Conservation of cofitness between BWI76_RS00140 and BWI76_RS20640 in Klebsiella michiganensis M5al

76 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS00140 phosphate transport system regulator PhoU 1.0 BWI76_RS20640 cysteine synthase A 0.35 13
Enterobacter sp. TBS_079 0.99 MPMX20_04643 Phosphate-specific transport system accessory protein PhoU 0.93 MPMX20_03308 Cysteine synthase A
Enterobacter asburiae PDN3 0.99 EX28DRAFT_4000 phosphate transport system regulatory protein PhoU 0.94 EX28DRAFT_0214 cysteine synthase A
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.98 GFF1738 Phosphate transport system regulatory protein PhoU 0.94 GFF2044 Cysteine synthase (EC 2.5.1.47)
Escherichia coli ECOR38 0.96 HEPCGN_13610 phoU phosphate signaling complex protein PhoU 0.93 HEPCGN_21380 cysK cysteine synthase A
Escherichia coli ECRC99 0.96 KEDOAH_13250 phoU phosphate signaling complex protein PhoU 0.94 KEDOAH_06020 cysK cysteine synthase A
Escherichia coli ECRC98 0.96 JDDGAC_18520 phoU phosphate signaling complex protein PhoU 0.94 JDDGAC_26150 cysK cysteine synthase A
Escherichia coli ECRC100 0.96 OKFHMN_14900 phoU phosphate signaling complex protein PhoU 0.94 OKFHMN_22200 cysK cysteine synthase A
Escherichia coli ECRC101 0.96 MCAODC_05405 phoU phosphate signaling complex protein PhoU 0.94 MCAODC_12730 cysK cysteine synthase A
Escherichia coli ECRC102 0.96 NIAGMN_12655 phoU phosphate signaling complex protein PhoU 0.94 NIAGMN_19970 cysK cysteine synthase A
Escherichia coli HS(pFamp)R (ATCC 700891) 0.95 OHPLBJKB_04329 Phosphate-specific transport system accessory protein PhoU 0.94 OHPLBJKB_01309 Cysteine synthase A
Escherichia coli BL21 0.95 ECD_03608 negative regulator of PhoR/PhoB two-component regulator 0.94 ECD_02314 cysteine synthase A, O-acetylserine sulfhydrolase A subunit
Escherichia coli BW25113 0.95 b3724 phoU negative regulator of PhoR/PhoB two-component regulator (NCBI) 0.94 b2414 cysK cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI)
Escherichia coli ECOR27 0.95 NOLOHH_07030 pstA phosphate ABC transporter permease PstA 0.94 NOLOHH_13880 cysK cysteine synthase A
Escherichia coli ECRC62 0.95 BNILDI_04495 pstA phosphate ABC transporter permease PstA 0.94 BNILDI_12745 cysK cysteine synthase A
Escherichia fergusonii Becca 0.94 EFB2_04909 Phosphate-specific transport system accessory protein PhoU 0.94 EFB2_01462 Cysteine synthase A
Escherichia coli Nissle 1917 0.94 ECOLIN_RS21430 phosphate signaling complex protein PhoU 0.94 ECOLIN_RS13870 cysteine synthase A
Serratia liquefaciens MT49 0.93 IAI46_25195 phosphate signaling complex protein PhoU 0.82 IAI46_18445 cysteine synthase A low > 86
Pectobacterium carotovorum WPP14 0.92 HER17_RS21695 phosphate signaling complex protein PhoU 0.84 HER17_RS17170 cysteine synthase A
Rahnella sp. WP5 0.92 EX31_RS06050 phosphate signaling complex protein PhoU 0.80 EX31_RS20175 cysteine synthase A
Dickeya dianthicola ME23 0.90 DZA65_RS22560 phosphate signaling complex protein PhoU 0.84 DZA65_RS04370 cysteine synthase A
Dickeya dianthicola 67-19 0.90 HGI48_RS21580 phosphate signaling complex protein PhoU 0.84 HGI48_RS04450 cysteine synthase A
Dickeya dadantii 3937 0.90 DDA3937_RS21450 phosphate signaling complex protein PhoU 0.85 DDA3937_RS04490 cysteine synthase A
Pantoea sp. MT58 0.88 IAI47_00215 phosphate signaling complex protein PhoU 0.90 IAI47_05440 cysteine synthase A
Erwinia tracheiphila SCR3 0.87 LU632_RS24900 phoU phosphate signaling complex protein PhoU 0.87 LU632_RS06625 cysK cysteine synthase A
Shewanella amazonensis SB2B 0.65 Sama_1411 transcriptional regulator PhoU (RefSeq) 0.71 Sama_1508 cysteine synthase A (RefSeq)
