Conservation of cofitness between b2499 and b3642 in Escherichia coli BW25113

70 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2499 purM phosphoribosylaminoimidazole synthetase (NCBI) 1.0 b3642 pyrE orotate phosphoribosyltransferase (NCBI) 0.89 11
Escherichia coli Nissle 1917 1.00 ECOLIN_RS14190 phosphoribosylformylglycinamidine cyclo-ligase 1.00 ECOLIN_RS20750 orotate phosphoribosyltransferase low > 52
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01227 Phosphoribosylformylglycinamidine cyclo-ligase 1.00 OHPLBJKB_00060 Orotate phosphoribosyltransferase 0.34 43
Escherichia coli BL21 1.00 ECD_02391 phosphoribosylaminoimidazole synthetase 1.00 ECD_03499 orotate phosphoribosyltransferase 0.74 12
Escherichia coli ECOR38 0.99 HEPCGN_20975 purM Phosphoribosylformylglycinamidine cyclo-ligase 1.00 HEPCGN_14420 pyrE Orotate phosphoribosyltransferase low > 85
Escherichia coli ECOR27 0.99 NOLOHH_13460 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.99 NOLOHH_07480 pyrE Orotate phosphoribosyltransferase low > 57
Escherichia fergusonii Becca 0.99 EFB2_01399 Phosphoribosylformylglycinamidine cyclo-ligase 1.00 EFB2_00171 Orotate phosphoribosyltransferase low > 86
Escherichia coli ECRC62 0.99 BNILDI_12270 purM Phosphoribosylformylglycinamidine cyclo-ligase 1.00 BNILDI_04035 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECRC101 0.99 MCAODC_12340 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.99 MCAODC_06110 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECRC99 0.99 KEDOAH_06410 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.99 KEDOAH_12550 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECRC102 0.99 NIAGMN_19580 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.99 NIAGMN_13360 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECRC98 0.99 JDDGAC_25755 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.99 JDDGAC_19225 pyrE Orotate phosphoribosyltransferase — —
Escherichia coli ECRC101 0.99 OKFHMN_21810 purM Phosphoribosylformylglycinamidine cyclo-ligase 0.99 OKFHMN_15600 pyrE Orotate phosphoribosyltransferase — —
Enterobacter asburiae PDN3 0.94 EX28DRAFT_0168 phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.96 EX28DRAFT_3892 orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Enterobacter sp. TBS_079 0.94 MPMX20_03354 Phosphoribosylformylglycinamidine cyclo-ligase 0.94 MPMX20_00093 Orotate phosphoribosyltransferase 0.80 54
Klebsiella michiganensis M5al 0.93 BWI76_RS20965 phosphoribosylformylglycinamidine cyclo-ligase 0.96 BWI76_RS27385 orotate phosphoribosyltransferase 0.69 63
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF2169 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.97 GFF367 Orotate phosphoribosyltransferase (EC 2.4.2.10) low > 78
Rahnella sp. WP5 0.90 EX31_RS22695 phosphoribosylformylglycinamidine cyclo-ligase 0.90 EX31_RS14500 orotate phosphoribosyltransferase 0.90 44
Pantoea sp. MT58 0.89 IAI47_05180 phosphoribosylformylglycinamidine cyclo-ligase 0.87 IAI47_00600 orotate phosphoribosyltransferase 0.97 9
Pectobacterium carotovorum WPP14 0.88 HER17_RS15465 phosphoribosylformylglycinamidine cyclo-ligase 0.90 HER17_RS20850 orotate phosphoribosyltransferase 0.92 37
Serratia liquefaciens MT49 0.88 IAI46_18885 phosphoribosylformylglycinamidine cyclo-ligase 0.91 IAI46_24845 orotate phosphoribosyltransferase 0.52 25
Erwinia tracheiphila SCR3 0.87 LU632_RS08275 purM phosphoribosylformylglycinamidine cyclo-ligase 0.88 LU632_RS22015 pyrE orotate phosphoribosyltransferase 0.90 9
Dickeya dadantii 3937 0.87 DDA3937_RS06025 phosphoribosylformylglycinamidine cyclo-ligase 0.90 DDA3937_RS20535 orotate phosphoribosyltransferase 0.93 4
Dickeya dianthicola ME23 0.86 DZA65_RS06420 phosphoribosylformylglycinamidine cyclo-ligase 0.88 DZA65_RS00735 orotate phosphoribosyltransferase 0.63 51
