Conservation of cofitness between BWI76_RS08740 and BWI76_RS08720 in Klebsiella michiganensis M5al

68 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS08740 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 1.0 BWI76_RS08720 imidazolonepropionase 0.20 9
Enterobacter sp. TBS_079 0.87 MPMX20_01400 Histidine ammonia-lyase 0.72 MPMX20_01396 Imidazolonepropionase 0.55 2
Enterobacter asburiae PDN3 0.86 EX28DRAFT_2219 histidine ammonia-lyase (EC 4.3.1.3) 0.73 EX28DRAFT_2223 imidazolonepropionase (EC 3.5.2.7) low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.83 GFF668 Histidine ammonia-lyase (EC 4.3.1.3) 0.71 GFF663 Imidazolonepropionase (EC 3.5.2.7) low > 78
Pseudomonas simiae WCS417 0.80 PS417_01750 histidine ammonia-lyase 0.50 PS417_01760 imidazolonepropionase 0.44 3
Pseudomonas fluorescens SBW25 0.79 PFLU_RS01805 histidine ammonia-lyase 0.50 PFLU_RS01815 imidazolonepropionase low > 109
Pseudomonas fluorescens SBW25-INTG 0.79 PFLU_RS01805 histidine ammonia-lyase 0.50 PFLU_RS01815 imidazolonepropionase 0.17 91
Pseudomonas fluorescens GW456-L13 0.79 PfGW456L13_320 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 0.53 PfGW456L13_317 Imidazolonepropionase (EC 3.5.2.7) (from data) 0.88 3
Pseudomonas putida KT2440 0.79 PP_5032 Histidine ammonia-lyase 0.51 PP_5030 Imidazolonepropionase 0.41 4
Serratia liquefaciens MT49 0.79 IAI46_03660 histidine ammonia-lyase 0.46 IAI46_10610 imidazolonepropionase low > 86
Pseudomonas fluorescens FW300-N1B4 0.79 Pf1N1B4_1581 Histidine ammonia-lyase (EC 4.3.1.3) 0.52 Pf1N1B4_1579 Imidazolonepropionase (EC 3.5.2.7) (from data) 0.39 4
Pseudomonas fluorescens FW300-N2E2 0.79 Pf6N2E2_3799 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 0.52 Pf6N2E2_3798 Imidazolonepropionase (EC 3.5.2.7) (from data) 0.78 3
Pseudomonas sp. RS175 0.79 PFR28_04971 Histidine ammonia-lyase 0.50 PFR28_04972 Imidazolonepropionase low > 88
Pseudomonas fluorescens FW300-N2C3 0.78 AO356_09600 histidine ammonia-lyase 0.50 AO356_09595 Imidazolonepropionase (EC 3.5.2.7) (from data) 0.80 1
Pseudomonas syringae pv. syringae B728a ΔmexB 0.78 Psyr_4833 histidine ammonia-lyase 0.51 Psyr_4835 imidazolonepropionase low > 86
Pseudomonas syringae pv. syringae B728a 0.78 Psyr_4833 histidine ammonia-lyase 0.51 Psyr_4835 imidazolonepropionase low > 86
Pseudomonas fluorescens FW300-N2E3 0.78 AO353_12270 histidine ammonia-lyase 0.50 AO353_12280 Imidazolonepropionase (EC 3.5.2.7) (from data) 0.61 1
Pseudomonas sp. S08-1 0.78 OH686_16755 histidine ammonia-lyase 0.46 OH686_16735 imidazolonepropionase low > 80
Cupriavidus basilensis FW507-4G11 0.78 RR42_RS14640 histidine ammonia-lyase 0.47 RR42_RS16905 Imidazolonepropionase (EC 3.5.2.7) (from data) low > 128
Vibrio cholerae E7946 ATCC 55056 0.70 CSW01_06080 histidine ammonia-lyase 0.52 CSW01_06095 imidazolonepropionase low > 62
Shewanella oneidensis MR-1 0.66 SO0098 hutH histidine ammonia-lyase (NCBI ptt file) 0.50 SO0095 hutI Imidazolonepropionase (EC 3.5.2.7) (from data) 0.27 40
Shewanella sp. ANA-3 0.66 Shewana3_0101 histidine ammonia-lyase (RefSeq) 0.50 Shewana3_0098 imidazolonepropionase (RefSeq) low > 73
