Conservation of cofitness between A4249_RS03600 and A4249_RS05505 in Brevundimonas sp. GW460-12-10-14-LB2

76 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Brevundimonas sp. GW460-12-10-14-LB2 1.0 A4249_RS03600 LacI family DNA-binding transcriptional regulator 1.0 A4249_RS05505 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.57 8
Lysobacter sp. OAE881 0.42 ABIE51_RS08800 LacI family DNA-binding transcriptional regulator 0.31 ABIE51_RS17265 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Rhodanobacter sp. FW510-T8 0.42 OKGIIK_15435 LacI family transcriptional regulator 0.31 OKGIIK_12100 spoT guanosine-3',5'-bis(diphosphate) 3'-diphosphatase
Dyella japonica UNC79MFTsu3.2 0.42 ABZR86_RS14885 LacI family DNA-binding transcriptional regulator 0.31 ABZR86_RS11850 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Rhodanobacter denitrificans FW104-10B01 0.41 LRK54_RS08670 LacI family transcriptional regulator 0.30 LRK54_RS11795 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Rhodanobacter denitrificans MT42 0.41 LRK55_RS08435 LacI family DNA-binding transcriptional regulator 0.31 LRK55_RS11520 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Xanthomonas campestris pv. campestris strain 8004 0.39 Xcc-8004.2362.1 Transcriptional regulator, LacI family 0.30 Xcc-8004.1215.1 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Sphingomonas koreensis DSMZ 15582 0.38 Ga0059261_2309 transcriptional regulator, LacI family 0.46 Ga0059261_1293 (p)ppGpp synthetase, RelA/SpoT family 0.71 1
Pectobacterium carotovorum WPP14 0.26 HER17_RS03725 LacI family DNA-binding transcriptional regulator 0.34 HER17_RS21385 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 75
Escherichia coli ECOR38 0.25 HEPCGN_22795 galS HTH-type transcriptional regulator GalS 0.33 HEPCGN_14375 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 87
Shewanella amazonensis SB2B 0.25 Sama_1400 periplasmic binding protein/LacI transcriptional regulator (RefSeq) 0.35 Sama_0264 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) low > 62
Escherichia coli BW25113 0.25 b2151 galS DNA-binding transcriptional repressor (NCBI) 0.34 b3650 spoT bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.25 OHPLBJKB_01560 HTH-type transcriptional regulator GalS 0.34 OHPLBJKB_00051 Bifunctional (p)ppGpp synthase/hydrolase SpoT low > 73
Escherichia coli ECOR27 0.25 NOLOHH_15100 galS HTH-type transcriptional regulator GalS 0.33 NOLOHH_07435 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 75
Escherichia coli BL21 0.25 ECD_02080 galactose- and fucose-inducible galactose regulon transcriptional isorepressor; mgl operon transcriptional repressor; autorepressor 0.33 ECD_03507 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 61
Dickeya dadantii 3937 0.25 DDA3937_RS00055 ribose operon transcriptional repressor RbsR 0.33 DDA3937_RS00180 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Escherichia coli Nissle 1917 0.25 ECOLIN_RS12585 HTH-type transcriptional regulator GalS 0.33 ECOLIN_RS20790 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 55
Escherichia fergusonii Becca 0.25 EFB2_01705 HTH-type transcriptional regulator GalS 0.33 EFB2_00138 Bifunctional (p)ppGpp synthase/hydrolase SpoT low > 86
Escherichia coli ECRC101 0.25 MCAODC_14575 galS HTH-type transcriptional regulator GalS 0.33 MCAODC_06065 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 87
Escherichia coli ECRC100 0.25 OKFHMN_23525 galS HTH-type transcriptional regulator GalS 0.33 OKFHMN_15555 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 80
Escherichia coli ECRC98 0.25 JDDGAC_27485 galS HTH-type transcriptional regulator GalS 0.33 JDDGAC_19180 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 86
Escherichia coli ECRC99 0.25 KEDOAH_04660 galS HTH-type transcriptional regulator GalS 0.33 KEDOAH_12590 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Escherichia coli ECRC102 0.25 NIAGMN_21290 galS HTH-type transcriptional regulator GalS 0.33 NIAGMN_13315 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Dickeya dianthicola 67-19 0.25 HGI48_RS21310 ribose operon transcriptional repressor RbsR 0.33 HGI48_RS21180 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Rahnella sp. WP5 0.25 EX31_RS14230 DNA-binding transcriptional regulator CytR 0.35 EX31_RS15810 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 89
