Conservation of cofitness between BT0738 and BT3395 in Bacteroides thetaiotaomicron VPI-5482

75 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT0738 serine hydroxymethyltransferase (NCBI ptt file) 1.0 BT3395 N-succinylglutamate kinase (EC 2.7.2.-) (from data) 0.86 10
Bacteroides ovatus ATCC 8483 0.99 BACOVA_02446 glycine hydroxymethyltransferase 0.96 BACOVA_01910 acetylglutamate kinase 0.96 5
Phocaeicola vulgatus CL09T03C04 0.98 HMPREF1058_RS03800 serine hydroxymethyltransferase 0.86 HMPREF1058_RS12115 acetylglutamate kinase low > 67
Phocaeicola dorei CL03T12C01 0.97 ABI39_RS17420 serine hydroxymethyltransferase 0.85 ABI39_RS04685 acetylglutamate kinase low > 72
Bacteroides stercoris CC31F 0.96 HMPREF1181_RS15010 serine hydroxymethyltransferase 0.87 HMPREF1181_RS02540 acetylglutamate kinase 0.68 54
Parabacteroides merdae CL09T00C40 0.83 HMPREF1078_RS02145 serine hydroxymethyltransferase 0.77 HMPREF1078_RS15335 acetylglutamate kinase low > 61
Pontibacter actiniarum KMM 6156, DSM 19842 0.69 CA264_17045 serine hydroxymethyltransferase 0.54 CA264_06235 acetylglutamate kinase low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.67 ABZR88_RS00640 serine hydroxymethyltransferase 0.56 ABZR88_RS09860 acetylglutamate kinase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.65 Echvi_1188 Glycine/serine hydroxymethyltransferase 0.52 Echvi_3850 acetylglutamate kinase 0.89 19
Pedobacter sp. GW460-11-11-14-LB5 0.65 CA265_RS19165 serine hydroxymethyltransferase 0.55 CA265_RS18510 acetylglutamate kinase — —
Shewanella amazonensis SB2B 0.54 Sama_1014 glyA serine hydroxymethyltransferase (RefSeq) 0.16 Sama_0257 acetylglutamate kinase (RefSeq) 0.89 44
Marinobacter adhaerens HP15 0.54 HP15_489 glycine hydroxymethyltransferase 0.25 HP15_3317 acetylglutamate kinase — —
Shewanella loihica PV-4 0.54 Shew_1185 glyA serine hydroxymethyltransferase (RefSeq) 0.17 Shew_0203 acetylglutamate kinase (RefSeq) 0.92 22
Shewanella sp. ANA-3 0.54 Shewana3_1094 glyA serine hydroxymethyltransferase (RefSeq) 0.17 Shewana3_3904 acetylglutamate kinase (RefSeq) 0.88 56
Pseudomonas stutzeri RCH2 0.53 Psest_3404 Glycine/serine hydroxymethyltransferase 0.26 Psest_3807 acetylglutamate kinase — —
Pseudomonas sp. RS175 0.53 PFR28_03786 Serine hydroxymethyltransferase 0.25 PFR28_04416 Acetylglutamate kinase — —
Pseudomonas fluorescens FW300-N2C3 0.53 AO356_15725 serine hydroxymethyltransferase 0.25 AO356_12525 acetylglutamate kinase — —
Shewanella oneidensis MR-1 0.53 SO3471 glyA serine hydroxymethyltransferase (NCBI ptt file) 0.17 SO0276 argB acetylglutamate kinase (NCBI ptt file) 0.90 49
Pseudomonas fluorescens FW300-N1B4 0.53 Pf1N1B4_2778 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.25 Pf1N1B4_2121 Acetylglutamate kinase (EC 2.7.2.8) — —
Castellaniella sp019104865 MT123 0.53 ABCV34_RS06400 serine hydroxymethyltransferase 0.21 ABCV34_RS14295 acetylglutamate kinase — —
Pseudomonas fluorescens FW300-N2E2 0.53 Pf6N2E2_5082 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.25 Pf6N2E2_4373 Acetylglutamate kinase (EC 2.7.2.8) — —
Pseudomonas fluorescens FW300-N2E3 0.53 AO353_14020 serine hydroxymethyltransferase 0.25 AO353_09240 acetylglutamate kinase — —
Pseudomonas fluorescens SBW25-INTG 0.53 PFLU_RS26195 serine hydroxymethyltransferase 0.25 PFLU_RS29470 acetylglutamate kinase — —
Pseudomonas fluorescens SBW25 0.53 PFLU_RS26195 serine hydroxymethyltransferase 0.25 PFLU_RS29470 acetylglutamate kinase — —
