Conservation of cofitness between b0945 and b1062 in Escherichia coli BW25113

74 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 1.0 b1062 pyrC dihydroorotase (NCBI) 0.97 1
Escherichia coli ECOR27 1.00 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 NOLOHH_21260 pyrC dihydroorotase low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) 1.00 OHPLBJKB_02603 Dihydroorotase 0.71 4
Escherichia coli BL21 1.00 ECD_00949 dihydro-orotate oxidase, FMN-linked 1.00 ECD_01058 dihydro-orotase low > 60
Escherichia coli ECRC98 1.00 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase 0.99 JDDGAC_07390 pyrC dihydroorotase — —
Escherichia coli ECRC101 1.00 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase 0.99 OKFHMN_03730 pyrC dihydroorotase — —
Escherichia coli ECRC99 1.00 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase 0.99 KEDOAH_24025 pyrC dihydroorotase — —
Escherichia coli ECRC62 1.00 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 BNILDI_19420 pyrC dihydroorotase — —
Escherichia coli ECRC101 1.00 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase 0.99 MCAODC_23090 pyrC dihydroorotase — —
Escherichia coli ECRC102 1.00 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase 0.99 NIAGMN_24100 pyrC dihydroorotase — —
Escherichia coli ECOR38 1.00 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase 1.00 HEPCGN_23760 pyrC dihydroorotase low > 85
Escherichia coli Nissle 1917 0.99 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase 0.99 ECOLIN_RS06160 dihydroorotase — —
Escherichia fergusonii Becca 0.99 EFB2_03126 Dihydroorotate dehydrogenase (quinone) 1.00 EFB2_02912 Dihydroorotase low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.91 GFF3342 Dihydroorotase (EC 3.5.2.3) 0.79 1
Enterobacter sp. TBS_079 0.94 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) 0.92 MPMX20_01741 Dihydroorotase 0.97 3
Enterobacter asburiae PDN3 0.94 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) 0.92 EX28DRAFT_1869 dihydroorotase (EC 3.5.2.3) — —
Klebsiella michiganensis M5al 0.93 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.90 BWI76_RS10990 dihydroorotase 0.88 3
Serratia liquefaciens MT49 0.87 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase 0.77 IAI46_09740 dihydroorotase 0.80 24
Pectobacterium carotovorum WPP14 0.86 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase 0.76 HER17_RS08600 dihydroorotase 0.98 2
Dickeya dianthicola ME23 0.86 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase 0.72 DZA65_RS13710 dihydroorotase 0.96 1
Rahnella sp. WP5 0.86 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.77 EX31_RS24385 dihydroorotase 0.94 11
Dickeya dadantii 3937 0.86 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase 0.72 DDA3937_RS13170 dihydroorotase 0.94 1
Dickeya dianthicola 67-19 0.85 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase 0.71 HGI48_RS13235 dihydroorotase 0.88 1
Erwinia tracheiphila SCR3 0.84 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase 0.75 LU632_RS10340 pyrC dihydroorotase 0.97 2
Pantoea sp. MT58 0.81 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.73 IAI47_12215 dihydroorotase 0.98 1
Vibrio cholerae E7946 ATCC 55056 0.72 CSW01_07490 dihydroorotate dehydrogenase (quinone) 0.54 CSW01_18760 dihydroorotase 0.76 2
Shewanella sp. ANA-3 0.63 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) 0.54 Shewana3_3263 dihydroorotase (RefSeq) 0.97 1
Shewanella loihica PV-4 0.63 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) 0.51 Shew_0728 dihydroorotase (RefSeq) 0.97 1
Shewanella amazonensis SB2B 0.62 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) 0.52 Sama_2870 dihydroorotase (RefSeq) 0.92 1
Shewanella oneidensis MR-1 0.62 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) 0.52 SO3695 pyrC dihydroorotase, homodimeric type (NCBI ptt file) 0.98 1
Alteromonas macleodii MIT1002 0.58 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) 0.53 MIT1002_03750 Dihydroorotase — —
Pseudomonas fluorescens SBW25 0.57 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.55 PFLU_RS05715 dihydroorotase — —
Pseudomonas fluorescens SBW25-INTG 0.57 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.55 PFLU_RS05715 dihydroorotase — —
Pseudomonas fluorescens FW300-N2E3 0.57 AO353_00780 dihydroorotate dehydrogenase (quinone) 0.55 AO353_04115 dihydroorotase — —
Pseudomonas fluorescens FW300-N1B4 0.57 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.56 Pf1N1B4_744 Dihydroorotase (EC 3.5.2.3) — —
Paraburkholderia sabiae LMG 24235 0.57 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase 0.53 QEN71_RS26855 dihydroorotase — —
Burkholderia phytofirmans PsJN 0.57 BPHYT_RS08565 dihydroorotate dehydrogenase 0.52 BPHYT_RS16675 dihydroorotase 0.82 1