Shewanella sp. ANA-3 0.64 Shewana3_2731 transcriptional regulator PhoU (RefSeq) 0.73 Shewana3_1561 cysteine synthase (RefSeq)
Shewanella loihica PV-4 0.64 Shew_1701 transcriptional regulator PhoU (RefSeq) 0.70 Shew_2382 cysteine synthase A (RefSeq)
Shewanella oneidensis MR-1 0.63 SO1726 phoU phosphate transport system regulatory protein PhoU (NCBI ptt file) 0.73 SO2903 cysK cysteine synthase A (NCBI ptt file)
Vibrio cholerae E7946 ATCC 55056 0.61 CSW01_03800 phosphate transport system regulator PhoU 0.78 CSW01_04945 cysteine synthase A
Pseudomonas stutzeri RCH2 0.45 Psest_0223 phosphate transport system regulatory protein PhoU 0.64 Psest_1855 cysteine synthase A
Pseudomonas putida KT2440 0.45 PP_5325 phosphate transport-associated protein 0.65 PP_4571 cysteine synthase A
Pseudomonas fluorescens FW300-N2C3 0.45 AO356_11025 transcriptional regulator PhoU 0.67 AO356_04305 cysteine synthase low > 104
Pseudomonas fluorescens FW300-N2E2 0.45 Pf6N2E2_4071 Phosphate transport system regulatory protein PhoU 0.67 Pf6N2E2_2700 Cysteine synthase (EC 2.5.1.47) low > 103
Pseudomonas sp. RS175 0.45 PFR28_04485 Phosphate-specific transport system accessory protein PhoU 0.67 PFR28_00734 Cysteine synthase A low > 88
Pseudomonas fluorescens FW300-N1B4 0.45 Pf1N1B4_2038 Phosphate transport system regulatory protein PhoU 0.66 Pf1N1B4_3374 Cysteine synthase (EC 2.5.1.47)
Pseudomonas fluorescens SBW25 0.44 PFLU_RS29750 phosphate signaling complex protein PhoU 0.65 PFLU_RS07585 cysteine synthase A low > 109
Pseudomonas fluorescens GW456-L13 0.44 PfGW456L13_757 Phosphate transport system regulatory protein PhoU 0.66 PfGW456L13_4472 Cysteine synthase (EC 2.5.1.47) low > 87
Pseudomonas fluorescens SBW25-INTG 0.44 PFLU_RS29750 phosphate signaling complex protein PhoU 0.65 PFLU_RS07585 cysteine synthase A low > 109
Pseudomonas simiae WCS417 0.44 PS417_28065 transcriptional regulator PhoU 0.66 PS417_07505 cysteine synthase
Pseudomonas sp. S08-1 0.44 OH686_13430 phosphate transport system regulatory protein PhoU 0.66 OH686_05215 cysteine synthase A low > 80
Pseudomonas fluorescens FW300-N2E3 0.44 AO353_09885 transcriptional regulator PhoU 0.67 AO353_18020 cysteine synthase low > 101
Pseudomonas syringae pv. syringae B728a ΔmexB 0.43 Psyr_5037 phosphate uptake regulator, PhoU 0.65 Psyr_1583 cysteine synthase
Pseudomonas syringae pv. syringae B728a 0.43 Psyr_5037 phosphate uptake regulator, PhoU 0.65 Psyr_1583 cysteine synthase
Marinobacter adhaerens HP15 0.43 HP15_3385 phosphate uptake regulator, PhoU 0.69 HP15_3453 cysteine synthase A
Dechlorosoma suillum PS 0.43 Dsui_1573 phosphate transport system regulatory protein PhoU 0.61 Dsui_2521 cysteine synthase A
Cupriavidus basilensis FW507-4G11 0.41 RR42_RS13450 PhoU family transcriptional regulator 0.36 RR42_RS21960 cysteine synthase low > 128
Variovorax sp. SCN45 0.41 GFF1096 Phosphate transport system regulatory protein PhoU 0.41 GFF4549 Cysteine synthase (EC 2.5.1.47) low > 127
Variovorax sp. OAS795 0.40 ABID97_RS14615 phosphate signaling complex protein PhoU 0.40 ABID97_RS06080 cysteine synthase A low > 91
Alteromonas macleodii MIT1002 0.40 MIT1002_00877 Repressor protein PhoU 0.71 MIT1002_02237 Cysteine synthase A
Acidovorax sp. GW101-3H11 0.39 Ac3H11_460 Phosphate transport system regulatory protein PhoU 0.38 Ac3H11_1975 Cysteine synthase (EC 2.5.1.47) low > 79
Hydrogenophaga sp. GW460-11-11-14-LB1 0.37 GFF4234 Phosphate transport system regulatory protein PhoU 0.40 GFF4578 Cysteine synthase (EC 2.5.1.47) low > 90
