Conservation of cofitness between SMc03158 and SMc02659 in Sinorhizobium meliloti 1021

75 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sinorhizobium meliloti 1021 1.0 SMc03158 ABC transporter permease 1.0 SMc02659 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein 0.67 4
Rhodopseudomonas palustris CGA009 0.69 TX73_007325 ABC transporter permease 0.58 TX73_013955 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 86
Rhizobium sp. OAE497 0.69 ABIE40_RS23110 methionine ABC transporter permease 0.83 ABIE40_RS06050 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 107
Agrobacterium fabrum C58 0.69 Atu4488 ABC transporter permease 0.85 Atu1030 GTP pyrophosphohydrolase/synthetase, RelA/SpoT family low > 89
Bosea sp. OAE506 0.62 ABIE41_RS03515 methionine ABC transporter permease 0.59 ABIE41_RS19890 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 77
Rhodospirillum rubrum S1H 0.62 Rru_A2418 Binding-protein-dependent transport systems inner membrane component (NCBI) 0.46 Rru_A1856 (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA (NCBI)
Azospirillum brasilense Sp245 0.58 AZOBR_RS19470 DL-methionine transporter permease subunit 0.49 AZOBR_RS22045 GTP pyrophosphokinase
Burkholderia phytofirmans PsJN 0.55 BPHYT_RS14815 methionine ABC transporter permease 0.31 BPHYT_RS15305 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 109
Acidovorax sp. GW101-3H11 0.55 Ac3H11_632 Methionine ABC transporter permease protein 0.30 Ac3H11_3664 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Azospirillum sp. SherDot2 0.55 MPMX19_05548 D-methionine transport system permease protein MetI 0.48 MPMX19_00838 GTP pyrophosphokinase rsh low > 112
Paraburkholderia sabiae LMG 24235 0.53 QEN71_RS04165 methionine ABC transporter permease 0.31 QEN71_RS03665 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 153
Herbaspirillum seropedicae SmR1 0.53 HSERO_RS04975 methionine ABC transporter permease 0.33 HSERO_RS10635 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Hydrogenophaga sp. GW460-11-11-14-LB1 0.53 GFF5038 Methionine ABC transporter permease protein 0.29 GFF1034 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Ralstonia sp. UNC404CL21Col 0.53 ABZR87_RS09535 methionine ABC transporter permease 0.32 ABZR87_RS15225 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 80
Ralstonia solanacearum GMI1000 0.52 RS_RS04580 ABC transporter permease 0.31 RS_RS10800 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Cupriavidus basilensis FW507-4G11 0.52 RR42_RS04560 methionine ABC transporter permease 0.32 RR42_RS04920 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Paraburkholderia graminis OAS925 0.52 ABIE53_003138 D-methionine transport system permease protein 0.31 ABIE53_003230 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.18 78
Paraburkholderia bryophila 376MFSha3.1 0.52 H281DRAFT_03905 D-methionine transport system permease protein 0.31 H281DRAFT_04004 (p)ppGpp synthetase I, SpoT/RelA low > 103
Ralstonia solanacearum PSI07 0.51 RPSI07_RS19625 ABC transporter permease 0.32 RPSI07_RS13870 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 81
Ralstonia solanacearum IBSBF1503 0.51 RALBFv3_RS13845 ABC transporter permease 0.32 RALBFv3_RS03315 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 76
Ralstonia solanacearum UW163 0.51 UW163_RS15965 ABC transporter permease 0.32 UW163_RS10410 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Acinetobacter radioresistens SK82 0.49 MPMX26_01860 Methionine import system permease protein MetP 0.23 MPMX26_00539 GTP pyrophosphokinase low > 36
Pseudomonas sp. S08-1 0.49 OH686_23815 Methionine ABC transporter permease protein 0.32 OH686_13550 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase / GTP pyrophosphokinase , (p)ppGpp synthetase II low > 80
Vibrio cholerae E7946 ATCC 55056 0.48 CSW01_04640 methionine ABC transporter permease 0.30 CSW01_13675 bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase low > 62
Pseudomonas sp. RS175 0.47 PFR28_04846 D-methionine transport system permease protein MetI 0.32 PFR28_04424 Bifunctional (p)ppGpp synthase/hydrolase SpoT
