Conservation of cofitness between ABZR87_RS15265 and ABZR87_RS02545 in Ralstonia sp. UNC404CL21Col

70 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Ralstonia sp. UNC404CL21Col 1.0 ABZR87_RS15265 radical SAM family heme chaperone HemW 1.0 ABZR87_RS02545 outer membrane lipid asymmetry maintenance protein MlaD 0.61 10
Ralstonia solanacearum PSI07 0.94 RPSI07_RS13830 oxygen-independent coproporphyrinogen III oxidase-like protein 0.85 RPSI07_RS10345 outer membrane lipid asymmetry maintenance protein MlaD low > 81
Ralstonia solanacearum UW163 0.90 UW163_RS10365 oxygen-independent coproporphyrinogen III oxidase-like protein 0.84 UW163_RS06725 outer membrane lipid asymmetry maintenance protein MlaD
Ralstonia solanacearum IBSBF1503 0.90 RALBFv3_RS03355 oxygen-independent coproporphyrinogen III oxidase-like protein 0.84 RALBFv3_RS06890 outer membrane lipid asymmetry maintenance protein MlaD low > 76
Ralstonia solanacearum GMI1000 0.89 RS_RS10840 oxygen-independent coproporphyrinogen III oxidase-like protein 0.84 RS_RS14835 outer membrane lipid asymmetry maintenance protein MlaD low > 80
Cupriavidus basilensis FW507-4G11 0.69 RR42_RS04880 coproporphyrinogen III oxidase 0.69 RR42_RS18960 ABC transporter substrate-binding protein low > 128
Paraburkholderia graminis OAS925 0.66 ABIE53_003236 putative oxygen-independent coproporphyrinogen III oxidase 0.69 ABIE53_003710 phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein low > 113
Burkholderia phytofirmans PsJN 0.66 BPHYT_RS15335 coproporphyrinogen III oxidase 0.69 BPHYT_RS17755 ABC transporter substrate-binding protein low > 109
Paraburkholderia bryophila 376MFSha3.1 0.66 H281DRAFT_04010 oxygen-independent coproporphyrinogen-3 oxidase 0.70 H281DRAFT_05643 phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein low > 103
Paraburkholderia sabiae LMG 24235 0.66 QEN71_RS03635 radical SAM family heme chaperone HemW 0.70 QEN71_RS27910 outer membrane lipid asymmetry maintenance protein MlaD low > 153
Herbaspirillum seropedicae SmR1 0.63 HSERO_RS10665 coproporphyrinogen III oxidase 0.66 HSERO_RS20390 ABC transporter substrate-binding protein
Hydrogenophaga sp. GW460-11-11-14-LB1 0.57 GFF3256 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.61 GFF1323 Uncharacterized ABC transporter, periplasmic component YrbD low > 90
Variovorax sp. SCN45 0.56 GFF2383 Oxygen-independent coproporphyrinogen-III oxidase-like protein YggW 0.55 GFF5336 Phospholipid ABC transporter substrate-binding protein MlaD low > 127
Variovorax sp. OAS795 0.55 ABID97_RS23630 radical SAM family heme chaperone HemW 0.60 ABID97_RS23205 outer membrane lipid asymmetry maintenance protein MlaD low > 91
Acidovorax sp. GW101-3H11 0.52 Ac3H11_3672 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.61 Ac3H11_4714 Uncharacterized ABC transporter, periplasmic component YrbD low > 79
Castellaniella sp019104865 MT123 0.52 ABCV34_RS03525 radical SAM family heme chaperone HemW 0.64 ABCV34_RS11190 outer membrane lipid asymmetry maintenance protein MlaD
Dechlorosoma suillum PS 0.52 Dsui_0491 putative oxygen-independent coproporphyrinogen III oxidase 0.59 Dsui_1400 ABC-type transport system involved in resistance to organic solvents, periplasmic component low > 51