Dickeya dianthicola 67-19 0.86 HGI48_RS06070 phosphoribosylformylglycinamidine cyclo-ligase 0.88 HGI48_RS00680 orotate phosphoribosyltransferase 0.77 12
Shewanella amazonensis SB2B 0.77 Sama_2097 phosphoribosylaminoimidazole synthetase (RefSeq) 0.84 Sama_0321 pyrE orotate phosphoribosyltransferase (RefSeq) low > 62
Vibrio cholerae E7946 ATCC 55056 0.77 CSW01_11350 phosphoribosylformylglycinamidine cyclo-ligase 0.85 CSW01_01120 orotate phosphoribosyltransferase 0.68 3
Shewanella sp. ANA-3 0.76 Shewana3_2545 phosphoribosylaminoimidazole synthetase (RefSeq) 0.82 Shewana3_3776 pyrE orotate phosphoribosyltransferase (RefSeq) 0.85 59
Shewanella oneidensis MR-1 0.75 SO2760 purM phosphoribosylformylglycinamidine cyclo-ligase (NCBI ptt file) 0.82 SO4255 pyrE orotate phosphoribosyltransferase (NCBI ptt file) 0.88 21
Shewanella loihica PV-4 0.75 Shew_1513 phosphoribosylaminoimidazole synthetase (RefSeq) 0.83 Shew_3487 pyrE orotate phosphoribosyltransferase (RefSeq) — —
Alteromonas macleodii MIT1002 0.73 MIT1002_02219 Phosphoribosylformylglycinamidine cyclo-ligase 0.75 MIT1002_04070 Orotate phosphoribosyltransferase — —
Kangiella aquimarina DSM 16071 0.70 B158DRAFT_2385 phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.70 B158DRAFT_0786 orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Pseudomonas stutzeri RCH2 0.70 Psest_1474 phosphoribosylaminoimidazole synthetase 0.71 Psest_3810 orotate phosphoribosyltransferase 0.61 22
Pseudomonas putida KT2440 0.69 PP_1665 Phosphoribosylformylglycinamidine cyclo-ligase 0.67 PP_5291 Orotate phosphoribosyltransferase — —
Pseudomonas fluorescens SBW25 0.69 PFLU_RS22065 phosphoribosylformylglycinamidine cyclo-ligase 0.68 PFLU_RS29475 orotate phosphoribosyltransferase — —
Pseudomonas fluorescens SBW25-INTG 0.69 PFLU_RS22065 phosphoribosylformylglycinamidine cyclo-ligase 0.68 PFLU_RS29475 orotate phosphoribosyltransferase — —
Pseudomonas simiae WCS417 0.69 PS417_20120 phosphoribosylaminoimidazole synthetase 0.68 PS417_27795 orotate phosphoribosyltransferase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.69 Psyr_3689 phosphoribosylformylglycinamidine cyclo-ligase 0.72 Psyr_0216 orotate phosphoribosyltransferase — —
Pseudomonas sp. S08-1 0.69 OH686_18995 Phosphoribosylformylglycinamidine cyclo-ligase 0.69 OH686_13590 Orotate phosphoribosyltransferase — —
Pseudomonas fluorescens FW300-N2C3 0.69 AO356_19090 phosphoribosylaminoimidazole synthetase 0.67 AO356_12520 orotate phosphoribosyltransferase 0.64 43
Pseudomonas fluorescens FW300-N2E2 0.69 Pf6N2E2_5729 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.68 Pf6N2E2_4370 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Pseudomonas syringae pv. syringae B728a 0.69 Psyr_3689 phosphoribosylformylglycinamidine cyclo-ligase 0.72 Psyr_0216 orotate phosphoribosyltransferase — —
Pseudomonas fluorescens FW300-N1B4 0.68 Pf1N1B4_3698 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.67 Pf1N1B4_2120 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Pseudomonas sp. RS175 0.68 PFR28_03217 Phosphoribosylformylglycinamidine cyclo-ligase 0.71 PFR28_04417 Orotate phosphoribosyltransferase — —
Pseudomonas fluorescens FW300-N2E3 0.68 AO353_02680 phosphoribosylaminoimidazole synthetase 0.67 AO353_09245 orotate phosphoribosyltransferase — —
Pseudomonas fluorescens GW456-L13 0.68 PfGW456L13_4252 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.67 PfGW456L13_788 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Marinobacter adhaerens HP15 0.67 HP15_1299 phosphoribosylaminoimidazole synthetase 0.64 HP15_298 orotate phosphoribosyltransferase — —
Acinetobacter radioresistens SK82 0.67 MPMX26_02206 Phosphoribosylformylglycinamidine cyclo-ligase 0.56 MPMX26_02937 Orotate phosphoribosyltransferase 0.87 18