Fusobacterium nucleatum SB010 0.47 HUW76_06265 ABC transporter permease 0.29 HUW76_09030 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 35
Pseudomonas fluorescens SBW25-INTG 0.47 PFLU_RS01170 ABC transporter permease 0.32 PFLU_RS29510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Pseudomonas fluorescens SBW25 0.47 PFLU_RS01170 ABC transporter permease 0.32 PFLU_RS29510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Pseudomonas fluorescens FW300-N2E3 0.46 AO353_11630 ABC transporter permease 0.32 AO353_09280 (p)ppGpp synthetase
Pseudomonas fluorescens FW300-N2E2 0.46 Pf6N2E2_3928 Methionine ABC transporter permease protein 0.32 Pf6N2E2_4361 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Pseudomonas fluorescens FW300-N2C3 0.46 AO356_10280 ABC transporter permease 0.32 AO356_12480 (p)ppGpp synthetase
Pseudomonas fluorescens GW456-L13 0.46 PfGW456L13_454 Methionine ABC transporter permease protein 0.32 PfGW456L13_780 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Klebsiella michiganensis M5al 0.44 BWI76_RS15035 metal ABC transporter permease 0.31 BWI76_RS27430 (p)ppGpp synthetase low > 92
Rahnella sp. WP5 0.44 EX31_RS15585 ABC transporter permease 0.31 EX31_RS15810 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 89
Pseudomonas syringae pv. syringae B728a ΔmexB 0.44 Psyr_0349 Binding-protein-dependent transport systems inner membrane component 0.32 Psyr_0209 RelA/SpoT protein
Pseudomonas syringae pv. syringae B728a 0.44 Psyr_0349 Binding-protein-dependent transport systems inner membrane component 0.32 Psyr_0209 RelA/SpoT protein
Pseudomonas putida KT2440 0.43 PP_0219 L,D-methionine D-methionine ABC transporter - permease subunit 0.32 PP_5302 bifunctional (p)ppGpp synthase/hydrolase
Pseudomonas simiae WCS417 0.43 PS417_01060 ABC transporter permease 0.32 PS417_27830 (p)ppGpp synthetase
Enterobacter sp. TBS_079 0.43 MPMX20_01956 Methionine import system permease protein MetP 0.31 MPMX20_00086 Bifunctional (p)ppGpp synthase/hydrolase SpoT low > 85
Enterobacter asburiae PDN3 0.43 EX28DRAFT_1675 ABC-type metal ion transport system, permease component 0.31 EX28DRAFT_3899 (p)ppGpp synthetase, RelA/SpoT family low > 76
Marinobacter adhaerens HP15 0.42 HP15_3904 binding-protein-dependent transport systems inner membrane component 0.30 HP15_305 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.36 11
Rhodanobacter sp. FW510-T8 0.42 OKGIIK_03555 metP metal ABC transporter permease 0.30 OKGIIK_12100 spoT guanosine-3',5'-bis(diphosphate) 3'-diphosphatase
Pseudomonas fluorescens FW300-N1B4 0.42 Pf1N1B4_1703 Methionine ABC transporter permease protein 0.32 Pf1N1B4_2113 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Pantoea sp. MT58 0.41 IAI47_20550 ABC transporter permease 0.31 IAI47_00510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 76
Serratia liquefaciens MT49 0.41 IAI46_07080 ABC transporter permease 0.31 IAI46_24895 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 86
Pectobacterium carotovorum WPP14 0.40 HER17_RS04375 methionine ABC transporter permease MetI 0.31 HER17_RS21385 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 75
Dickeya dadantii 3937 0.40 DDA3937_RS07980 ABC transporter permease subunit 0.31 DDA3937_RS00180 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Dechlorosoma suillum PS 0.39 Dsui_2067 ABC-type metal ion transport system, permease component 0.33 Dsui_0500 (p)ppGpp synthetase, RelA/SpoT family low > 51
Xanthomonas campestris pv. campestris strain 8004 0.39 Xcc-8004.4602.1 Methionine ABC transporter permease protein 0.30 Xcc-8004.1215.1 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Escherichia coli HS(pFamp)R (ATCC 700891) 0.39 OHPLBJKB_03463 D-methionine transport system permease protein MetI 0.31 OHPLBJKB_00051 Bifunctional (p)ppGpp synthase/hydrolase SpoT low > 73
Escherichia coli ECRC62 0.39 BNILDI_09270 metI D-methionine transport system permease protein MetI 0.31 BNILDI_04080 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 75