Xanthomonas campestris pv. campestris strain 8004 0.45 Xcc-8004.1224.1 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.30 Xcc-8004.5366.1 Uncharacterized ABC transporter, periplasmic component YrbD low > 74
Pseudomonas simiae WCS417 0.45 PS417_26760 oxidase 0.32 PS417_04385 organic solvent ABC transporter substrate-binding protein low > 88
Pseudomonas fluorescens SBW25-INTG 0.45 PFLU_RS28405 radical SAM family heme chaperone HemW 0.32 PFLU_RS04440 outer membrane lipid asymmetry maintenance protein MlaD low > 109
Pseudomonas fluorescens SBW25 0.45 PFLU_RS28405 radical SAM family heme chaperone HemW 0.32 PFLU_RS04440 outer membrane lipid asymmetry maintenance protein MlaD low > 109
Pseudomonas fluorescens FW300-N2E2 0.44 Pf6N2E2_4593 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.29 Pf6N2E2_3258 Uncharacterized ABC transporter, periplasmic component YrbD low > 103
Pseudomonas fluorescens FW300-N2E3 0.44 AO353_08200 coproporphyrinogen III oxidase 0.32 AO353_05140 outer membrane lipid asymmetry maintenance protein MlaD low > 101
Pseudomonas fluorescens FW300-N1B4 0.44 Pf1N1B4_2334 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.30 Pf1N1B4_1072 Uncharacterized ABC transporter, periplasmic component YrbD
Pseudomonas sp. S08-1 0.44 OH686_11020 Oxygen-independent coproporphyrinogen-III oxidase-like protein YggW 0.32 OH686_08500 outer membrane lipid asymmetry maintenance protein MlaD low > 80
Pseudomonas fluorescens GW456-L13 0.44 PfGW456L13_1003 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.30 PfGW456L13_5006 Uncharacterized ABC transporter, periplasmic component YrbD low > 87
Pseudomonas fluorescens FW300-N2C3 0.43 AO356_13390 coproporphyrinogen III oxidase 0.29 AO356_06995 outer membrane lipid asymmetry maintenance protein MlaD low > 104
Enterobacter sp. TBS_079 0.43 MPMX20_03813 Heme chaperone HemW 0.38 MPMX20_04099 Intermembrane phospholipid transport system binding protein MlaD low > 85
Pseudomonas sp. RS175 0.43 PFR28_04249 Heme chaperone HemW 0.30 PFR28_00181 Intermembrane phospholipid transport system binding protein MlaD low > 88
Pseudomonas putida KT2440 0.43 PP_5101 coproporphyrinogen/heterocyclic compound oxidase (aerobic) 0.31 PP_0960 phospholipid ABC transporter binding protein low > 96
Pseudomonas syringae pv. syringae B728a ΔmexB 0.43 Psyr_0471 coproporphyrinogen III oxidase, anaerobic 0.30 Psyr_4139 Mce4/Rv3499c/MTV023.06c protein low > 86
Pseudomonas syringae pv. syringae B728a 0.43 Psyr_0471 coproporphyrinogen III oxidase, anaerobic 0.30 Psyr_4139 Mce4/Rv3499c/MTV023.06c protein low > 86
Serratia liquefaciens MT49 0.43 IAI46_21435 radical SAM family heme chaperone HemW 0.39 IAI46_22420 outer membrane lipid asymmetry maintenance protein MlaD low > 86
Escherichia coli BL21 0.42 ECD_02785 HemN family putative oxidoreductase 0.40 ECD_03058 OM lipid asymmetry maintenance protein; membrane-anchored ABC family periplasmic binding protein low > 61
Shewanella oneidensis MR-1 0.42 SO3359 oxygen-independent coproporphyrinogen III oxidase, putative (NCBI ptt file) 0.34 SO3952 mce-related protein (NCBI ptt file) low > 76
