Homologs of GFF982 from Hydrogenophaga sp. GW460-11-11-14-LB1

Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
SEED: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)

Top 100 hits from BLASTp (E < 0.01)

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Orth Species Gene Name Description Fitness %Id Cov
  Hydrogenophaga sp. GW460-11-11-14-LB1 GFF982 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) insig. 100 100
o Variovorax sp. SCN45 GFF6824 Pyruvate:Oxaloacetate transcarboxylase domain protein insig. 50 96
  Azospirillum brasilense Sp245 AZOBR_RS22280 hydroxymethylglutaryl-CoA lyase strong 40 93
  Azospirillum sp. SherDot2 MPMX19_03941 3-hydroxy-3-isohexenylglutaryl-CoA/hydroxy- methylglutaryl-CoA lyase insig. 41 93
  Pseudomonas fluorescens FW300-N1B4 Pf1N1B4_3990 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) sig. 40 95
  Pseudomonas fluorescens SBW25 PFLU_RS18955 hydroxymethylglutaryl-CoA lyase cofit 41 93
  Pseudomonas fluorescens SBW25-INTG PFLU_RS18955 hydroxymethylglutaryl-CoA lyase strong 41 93
  Pseudomonas putida KT2440 PP_3540 Hydroxymethylglutaryl-CoA lyase no data 42 91
  Pseudomonas simiae WCS417 PS417_17005 hydroxymethylglutaryl-CoA lyase no data 40 93
  Dechlorosoma suillum PS Dsui_0984 isopropylmalate/homocitrate/citramalate synthase insig. 40 95
  Pseudomonas fluorescens FW300-N2E2 Pf6N2E2_2189 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) strong 40 95
  Pseudomonas sp. RS175 PFR28_01262 3-hydroxy-3-isohexenylglutaryl-CoA/hydroxy- methylglutaryl-CoA lyase no data 40 93
  Pseudomonas fluorescens FW300-N2C3 AO356_01570 hydroxymethylglutaryl-CoA lyase strong 42 91
  Lysobacter sp. OAE881 ABIE51_RS13205 hydroxymethylglutaryl-CoA lyase cofit 40 92
  Shewanella amazonensis SB2B Sama_1358 pyruvate carboxyltransferase (RefSeq) strong 39 94
  Paraburkholderia sabiae LMG 24235 QEN71_RS16990 hydroxymethylglutaryl-CoA lyase insig. 39 91
  Herbaspirillum seropedicae SmR1 HSERO_RS23475 hydroxymethylglutaryl-CoA lyase strong 39 91
  Pseudomonas sp. S08-1 OH686_00835 Hydroxymethylglutaryl-CoA lyase no data 41 91
  Shewanella loihica PV-4 Shew_2574 pyruvate carboxyltransferase (RefSeq) no data 40 93
  Pseudomonas fluorescens FW300-N2E3 AO353_20365 hydroxymethylglutaryl-CoA lyase no data 39 94
  Pseudomonas syringae pv. syringae B728a Psyr_2471 hydroxymethylglutaryl-CoA lyase insig. 40 88
  Pseudomonas syringae pv. syringae B728a ΔmexB Psyr_2471 hydroxymethylglutaryl-CoA lyase strong 40 88
  Burkholderia phytofirmans PsJN BPHYT_RS34520 hydroxymethylglutaryl-CoA lyase insig. 40 91
  Paraburkholderia graminis OAS925 ABIE53_004685 hydroxymethylglutaryl-CoA lyase insig. 39 91
  Marinobacter adhaerens HP15 HP15_1001 pyruvate carboxyltransferase no data 40 87
  Pseudomonas fluorescens GW456-L13 PfGW456L13_2594 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) strong 39 94
  Magnetospirillum magneticum AMB-1 AMB_RS03460 hydroxymethylglutaryl-CoA lyase insig. 40 92
  Marinobacter adhaerens HP15 HP15_4178 pyruvate carboxyltransferase insig. 41 87
  Rhodospirillum rubrum S1H Rru_A1940 Pyruvate carboxyltransferase (NCBI) insig. 41 90
  Paraburkholderia sabiae LMG 24235 QEN71_RS01060 hydroxymethylglutaryl-CoA lyase strong 40 90
  Shewanella oneidensis MR-1 SO1893 mvaB hydroxymethylglutaryl-CoA lyase (NCBI ptt file) no data 38 96
