| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Pseudomonas stutzeri RCH2 | 1.0 | Psest_2405 | | NAD-dependent protein deacetylases, SIR2 family | 1.0 | Psest_2589 | | 3-isopropylmalate dehydrogenase | 0.26 | 1 |
| Pseudomonas sp. S08-1 | 0.63 | OH686_06015 | | NAD-dependent protein deacetylase of SIR2 family | 0.91 | OH686_04470 | | 3-isopropylmalate dehydrogenase | low | > 80 |
| Pseudomonas putida KT2440 | 0.52 | PP_5402 | | deacetylase of acetyl-CoA synthetase, NAD-dependent | 0.87 | PP_1988 | | 3-isopropylmalate dehydrogenase | low | > 96 |
| Pseudomonas fluorescens FW300-N2C3 | 0.52 | AO356_23430 | | NAD-dependent deacetylase | 0.88 | AO356_21415 | | 3-isopropylmalate dehydrogenase | low | > 104 |
| Ralstonia sp. UNC404CL21Col | 0.48 | ABZR87_RS10995 | | NAD-dependent deacylase | 0.63 | ABZR87_RS14530 | | 3-isopropylmalate dehydrogenase | low | > 80 |
| Ralstonia solanacearum PSI07 | 0.48 | RPSI07_RS18020 | | NAD-dependent deacylase | 0.62 | RPSI07_RS14705 | | 3-isopropylmalate dehydrogenase | low | > 81 |
| Ralstonia solanacearum GMI1000 | 0.46 | RS_RS06165 | | NAD-dependent deacylase | 0.62 | RS_RS09990 | | 3-isopropylmalate dehydrogenase | low | > 80 |
| Ralstonia solanacearum IBSBF1503 | 0.46 | RALBFv3_RS15355 | | NAD-dependent deacylase | 0.62 | RALBFv3_RS02610 | | 3-isopropylmalate dehydrogenase | low | > 76 |
| Ralstonia solanacearum UW163 | 0.46 | UW163_RS12820 | | NAD-dependent deacylase | 0.62 | UW163_RS11115 | | 3-isopropylmalate dehydrogenase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.43 | RR42_RS13055 | | NAD-dependent protein deacylase | 0.62 | RR42_RS14385 | | 3-isopropylmalate dehydrogenase | low | > 128 |
| Kangiella aquimarina DSM 16071 | 0.42 | B158DRAFT_0796 | | NAD-dependent protein deacetylases, SIR2 family | 0.69 | B158DRAFT_1322 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | low | > 40 |
| Mycobacterium tuberculosis H37Rv | 0.42 | Rv1151c | | Transcriptional regulatory protein | 0.28 | Rv2995c | | Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) | — | — |
| Acidovorax sp. GW101-3H11 | 0.40 | Ac3H11_4140 | | NAD-dependent protein deacetylase of SIR2 family | 0.63 | Ac3H11_1528 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | low | > 79 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.38 | GFF4837 | | NAD-dependent protein deacetylase of SIR2 family | 0.63 | GFF3360 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | low | > 90 |
| Vibrio cholerae E7946 ATCC 55056 | 0.35 | CSW01_07575 | | NAD-dependent protein deacylase | 0.51 | CSW01_12600 | | 3-isopropylmalate dehydrogenase | low | > 62 |
| Azospirillum brasilense Sp245 | 0.33 | AZOBR_RS00620 | | NAD-dependent deacetylase | 0.53 | AZOBR_RS14130 | | 3-isopropylmalate dehydrogenase | low | > 97 |
| Pantoea sp. MT58 | 0.32 | IAI47_11950 | | NAD-dependent protein deacylase | 0.49 | IAI47_16005 | | 3-isopropylmalate dehydrogenase | low | > 76 |
| Shewanella amazonensis SB2B | 0.32 | Sama_1435 | | NAD-dependent deacetylase (RefSeq) | 0.51 | Sama_0336 | | 3-isopropylmalate dehydrogenase (RefSeq) | 0.52 | 61 |
| Bacteroides ovatus ATCC 8483 | 0.31 | BACOVA_02197 | | transcriptional regulator, Sir2 family | 0.41 | BACOVA_04600 | | 3-isopropylmalate dehydrogenase | low | > 94 |
