| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Enterobacter sp. TBS_079 | MPMX20_04412 | | Protein YhjJ | sig. | 100 | 100 |
| o | Enterobacter asburiae PDN3 | EX28DRAFT_4050 | | Predicted Zn-dependent peptidases | cofit | 97 | 100 |
| o | Escherichia coli BL21 | ECD_03375 | | putative periplasmic M16 family chaperone | sig. | 81 | 100 |
| o | Escherichia coli ECRC100 | OKFHMN_16200 | pqqL | Insulinase (Peptidase family M16) | insig. | 81 | 100 |
| o | Escherichia coli ECRC101 | MCAODC_06715 | pqqL | Insulinase (Peptidase family M16) | insig. | 81 | 100 |
| o | Escherichia coli ECRC102 | NIAGMN_13965 | pqqL | Insulinase (Peptidase family M16) | cofit | 81 | 100 |
| o | Escherichia coli ECRC98 | JDDGAC_19830 | pqqL | Insulinase (Peptidase family M16) | insig. | 81 | 100 |
| o | Escherichia coli ECRC99 | KEDOAH_11950 | pqqL | Insulinase (Peptidase family M16) | no data | 81 | 100 |
| o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00175 | | Protein YhjJ | insig. | 81 | 100 |
| o | Escherichia coli BW25113 | b3527 | yhjJ | predicted zinc-dependent peptidase (NCBI) | strong | 81 | 100 |
| o | Escherichia coli ECOR27 | NOLOHH_08165 | pqqL | Insulinase (Peptidase family M16) | insig. | 81 | 100 |
| o | Escherichia coli ECRC62 | BNILDI_03390 | pqqL | Insulinase (Peptidase family M16) | cofit | 81 | 100 |
| o | Klebsiella pneumoniae MKP103 | KDGMDA_07495 | | Insulinase (Peptidase family M16) | sig. | 80 | 100 |
| o | Klebsiella pneumoniae MRSN742743 | GJGHJB_00239 | pqqL | Insulinase family protein | insig. | 80 | 100 |
| o | Escherichia fergusonii Becca | EFB2_00281 | | Protein YhjJ | insig. | 81 | 99 |
| o | Escherichia coli ECOR38 | HEPCGN_15105 | yhjJ | Protein YhjJ | insig. | 81 | 99 |
| o | Escherichia coli Nissle 1917 | ECOLIN_RS20175 | | pitrilysin family protein | insig. | 81 | 99 |
| o | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF496 | | Protein YhjJ, putative peptidase | insig. | 80 | 97 |
| o | Klebsiella michiganensis M5al | BWI76_RS26755 | | peptidase M16 | strong | 77 | 99 |
| o | Serratia liquefaciens MT49 | IAI46_00555 | | insulinase family protein | cofit | 66 | 96 |
| o | Pantoea sp. MT58 | IAI47_18580 | | insulinase family protein | sig. | 62 | 99 |
| o | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13516_RS18845 | | M16 family metallopeptidase | cofit | 62 | 99 |
| o | Erwinia tracheiphila SCR3 | LU632_RS00335 | | insulinase family protein | cofit | 59 | 100 |
| o | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_10170 | | peptidase M16 | cofit | 59 | 100 |
| o | Erwinia amylovora T8 | OLJFJH_04800 | | peptidase M16 | strong | 60 | 98 |
| o | Dickeya dadantii 3937 | DDA3937_RS00560 | | insulinase family protein | cofit | 59 | 97 |
| o | Dickeya dianthicola ME23 | DZA65_RS21845 | | insulinase family protein | insig. | 59 | 95 |
| o | Dickeya dianthicola 67-19 | HGI48_RS20830 | | insulinase family protein | insig. | 59 | 95 |
| o | Rahnella sp. WP5 | EX31_RS05440 | | insulinase family protein | insig. | 58 | 99 |
| o | Pectobacterium carotovorum WPP14 | HER17_RS00405 | | insulinase family protein | cofit | 56 | 100 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_08595 | | insulinase family protein | insig. | 25 | 88 |
| | Caulobacter crescentus NA1000 | CCNA_02721 | | peptidase, M16 family | no data | 22 | 85 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02721 | | peptidase, M16 family | no data | 22 | 85 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS08575 | | M16 family metallopeptidase | insig. | 23 | 84 |
| | Escherichia coli ECOR27 | NOLOHH_18920 | pqqL | putative zinc protease PqqL | insig. | 23 | 84 |
| | Escherichia coli BW25113 | b1494 | pqqL | predicted peptidase (NCBI) | insig. | 23 | 84 |
| | Escherichia coli BL21 | ECD_01452 | | putative periplasmic M16 family zinc metalloendopeptidase | insig. | 23 | 84 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_02223 | | hypothetical protein | cofit | 22 | 83 |
| | Escherichia coli ECOR38 | HEPCGN_26520 | pqqL | putative zinc protease PqqL | insig. | 22 | 84 |