Escherichia coli ECRC62 0.25 BNILDI_14020 galS HTH-type transcriptional regulator GalS 0.33 BNILDI_04080 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 75
Dickeya dianthicola ME23 0.25 DZA65_RS18545 LacI family transcriptional regulator 0.33 DZA65_RS22150 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Echinicola vietnamensis KMM 6221, DSM 17526 0.24 Echvi_3495 Transcriptional regulators 0.25 Echvi_4631 (p)ppGpp synthetase, RelA/SpoT family low > 79
Pseudomonas fluorescens FW300-N2E3 0.24 AO353_20830 LacI family transcriptional regulator 0.32 AO353_09280 (p)ppGpp synthetase
Pseudomonas fluorescens FW300-N2E2 0.24 Pf6N2E2_164 Ribose operon repressor 0.32 Pf6N2E2_4361 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Caulobacter crescentus NA1000 Δfur 0.24 CCNA_01699 LacI-family transcriptional regulator 0.71 CCNA_01622 Rsh ppGpp hydrolase-synthetase low > 67
Enterobacter asburiae PDN3 0.24 EX28DRAFT_0406 Transcriptional regulators 0.34 EX28DRAFT_3899 (p)ppGpp synthetase, RelA/SpoT family low > 76
Klebsiella michiganensis M5al 0.24 BWI76_RS23355 LacI family transcriptional regulator 0.34 BWI76_RS27430 (p)ppGpp synthetase low > 92
Caulobacter crescentus NA1000 0.24 CCNA_01699 LacI-family transcriptional regulator 0.71 CCNA_01622 Rsh ppGpp hydrolase-synthetase low > 66
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.24 GFF3787 Mgl repressor and galactose ultrainduction factor GalS, HTH-type transcriptional regulator 0.34 GFF357 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 low > 78
Pseudomonas fluorescens FW300-N2C3 0.24 AO356_00955 LacI family transcriptional regulator 0.32 AO356_12480 (p)ppGpp synthetase
Vibrio cholerae E7946 ATCC 55056 0.24 CSW01_13525 DNA-binding transcriptional regulator CytR 0.34 CSW01_13675 bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase low > 62
Pseudomonas syringae pv. syringae B728a ΔmexB 0.24 Psyr_2154 transcriptional regulator, LacI family 0.32 Psyr_0209 RelA/SpoT protein
Hydrogenophaga sp. GW460-11-11-14-LB1 0.24 GFF4454 Transcriptional regulator, LacI family 0.31 GFF1034 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Pseudomonas syringae pv. syringae B728a 0.24 Psyr_2154 transcriptional regulator, LacI family 0.32 Psyr_0209 RelA/SpoT protein
Pseudomonas sp. RS175 0.23 PFR28_02734 Ribose operon repressor 0.32 PFR28_04424 Bifunctional (p)ppGpp synthase/hydrolase SpoT
Erwinia tracheiphila SCR3 0.23 LU632_RS08515 galS HTH-type transcriptional regulator GalS 0.33 LU632_RS22200 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 74
Ralstonia solanacearum UW163 0.23 UW163_RS11705 LacI family transcriptional regulator 0.34 UW163_RS10410 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Ralstonia solanacearum IBSBF1503 0.23 RALBFv3_RS14240 LacI family transcriptional regulator 0.34 RALBFv3_RS03315 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 76
Pontibacter actiniarum KMM 6156, DSM 19842 0.23 CA264_13975 LacI family transcriptional regulator 0.26 CA264_01425 RelA/SpoT family protein low > 74
Enterobacter sp. TBS_079 0.23 MPMX20_03121 HTH-type transcriptional regulator GalS 0.34 MPMX20_00086 Bifunctional (p)ppGpp synthase/hydrolase SpoT low > 85
Pseudomonas fluorescens FW300-N1B4 0.23 Pf1N1B4_6032 Ribose operon repressor 0.32 Pf1N1B4_2113 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Ralstonia solanacearum GMI1000 0.23 RS_RS05020 LacI family transcriptional regulator 0.34 RS_RS10800 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Ralstonia solanacearum PSI07 0.23 RPSI07_RS19225 LacI family transcriptional regulator 0.34 RPSI07_RS13870 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 81
Alteromonas macleodii MIT1002 0.23 MIT1002_04103 Galactose operon repressor 0.35 MIT1002_00108 Bifunctional (p)ppGpp synthase/hydrolase SpoT low > 70
Pantoea sp. MT58 0.23 IAI47_10795 HTH-type transcriptional repressor PurR 0.34 IAI47_00510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase low > 76