Caulobacter crescentus NA1000 Δfur 0.53 CCNA_01419 serine hydroxymethyltransferase 0.22 CCNA_00285 acetylglutamate kinase — —
Caulobacter crescentus NA1000 0.53 CCNA_01419 serine hydroxymethyltransferase 0.22 CCNA_00285 acetylglutamate kinase — —
Dickeya dianthicola ME23 0.53 DZA65_RS16775 serine hydroxymethyltransferase 0.16 DZA65_RS00940 acetylglutamate kinase — —
Dickeya dadantii 3937 0.52 DDA3937_RS15600 serine hydroxymethyltransferase 0.17 DDA3937_RS20345 acetylglutamate kinase — —
Pseudomonas simiae WCS417 0.52 PS417_24280 serine hydroxymethyltransferase 0.25 PS417_27790 acetylglutamate kinase — —
Pseudomonas fluorescens GW456-L13 0.52 PfGW456L13_1451 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.25 PfGW456L13_793 Acetylglutamate kinase (EC 2.7.2.8) — —
Dickeya dianthicola 67-19 0.52 HGI48_RS15700 serine hydroxymethyltransferase 0.16 HGI48_RS00880 acetylglutamate kinase — —
Pectobacterium carotovorum WPP14 0.52 HER17_RS05950 serine hydroxymethyltransferase 0.17 HER17_RS20625 acetylglutamate kinase — —
Pantoea sp. MT58 0.52 IAI47_04960 serine hydroxymethyltransferase 0.17 IAI47_00910 acetylglutamate kinase — —
Erwinia tracheiphila SCR3 0.51 LU632_RS17915 serine hydroxymethyltransferase 0.16 LU632_RS19610 argB acetylglutamate kinase — —
Rahnella sp. WP5 0.51 EX31_RS20585 serine hydroxymethyltransferase 0.15 EX31_RS14185 acetylglutamate kinase — —
Agrobacterium fabrum C58 0.51 Atu1165 serine hydroxymethyltransferase 0.27 Atu0380 acetylglutamate kinase — —
Serratia liquefaciens MT49 0.50 IAI46_19395 serine hydroxymethyltransferase 0.16 IAI46_24510 acetylglutamate kinase — —
Herbaspirillum seropedicae SmR1 0.50 HSERO_RS06140 serine hydroxymethyltransferase 0.22 HSERO_RS21495 acetylglutamate kinase — —
Paraburkholderia sabiae LMG 24235 0.50 QEN71_RS26235 serine hydroxymethyltransferase 0.22 QEN71_RS00305 acetylglutamate kinase — —
Rhizobium sp. OAE497 0.50 ABIE40_RS06715 serine hydroxymethyltransferase 0.27 ABIE40_RS01970 acetylglutamate kinase — —
Burkholderia phytofirmans PsJN 0.50 BPHYT_RS03725 serine hydroxymethyltransferase 0.22 BPHYT_RS01610 acetylglutamate kinase — —
Paraburkholderia bryophila 376MFSha3.1 0.50 H281DRAFT_04726 serine hydroxymethyltransferase 0.22 H281DRAFT_02211 N-acetylglutamate kinase — —
Paraburkholderia graminis OAS925 0.50 ABIE53_000888 glycine hydroxymethyltransferase 0.22 ABIE53_000417 acetylglutamate kinase — —
Sinorhizobium meliloti 1021 0.50 SMc01770 serine hydroxymethyltransferase 0.27 SMc01726 acetylglutamate kinase 0.93 12
Escherichia coli HS(pFamp)R (ATCC 700891) 0.50 OHPLBJKB_01156 Serine hydroxymethyltransferase 0.15 OHPLBJKB_04091 Acetylglutamate kinase low > 73
Hydrogenophaga sp. GW460-11-11-14-LB1 0.50 GFF5152 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.23 GFF409 Acetylglutamate kinase (EC 2.7.2.8) — —
Escherichia coli BL21 0.50 ECD_02443 serine hydroxymethyltransferase 0.15 ECD_03844 acetylglutamate kinase low > 60
Rhodopseudomonas palustris CGA009 0.50 TX73_014115 serine hydroxymethyltransferase 0.27 TX73_003255 acetylglutamate kinase — —
Escherichia coli ECOR27 0.50 NOLOHH_13185 glyA serine hydroxymethyltransferase 0.15 NOLOHH_05725 acetylglutamate kinase low > 57
Escherichia coli ECOR38 0.50 HEPCGN_20655 glyA serine hydroxymethyltransferase 0.15 HEPCGN_12225 acetylglutamate kinase low > 85
Escherichia fergusonii Becca 0.50 EFB2_01345 Serine hydroxymethyltransferase 0.15 EFB2_04655 Acetylglutamate kinase — —