Pseudomonas simiae WCS417 0.57 PS417_20935 dihydroorotate dehydrogenase 0.55 PS417_05630 dihydroorotase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.57 Psyr_2106 dihydroorotate oxidase A 0.54 Psyr_3894 dihydroorotase — —
Pseudomonas syringae pv. syringae B728a 0.57 Psyr_2106 dihydroorotate oxidase A 0.54 Psyr_3894 dihydroorotase — —
Paraburkholderia graminis OAS925 0.56 ABIE53_001954 dihydroorotate dehydrogenase 0.52 ABIE53_003505 dihydroorotase — —
Pseudomonas sp. RS175 0.56 PFR28_01054 Dihydroorotate dehydrogenase (quinone) 0.55 PFR28_03355 Dihydroorotase — —
Pseudomonas fluorescens FW300-N2E2 0.56 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.55 Pf6N2E2_5588 Dihydroorotase (EC 3.5.2.3) — —
Pseudomonas fluorescens GW456-L13 0.56 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.56 PfGW456L13_1747 Dihydroorotase (EC 3.5.2.3) — —
Pseudomonas fluorescens FW300-N2C3 0.56 AO356_02610 dihydroorotate dehydrogenase (quinone) 0.55 AO356_18315 dihydroorotase — —
Pseudomonas sp. S08-1 0.55 OH686_03120 dihydroorotate dehydrogenase (fumarate) 0.52 OH686_03940 dihydroorotase, homodimeric type — —
Dechlorosoma suillum PS 0.55 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 0.52 Dsui_0250 dihydroorotase, homodimeric type — —
Kangiella aquimarina DSM 16071 0.55 B158DRAFT_2228 dihydroorotate oxidase A (EC 1.3.3.1) 0.52 B158DRAFT_1241 dihydroorotase (EC 3.5.2.3) — —
Paraburkholderia bryophila 376MFSha3.1 0.55 H281DRAFT_00743 dihydroorotate oxidase A 0.51 H281DRAFT_04265 dihydroorotase — —
Pseudomonas stutzeri RCH2 0.55 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 0.54 Psest_3123 dihydroorotase, homodimeric type 0.91 1
Ralstonia sp. UNC404CL21Col 0.54 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase 0.53 ABZR87_RS07550 dihydroorotase — —
Pseudomonas putida KT2440 0.54 PP_2095 Dihydroorotate dehydrogenase (quinone) 0.55 PP_1086 dihydroorotase — —
Ralstonia solanacearum IBSBF1503 0.54 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase 0.54 RALBFv3_RS11590 dihydroorotase — —
Ralstonia solanacearum UW163 0.54 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase 0.54 UW163_RS01995 dihydroorotase — —
Ralstonia solanacearum GMI1000 0.53 RS_RS08160 dihydroorotate dehydrogenase (quinone) 0.53 RS_RS02420 dihydroorotase — —
Ralstonia solanacearum PSI07 0.53 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase 0.54 RPSI07_RS21625 dihydroorotase — —
Acinetobacter radioresistens SK82 0.53 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) 0.52 MPMX26_02262 Dihydroorotase — —
Herbaspirillum seropedicae SmR1 0.52 HSERO_RS16155 dihydroorotate dehydrogenase 0.54 HSERO_RS19235 dihydroorotase — —
Cupriavidus basilensis FW507-4G11 0.51 RR42_RS07465 dihydroorotate dehydrogenase 0.54 RR42_RS02610 dihydroorotase — —
Acidovorax sp. GW101-3H11 0.51 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.53 Ac3H11_1963 Dihydroorotase (EC 3.5.2.3) — —
Castellaniella sp019104865 MT123 0.50 ABCV34_RS07790 quinone-dependent dihydroorotate dehydrogenase 0.49 ABCV34_RS09730 dihydroorotase — —
Rhodanobacter denitrificans MT42 0.50 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase 0.48 LRK55_RS10600 dihydroorotase — —
Rhodanobacter denitrificans FW104-10B01 0.49 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase 0.48 LRK54_RS10900 dihydroorotase — —
Variovorax sp. SCN45 0.49 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) 0.59 GFF125 Dihydroorotase (EC 3.5.2.3) — —
Rhodanobacter sp. FW510-T8 0.48 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase 0.47 OKGIIK_12970 pyrC dihydroorotase — —
Variovorax sp. OAS795 0.48 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase 0.51 ABID97_RS06040 dihydroorotase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.47 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.52 GFF523 Dihydroorotase (EC 3.5.2.3) 0.98 3
Marinobacter adhaerens HP15 0.47 HP15_1377 dihydroorotate dehydrogenase 0.56 HP15_1216 dihydroorotase, homodimeric type 0.78 2
Sinorhizobium meliloti 1021 0.40 SMc02245 dihydroorotate dehydrogenase 2 0.53 SMc02166 dihydroorotase 0.96 1
Agrobacterium fabrum C58 0.40 Atu0486 dihydroorotate dehydrogenase 0.52 Atu0399 dihydroorotase 0.92 4
Rhizobium sp. OAE497 0.38 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase 0.51 ABIE40_RS02105 dihydroorotase — —
Azospirillum sp. SherDot2 0.37 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) 0.57 MPMX19_01633 Dihydroorotase — —
Azospirillum brasilense Sp245 0.36 AZOBR_RS13520 dihydroorotate dehydrogenase 0.57 AZOBR_RS04460 dihydroorotase 0.83 1
Phaeobacter inhibens DSM 17395 0.33 PGA1_c12150 dihydroorotate dehydrogenase PyrD 0.51 PGA1_c10910 dihydroorotase PyrC 0.97 1
Dinoroseobacter shibae DFL-12 0.32 Dshi_0847 Dihydroorotate oxidase (RefSeq) 0.50 Dshi_2371 dihydroorotase, homodimeric type (RefSeq) 0.94 1

Not shown: 18 genomes with orthologs for b0945 only; 0 genomes with orthologs for b1062 only