Conservation of cofitness between CSW01_10570 and CSW01_13860 in Vibrio cholerae E7946 ATCC 55056

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_10570 50S ribosomal protein L3 N(5)-glutamine methyltransferase 1.0 CSW01_13860 nitrogen regulation protein NR(II) 0.47 19
Rahnella sp. WP5 0.78 EX31_RS19690 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.55 EX31_RS15875 nitrogen regulation protein NR(II) low > 89
Dickeya dadantii 3937 0.77 DDA3937_RS14585 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.53 DDA3937_RS00130 nitrogen regulation protein NR(II) low > 74
Dickeya dianthicola 67-19 0.77 HGI48_RS14535 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.52 HGI48_RS21230 nitrogen regulation protein NR(II) low > 71
Dickeya dianthicola ME23 0.77 DZA65_RS15470 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.52 DZA65_RS22205 nitrogen regulation protein NR(II) low > 75
Serratia liquefaciens MT49 0.77 IAI46_18030 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.55 IAI46_24955 nitrogen regulation protein NR(II) low > 86
Pectobacterium carotovorum WPP14 0.77 HER17_RS06930 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.51 HER17_RS21435 nitrogen regulation protein NR(II) low > 75
Escherichia fergusonii Becca 0.76 EFB2_01528 50S ribosomal protein L3 glutamine methyltransferase 0.55 EFB2_04747 Sensory histidine kinase/phosphatase NtrB low > 86
Escherichia coli BW25113 0.76 b2330 yfcB putative adenine-specific methylase (VIMSS) 0.55 b3869 glnL sensory histidine kinase in two-component regulatory system with GlnG (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.76 OHPLBJKB_01375 50S ribosomal protein L3 glutamine methyltransferase 0.55 OHPLBJKB_04183 Sensory histidine kinase/phosphatase NtrB low > 74
Klebsiella pneumoniae MKP103 0.76 KDGMDA_27275 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.54 KDGMDA_09005 nitrogen regulation protein NR(II) low > 95
Escherichia coli BL21 0.76 ECD_02255 N5-glutamine methyltransferase 0.55 ECD_03754 sensory histidine kinase in two-component regulatory system with GlnG low > 61
Pantoea sp. MT58 0.76 IAI47_06145 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.54 IAI47_00455 nitrogen regulation protein NR(II) low > 76
Escherichia coli Nissle 1917 0.76 ECOLIN_RS13495 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.55 ECOLIN_RS22300 nitrogen regulation protein NR(II) low > 55
Klebsiella michiganensis M5al 0.76 BWI76_RS20440 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.54 BWI76_RS00390 two-component system sensor histidine kinase NtrB low > 92
Escherichia coli ECOR38 0.76 HEPCGN_21815 prmB 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.55 HEPCGN_12735 glnL nitrogen regulation protein NR(II) low > 88
Enterobacter sp. TBS_079 0.76 MPMX20_03265 50S ribosomal protein L3 glutamine methyltransferase 0.54 MPMX20_04596 Sensory histidine kinase/phosphatase NtrB 0.26 4
Enterobacter asburiae PDN3 0.76 EX28DRAFT_0274 protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 0.54 EX28DRAFT_4351 Signal transduction histidine kinase, nitrogen specific low > 76
Escherichia coli ECRC62 0.76 BNILDI_13165 prmB 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.55 BNILDI_05295 glnL nitrogen regulation protein NR(II) low > 75
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.76 GFF1951 Protein-N(5)-glutamine methyltransferase PrmB, methylates LSU ribosomal protein L3p 0.55 GFF2221 Nitrogen regulation protein NtrB (EC 2.7.13.3) low > 78
Escherichia coli ECRC102 0.76 NIAGMN_20385 prmB 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.55 NIAGMN_11860 glnL nitrogen regulation protein NR(II) low > 80
Pantoea agglomerans CFBP13505 P0401 0.76 PagCFBP13505_RS00100 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.54 PagCFBP13505_RS18890 nitrogen regulation protein NR(II) low > 74
Escherichia coli ECRC100 0.76 OKFHMN_22610 prmB 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.55 OKFHMN_14105 glnL nitrogen regulation protein NR(II) low > 79
Escherichia coli ECRC101 0.76 MCAODC_13650 prmB 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.55 MCAODC_04605 glnL nitrogen regulation protein NR(II) low > 88
Escherichia coli ECRC98 0.76 JDDGAC_26570 prmB 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.55 JDDGAC_17730 glnL nitrogen regulation protein NR(II) low > 87
Escherichia coli ECOR27 0.76 NOLOHH_14245 prmB 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.55 NOLOHH_06235 glnL nitrogen regulation protein NR(II) low > 76
Escherichia coli ECRC99 0.76 KEDOAH_05585 prmB 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.55 KEDOAH_14045 glnL nitrogen regulation protein NR(II)
