| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_1040 | | FolM Alternative dihydrofolate reductase 1 | insig. | 100 | 100 |
| o | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4977 | | FolM Alternative dihydrofolate reductase 1 | sig. | 91 | 100 |
| o | Pseudomonas sp. DMC3 | GFF1861 | | Dihydromonapterin reductase | cofit | 87 | 100 |
| o | Pseudomonas fluorescens FW300-N2E3 | AO353_04955 | | dihydrofolate reductase | sig. | 89 | 100 |
| o | Pseudomonas fluorescens FW300-N2C3 | AO356_16745 | | dihydrofolate reductase | sig. | 84 | 100 |
| o | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_5274 | | FolM Alternative dihydrofolate reductase 1 | strong | 84 | 100 |
| o | Pseudomonas sp. RS175 | PFR28_00208 | | Dihydromonapterin reductase | strong | 83 | 100 |
| o | Pseudomonas fluorescens SBW25 | PFLU_RS25305 | | dihydromonapterin reductase | strong | 82 | 100 |
| o | Pseudomonas fluorescens SBW25-INTG | PFLU_RS25305 | | dihydromonapterin reductase | strong | 82 | 100 |
| o | Pseudomonas simiae WCS417 | PS417_23490 | | dihydrofolate reductase | insig. | 81 | 100 |
| o | Pseudomonas lactucae CFBP13502 | GEMAOFIL_04842 | | Dihydromonapterin reductase | cofit | 80 | 100 |
| o | Pseudomonas aeruginosa PA14 | IKLFDK_17640 | | dihydromonapterin reductase | insig. | 77 | 98 |
| o | Pseudomonas syringae pv. syringae B728a | Psyr_1021 | | Short-chain dehydrogenase/reductase SDR | sig. | 76 | 100 |
| o | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1021 | | Short-chain dehydrogenase/reductase SDR | insig. | 76 | 100 |
| o | Pseudomonas stutzeri RCH2 | Psest_3204 | | Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) | strong | 75 | 97 |
| o | Pseudomonas sp. S08-1 | OH686_18770 | | FolM Alternative dihydrofolate reductase 1 | cofit | 75 | 97 |
| o | Pseudomonas segetis P6 | MPMX49_03673 | | Dihydromonapterin reductase | insig. | 70 | 100 |
| o | Marinobacter adhaerens HP15 | HP15_3719 | | short-chain dehydrogenase/reductase SDR | insig. | 51 | 97 |
| o | Klebsiella pneumoniae MKP103 | KDGMDA_20970 | | dihydromonapterin reductase | insig. | 51 | 97 |
| o | Enterobacter asburiae PDN3 | EX28DRAFT_1547 | | Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) | insig. | 51 | 97 |
| o | Alteromonas macleodii MIT1002 | MIT1002_03759 | | Dihydrofolate reductase FolM | insig. | 49 | 98 |
| o | Klebsiella michiganensis M5al | BWI76_RS16230 | | dihydromonapterin reductase | insig. | 49 | 97 |
| o | Enterobacter sp. TBS_079 | MPMX20_02028 | | Dihydromonapterin reductase | sig. | 52 | 97 |
| o | Shewanella oneidensis MR-1 | SO0772 | | oxidoreductase, short chain dehydrogenase/reductase family (NCBI ptt file) | sig. | 47 | 98 |
| o | Pectobacterium carotovorum WPP14 | HER17_RS09720 | | dihydromonapterin reductase | insig. | 46 | 100 |
| o | Shewanella sp. ANA-3 | Shewana3_3507 | | short chain dehydrogenase (RefSeq) | sig. | 47 | 98 |
| o | Serratia liquefaciens MT49 | IAI46_13295 | | dihydromonapterin reductase | insig. | 46 | 99 |
| o | Escherichia coli ECOR27 | NOLOHH_18180 | folM | dihydromonapterin reductase | no data | 46 | 97 |
| o | Escherichia coli ECRC62 | BNILDI_16970 | folM | dihydromonapterin reductase | insig. | 46 | 97 |
| o | Escherichia coli BL21 | ECD_01575 | | dihydromonapterin reductase, NADPH-dependent; dihydrofolate reductase isozyme | insig. | 46 | 97 |
| o | Escherichia coli ECRC100 | OKFHMN_27675 | folM | dihydromonapterin reductase | no data | 46 | 97 |
| o | Escherichia coli ECRC101 | MCAODC_17735 | folM | dihydromonapterin reductase | insig. | 46 | 97 |
