO353_09160 AsnC family transcriptional regulator 0.53 AO353_08160 hypothetical protein low > 101
Pseudomonas fluorescens FW300-N2C3 0.70 AO356_12615 AsnC family transcriptional regulator 0.55 AO356_13425 hypothetical protein low > 104
Pseudomonas fluorescens FW300-N2E2 0.70 Pf6N2E2_4390 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.54 Pf6N2E2_4601 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC low > 103
Castellaniella sp019104865 MT123 0.70 ABCV34_RS10805 winged helix-turn-helix transcriptional regulator 0.31 ABCV34_RS02955 YggS family pyridoxal phosphate-dependent enzyme low > 48
Pseudomonas stutzeri RCH2 0.69 Psest_3794 Transcriptional regulators 0.54 Psest_0284 pyridoxal phosphate enzyme, YggS family 0.19 39
Xanthomonas campestris pv. campestris strain 8004 0.68 Xcc-8004.4622.1 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.39 Xcc-8004.1711.1 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC low > 74
Rhodanobacter denitrificans MT42 0.66 LRK55_RS00365 winged helix-turn-helix transcriptional regulator 0.31 LRK55_RS08955 YggS family pyridoxal phosphate-dependent enzyme low > 63
Rhodanobacter denitrificans FW104-10B01 0.66 LRK54_RS00595 winged helix-turn-helix transcriptional regulator 0.30 LRK54_RS02905 YggS family pyridoxal phosphate-dependent enzyme low > 59
Rhodanobacter sp. FW510-T8 0.66 OKGIIK_06660 lrp AsnC family transcriptional regulator 0.28 OKGIIK_09885 Pyridoxal phosphate homeostasis protein low > 52
Variovorax sp. OAS795 0.64 ABID97_RS22380 winged helix-turn-helix transcriptional regulator 0.60 ABID97_RS00250 YggS family pyridoxal phosphate-dependent enzyme
Variovorax sp. SCN45 0.63 GFF1774 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.61 GFF3744 Pyridoxal phosphate-containing protein YggS
Kangiella aquimarina DSM 16071 0.60 B158DRAFT_1822 Transcriptional regulators 0.43 B158DRAFT_0196 pyridoxal phosphate enzyme, YggS family low > 40
Shewanella amazonensis SB2B 0.58 Sama_1771 leucine-responsive transcriptional regulator (RefSeq) 0.49 Sama_2477 hypothetical protein (RefSeq) low > 62
Shewanella loihica PV-4 0.57 Shew_2025 leucine-responsive transcriptional regulator (RefSeq) 0.55 Shew_1137 alanine racemase domain-containing protein (RefSeq) low > 60
Vibrio cholerae E7946 ATCC 55056 0.57 CSW01_09530 leucine-responsive transcriptional regulator Lrp 0.52 CSW01_02455 YggS family pyridoxal phosphate enzyme
Shewanella oneidensis MR-1 0.56 SO2305 lrp leucine-responsive regulatory protein (NCBI ptt file) 0.54 SO3352 conserved hypothetical protein TIGR00044 (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.56 Shewana3_2049 leucine-responsive transcriptional regulator (RefSeq) 0.53 Shewana3_1194 hypothetical protein (RefSeq) 0.40 48
Dickeya dianthicola 67-19 0.56 HGI48_RS09605 leucine-responsive transcriptional regulator Lrp 0.53 HGI48_RS17345 YggS family pyridoxal phosphate-dependent enzyme low > 71
Dickeya dadantii 3937 0.56 DDA3937_RS09590 leucine-responsive transcriptional regulator Lrp 0.53 DDA3937_RS17300 YggS family pyridoxal phosphate-dependent enzyme low > 74
Dickeya dianthicola ME23 0.56 DZA65_RS09915 leucine-responsive transcriptional regulator Lrp 0.53 DZA65_RS18435 YggS family pyridoxal phosphate-dependent enzyme low > 75