Pectobacterium carotovorum WPP14 0.42 HER17_RS03785 radical SAM family heme chaperone HemW 0.40 HER17_RS20015 outer membrane lipid asymmetry maintenance protein MlaD low > 75
Escherichia coli ECOR38 0.42 HEPCGN_18540 hemW radical SAM family heme chaperone HemW 0.40 HEPCGN_16860 mlaD outer membrane lipid asymmetry maintenance protein MlaD low > 87
Enterobacter asburiae PDN3 0.42 EX28DRAFT_2993 putative oxygen-independent coproporphyrinogen III oxidase 0.38 EX28DRAFT_3247 mce related protein low > 76
Escherichia fergusonii Becca 0.42 EFB2_00947 Heme chaperone HemW 0.40 EFB2_00630 Intermembrane phospholipid transport system binding protein MlaD low > 86
Klebsiella michiganensis M5al 0.42 BWI76_RS24120 YggW family oxidoreductase 0.37 BWI76_RS25220 outer membrane lipid asymmetry maintenance protein MlaD low > 92
Dickeya dadantii 3937 0.42 DDA3937_RS17325 radical SAM family heme chaperone HemW 0.40 DDA3937_RS01575 outer membrane lipid asymmetry maintenance protein MlaD low > 74
Pseudomonas stutzeri RCH2 0.42 Psest_0276 putative oxygen-independent coproporphyrinogen III oxidase 0.31 Psest_3305 ABC-type transport system involved in resistance to organic solvents, periplasmic component 0.27 6
Escherichia coli ECRC99 0.42 KEDOAH_08905 hemW radical SAM family heme chaperone HemW 0.40 KEDOAH_10165 mlaD outer membrane lipid asymmetry maintenance protein MlaD
Escherichia coli ECRC102 0.42 NIAGMN_17000 hemW radical SAM family heme chaperone HemW 0.40 NIAGMN_15745 mlaD outer membrane lipid asymmetry maintenance protein MlaD
Shewanella sp. ANA-3 0.42 Shewana3_1188 putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) 0.34 Shewana3_0680 hypothetical protein (RefSeq) low > 73
Escherichia coli Nissle 1917 0.42 ECOLIN_RS16435 radical SAM family heme chaperone HemW 0.40 ECOLIN_RS18380 outer membrane lipid asymmetry maintenance protein MlaD low > 55
Escherichia coli ECRC100 0.42 OKFHMN_19235 hemW radical SAM family heme chaperone HemW 0.40 OKFHMN_17985 mlaD outer membrane lipid asymmetry maintenance protein MlaD low > 80
Escherichia coli ECRC101 0.42 MCAODC_09755 hemW radical SAM family heme chaperone HemW 0.40 MCAODC_08505 mlaD outer membrane lipid asymmetry maintenance protein MlaD low > 87
Escherichia coli ECRC98 0.42 JDDGAC_22865 hemW radical SAM family heme chaperone HemW 0.40 JDDGAC_21610 mlaD outer membrane lipid asymmetry maintenance protein MlaD low > 86
Erwinia tracheiphila SCR3 0.42 LU632_RS05445 hemW radical SAM family heme chaperone HemW 0.31 LU632_RS21235 mlaD outer membrane lipid asymmetry maintenance protein MlaD low > 74
Escherichia coli BW25113 0.42 b2955 yggW coproporphyrinogen III oxidase (NCBI) 0.40 b3193 yrbD predicted ABC-type organic solvent transporter (NCBI) low > 76
Dickeya dianthicola 67-19 0.42 HGI48_RS17370 radical SAM family heme chaperone HemW 0.41 HGI48_RS01490 outer membrane lipid asymmetry maintenance protein MlaD low > 71
Escherichia coli HS(pFamp)R (ATCC 700891) 0.42 OHPLBJKB_00761 Oxygen-independent coproporphyrinogen-III oxidase-like protein YqeR 0.40 OHPLBJKB_00507 putative phospholipid ABC transporter-binding protein MlaD low > 73