| | Escherichia coli ECRC100 | OKFHMN_01280 | pqqL | putative zinc protease PqqL | cofit | 23 | 84 |
| | Escherichia coli ECRC101 | MCAODC_16660 | pqqL | putative zinc protease PqqL | insig. | 23 | 84 |
| | Escherichia coli ECRC102 | NIAGMN_25410 | pqqL | putative zinc protease PqqL | cofit | 23 | 84 |
| | Escherichia coli ECRC98 | JDDGAC_03770 | pqqL | putative zinc protease PqqL | insig. | 23 | 84 |
| | Escherichia coli ECRC99 | KEDOAH_27160 | pqqL | putative zinc protease PqqL | no data | 23 | 84 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS02280 | | insulinase family protein | cofit | 24 | 85 |
| | Escherichia coli ECRC62 | BNILDI_17410 | pqqL | putative zinc protease PqqL | insig. | 23 | 84 |
| | Shewanella oneidensis MR-1 | SO4022 | | peptidase, M16 family (NCBI ptt file) | insig. | 29 | 41 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_11470 | | peptidase M16 | insig. | 22 | 85 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS18840 | | pitrilysin family protein | cofit | 23 | 71 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1465 | | Predicted Zn-dependent peptidases | strong | 27 | 47 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_09885 | | hypothetical protein | strong | 26 | 44 |
| | Shewanella sp. ANA-3 | Shewana3_3588 | | peptidase M16 domain-containing protein (RefSeq) | cofit | 27 | 42 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU2379 | pqqL | peptidase, M16 family, putative (TIGR) | insig. | 24 | 73 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0838 | | Predicted Zn-dependent peptidases | insig. | 26 | 49 |
| | Sphingobium sp. HT1-2 | GFF3946 | | Peptidase, M16 family | cofit | 26 | 42 |
| | Pectobacterium carotovorum WPP14 | HER17_RS17245 | | insulinase family protein | insig. | 25 | 48 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS06730 | | insulinase family protein | insig. | 21 | 82 |
| | Dickeya dadantii 3937 | DDA3937_RS04385 | | insulinase family protein | insig. | 27 | 43 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS05980 | | insulinase family protein | insig. | 21 | 90 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS05860 | | insulinase family protein | sig. | 21 | 81 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS18245 | | insulinase family protein | insig. | 25 | 44 |
| | Dechlorosoma suillum PS | Dsui_1025 | | putative Zn-dependent peptidase | strong | 26 | 55 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS13970 | | pitrilysin family protein | cofit | 22 | 49 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_1428 | | Predicted Zn-dependent peptidases | strong | 23 | 45 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS07435 | | pitrilysin family protein | cofit | 25 | 45 |
| | Methylophilus sp. DMC18 | GFF762 | | putative zinc protease | cofit | 25 | 46 |
| | Pseudomonas stutzeri RCH2 | Psest_0257 | | Predicted Zn-dependent peptidases | strong | 26 | 38 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS17085 | | insulinase family protein | insig. | 21 | 49 |
| | Lysobacter sp. OAE881 | ABIE51_RS00275 | | pitrilysin family protein | insig. | 30 | 16 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_0236 | | peptidase M16 domain protein (RefSeq) | strong | 23 | 46 |
| | Pseudomonas putida KT2440 | PP_5115 | | putative Zinc protease | insig. | 26 | 44 |
| | Cellulophaga baltica 18 | M666_RS10335 | | pitrilysin family protein | insig. | 25 | 54 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1430 | | peptidase, M16 family (TIGR) | sig. | 24 | 43 |
| | Azospirillum sp. SherDot2 | MPMX19_00522 | | putative zinc protease | insig. | 24 | 84 |
| | Acinetobacter radioresistens SK82 | MPMX26_01016 | | hypothetical protein | cofit | 22 | 41 |
| | Alteromonas macleodii MIT1002 | MIT1002_01221 | | protease3 | cofit | 24 | 44 |
| | Acinetobacter baumannii LAC-4 | RR41_RS05155 | | insulinase family protein | insig. | 21 | 49 |
| | Fusobacterium nucleatum SB010 | HUW76_04970 | | insulinase family protein | cofit | 22 | 38 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c32820 | | peptidase, M16 family | strong | 22 | 44 |