Pectobacterium carotovorum WPP14 0.56 HER17_RS12360 leucine-responsive transcriptional regulator Lrp 0.54 HER17_RS03810 YggS family pyridoxal phosphate-dependent enzyme low > 75
Klebsiella michiganensis M5al 0.56 BWI76_RS09655 leucine-responsive regulatory protein 0.53 BWI76_RS24100 YggS family pyridoxal phosphate enzyme low > 92
Erwinia tracheiphila SCR3 0.55 LU632_RS09740 lrp leucine-responsive transcriptional regulator Lrp 0.50 LU632_RS05460 YggS family pyridoxal phosphate-dependent enzyme low > 74
Escherichia coli ECOR27 0.55 NOLOHH_22145 lrp leucine-responsive transcriptional regulator Lrp 0.53 NOLOHH_11125 yggS pyridoxal phosphate homeostasis protein low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.55 OHPLBJKB_02779 Leucine-responsive regulatory protein 0.53 OHPLBJKB_00765 Pyridoxal phosphate homeostasis protein low > 73
Enterobacter asburiae PDN3 0.55 EX28DRAFT_2043 transcriptional regulator, AsnC family 0.52 EX28DRAFT_2989 pyridoxal phosphate enzyme, YggS family low > 76
Enterobacter sp. TBS_079 0.55 MPMX20_01551 Leucine-responsive regulatory protein 0.51 MPMX20_03809 Pyridoxal phosphate homeostasis protein low > 85
Escherichia coli ECRC101 0.55 MCAODC_24965 lrp leucine-responsive transcriptional regulator Lrp 0.53 MCAODC_09775 yggS pyridoxal phosphate homeostasis protein low > 87
Escherichia coli Nissle 1917 0.55 ECOLIN_RS04730 leucine-responsive transcriptional regulator Lrp 0.53 ECOLIN_RS16415 pyridoxal phosphate homeostasis protein low > 55
Escherichia coli ECOR38 0.55 HEPCGN_22935 lrp leucine-responsive transcriptional regulator Lrp 0.53 HEPCGN_18560 yggS pyridoxal phosphate homeostasis protein low > 87
Pantoea sp. MT58 0.55 IAI47_12915 leucine-responsive transcriptional regulator Lrp 0.52 IAI47_03595 YggS family pyridoxal phosphate-dependent enzyme low > 76
Escherichia coli ECRC100 0.55 OKFHMN_05575 lrp leucine-responsive transcriptional regulator Lrp 0.53 OKFHMN_19255 yggS pyridoxal phosphate homeostasis protein low > 80
Escherichia fergusonii Becca 0.55 EFB2_03172 Leucine-responsive regulatory protein 0.53 EFB2_00951 Pyridoxal phosphate homeostasis protein low > 86
Escherichia coli ECRC102 0.55 NIAGMN_03295 lrp leucine-responsive transcriptional regulator Lrp 0.53 NIAGMN_17020 yggS pyridoxal phosphate homeostasis protein
Escherichia coli ECRC98 0.55 JDDGAC_09385 lrp leucine-responsive transcriptional regulator Lrp 0.53 JDDGAC_22885 yggS pyridoxal phosphate homeostasis protein low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.55 GFF4893 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.55 GFF3054 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC low > 78
Rahnella sp. WP5 0.55 EX31_RS18530 leucine-responsive transcriptional regulator Lrp 0.51 EX31_RS02685 YggS family pyridoxal phosphate-dependent enzyme low > 89
Serratia liquefaciens MT49 0.55 IAI46_08555 leucine-responsive transcriptional regulator Lrp 0.49 IAI46_21410 YggS family pyridoxal phosphate-dependent enzyme low > 86
Escherichia coli ECRC62 0.55 BNILDI_20400 lrp leucine-responsive transcriptional regulator Lrp 0.53 BNILDI_09705 yggS pyridoxal phosphate homeostasis protein low > 75
