Conservation of cofitness between GFF4142 and GFF4626 in Hydrogenophaga sp. GW460-11-11-14-LB1

60 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Hydrogenophaga sp. GW460-11-11-14-LB1 1.0 GFF4142 transcriptional regulator, Crp/Fnr family 1.0 GFF4626 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) 0.37 19
Acidovorax sp. GW101-3H11 0.81 Ac3H11_975 transcriptional regulator, Crp/Fnr family 0.81 Ac3H11_2027 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17)
Dechlorosoma suillum PS 0.68 Dsui_1646 cAMP-binding protein 0.67 Dsui_0422 thiamine biosynthesis protein ThiC
Pseudomonas fluorescens FW300-N2C3 0.56 AO356_23940 Crp/Fnr family transcriptional regulator 0.67 AO356_08810 thiamine biosynthesis protein ThiC low > 104
Pseudomonas fluorescens FW300-N2E2 0.55 Pf6N2E2_1516 transcriptional regulator, Crp/Fnr family 0.67 Pf6N2E2_3644 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) low > 103
Pseudomonas sp. RS175 0.55 PFR28_02314 Fumarate and nitrate reduction regulatory protein 0.67 PFR28_05091 Phosphomethylpyrimidine synthase low > 88
Pseudomonas simiae WCS417 0.54 PS417_15825 Crp/Fnr family transcriptional regulator 0.67 PS417_02355 thiamine biosynthesis protein ThiC low > 88
Pseudomonas fluorescens FW300-N2E3 0.54 AO353_19870 Crp/Fnr family transcriptional regulator 0.66 AO353_13010 thiamine biosynthesis protein ThiC low > 101
Pseudomonas fluorescens FW300-N1B4 0.53 Pf1N1B4_4177 transcriptional regulator, Crp/Fnr family 0.67 Pf1N1B4_1447 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) low > 87
Ralstonia sp. UNC404CL21Col 0.53 ABZR87_RS11180 fumarate/nitrate reduction transcriptional regulator Fnr 0.63 ABZR87_RS04785 phosphomethylpyrimidine synthase ThiC low > 80
Paraburkholderia sabiae LMG 24235 0.53 QEN71_RS36970 fumarate/nitrate reduction transcriptional regulator Fnr 0.68 QEN71_RS05480 phosphomethylpyrimidine synthase ThiC low > 153
Ralstonia solanacearum UW163 0.53 UW163_RS13110 fumarate/nitrate reduction transcriptional regulator Fnr 0.63 UW163_RS03640 phosphomethylpyrimidine synthase ThiC
Ralstonia solanacearum IBSBF1503 0.53 RALBFv3_RS15650 fumarate/nitrate reduction transcriptional regulator Fnr 0.63 RALBFv3_RS09940 phosphomethylpyrimidine synthase ThiC low > 76
Ralstonia solanacearum PSI07 0.52 RPSI07_RS17705 fumarate/nitrate reduction transcriptional regulator Fnr 0.63 RPSI07_RS23420 phosphomethylpyrimidine synthase ThiC low > 81
Ralstonia solanacearum GMI1000 0.52 RS_RS06430 fumarate/nitrate reduction transcriptional regulator Fnr 0.62 RS_RS00555 phosphomethylpyrimidine synthase low > 80
Paraburkholderia bryophila 376MFSha3.1 0.51 H281DRAFT_01640 transcriptional regulator, Crp/Fnr family 0.67 H281DRAFT_00395 hydroxymethylpyrimidine synthase low > 103
Burkholderia phytofirmans PsJN 0.50 BPHYT_RS31300 Crp/Fnr family transcriptional regulator 0.67 BPHYT_RS13220 phosphomethylpyrimidine synthase low > 109
Paraburkholderia graminis OAS925 0.48 ABIE53_004332 CRP/FNR family transcriptional regulator 0.67 ABIE53_002857 phosphomethylpyrimidine synthase low > 113
Herbaspirillum seropedicae SmR1 0.48 HSERO_RS12690 transcriptional regulator 0.68 HSERO_RS02120 phosphomethylpyrimidine synthase ThiC low > 78
Castellaniella sp019104865 MT123 0.45 ABCV34_RS06835 helix-turn-helix domain-containing protein 0.69 ABCV34_RS10825 phosphomethylpyrimidine synthase ThiC low > 48