| Shewanella sp. ANA-3 | 0.31 | Shewana3_1717 | | NAD-dependent deacetylase (RefSeq) | 0.51 | Shewana3_3760 | | 3-isopropylmalate dehydrogenase (RefSeq) | — | — |
| Shewanella oneidensis MR-1 | 0.31 | SO1938 | cobB | cobB protein (NCBI ptt file) | 0.51 | SO4235 | leuB | 3-isopropylmalate dehydrogenase (NCBI ptt file) | low | > 76 |
| Caulobacter crescentus NA1000 | 0.31 | CCNA_03594 | | SIR2 family protein | 0.50 | CCNA_00193 | | 3-isopropylmalate dehydrogenase | low | > 66 |
| Variovorax sp. SCN45 | 0.31 | GFF5049 | | NAD-dependent protein deacetylase of SIR2 family | 0.63 | GFF3888 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | low | > 127 |
| Caulobacter crescentus NA1000 Δfur | 0.31 | CCNA_03594 | | SIR2 family protein | 0.50 | CCNA_00193 | | 3-isopropylmalate dehydrogenase | low | > 67 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.31 | BT2975 | | putative nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (NCBI ptt file) | 0.42 | BT1857 | | 3-isopropylmalate dehydrogenase (NCBI ptt file) | low | > 81 |
| Pectobacterium carotovorum WPP14 | 0.31 | HER17_RS08800 | | NAD-dependent protein deacylase | 0.51 | HER17_RS03080 | | 3-isopropylmalate dehydrogenase | low | > 75 |
| Parabacteroides merdae CL09T00C40 | 0.30 | HMPREF1078_RS12815 | | NAD-dependent deacylase | 0.44 | HMPREF1078_RS16640 | | 3-isopropylmalate dehydrogenase | low | > 61 |
| Bacteroides stercoris CC31F | 0.30 | HMPREF1181_RS01330 | | NAD-dependent deacylase | 0.43 | HMPREF1181_RS14125 | | 3-isopropylmalate dehydrogenase | low | > 56 |
| Alteromonas macleodii MIT1002 | 0.30 | MIT1002_02145 | | NAD-dependent protein deacylase | 0.50 | MIT1002_00948 | | 3-isopropylmalate dehydrogenase | low | > 70 |
| Azospirillum sp. SherDot2 | 0.30 | MPMX19_02648 | | NAD-dependent protein deacylase | 0.56 | MPMX19_00607 | | 3-isopropylmalate dehydrogenase | low | > 112 |
| Rhodospirillum rubrum S1H | 0.30 | Rru_A3645 | | Silent information regulator protein Sir2 (NCBI) | 0.56 | Rru_A1191 | | 3-isopropylmalate dehydrogenase (NCBI) | low | > 58 |
| Escherichia coli ECRC101 | 0.30 | OKFHMN_03440 | cobB | NAD-dependent protein deacylase | 0.52 | OKFHMN_10720 | leuB | 3-isopropylmalate dehydrogenase | — | — |
| Escherichia coli BL21 | 0.30 | ECD_01118 | | deacetylase of acs and cheY, chemotaxis regulator | 0.51 | ECD_00075 | | 3-isopropylmalate dehydrogenase, NAD(+)-dependent | low | > 60 |
| Escherichia coli ECRC101 | 0.30 | MCAODC_22800 | cobB | NAD-dependent protein deacylase | 0.52 | MCAODC_01235 | leuB | 3-isopropylmalate dehydrogenase | — | — |
| Escherichia coli ECOR38 | 0.30 | HEPCGN_24045 | cobB | NAD-dependent protein deacylase | 0.52 | HEPCGN_08700 | leuB | 3-isopropylmalate dehydrogenase | low | > 85 |
| Escherichia coli BW25113 | 0.30 | b1120 | cobB | deacetylase of acs and cheY, regulates chemotaxis (NCBI) | 0.51 | b0073 | leuB | 3-isopropylmalate dehydrogenase (VIMSS) | low | > 76 |
| Escherichia fergusonii Becca | 0.30 | EFB2_02855 | | NAD-dependent protein deacylase | 0.52 | EFB2_03972 | | 3-isopropylmalate dehydrogenase | low | > 86 |