Erwinia tracheiphila HP pepo 2.2 0.76 IJEDHG_17820 prmB 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.54 IJEDHG_08290 glnL nitrogen regulation protein NR(II) low > 61
Erwinia tracheiphila SCR3 0.75 LU632_RS07770 prmB 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.54 LU632_RS22140 glnL nitrogen regulation protein NR(II) 0.83 1
Erwinia amylovora T8 0.74 OLJFJH_11150 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.54 OLJFJH_05500 nitrogen regulation protein NR(II) low > 58
Shewanella amazonensis SB2B 0.65 Sama_2160 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase (RefSeq) 0.44 Sama_3426 nitrogen regulation protein (RefSeq) low > 62
Shewanella loihica PV-4 0.65 Shew_2417 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase (RefSeq) 0.44 Shew_3560 signal transduction histidine kinase, nitrogen specific, NtrB (RefSeq) low > 60
Shewanella sp. ANA-3 0.64 Shewana3_1468 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase (RefSeq) 0.47 Shewana3_0259 signal transduction histidine kinase, nitrogen specific, NtrB (RefSeq) low > 73
Shewanella oneidensis MR-1 0.62 SO3080 hemK family protein (NCBI ptt file) 0.47 SO4471 ntrB nitrogen regulation protein (NCBI ptt file) low > 76
Alteromonas macleodii MIT1002 0.58 MIT1002_01228 50S ribosomal protein L3 glutamine methyltransferase 0.43 MIT1002_03185 Nitrogen regulation protein NR(II) low > 70
Pseudomonas sp. RS175 0.56 PFR28_03129 50S ribosomal protein L3 glutamine methyltransferase 0.45 PFR28_04945 Sensory histidine kinase/phosphatase NtrB low > 88
Pseudomonas fluorescens FW300-N2C3 0.56 AO356_19525 protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 0.45 AO356_09725 histidine kinase low > 104
Pseudomonas fluorescens FW300-N2E2 0.56 Pf6N2E2_5819 Protein-N(5)-glutamine methyltransferase PrmB, methylates LSU ribosomal protein L3p 0.45 Pf6N2E2_3825 Nitrogen regulation protein NtrB (EC 2.7.13.3) low > 103
Pseudomonas fluorescens FW300-N1B4 0.56 Pf1N1B4_3777 Protein-N(5)-glutamine methyltransferase PrmB, methylates LSU ribosomal protein L3p 0.45 Pf1N1B4_1610 Nitrogen regulation protein NtrB (EC 2.7.13.3) low > 87
Pseudomonas putida KT2440 0.56 PP_1827 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 0.44 PP_5047 two-component system sensory histidine kinase/phosphatase GlnL/GlnG low > 96
Pseudomonas sp. S08-1 0.55 OH686_00665 protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 0.44 OH686_10635 Nitrogen regulation protein NtrB low > 80
Pseudomonas sp. BP01 0.55 JOY50_RS15810 prmB 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.45 JOY50_RS09455 glnL nitrogen regulation protein NR(II) low > 84
Pseudomonas fluorescens FW300-N2E3 0.55 AO353_02265 protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 0.44 AO353_12150 histidine kinase low > 101
Pseudomonas fluorescens GW456-L13 0.55 PfGW456L13_4168 Protein-N(5)-glutamine methyltransferase PrmB, methylates LSU ribosomal protein L3p 0.44 PfGW456L13_346 Nitrogen regulation protein NtrB (EC 2.7.13.3) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.55 Psyr_1850 [LSU ribosomal protein L3P]-glutamine N5-methyltransferase 0.45 Psyr_4821 PAS/PAC sensor signal transduction histidine kinase low > 86
Pseudomonas sp. DMC3 0.55 GFF2628 50S ribosomal protein L3 glutamine methyltransferase 0.45 GFF4080 Sensory histidine kinase/phosphatase NtrB low > 89
Pseudomonas syringae pv. syringae B728a 0.55 Psyr_1850 [LSU ribosomal protein L3P]-glutamine N5-methyltransferase 0.45 Psyr_4821 PAS/PAC sensor signal transduction histidine kinase low > 86
Pseudomonas aeruginosa PA14 0.55 IKLFDK_08085 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.44 IKLFDK_27900 two-component system sensor histidine kinase NtrB low > 100
Pseudomonas lactucae CFBP13502 0.55 GEMAOFIL_04068 50S ribosomal protein L3 glutamine methyltransferase 0.44 GEMAOFIL_00548 Sensory histidine kinase/phosphatase NtrB low > 93
Pseudomonas fluorescens SBW25 0.55 PFLU_RS21295 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.44 PFLU_RS01690 nitrogen regulation protein NR(II) low > 109
Pseudomonas segetis P6 0.55 MPMX49_02188 50S ribosomal protein L3 glutamine methyltransferase 0.44 MPMX49_04286 Sensory histidine kinase/phosphatase NtrB low > 75
Pseudomonas fluorescens SBW25-INTG 0.55 PFLU_RS21295 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.44 PFLU_RS01690 nitrogen regulation protein NR(II) low > 109
Pseudomonas stutzeri RCH2 0.54 Psest_1995 protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 0.43 Psest_3931 Signal transduction histidine kinase, nitrogen specific low > 67
Pseudomonas sp. SVBP6 0.54 COO64_RS06255 prmB 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.44 COO64_RS13330 glnL nitrogen regulation protein NR(II) low > 93