  Pseudomonas fluorescens GW456-L13 PfGW456L13_4547 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) insig. 36 94
  Paraburkholderia bryophila 376MFSha3.1 H281DRAFT_03571 hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) insig. 39 91
  Rhodopseudomonas palustris CGA009 TX73_013125 hydroxymethylglutaryl-CoA lyase insig. 36 95
  Paraburkholderia bryophila 376MFSha3.1 H281DRAFT_02101 hydroxymethylglutaryl-CoA lyase strong 39 90
  Pseudomonas fluorescens SBW25 PFLU_RS06990 hydroxymethylglutaryl-CoA lyase insig. 37 91
  Pseudomonas fluorescens SBW25-INTG PFLU_RS06990 hydroxymethylglutaryl-CoA lyase strong 37 91
  Shewanella sp. ANA-3 Shewana3_1668 hydroxymethylglutaryl-CoA lyase (RefSeq) no data 37 94
  Ralstonia sp. UNC404CL21Col ABZR87_RS06250 hydroxymethylglutaryl-CoA lyase strong 37 91
  Cupriavidus basilensis FW507-4G11 RR42_RS00955 hydroxymethylglutaryl-CoA lyase strong 39 92
  Burkholderia phytofirmans PsJN BPHYT_RS02130 hydroxymethylglutaryl-CoA lyase sig. 39 90
  Acidovorax sp. GW101-3H11 Ac3H11_4530 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) insig. 40 95
  Pseudomonas stutzeri RCH2 Psest_1079 Isopropylmalate/homocitrate/citramalate synthases strong 39 91
  Pseudomonas simiae WCS417 PS417_06935 hydroxymethylglutaryl-CoA lyase insig. 38 94
  Variovorax sp. SCN45 GFF2023 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) insig. 36 96
  Variovorax sp. OAS795 ABID97_RS25100 hydroxymethylglutaryl-CoA lyase strong 37 96
  Acidovorax sp. GW101-3H11 Ac3H11_3018 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) no data 37 91
  Variovorax sp. OAS795 ABID97_RS04725 hydroxymethylglutaryl-CoA lyase insig. 41 94
  Paraburkholderia graminis OAS925 ABIE53_000573 hydroxymethylglutaryl-CoA lyase strong 39 90
  Hydrogenophaga sp. GW460-11-11-14-LB1 GFF1709 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) cofit 36 96
  Hydrogenophaga sp. GW460-11-11-14-LB1 GFF3043 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) insig. 40 96
  Dinoroseobacter shibae DFL-12 Dshi_1303 Hydroxymethylglutaryl-CoA lyase (RefSeq) strong 40 88
  Kangiella aquimarina DSM 16071 B158DRAFT_2506 Isopropylmalate/homocitrate/citramalate synthases no data 37 90
  Dyella japonica UNC79MFTsu3.2 ABZR86_RS20630 hydroxymethylglutaryl-CoA lyase no data 38 88
  Pseudomonas fluorescens FW300-N2C3 AO356_24105 hydroxymethylglutaryl-CoA lyase insig. 37 93
  Agrobacterium fabrum C58 Atu3480 hydroxymethylglutaryl-CoA lyase sig. 39 91
  Rhodanobacter sp. FW510-T8 OKGIIK_09340 hydroxymethylglutaryl-CoA lyase cofit 38 87
  Caulobacter crescentus NA1000 CCNA_00500 hydroxymethylglutaryl-CoA lyase no data 36 95
  Caulobacter crescentus NA1000 Δfur CCNA_00500 hydroxymethylglutaryl-CoA lyase no data 36 95
  Cupriavidus basilensis FW507-4G11 RR42_RS13255 hydroxymethylglutaryl-CoA lyase sig. 34 93
  Variovorax sp. OAS795 ABID97_RS19460 hydroxymethylglutaryl-CoA lyase insig. 37 91
  Paraburkholderia graminis OAS925 ABIE53_006073 hydroxymethylglutaryl-CoA lyase insig. 38 95
  Ralstonia solanacearum PSI07 RPSI07_RS22880 hydroxymethylglutaryl-CoA lyase sig. 38 91
  Variovorax sp. SCN45 GFF6301 Pyruvate:Oxaloacetate transcarboxylase domain protein insig. 38 95
  Castellaniella sp019104865 MT123 ABCV34_RS14190 hydroxymethylglutaryl-CoA lyase strong 38 85
  Xanthomonas campestris pv. campestris strain 8004 Xcc-8004.2923.1 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) strong 36 91