| Escherichia coli ECRC62 | 0.30 | BNILDI_19130 | cobB | NAD-dependent protein deacylase | 0.51 | BNILDI_08545 | leuA | 2-isopropylmalate synthase | — | — |
| Escherichia coli Nissle 1917 | 0.30 | ECOLIN_RS06455 | | Sir2 family NAD+-dependent deacetylase | 0.52 | ECOLIN_RS00395 | | 3-isopropylmalate dehydrogenase | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.30 | OHPLBJKB_02546 | | NAD-dependent protein deacylase | 0.51 | OHPLBJKB_03584 | | 3-isopropylmalate dehydrogenase | low | > 73 |
| Escherichia coli ECRC102 | 0.30 | NIAGMN_24390 | cobB | NAD-dependent protein deacylase | 0.52 | NIAGMN_08570 | leuB | 3-isopropylmalate dehydrogenase | — | — |
| Rahnella sp. WP5 | 0.30 | EX31_RS24540 | | NAD-dependent protein deacylase | 0.51 | EX31_RS03685 | | 3-isopropylmalate dehydrogenase | low | > 89 |
| Escherichia coli ECRC98 | 0.30 | JDDGAC_07100 | cobB | NAD-dependent protein deacylase | 0.52 | JDDGAC_14315 | leuB | 3-isopropylmalate dehydrogenase | — | — |
| Shewanella loihica PV-4 | 0.30 | Shew_1662 | | NAD-dependent deacetylase (RefSeq) | 0.51 | Shew_3471 | | 3-isopropylmalate dehydrogenase (RefSeq) | low | > 60 |
| Escherichia coli ECRC99 | 0.30 | KEDOAH_24315 | cobB | NAD-dependent protein deacylase | 0.52 | KEDOAH_17435 | leuB | 3-isopropylmalate dehydrogenase | — | — |
| Phocaeicola dorei CL03T12C01 | 0.30 | ABI39_RS04165 | | NAD-dependent deacylase | 0.42 | ABI39_RS10215 | | 3-isopropylmalate dehydrogenase | low | > 72 |
| Phocaeicola vulgatus CL09T03C04 | 0.30 | HMPREF1058_RS12545 | | NAD-dependent deacylase | 0.42 | HMPREF1058_RS14565 | | 3-isopropylmalate dehydrogenase | low | > 67 |
| Escherichia coli ECOR27 | 0.30 | NOLOHH_20965 | cobB | NAD-dependent protein deacylase | 0.51 | NOLOHH_03065 | leuA | 2-isopropylmalate synthase | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.30 | GFF3403 | | NAD-dependent protein deacetylase of SIR2 family | 0.52 | GFF165 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | low | > 78 |
| Marinobacter adhaerens HP15 | 0.29 | HP15_2552 | | silent information regulator protein Sir2 | 0.69 | HP15_1832 | | 3-isopropylmalate dehydrogenase | low | > 73 |
| Acinetobacter radioresistens SK82 | 0.29 | MPMX26_01708 | | NAD-dependent protein deacylase | 0.70 | MPMX26_00348 | | 3-isopropylmalate dehydrogenase | — | — |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.29 | Echvi_3134 | | NAD-dependent protein deacetylases, SIR2 family | 0.43 | Echvi_2062 | | 3-isopropylmalate dehydrogenase | — | — |
| Dickeya dianthicola ME23 | 0.28 | DZA65_RS13510 | | NAD-dependent protein deacylase | 0.51 | DZA65_RS19205 | | 3-isopropylmalate dehydrogenase | low | > 75 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.28 | A4249_RS00415 | | NAD-dependent deacylase | 0.45 | A4249_RS09995 | | 3-isopropylmalate dehydrogenase | low | > 48 |
| Magnetospirillum magneticum AMB-1 | 0.28 | AMB_RS04415 | | NAD-dependent protein deacylase | 0.55 | AMB_RS20570 | | 3-isopropylmalate dehydrogenase | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.28 | Ga0059261_1943 | | NAD-dependent protein deacetylases, SIR2 family | 0.55 | Ga0059261_3190 | | 3-isopropylmalate dehydrogenase | low | > 68 |