Escherichia coli BW25113 0.55 b0889 lrp DNA-binding transcriptional dual regulator, leucine-binding (NCBI) 0.53 b2951 yggS predicted enzyme (NCBI) low > 76
Escherichia coli ECRC99 0.55 KEDOAH_22160 lrp leucine-responsive transcriptional regulator Lrp 0.53 KEDOAH_08885 yggS pyridoxal phosphate homeostasis protein
Escherichia coli BL21 0.55 ECD_00893 leucine-responsive global transcriptional regulator 0.53 ECD_02781 UPF0001 family protein, PLP-binding low > 61
Alteromonas macleodii MIT1002 0.54 MIT1002_02181 Leucine-responsive regulatory protein 0.50 MIT1002_03061 pyridoxal phosphate enzyme, YggS family low > 70
Acidovorax sp. GW101-3H11 0.52 Ac3H11_2849 PutR, transcriptional activator of PutA and PutP 0.52 Ac3H11_4474 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC low > 79
Azospirillum brasilense Sp245 0.52 AZOBR_RS23685 AsnC family transcriptional regulator 0.30 AZOBR_RS01870 alanine racemase
Brevundimonas sp. GW460-12-10-14-LB2 0.51 A4249_RS13055 Lrp/AsnC ligand binding domain-containing protein 0.28 A4249_RS13760 YggS family pyridoxal phosphate-dependent enzyme low > 48
Bosea sp. OAE506 0.50 ABIE41_RS07920 Lrp/AsnC ligand binding domain-containing protein 0.30 ABIE41_RS04720 YggS family pyridoxal phosphate-dependent enzyme low > 77
Caulobacter crescentus NA1000 Δfur 0.49 CCNA_00847 leucine-responsive regulatory protein 0.27 CCNA_03861 pyridoxal 5'-phosphate dependent enzyme class III low > 67
Caulobacter crescentus NA1000 0.49 CCNA_00847 leucine-responsive regulatory protein 0.27 CCNA_03861 pyridoxal 5'-phosphate dependent enzyme class III low > 66
Hydrogenophaga sp. GW460-11-11-14-LB1 0.49 GFF2725 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.53 GFF2722 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC 0.52 47
Sinorhizobium meliloti 1021 0.48 SMc00681 leucine-responsive regulatory protein 0.30 SMc02812 hypothetical protein 0.18 54
Rhodospirillum rubrum S1H 0.47 Rru_A0655 Transcriptional Regulator, AsnC family (NCBI) 0.31 Rru_A1141 Protein of unknown function UPF0001 (NCBI) low > 58
Azospirillum sp. SherDot2 0.45 MPMX19_03947 Leucine-responsive regulatory protein 0.28 MPMX19_00050 Pyridoxal phosphate homeostasis protein low > 112
Acinetobacter radioresistens SK82 0.45 MPMX26_01467 Leucine-responsive regulatory protein 0.48 MPMX26_02404 Pyridoxal phosphate homeostasis protein low > 36
Marinobacter adhaerens HP15 0.42 HP15_2690 transcriptional regulator, AsnC family 0.50 HP15_288 alanine racemase domain protein low > 73
Agrobacterium fabrum C58 0.41 Atu4159 AsnC family transcriptional regulator 0.32 Atu2747 hypothetical protein low > 89
Rhizobium sp. OAE497 0.38 ABIE40_RS23450 Lrp/AsnC family transcriptional regulator 0.30 ABIE40_RS19180 YggS family pyridoxal phosphate-dependent enzyme
Bacteroides stercoris CC31F 0.28 HMPREF1181_RS01345 Lrp/AsnC ligand binding domain-containing protein 0.26 HMPREF1181_RS10865 YggS family pyridoxal phosphate-dependent enzyme low > 56
Mycobacterium tuberculosis H37Rv 0.25 Rv3291c Probable transcriptional regulatory protein LrpA (Lrp/AsnC-family) 0.23 Rv2148c Conserved protein low > 58

Not shown: 0 genomes with orthologs for BPHYT_RS14785 only; 22 genomes with orthologs for BPHYT_RS03495 only