| | Pseudomonas sp. DMC3 | GFF227 | | putative zinc protease | insig. | 27 | 51 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1986 | pqqL | processing protease | strong | 23 | 50 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS12705 | | insulinase family protein | insig. | 32 | 14 |
| | Shewanella oneidensis MR-1 | SO3560 | | peptidase, M16 family (NCBI ptt file) | strong | 23 | 51 |
| | Bosea sp. OAE506 | ABIE41_RS23245 | | pitrilysin family protein | insig. | 22 | 49 |
| | Acinetobacter radioresistens SK82 | MPMX26_01630 | | putative zinc protease | no data | 38 | 10 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_08255 | | peptidase M16 | sig. | 25 | 49 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_03360 | | peptidase M16 inactive domain protein | insig. | 35 | 16 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_13330 | | peptidase M16 | cofit | 26 | 49 |
| | Rhodopseudomonas palustris CGA009 | TX73_022675 | | pitrilysin family protein | cofit | 22 | 45 |
| | Shewanella loihica PV-4 | Shew_1226 | | peptidase M16 domain-containing protein (RefSeq) | strong | 30 | 18 |
| | Pseudomonas sp. RS175 | PFR28_04260 | | putative zinc protease | sig. | 26 | 49 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_05500 | | putative zinc protease | cofit | 25 | 49 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS28460 | | insulinase family protein | cofit | 25 | 49 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS28460 | | insulinase family protein | sig. | 25 | 49 |
| | Pseudomonas simiae WCS417 | PS417_26815 | | peptidase M16 | insig. | 25 | 49 |
| | Pseudomonas segetis P6 | ACVTMO_RS21915 | | M16 family metallopeptidase | strong | 25 | 48 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS04270 | | insulinase family protein | cofit | 24 | 43 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_1507 | | Predicted Zn-dependent peptidases | sig. | 23 | 44 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS17980 | | peptidase M16 | insig. | 22 | 47 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_16675 | | peptidase M16 | insig. | 21 | 82 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT3551 | | putative zinc protease (NCBI ptt file) | insig. | 34 | 15 |
| | Shewanella sp. ANA-3 | Shewana3_3161 | | peptidase M16 domain-containing protein (RefSeq) | insig. | 31 | 18 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_2322 | | FIG015547: peptidase, M16 family | insig. | 25 | 49 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_4581 | | FIG015547: peptidase, M16 family | strong | 26 | 49 |
| | Pseudomonas orientalis W4I3 | QF045_RS01215 | | pitrilysin family protein | insig. | 25 | 49 |
| | Pseudomonas protegens RBAN4 | FABNJH_29530 | | Protease 3 | insig. | 25 | 49 |
| | Shewanella amazonensis SB2B | Sama_3596 | | pseudouridine synthase, Rsu (RefSeq) | sig. | 23 | 44 |
| | Rahnella sp. WP5 | EX31_RS13165 | | pitrilysin | insig. | 25 | 46 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS20710 | | peptidase M16 | insig. | 24 | 36 |
| | Pseudomonas sp. S08-1 | OH686_14230 | | peptidase, M16 family | strong | 25 | 50 |
| | Caulobacter crescentus NA1000 | CCNA_03699 | | peptidase, M16 family | cofit | 32 | 13 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_03699 | | peptidase, M16 family | cofit | 32 | 13 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_992 | | FIG015547: peptidase, M16 family | sig. | 25 | 48 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_18335 | | peptidase M16 | sig. | 24 | 46 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS07855 | | peptidase M16 | insig. | 22 | 45 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS07535 | | pitrilysin family protein | insig. | 22 | 45 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS07805 | | insulinase family protein | cofit | 22 | 45 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS21180 | | pitrilysin family protein | insig. | 24 | 16 |