  Phaeobacter inhibens DSM 17395 PGA1_c10340 hydroxymethylglutaryl-CoA lyase MvaB no data 38 87
  Marinobacter adhaerens HP15 HP15_2608 hydroxymethylglutaryl-CoA lyase insig. 37 91
  Paraburkholderia bryophila 376MFSha3.1 H281DRAFT_03708 hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) insig. 39 94
  Rhodanobacter denitrificans FW104-10B01 LRK54_RS02285 hydroxymethylglutaryl-CoA lyase strong 37 87
  Rhodanobacter denitrificans MT42 LRK55_RS07150 hydroxymethylglutaryl-CoA lyase cofit 36 91
  Rhodanobacter denitrificans FW104-10B01 LRK54_RS07420 hydroxymethylglutaryl-CoA lyase insig. 36 91
  Paraburkholderia sabiae LMG 24235 QEN71_RS39535 hydroxymethylglutaryl-CoA lyase insig. 38 96
  Alteromonas macleodii MIT1002 MIT1002_01665 Hydroxymethylglutaryl-CoA lyase YngG strong 35 91
  Rhodanobacter denitrificans MT42 LRK55_RS02040 hydroxymethylglutaryl-CoA lyase cofit 37 87
  Paraburkholderia graminis OAS925 ABIE53_000926 hydroxymethylglutaryl-CoA lyase insig. 36 98
  Ralstonia solanacearum IBSBF1503 RALBFv3_RS10435 hydroxymethylglutaryl-CoA lyase sig. 38 91
  Ralstonia solanacearum UW163 UW163_RS03145 hydroxymethylglutaryl-CoA lyase insig. 38 91
  Acidovorax sp. GW101-3H11 Ac3H11_199 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) insig. 37 93
  Paraburkholderia bryophila 376MFSha3.1 H281DRAFT_04763 hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) insig. 35 98
  Variovorax sp. SCN45 GFF6429 Pyruvate:Oxaloacetate transcarboxylase domain protein insig. 37 93
  Pseudomonas putida KT2440 PP_3394 putative 3-hydroxy-3-methylglutaryl-CoA lyase insig. 36 96
  Ralstonia solanacearum GMI1000 RS_RS01280 hydroxymethylglutaryl-CoA lyase cofit 38 91
  Pseudomonas stutzeri RCH2 Psest_2661 Isopropylmalate/homocitrate/citramalate synthases insig. 34 92
  Rhizobium sp. OAE497 ABIE40_RS20770 hydroxymethylglutaryl-CoA lyase strong 37 86
  Burkholderia phytofirmans PsJN BPHYT_RS03930 3-hydroxy-3-methylglutaryl-CoA lyase sig. 35 98
  Hydrogenophaga sp. GW460-11-11-14-LB1 GFF3083 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) insig. 38 97
  Paraburkholderia sabiae LMG 24235 QEN71_RS12125 hydroxymethylglutaryl-CoA lyase insig. 37 96
  Acidovorax sp. GW101-3H11 Ac3H11_370 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) insig. 34 92
  Acinetobacter radioresistens SK82 MPMX26_00628 3-hydroxy-3-isohexenylglutaryl-CoA/hydroxy- methylglutaryl-CoA lyase strong 33 89
  Paraburkholderia sabiae LMG 24235 QEN71_RS31805 hydroxymethylglutaryl-CoA lyase insig. 36 96
  Sinorhizobium meliloti 1021 SM_b21125 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) (from data) strong 36 87
  Variovorax sp. OAS795 ABID97_RS10505 hydroxymethylglutaryl-CoA lyase insig. 37 95
  Castellaniella sp019104865 MT123 ABCV34_RS08850 hydroxymethylglutaryl-CoA lyase insig. 33 91
  Brevundimonas sp. GW460-12-10-14-LB2 A4249_RS14615 hydroxymethylglutaryl-CoA lyase no data 35 93
  Pseudomonas fluorescens FW300-N2E2 Pf6N2E2_1040 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) insig. 35 93
  Paraburkholderia sabiae LMG 24235 QEN71_RS12170 hydroxymethylglutaryl-CoA lyase insig. 34 91
  Variovorax sp. SCN45 GFF2884 Pyruvate:Oxaloacetate transcarboxylase domain protein insig. 37 96
  Paraburkholderia sabiae LMG 24235 QEN71_RS30555 hydroxymethylglutaryl-CoA lyase insig. 34 90
  Cupriavidus basilensis FW507-4G11 RR42_RS25280 3-hydroxy-3-methylglutaryl-CoA lyase insig. 36 93