Pseudomonas simiae WCS417 0.54 PS417_19330 SAM-dependent methyltransferase 0.45 PS417_01640 histidine kinase
Marinobacter adhaerens HP15 0.54 HP15_1839 protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 0.43 HP15_426 signal transduction histidine kinase, nitrogen specific, NtrB low > 73
Kangiella aquimarina DSM 16071 0.50 B158DRAFT_1297 [LSU ribosomal protein L3P]-glutamine N5-methyltransferase (EC 2.1.1.-) 0.26 B158DRAFT_0715 Signal transduction histidine kinase, nitrogen specific low > 40
Acinetobacter radioresistens SK82 0.46 MPMX26_01339 50S ribosomal protein L3 glutamine methyltransferase 0.34 MPMX26_01293 Sensory histidine kinase/phosphatase NtrB low > 36
Dechlorosoma suillum PS 0.45 Dsui_2712 protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 0.40 Dsui_1050 signal transduction histidine kinase, nitrogen specific low > 51
Azospirillum brasilense Sp245 0.45 AZOBR_RS10950 SAM-dependent methyltransferase 0.23 AZOBR_RS14425 ATPase low > 97
Acinetobacter baumannii LAC-4 0.44 RR41_RS12710 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.34 RR41_RS08035 PAS domain-containing protein
Rhodanobacter sp000427505 FW510-R12 0.44 LRK53_RS08300 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.24 LRK53_RS00565 ATP-binding protein low > 59
Castellaniella sp019104865 MT123 0.44 ABCV34_RS05175 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.30 ABCV34_RS03535 nitrogen regulation protein NR(II) low > 48
Methylophilus sp. DMC18 0.44 GFF893 50S ribosomal protein L3 glutamine methyltransferase 0.37 GFF2023 Sensory histidine kinase/phosphatase NtrB low > 43
Azospirillum sp. SherDot2 0.44 MPMX19_00751 50S ribosomal protein L3 glutamine methyltransferase 0.23 MPMX19_01111 Sensory histidine kinase/phosphatase NtrB low > 112
Rhodanobacter sp. FW510-T8 0.44 OKGIIK_04795 prmB 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.22 OKGIIK_14470 PAS domain-containing sensor histidine kinase low > 53
Rhodanobacter denitrificans MT42 0.44 LRK55_RS01515 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.21 LRK55_RS07735 ATP-binding protein low > 63
Rhodanobacter denitrificans FW104-10B01 0.44 LRK54_RS01735 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.21 LRK54_RS07985 ATP-binding protein low > 59
Paraburkholderia sabiae LMG 24235 0.42 QEN71_RS06350 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.31 QEN71_RS05670 nitrogen regulation protein NR(II) low > 153
Ralstonia solanacearum GMI1000 0.42 RS_RS06960 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.32 RS_RS06315 PAS domain-containing sensor histidine kinase low > 80
Paraburkholderia graminis OAS925 0.42 ABIE53_002520 ribosomal protein L3 glutamine methyltransferase 0.31 ABIE53_002805 two-component system nitrogen regulation sensor histidine kinase GlnL low > 113
Ralstonia solanacearum PSI07 0.42 RPSI07_RS17185 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.31 RPSI07_RS17820 PAS domain-containing sensor histidine kinase low > 81
Ralstonia solanacearum IBSBF1503 0.42 RALBFv3_RS00290 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.31 RALBFv3_RS15535 PAS domain-containing sensor histidine kinase
Ralstonia solanacearum UW163 0.42 UW163_RS13620 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.31 UW163_RS12995 PAS domain-containing sensor histidine kinase
Ralstonia sp. UNC404CL21Col 0.41 ABZR87_RS11740 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.30 ABZR87_RS11065 nitrogen regulation protein NR(II) low > 80
Herbaspirillum seropedicae SmR1 0.41 HSERO_RS10785 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 0.36 HSERO_RS15685 histidine kinase low > 78
Paraburkholderia bryophila 376MFSha3.1 0.39 H281DRAFT_00596 [LSU ribosomal protein L3P]-glutamine N5-methyltransferase 0.31 H281DRAFT_00453 two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL low > 103
Burkholderia phytofirmans PsJN 0.39 BPHYT_RS12205 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 0.31 BPHYT_RS12940 signal transduction histidine kinase low > 109
Cupriavidus basilensis FW507-4G11 0.38 RR42_RS11955 SAM-dependent methyltransferase 0.33 RR42_RS12985 histidine kinase low > 128
Rhodopseudomonas palustris CGA009 0.38 TX73_005990 50S ribosomal protein L3 N(5)-glutamine methyltransferase 0.24 TX73_013415 nitrogen regulation protein NR(II) low > 86
Hydrogenophaga sp. GW460-11-11-14-LB1 0.33 GFF4549 Protein-N(5)-glutamine methyltransferase PrmB, methylates LSU ribosomal protein L3p 0.30 GFF5270 Nitrogen regulation protein NtrB (EC 2.7.13.3) low > 90

Not shown: 6 genomes with orthologs for CSW01_10570 only; 11 genomes with orthologs for CSW01_13860 only