Pseudomonas putida KT2440 0.45 PP_3287 transcriptional regulator with 4Fe-4S cluster; Crp/Fnr family 0.67 PP_4922 Phosphomethylpyrimidine synthase low > 96
Pseudomonas fluorescens SBW25-INTG 0.41 PFLU_RS22395 fumarate/nitrate reduction transcriptional regulator Fnr 0.67 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC low > 109
Shewanella amazonensis SB2B 0.41 Sama_1799 fumarate/nitrate reduction transcriptional regulator (RefSeq) 0.63 Sama_1860 thiamine biosynthesis protein ThiC (RefSeq) low > 62
Dickeya dianthicola 67-19 0.41 HGI48_RS10900 fumarate/nitrate reduction transcriptional regulator Fnr 0.63 HGI48_RS01170 phosphomethylpyrimidine synthase ThiC low > 71
Enterobacter sp. TBS_079 0.41 MPMX20_02035 Fumarate and nitrate reduction regulatory protein 0.64 MPMX20_00217 Phosphomethylpyrimidine synthase low > 85
Dickeya dianthicola ME23 0.41 DZA65_RS11360 fumarate/nitrate reduction transcriptional regulator Fnr 0.63 DZA65_RS01215 phosphomethylpyrimidine synthase ThiC low > 75
Pseudomonas fluorescens SBW25 0.41 PFLU_RS22395 fumarate/nitrate reduction transcriptional regulator Fnr 0.67 PFLU_RS02430 phosphomethylpyrimidine synthase ThiC low > 109
Shewanella loihica PV-4 0.41 Shew_1993 fumarate/nitrate reduction transcriptional regulator (RefSeq) 0.63 Shew_2096 thiamine biosynthesis protein ThiC (RefSeq)
Alteromonas macleodii MIT1002 0.41 MIT1002_02137 Fumarate and nitrate reduction regulatory protein 0.64 MIT1002_00097 Phosphomethylpyrimidine synthase 0.76 50
Pectobacterium carotovorum WPP14 0.41 HER17_RS10525 fumarate/nitrate reduction transcriptional regulator Fnr 0.63 HER17_RS20380 phosphomethylpyrimidine synthase ThiC low > 75
Serratia liquefaciens MT49 0.41 IAI46_13260 FNR family transcription factor 0.63 IAI46_01320 phosphomethylpyrimidine synthase ThiC low > 86
Dickeya dadantii 3937 0.41 DDA3937_RS10950 fumarate/nitrate reduction transcriptional regulator Fnr 0.64 DDA3937_RS01175 phosphomethylpyrimidine synthase ThiC low > 74
Pseudomonas sp. S08-1 0.41 OH686_02245 Fumarate and nitrate reduction regulatory protein 0.67 OH686_15885 phosphomethylpyrimidine synthase low > 80
Rahnella sp. WP5 0.41 EX31_RS07200 FNR family transcription factor 0.64 EX31_RS16815 phosphomethylpyrimidine synthase ThiC low > 89
Pseudomonas stutzeri RCH2 0.41 Psest_2538 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases 0.67 Psest_0477 thiamine biosynthesis protein ThiC low > 67
Shewanella sp. ANA-3 0.41 Shewana3_2115 fumarate/nitrate reduction transcriptional regulator (RefSeq) 0.62 Shewana3_1936 thiamine biosynthesis protein ThiC (RefSeq)
Shewanella oneidensis MR-1 0.40 SO2356 etrA electron transport regulator a (NCBI ptt file) 0.62 SO2445 thiC thiamin biosynthesis protein ThiC (NCBI ptt file) low > 76
Pseudomonas fluorescens GW456-L13 0.40 PfGW456L13_4071 Fumarate and nitrate reduction regulatory protein 0.67 PfGW456L13_187 Hydroxymethylpyrimidine phosphate synthase ThiC (EC 4.1.99.17) low > 87
Vibrio cholerae E7946 ATCC 55056 0.40 CSW01_07190 transcriptional regulator FNR 0.62 CSW01_00335 phosphomethylpyrimidine synthase low > 62
Erwinia tracheiphila SCR3 0.40 LU632_RS11420 FNR family transcription factor 0.64 LU632_RS00970 thiC phosphomethylpyrimidine synthase ThiC low > 74