Dechlorosoma suillum PS 0.62 Dsui_1519 phosphoribosylaminoimidazole synthetase 0.58 Dsui_0873 orotate phosphoribosyltransferase — —
Cupriavidus basilensis FW507-4G11 0.59 RR42_RS17220 phosphoribosylaminoimidazole synthetase 0.55 RR42_RS01225 orotate phosphoribosyltransferase — —
Castellaniella sp019104865 MT123 0.56 ABCV34_RS08795 phosphoribosylformylglycinamidine cyclo-ligase 0.58 ABCV34_RS10890 orotate phosphoribosyltransferase — —
Herbaspirillum seropedicae SmR1 0.56 HSERO_RS03165 phosphoribosylaminoimidazole synthetase 0.55 HSERO_RS23380 orotate phosphoribosyltransferase — —
Rhodanobacter denitrificans MT42 0.56 LRK55_RS12645 phosphoribosylformylglycinamidine cyclo-ligase 0.59 LRK55_RS08720 orotate phosphoribosyltransferase low > 63
Rhodanobacter denitrificans FW104-10B01 0.56 LRK54_RS12945 phosphoribosylformylglycinamidine cyclo-ligase 0.59 LRK54_RS09190 orotate phosphoribosyltransferase — —
Ralstonia solanacearum PSI07 0.55 RPSI07_RS12020 phosphoribosylformylglycinamidine cyclo-ligase 0.52 RPSI07_RS23295 orotate phosphoribosyltransferase — —
Variovorax sp. OAS795 0.55 ABID97_RS08700 phosphoribosylformylglycinamidine cyclo-ligase 0.48 ABID97_RS03910 orotate phosphoribosyltransferase — —
Variovorax sp. SCN45 0.55 GFF3941 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.49 GFF5065 Orotate phosphoribosyltransferase (EC 2.4.2.10) low > 127
Hydrogenophaga sp. GW460-11-11-14-LB1 0.55 GFF3433 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.49 GFF1882 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Acidovorax sp. GW101-3H11 0.55 Ac3H11_1318 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.51 Ac3H11_3341 Orotate phosphoribosyltransferase (EC 2.4.2.10) — —
Ralstonia solanacearum UW163 0.55 UW163_RS08345 phosphoribosylformylglycinamidine cyclo-ligase 0.53 UW163_RS03505 orotate phosphoribosyltransferase — —
Ralstonia sp. UNC404CL21Col 0.55 ABZR87_RS00915 phosphoribosylformylglycinamidine cyclo-ligase 0.52 ABZR87_RS05590 orotate phosphoribosyltransferase — —
Ralstonia solanacearum IBSBF1503 0.55 RALBFv3_RS05280 phosphoribosylformylglycinamidine cyclo-ligase 0.53 RALBFv3_RS10075 orotate phosphoribosyltransferase — —
Ralstonia solanacearum GMI1000 0.54 RS_RS13145 phosphoribosylformylglycinamidine cyclo-ligase 0.52 RS_RS00685 orotate phosphoribosyltransferase — —
Xanthomonas campestris pv. campestris strain 8004 0.54 Xcc-8004.1676.1 Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) 0.47 Xcc-8004.4884.1 Orotate phosphoribosyltransferase (EC 2.4.2.10) low > 74
Lysobacter sp. OAE881 0.54 ABIE51_RS15890 phosphoribosylformylglycinamidine cyclo-ligase 0.46 ABIE51_RS00065 orotate phosphoribosyltransferase low > 62
Dyella japonica UNC79MFTsu3.2 0.53 ABZR86_RS19865 phosphoribosylformylglycinamidine cyclo-ligase 0.61 ABZR86_RS15640 orotate phosphoribosyltransferase low > 74
Rhodanobacter sp. FW510-T8 0.52 OKGIIK_02315 purM phosphoribosylformylglycinamidine cyclo-ligase 0.59 OKGIIK_15685 pyrE orotate phosphoribosyltransferase — —
Desulfovibrio vulgaris Miyazaki F 0.49 DvMF_0202 phosphoribosylaminoimidazole synthetase (RefSeq) 0.13 DvMF_1469 orotate phosphoribosyltransferase (RefSeq) — —
Bifidobacterium breve UCC2003 0.47 BBR_RS13375 phosphoribosylformylglycinamidine cyclo-ligase 0.41 BBR_RS15455 orotate phosphoribosyltransferase low > 34
Methanococcus maripaludis S2 0.29 MMP_RS06450 phosphoribosylformylglycinamidine cyclo-ligase 0.13 MMP_RS07670 orotate phosphoribosyltransferase — —
Methanococcus maripaludis JJ 0.29 MMJJ_RS07900 phosphoribosylformylglycinamidine cyclo-ligase 0.13 MMJJ_RS06690 orotate phosphoribosyltransferase — —

Not shown: 32 genomes with orthologs for b2499 only; 0 genomes with orthologs for b3642 only