Shewanella loihica PV-4 0.66 Shew_3756 histidine ammonia-lyase (RefSeq) 0.50 Shew_3759 imidazolonepropionase (RefSeq) low > 60
Alteromonas macleodii MIT1002 0.62 MIT1002_00905 Histidine ammonia-lyase 0.45 MIT1002_00902 Imidazolonepropionase low > 70
Paraburkholderia sabiae LMG 24235 0.59 QEN71_RS23515 histidine ammonia-lyase 0.49 QEN71_RS23495 imidazolonepropionase 0.72 3
Kangiella aquimarina DSM 16071 0.58 B158DRAFT_1432 histidine ammonia-lyase (EC 4.3.1.3) 0.49 B158DRAFT_1437 imidazolonepropionase (EC 3.5.2.7) low > 40
Ralstonia solanacearum UW163 0.57 UW163_RS08235 histidine ammonia-lyase 0.48 UW163_RS08245 imidazolonepropionase — —
Ralstonia solanacearum PSI07 0.57 RPSI07_RS11915 histidine ammonia-lyase 0.49 RPSI07_RS11925 imidazolonepropionase low > 81
Ralstonia solanacearum GMI1000 0.57 RS_RS13250 histidine ammonia-lyase 0.49 RS_RS13240 imidazolonepropionase low > 80
Ralstonia solanacearum IBSBF1503 0.57 RALBFv3_RS05390 histidine ammonia-lyase 0.48 RALBFv3_RS05380 imidazolonepropionase low > 76
Ralstonia sp. UNC404CL21Col 0.57 ABZR87_RS01025 histidine ammonia-lyase 0.49 ABZR87_RS01015 imidazolonepropionase low > 80
Paraburkholderia bryophila 376MFSha3.1 0.57 H281DRAFT_04873 histidine ammonia-lyase 0.46 H281DRAFT_04869 imidazolonepropionase low > 103
Burkholderia phytofirmans PsJN 0.57 BPHYT_RS07555 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 0.48 BPHYT_RS07575 imidazolonepropionase 0.40 5
Rahnella sp. WP5 0.55 EX31_RS06755 histidine ammonia-lyase 0.49 EX31_RS06720 imidazolonepropionase low > 89
Hydrogenophaga sp. GW460-11-11-14-LB1 0.55 GFF3589 Histidine ammonia-lyase (EC 4.3.1.3) 0.51 GFF3588 Imidazolonepropionase (EC 3.5.2.7) — —
Dickeya dadantii 3937 0.54 DDA3937_RS14995 histidine ammonia-lyase 0.46 DDA3937_RS15060 imidazolonepropionase low > 74
Variovorax sp. OAS795 0.54 ABID97_RS03420 histidine ammonia-lyase 0.46 ABID97_RS03435 imidazolonepropionase 0.89 1
Pantoea sp. MT58 0.54 IAI47_13275 histidine ammonia-lyase 0.48 IAI47_13255 imidazolonepropionase low > 76
Variovorax sp. SCN45 0.53 GFF6409 Histidine ammonia-lyase (EC 4.3.1.3) 0.46 GFF6402 Imidazolonepropionase (EC 3.5.2.7) low > 127
Dickeya dianthicola 67-19 0.53 HGI48_RS15090 histidine ammonia-lyase 0.47 HGI48_RS15140 imidazolonepropionase low > 71
Acidovorax sp. GW101-3H11 0.53 Ac3H11_2558 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 0.44 Ac3H11_2550 Imidazolonepropionase (EC 3.5.2.7) (from data) 0.81 6
Rhodospirillum rubrum S1H 0.53 Rru_A1301 Histidine ammonia-lyase (NCBI) 0.44 Rru_A1303 Imidazolonepropionase (NCBI) low > 58
Castellaniella sp019104865 MT123 0.53 ABCV34_RS12780 histidine ammonia-lyase 0.46 ABCV34_RS12775 imidazolonepropionase low > 48
Dickeya dianthicola ME23 0.53 DZA65_RS15835 histidine ammonia-lyase 0.46 DZA65_RS15940 imidazolonepropionase low > 75
Azospirillum sp. SherDot2 0.52 MPMX19_04940 Histidine ammonia-lyase 0.49 MPMX19_04938 Imidazolonepropionase 0.56 68
Brevundimonas sp. GW460-12-10-14-LB2 0.51 A4249_RS06630 histidine ammonia-lyase 0.44 A4249_RS06605 imidazolonepropionase low > 48
Caulobacter crescentus NA1000 0.50 CCNA_01010 histidine ammonia-lyase 0.47 CCNA_01011 imidazolonepropionase 0.77 1