Escherichia coli ECRC100 0.39 OKFHMN_10055 metI D-methionine transport system permease protein MetI 0.31 OKFHMN_15555 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 80
Escherichia coli ECRC102 0.39 NIAGMN_07905 metI D-methionine transport system permease protein MetI 0.31 NIAGMN_13315 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Escherichia coli ECOR27 0.39 NOLOHH_02400 metI D-methionine transport system permease protein MetI 0.31 NOLOHH_07435 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 75
Escherichia coli BL21 0.39 ECD_00197 DL-methionine transporter subunit 0.31 ECD_03507 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 0.34 53
Escherichia coli ECRC98 0.39 JDDGAC_13650 metI D-methionine transport system permease protein MetI 0.31 JDDGAC_19180 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 86
Escherichia coli ECRC99 0.39 KEDOAH_18100 metI D-methionine transport system permease protein MetI 0.31 KEDOAH_12590 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Escherichia coli Nissle 1917 0.39 ECOLIN_RS01090 methionine ABC transporter permease MetI 0.31 ECOLIN_RS20790 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 55
Escherichia coli BW25113 0.39 b0198 metI DL-methionine transporter subunit (NCBI) 0.31 b3650 spoT bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) low > 76
Escherichia coli ECOR38 0.39 HEPCGN_07995 metI D-methionine transport system permease protein MetI 0.31 HEPCGN_14375 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 87
Escherichia fergusonii Becca 0.39 EFB2_03845 D-methionine transport system permease protein MetI 0.31 EFB2_00138 Bifunctional (p)ppGpp synthase/hydrolase SpoT low > 86
Escherichia coli ECRC101 0.39 MCAODC_00570 metI D-methionine transport system permease protein MetI 0.31 MCAODC_06065 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 87
Dickeya dianthicola ME23 0.39 DZA65_RS17995 methionine ABC transporter permease MetI 0.31 DZA65_RS22150 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Dickeya dianthicola 67-19 0.39 HGI48_RS16920 methionine ABC transporter permease MetI 0.31 HGI48_RS21180 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.38 GFF22 Methionine ABC transporter permease protein 0.31 GFF357 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 low > 78
Variovorax sp. SCN45 0.38 GFF3113 Methionine ABC transporter permease protein 0.31 GFF2375 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II
Variovorax sp. OAS795 0.38 ABID97_RS21740 methionine ABC transporter permease 0.30 ABID97_RS23670 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Rhodanobacter denitrificans MT42 0.37 LRK55_RS14445 methionine ABC transporter permease 0.30 LRK55_RS11520 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Rhodanobacter denitrificans FW104-10B01 0.37 LRK54_RS14730 ABC transporter permease 0.30 LRK54_RS11795 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Dyella japonica UNC79MFTsu3.2 0.37 ABZR86_RS00470 methionine ABC transporter permease 0.31 ABZR86_RS11850 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Castellaniella sp019104865 MT123 0.37 ABCV34_RS09540 methionine ABC transporter permease 0.32 ABCV34_RS03095 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Pseudomonas stutzeri RCH2 0.36 Psest_4315 ABC-type metal ion transport system, permease component 0.31 Psest_3817 (p)ppGpp synthetase, RelA/SpoT family
Caulobacter crescentus NA1000 Δfur 0.33 CCNA_02750 ABC transporter permease protein 0.43 CCNA_01622 Rsh ppGpp hydrolase-synthetase low > 67
Caulobacter crescentus NA1000 0.33 CCNA_02750 ABC transporter permease protein 0.43 CCNA_01622 Rsh ppGpp hydrolase-synthetase low > 66
Erwinia tracheiphila SCR3 0.33 LU632_RS19825 methionine ABC transporter permease MetI 0.31 LU632_RS22200 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 74
Bifidobacterium breve UCC2003 0.28 BBR_RS14455 ABC transporter permease 0.28 BBR_RS16410 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase

Not shown: 0 genomes with orthologs for SMc03158 only; 26 genomes with orthologs for SMc02659 only