Escherichia coli Nissle 1917 0.50 ECOLIN_RS14440 serine hydroxymethyltransferase 0.15 ECOLIN_RS22850 acetylglutamate kinase — —
Escherichia coli ECRC62 0.50 BNILDI_11985 glyA serine hydroxymethyltransferase 0.15 BNILDI_05800 acetylglutamate kinase — —
Escherichia coli BW25113 0.50 b2551 glyA serine hydroxymethyltransferase (NCBI) 0.15 b3959 argB acetylglutamate kinase (RefSeq) — —
Escherichia coli ECRC102 0.50 NIAGMN_19280 glyA serine hydroxymethyltransferase 0.15 NIAGMN_11330 acetylglutamate kinase — —
Escherichia coli ECRC98 0.50 JDDGAC_25175 glyA serine hydroxymethyltransferase 0.15 JDDGAC_17205 acetylglutamate kinase — —
Escherichia coli ECRC99 0.50 KEDOAH_06710 glyA serine hydroxymethyltransferase 0.15 KEDOAH_14580 acetylglutamate kinase — —
Escherichia coli ECRC101 0.50 MCAODC_12040 glyA serine hydroxymethyltransferase 0.15 MCAODC_04080 acetylglutamate kinase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.50 GFF2447 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.13 GFF2345 Acetylglutamate kinase (EC 2.7.2.8) — —
Escherichia coli ECRC101 0.50 OKFHMN_21510 glyA serine hydroxymethyltransferase 0.15 OKFHMN_13580 acetylglutamate kinase — —
Enterobacter sp. TBS_079 0.49 MPMX20_03420 Serine hydroxymethyltransferase 0.14 MPMX20_04521 Acetylglutamate kinase — —
Klebsiella michiganensis M5al 0.49 BWI76_RS21225 serine hydroxymethyltransferase 0.15 BWI76_RS00850 acetylglutamate kinase — —
Vibrio cholerae E7946 ATCC 55056 0.49 CSW01_04820 serine hydroxymethyltransferase 0.16 CSW01_13375 acetylglutamate kinase low > 62
Dechlorosoma suillum PS 0.49 Dsui_1265 glycine/serine hydroxymethyltransferase 0.24 Dsui_1309 acetylglutamate kinase — —
Enterobacter asburiae PDN3 0.49 EX28DRAFT_0099 Glycine/serine hydroxymethyltransferase 0.14 EX28DRAFT_4421 N-acetylglutamate kinase (EC 2.7.2.8) — —
Dinoroseobacter shibae DFL-12 0.49 Dshi_2113 Glycine hydroxymethyltransferase (RefSeq) 0.23 Dshi_0324 acetylglutamate kinase (RefSeq) — —
Variovorax sp. OAS795 0.49 ABID97_RS17890 serine hydroxymethyltransferase 0.22 ABID97_RS05760 acetylglutamate kinase — —
Alteromonas macleodii MIT1002 0.49 MIT1002_02702 Serine hydroxymethyltransferase 0.18 MIT1002_00470 Acetylglutamate kinase 0.92 25
Phaeobacter inhibens DSM 17395 0.49 PGA1_c11870 serine hydroxymethyltransferase GlyA 0.26 PGA1_c02050 acetylglutamate kinase ArgB 0.75 44
Bosea sp. OAE506 0.49 ABIE41_RS19780 serine hydroxymethyltransferase 0.29 ABIE41_RS03980 acetylglutamate kinase — —
Variovorax sp. SCN45 0.48 GFF560 Serine hydroxymethyltransferase (EC 2.1.2.1) 0.22 GFF4624 N-acetylglutamate kinase (EC 2.7.2.8) — —
Brevundimonas sp. GW460-12-10-14-LB2 0.48 A4249_RS06040 serine hydroxymethyltransferase 0.23 A4249_RS12965 acetylglutamate kinase — —
Mycobacterium tuberculosis H37Rv 0.48 Rv0070c Serine hydroxymethyltransferase GlyA2 (serine methylase 2) (SHMT 2) 0.20 Rv1654 Probable acetylglutamate kinase ArgB — —
Azospirillum sp. SherDot2 0.46 MPMX19_00727 Serine hydroxymethyltransferase 2 0.21 MPMX19_00333 Acetylglutamate kinase — —
Azospirillum brasilense Sp245 0.45 AZOBR_RS10015 serine hydroxymethyltransferase 0.26 AZOBR_RS03285 acetylglutamate kinase — —
Sphingomonas koreensis DSMZ 15582 0.44 Ga0059261_1986 Glycine/serine hydroxymethyltransferase 0.23 Ga0059261_2530 N-acetylglutamate kinase (EC 2.7.2.8) 0.96 12

Not shown: 24 genomes with orthologs for BT0738 only; 2 genomes with orthologs for BT3395 only