Caulobacter crescentus NA1000 Δfur 0.50 CCNA_01010 histidine ammonia-lyase 0.47 CCNA_01011 imidazolonepropionase 0.86 5
Sinorhizobium meliloti 1021 0.49 SM_b21165 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 0.40 SM_b21166 Imidazolonepropionase (EC 3.5.2.7) (from data) 0.83 2
Rhizobium sp. OAE497 0.49 ABIE40_RS20355 histidine ammonia-lyase 0.46 ABIE40_RS20350 imidazolonepropionase 0.92 2
Agrobacterium fabrum C58 0.48 Atu3933 histidine ammonia-lyase 0.47 Atu3934 imidazolonepropionase 0.69 1
Sphingomonas koreensis DSMZ 15582 0.48 Ga0059261_3963 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 0.45 Ga0059261_3964 Imidazolonepropionase (EC 3.5.2.7) (from data) 0.86 1
Xanthomonas campestris pv. campestris strain 8004 0.48 Xcc-8004.3296.1 Histidine ammonia-lyase (EC 4.3.1.3) 0.44 Xcc-8004.3295.1 Imidazolonepropionase (EC 3.5.2.7) 0.64 19
Bosea sp. OAE506 0.46 ABIE41_RS23645 histidine ammonia-lyase 0.48 ABIE41_RS23640 imidazolonepropionase 0.71 2
Phaeobacter inhibens DSM 17395 0.45 PGA1_c36340 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 0.46 PGA1_c36350 Imidazolonepropionase (EC 3.5.2.7) (from data) 0.83 2
Fusobacterium nucleatum SB010 0.39 HUW76_04780 histidine ammonia-lyase 0.32 HUW76_04550 imidazolonepropionase low > 35
Shewanella amazonensis SB2B 0.38 Sama_1631 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 0.49 Sama_0080 imidazolonepropionase (RefSeq) 0.60 4
Pontibacter actiniarum KMM 6156, DSM 19842 0.37 CA264_04560 histidine ammonia-lyase 0.23 CA264_08870 imidazolonepropionase 0.60 1
Phocaeicola vulgatus CL09T03C04 0.34 HMPREF1058_RS02545 histidine ammonia-lyase 0.29 HMPREF1058_RS02535 imidazolonepropionase 0.93 4
Bacteroides thetaiotaomicron VPI-5482 0.34 BT2690 histidine ammonia-lyase (NCBI ptt file) 0.26 BT2692 imidazolonepropionase (NCBI ptt file) low > 81
Phocaeicola dorei CL03T12C01 0.34 ABI39_RS01830 histidine ammonia-lyase 0.29 ABI39_RS01820 imidazolonepropionase low > 72
Bacteroides ovatus ATCC 8483 0.33 BACOVA_00991 histidine ammonia-lyase 0.26 BACOVA_00993 imidazolonepropionase 0.63 1
Bacteroides stercoris CC31F 0.32 HMPREF1181_RS00340 histidine ammonia-lyase 0.27 HMPREF1181_RS00350 imidazolonepropionase low > 56
Parabacteroides merdae CL09T00C40 0.32 HMPREF1078_RS11575 histidine ammonia-lyase 0.31 HMPREF1078_RS11585 imidazolonepropionase low > 61
Lysobacter sp. OAE881 0.28 ABIE51_RS13345 aromatic amino acid lyase 0.42 ABIE51_RS06250 imidazolonepropionase low > 62
Rhodanobacter sp. FW510-T8 0.28 OKGIIK_05610 hutH histidine ammonia-lyase 0.47 OKGIIK_08425 hutI imidazolonepropionase low > 52
Rhodanobacter denitrificans FW104-10B01 0.28 LRK54_RS01300 aromatic amino acid ammonia-lyase 0.47 LRK54_RS16230 imidazolonepropionase low > 59
Dyella japonica UNC79MFTsu3.2 0.28 ABZR86_RS06750 histidine ammonia-lyase 0.48 ABZR86_RS07870 imidazolonepropionase low > 74
Escherichia coli ECOR38 0.18 HEPCGN_01360 histidine ammonia-lyase 0.46 HEPCGN_01350 hutI imidazolonepropionase low > 87

Not shown: 6 genomes with orthologs for BWI76_RS08740 only; 2 genomes with orthologs for BWI76_RS08720 only