Brevundimonas sp. GW460-12-10-14-LB2 0.34 A4249_RS08975 phosphate signaling complex protein PhoU 0.44 A4249_RS10255 cysteine synthase A
Rhodospirillum rubrum S1H 0.33 Rru_A0602 Phosphate uptake regulator, PhoU (NCBI) 0.49 Rru_A3794 Cysteine synthase (NCBI)
Bosea sp. OAE506 0.33 ABIE41_RS08905 phosphate signaling complex protein PhoU 0.43 ABIE41_RS03545 cysteine synthase A low > 77
Dinoroseobacter shibae DFL-12 0.32 Dshi_1537 phosphate uptake regulator, PhoU (RefSeq) 0.28 Dshi_0891 cysteine synthase A (RefSeq) low > 64
Sphingomonas koreensis DSMZ 15582 0.31 Ga0059261_3652 phosphate transport system regulatory protein PhoU 0.38 Ga0059261_3644 cysteine synthase A low > 68
Sinorhizobium meliloti 1021 0.31 SMc02141 phosphate transporter PhoU 0.45 SMc00421 O-acetylserine sulfhydrylase A low > 103
Caulobacter crescentus NA1000 Δfur 0.31 CCNA_00295 phosphate transport system protein phoU 0.42 CCNA_03740 cysteine synthase
Caulobacter crescentus NA1000 0.31 CCNA_00295 phosphate transport system protein phoU 0.42 CCNA_03740 cysteine synthase
Rhizobium sp. OAE497 0.30 ABIE40_RS02305 phosphate signaling complex protein PhoU 0.46 ABIE40_RS01415 cysteine synthase A low > 107
Rhodopseudomonas palustris CGA009 0.30 TX73_024825 phosphate signaling complex protein PhoU 0.44 TX73_002885 cysteine synthase A
Magnetospirillum magneticum AMB-1 0.29 AMB_RS06940 phosphate transport system regulatory protein PhoU 0.43 AMB_RS01005 cysteine synthase A
Agrobacterium fabrum C58 0.29 Atu0424 phosphate transport system regulatory protein 0.44 Atu0312 cysteine synthase
Azospirillum brasilense Sp245 0.29 AZOBR_RS08185 PhoU family transcriptional regulator 0.46 AZOBR_RS01080 cysteine synthase
Azospirillum sp. SherDot2 0.29 MPMX19_01281 Phosphate-specific transport system accessory protein PhoU 0.44 MPMX19_00237 Cysteine synthase low > 112
Desulfovibrio vulgaris Miyazaki F 0.26 DvMF_0880 phosphate uptake regulator, PhoU (RefSeq) 0.43 DvMF_2658 cysteine synthase (RefSeq)
Desulfovibrio vulgaris Hildenborough JW710 0.24 DVU1085 phoU phosphate transport system protein PhoU (TIGR) 0.46 DVU0663 cysK cysteine synthase A (TIGR)
Pontibacter actiniarum KMM 6156, DSM 19842 0.21 CA264_18725 phosphate transport system regulatory protein PhoU 0.39 CA264_13470 cysteine synthase A low > 74
Parabacteroides merdae CL09T00C40 0.21 HMPREF1078_RS17190 phosphate signaling complex protein PhoU 0.47 HMPREF1078_RS08075 cysteine synthase A
Bacteroides stercoris CC31F 0.18 HMPREF1181_RS10820 phosphate signaling complex protein PhoU 0.50 HMPREF1181_RS01560 cysteine synthase A low > 56
Bacteroides ovatus ATCC 8483 0.17 BACOVA_00605 phosphate transport system regulatory protein PhoU 0.47 BACOVA_02771 cysteine synthase A 0.38 15
Phocaeicola dorei CL03T12C01 0.17 ABI39_RS20360 phosphate signaling complex protein PhoU 0.47 ABI39_RS02185 cysteine synthase A low > 72
Bacteroides thetaiotaomicron VPI-5482 0.17 BT1320 putative transcriptional regulator, phosphate uptake regulation (NCBI ptt file) 0.51 BT3080 cysteine synthase A (NCBI ptt file) low > 81
Phocaeicola vulgatus CL09T03C04 0.17 HMPREF1058_RS06565 phosphate signaling complex protein PhoU 0.48 HMPREF1058_RS02875 cysteine synthase A low > 67
Synechococcus elongatus PCC 7942 0.12 Synpcc7942_1912 phoU phosphate uptake regulator, PhoU 0.65 Synpcc7942_B2664 srpG cysteine synthase
Mycobacterium tuberculosis H37Rv 0.12 Rv0821c Probable phosphate-transport system transcriptional regulatory protein PhoY2 0.47 Rv2334 Cysteine synthase a CysK1 (O-acetylserine sulfhydrylase A) (O-acetylserine (thiol)-lyase A) (CSASE A)

Not shown: 23 genomes with orthologs for BWI76_RS00140 only; 1 genomes with orthologs for BWI76_RS20640 only