| Dickeya dadantii 3937 | 0.28 | DDA3937_RS12975 | | NAD-dependent protein deacylase | 0.51 | DDA3937_RS18120 | | 3-isopropylmalate dehydrogenase | low | > 74 |
| Dinoroseobacter shibae DFL-12 | 0.27 | Dshi_2612 | | Silent information regulator protein Sir2 (RefSeq) | 0.57 | Dshi_0081 | | 3-isopropylmalate dehydrogenase (RefSeq) | — | — |
| Dickeya dianthicola 67-19 | 0.27 | HGI48_RS13045 | | NAD-dependent protein deacylase | 0.51 | HGI48_RS18060 | | 3-isopropylmalate dehydrogenase | low | > 71 |
| Erwinia tracheiphila SCR3 | 0.27 | LU632_RS14640 | cobB | NAD-dependent protein deacylase | 0.48 | LU632_RS02875 | leuB | 3-isopropylmalate dehydrogenase | low | > 74 |
| Pseudomonas fluorescens FW300-N2E2 | 0.25 | Pf6N2E2_2109 | | NAD-dependent protein deacetylase of SIR2 family | 0.88 | Pf6N2E2_66 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | low | > 103 |
| Herbaspirillum seropedicae SmR1 | 0.23 | HSERO_RS18330 | | NAD-dependent deacetylase | 0.63 | HSERO_RS16500 | | 3-isopropylmalate dehydrogenase | low | > 78 |
| Pseudomonas simiae WCS417 | 0.23 | PS417_10540 | | NAD-dependent deacetylase | 0.87 | PS417_18585 | | 3-isopropylmalate dehydrogenase | low | > 88 |
| Dyella japonica UNC79MFTsu3.2 | 0.23 | ABZR86_RS05345 | | NAD-dependent protein deacetylase | 0.42 | ABZR86_RS15950 | | 3-isopropylmalate dehydrogenase | low | > 74 |
| Lysobacter sp. OAE881 | 0.22 | ABIE51_RS09130 | | NAD-dependent protein deacetylase | 0.48 | ABIE51_RS17585 | | 3-isopropylmalate dehydrogenase | low | > 62 |
| Bosea sp. OAE506 | 0.22 | ABIE41_RS14930 | | Sir2 family NAD-dependent protein deacetylase | 0.52 | ABIE41_RS11860 | | 3-isopropylmalate dehydrogenase | — | — |
| Pseudomonas fluorescens SBW25 | 0.22 | PFLU_RS10600 | | NAD-dependent protein deacetylase | 0.87 | PFLU_RS20565 | | 3-isopropylmalate dehydrogenase | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.22 | PFLU_RS10600 | | NAD-dependent protein deacetylase | 0.87 | PFLU_RS20565 | | 3-isopropylmalate dehydrogenase | low | > 109 |
| Rhodanobacter sp. FW510-T8 | 0.22 | OKGIIK_08275 | | NAD-dependent protein deacetylase | 0.44 | OKGIIK_13595 | leuB | 3-isopropylmalate dehydrogenase | low | > 52 |
| Rhodopseudomonas palustris CGA009 | 0.22 | TX73_013035 | | NAD-dependent protein deacetylase | 0.51 | TX73_001175 | | 3-isopropylmalate dehydrogenase | — | — |
| Rhodanobacter denitrificans MT42 | 0.21 | LRK55_RS16230 | | NAD-dependent protein deacetylase | 0.44 | LRK55_RS09965 | | 3-isopropylmalate dehydrogenase | low | > 63 |
| Rhodanobacter denitrificans FW104-10B01 | 0.21 | LRK54_RS16480 | | NAD-dependent protein deacetylase | 0.44 | LRK54_RS10325 | | 3-isopropylmalate dehydrogenase | 0.22 | 13 |
| Paraburkholderia sabiae LMG 24235 | 0.21 | QEN71_RS20510 | | NAD-dependent protein deacetylase | 0.62 | QEN71_RS17620 | | 3-isopropylmalate dehydrogenase | low | > 153 |
| Bifidobacterium breve UCC2003 | 0.21 | BBR_RS20125 | | SIR2 family protein | 0.26 | BBR_RS12870 | | 3-isopropylmalate dehydrogenase | low | > 34 |
| Pseudomonas fluorescens FW300-N2E3 | 0.20 | AO353_26795 | | NAD-dependent deacetylase | 0.88 | AO353_20635 | | 3-isopropylmalate dehydrogenase | low | > 101 |
Not shown: 1 genomes with orthologs for Psest_2405 only; 28 genomes with orthologs for Psest_2589 only