Ralstonia sp. UNC404CL21Col 0.23 ABZR87_RS09955 LacI family DNA-binding transcriptional regulator 0.34 ABZR87_RS15225 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 80
Pseudomonas fluorescens SBW25-INTG 0.22 PFLU_RS20365 LacI family DNA-binding transcriptional regulator 0.32 PFLU_RS29510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Pseudomonas fluorescens SBW25 0.22 PFLU_RS20365 LacI family DNA-binding transcriptional regulator 0.32 PFLU_RS29510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase
Sinorhizobium meliloti 1021 0.22 SM_b20014 transcriptional regulator 0.42 SMc02659 GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein low > 103
Herbaspirillum seropedicae SmR1 0.22 HSERO_RS11495 LacI family transcription regulator 0.33 HSERO_RS10635 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Pseudomonas fluorescens GW456-L13 0.22 PfGW456L13_3909 Ribose operon repressor 0.32 PfGW456L13_780 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Paraburkholderia sabiae LMG 24235 0.22 QEN71_RS07355 LacI family DNA-binding transcriptional regulator 0.33 QEN71_RS03665 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 153
Agrobacterium fabrum C58 0.22 Atu5078 LacI family transcription regulator 0.43 Atu1030 GTP pyrophosphohydrolase/synthetase, RelA/SpoT family low > 89
Azospirillum sp. SherDot2 0.22 MPMX19_03117 Catabolite control protein A 0.49 MPMX19_00838 GTP pyrophosphokinase rsh low > 112
Variovorax sp. OAS795 0.22 ABID97_RS24770 LacI family DNA-binding transcriptional regulator 0.31 ABID97_RS23670 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Mucilaginibacter yixingensis YX-36 DSM 26809 0.22 ABZR88_RS10530 LacI family DNA-binding transcriptional regulator 0.29 ABZR88_RS15610 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 71
Variovorax sp. SCN45 0.21 GFF2137 Ribose operon repressor 0.31 GFF2375 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II
Pedobacter sp. GW460-11-11-14-LB5 0.21 CA265_RS06750 LacI family transcriptional regulator 0.29 CA265_RS14485 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 88
Pseudomonas putida KT2440 0.21 PP_2457 DNA-binding transcriptional repressor 0.32 PP_5302 bifunctional (p)ppGpp synthase/hydrolase
Paraburkholderia graminis OAS925 0.21 ABIE53_002322 LacI family transcriptional regulator 0.33 ABIE53_003230 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 113
Phaeobacter inhibens DSM 17395 0.21 PGA1_c07800 putative transcriptional regulator, lacI family 0.41 PGA1_c01010 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase SpoT low > 62
Paraburkholderia bryophila 376MFSha3.1 0.21 H281DRAFT_05228 transcriptional regulator, LacI family 0.33 H281DRAFT_04004 (p)ppGpp synthetase I, SpoT/RelA low > 103
Bifidobacterium breve UCC2003 0.20 BBR_RS13080 LacI family DNA-binding transcriptional regulator 0.29 BBR_RS16410 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Cupriavidus basilensis FW507-4G11 0.19 RR42_RS27820 GntR family transcriptional regulator 0.35 RR42_RS04920 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Rhizobium sp. OAE497 0.19 ABIE40_RS16795 LacI family DNA-binding transcriptional regulator 0.42 ABIE40_RS06050 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 107
Dinoroseobacter shibae DFL-12 0.18 Dshi_2238 transcriptional regulator, LacI family (RefSeq) 0.42 Dshi_0194 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) low > 64
Bacteroides stercoris CC31F 0.18 HMPREF1181_RS05535 LacI family DNA-binding transcriptional regulator 0.24 HMPREF1181_RS09205 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Bacteroides ovatus ATCC 8483 0.18 BACOVA_02049 sugar-binding domain protein 0.24 BACOVA_04817 RelA/SpoT family protein
Rhodospirillum rubrum S1H 0.18 Rru_A1973 Transcriptional Regulator, LacI family (NCBI) 0.51 Rru_A1856 (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA (NCBI)
Azospirillum brasilense Sp245 0.17 AZOBR_RS32320 LacI family transcriptional regulator 0.51 AZOBR_RS22045 GTP pyrophosphokinase 0.35 49
Pseudomonas stutzeri RCH2 0.16 Psest_2126 Transcriptional regulators 0.31 Psest_3817 (p)ppGpp synthetase, RelA/SpoT family

Not shown: 0 genomes with orthologs for A4249_RS03600 only; 25 genomes with orthologs for A4249_RS05505 only