Rahnella sp. WP5 0.41 EX31_RS02710 radical SAM family heme chaperone HemW 0.37 EX31_RS12445 outer membrane lipid asymmetry maintenance protein MlaD low > 89
Dickeya dianthicola ME23 0.41 DZA65_RS18460 radical SAM family heme chaperone HemW 0.41 DZA65_RS01555 outer membrane lipid asymmetry maintenance protein MlaD low > 75
Escherichia coli ECRC62 0.41 BNILDI_09685 hemW radical SAM family heme chaperone HemW 0.40 BNILDI_01750 mlaD outer membrane lipid asymmetry maintenance protein MlaD low > 75
Escherichia coli ECOR27 0.41 NOLOHH_11105 hemW radical SAM family heme chaperone HemW 0.40 NOLOHH_09785 mlaD outer membrane lipid asymmetry maintenance protein MlaD low > 75
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.41 GFF3058 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.38 GFF2937 Uncharacterized ABC transporter, periplasmic component YrbD low > 78
Pantoea sp. MT58 0.41 IAI47_03580 radical SAM family heme chaperone HemW 0.34 IAI47_17135 outer membrane lipid asymmetry maintenance protein MlaD low > 76
Vibrio cholerae E7946 ATCC 55056 0.41 CSW01_02425 YggW family oxidoreductase 0.35 CSW01_12765 outer membrane lipid asymmetry maintenance protein MlaD low > 62
Shewanella loihica PV-4 0.40 Shew_1131 putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) 0.34 Shew_3302 hypothetical protein (RefSeq) low > 60
Shewanella amazonensis SB2B 0.39 Sama_2483 oxygen-independent coproporphyrinogen III oxidase, putative (RefSeq) 0.36 Sama_3079 mce-related protein (RefSeq) low > 62
Alteromonas macleodii MIT1002 0.38 MIT1002_00939 Oxygen-independent coproporphyrinogen-III oxidase 1 0.34 MIT1002_00836 putative phospholipid ABC transporter-binding protein MlaD low > 70
Marinobacter adhaerens HP15 0.37 HP15_280 putative oxygen-independent coproporphyrinogen III oxidase 0.30 HP15_2434 mammalian cell entry related domain protein low > 73
Acinetobacter radioresistens SK82 0.37 MPMX26_00308 Heme chaperone HemW 0.25 MPMX26_02739 Intermembrane phospholipid transport system binding protein MlaD low > 36
Dinoroseobacter shibae DFL-12 0.31 Dshi_3460 putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) 0.18 Dshi_1391 Mammalian cell entry related domain protein (RefSeq) low > 64
Azospirillum sp. SherDot2 0.30 MPMX19_02574 Heme chaperone HemW 0.25 MPMX19_01649 Intermembrane phospholipid transport system binding protein MlaD
Phaeobacter inhibens DSM 17395 0.29 PGA1_c35050 oxygen-independent coproporphyrinogen III oxidase HemN 0.18 PGA1_c12570 ABC-type transport system involved in resistance to organic solvents, periplasmic component low > 62
Azospirillum brasilense Sp245 0.29 AZOBR_RS02195 coproporphyrinogen III oxidase 0.26 AZOBR_RS11990 ATPase AAA low > 97
Rhodospirillum rubrum S1H 0.26 Rru_A3639 Putative oxygen-independent coproporphyrinogen III oxidase (NCBI) 0.22 Rru_A2438 Mammalian cell entry related (NCBI)
Desulfovibrio vulgaris Miyazaki F 0.22 DvMF_2374 oxygen-independent coproporphyrinogen III oxidase (RefSeq) 0.29 DvMF_0854 Mammalian cell entry related domain protein (RefSeq) low > 51

Not shown: 20 genomes with orthologs for ABZR87_RS15265 only; 1 genomes with orthologs for ABZR87_RS02545 only