Pseudomonas syringae pv. syringae B728a ΔmexB 0.40 Psyr_3425 Cyclic nucleotide-binding:Bacterial regulatory protein, Crp 0.66 Psyr_0544 hydroxymethylpyrimidine synthase
Pseudomonas syringae pv. syringae B728a 0.40 Psyr_3425 Cyclic nucleotide-binding:Bacterial regulatory protein, Crp 0.66 Psyr_0544 hydroxymethylpyrimidine synthase low > 86
Marinobacter adhaerens HP15 0.40 HP15_634 transcriptional regulator, Crp/Fnr family 0.67 HP15_453 thiamine biosynthesis protein thiC low > 73
Lysobacter sp. OAE881 0.40 ABIE51_RS03805 fumarate/nitrate reduction transcriptional regulator Fnr 0.66 ABIE51_RS17515 phosphomethylpyrimidine synthase ThiC low > 62
Kangiella aquimarina DSM 16071 0.39 B158DRAFT_1982 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases 0.71 B158DRAFT_0295 hydroxymethylpyrimidine synthase low > 40
Rhodanobacter sp. FW510-T8 0.38 OKGIIK_00820 CRP-like protein Clp 0.67 OKGIIK_16965 thiC phosphomethylpyrimidine synthase ThiC low > 52
Variovorax sp. SCN45 0.29 GFF6947 transcriptional regulator, Crp/Fnr family 0.83 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) low > 127
Dyella japonica UNC79MFTsu3.2 0.29 ABZR86_RS04345 cyclic nucleotide-binding domain-containing protein 0.67 ABZR86_RS17230 phosphomethylpyrimidine synthase ThiC low > 74
Azospirillum brasilense Sp245 0.27 AZOBR_RS01145 Crp/Fnr family transcriptional regulator 0.66 AZOBR_RS07940 phosphomethylpyrimidine synthase low > 97
Xanthomonas campestris pv. campestris strain 8004 0.24 Xcc-8004.2952.1 transcriptional regulator, Crp/Fnr family 0.65 Xcc-8004.1066.1 hypothetical protein low > 74
Rhodospirillum rubrum S1H 0.24 Rru_A3322 Transcriptional Regulator, Crp/Fnr family (NCBI) 0.60 Rru_A2008 Thiamine biosynthesis protein ThiC (NCBI) low > 58
Magnetospirillum magneticum AMB-1 0.21 AMB_RS22105 transcriptional regulator 0.63 AMB_RS01125 phosphomethylpyrimidine synthase
Agrobacterium fabrum C58 0.19 Atu1602 transcriptional activator, Crp family 0.64 Atu2569 thiamine biosynthesis protein low > 89
Caulobacter crescentus NA1000 Δfur 0.17 CCNA_00789 hypoxia transcriptional regulator FixK 0.65 CCNA_02109 thiamine biosynthesis protein thiC low > 67
Caulobacter crescentus NA1000 0.17 CCNA_00789 hypoxia transcriptional regulator FixK 0.65 CCNA_02109 thiamine biosynthesis protein thiC 0.85 9
Sinorhizobium meliloti 1021 0.16 SMa1225 transcriptional regulator FixK 0.64 SM_b20615 thiamine biosynthesis protein ThiC
Rhodopseudomonas palustris CGA009 0.16 TX73_022020 helix-turn-helix domain-containing protein 0.63 TX73_018540 phosphomethylpyrimidine synthase ThiC
Bosea sp. OAE506 0.16 ABIE41_RS04120 Crp/Fnr family transcriptional regulator 0.63 ABIE41_RS02770 phosphomethylpyrimidine synthase ThiC low > 77
Dinoroseobacter shibae DFL-12 0.15 Dshi_0660 transcriptional regulator, Crp/Fnr family (RefSeq) 0.64 Dshi_4080 thiamine biosynthesis protein ThiC (RefSeq)
Sphingomonas koreensis DSMZ 15582 0.15 Ga0059261_1530 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases 0.64 Ga0059261_2424 hydroxymethylpyrimidine synthase low > 68
Brevundimonas sp. GW460-12-10-14-LB2 0.12 A4249_RS05295 Crp/Fnr family transcriptional regulator 0.64 A4249_RS15715 phosphomethylpyrimidine synthase ThiC low > 48

Not shown: 22 genomes with orthologs for GFF4142 only; 12 genomes with orthologs for GFF4626 only