| o | Escherichia coli ECRC102 | NIAGMN_00400 | folM | dihydromonapterin reductase | insig. | 46 | 97 |
| o | Escherichia coli ECRC98 | JDDGAC_02265 | folM | dihydromonapterin reductase | insig. | 46 | 97 |
| o | Escherichia coli ECRC99 | KEDOAH_00430 | folM | dihydromonapterin reductase | no data | 46 | 97 |
| o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_02120 | | Dihydromonapterin reductase | insig. | 46 | 97 |
| o | Escherichia coli BW25113 | b1606 | folM | short chain dehydrogenase (NCBI) | strong | 46 | 97 |
| o | Escherichia coli Nissle 1917 | ECOLIN_RS08970 | | dihydromonapterin reductase | no data | 46 | 97 |
| o | Escherichia fergusonii Becca | EFB2_02386 | | Dihydromonapterin reductase | insig. | 46 | 97 |
| o | Escherichia coli ECOR38 | HEPCGN_06050 | folM | dihydromonapterin reductase | insig. | 46 | 97 |
| o | Shewanella loihica PV-4 | Shew_0048 | | short chain dehydrogenase (RefSeq) | insig. | 46 | 97 |
| o | Pseudomonas sp. SVBP6 | COO64_RS03570 | folM | dihydromonapterin reductase | insig. | 45 | 98 |
| o | Pseudomonas sp. BP01 | JOY50_RS15610 | folM | dihydromonapterin reductase | insig. | 44 | 98 |
| o | Pseudomonas putida KT2440 | PP_4632 | | dihydrofolate reductase / dihydromonapterin reductase | strong | 43 | 98 |
| | Marinobacter adhaerens HP15 | HP15_67 | | short-chain dehydrogenase/reductase SDR | insig. | 54 | 56 |
| o | Azospirillum brasilense Sp245 | AZOBR_RS00495 | | dihydrofolate reductase folM | insig. | 41 | 97 |
| | Marinobacter adhaerens HP15 | HP15_2995 | | short-chain dehydrogenase/reductase SDR | insig. | 31 | 100 |
| | Methylophilus sp. DMC18 | GFF1543 | | 3-oxoacyl-[acyl-carrier-protein] reductase FabG | cofit | 31 | 97 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS07040 | | pteridine reductase | strong | 32 | 95 |
| | Dechlorosoma suillum PS | Dsui_0694 | | dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein | insig. | 31 | 96 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS07310 | | pteridine reductase | strong | 32 | 95 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_16340 | | pteridine reductase | cofit | 31 | 95 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.934.1 | | FolM Alternative dihydrofolate reductase 1 | insig. | 32 | 100 |
| | Lysobacter sp. OAE881 | ABIE51_RS19105 | | pteridine reductase | strong | 31 | 97 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS01100 | | pteridine reductase | cofit | 31 | 95 |
| | Azospirillum brasilense Sp245 | AZOBR_RS08970 | | short-chain dehydrogenase | sig. | 31 | 96 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1630 | | FolM Alternative dihydrofolate reductase 1 | cofit | 29 | 97 |
| | Pseudomonas putida KT2440 | PP_2002 | | putative enzyme | insig. | 29 | 95 |
| | Agrobacterium fabrum C58 | Atu1130 | | dehydrogenase | sig. | 29 | 97 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS12780 | | pteridine reductase | strong | 29 | 96 |
| | Pseudomonas sp. BP01 | JOY50_RS16555 | | SDR family oxidoreductase | insig. | 29 | 95 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_1670 | | Short-chain dehydrogenase/reductase SDR | insig. | 29 | 95 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1670 | | Short-chain dehydrogenase/reductase SDR | insig. | 29 | 95 |
| | Azospirillum sp. SherDot2 | MPMX19_01069 | | 3-oxoacyl-[acyl-carrier-protein] reductase FabG | insig. | 30 | 96 |
| | Pseudomonas sp. SVBP6 | COO64_RS05590 | | SDR family oxidoreductase | insig. | 30 | 97 |
| | Variovorax sp. OAS795 | ABID97_RS06515 | | SDR family oxidoreductase | strong | 29 | 97 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS20505 | | SDR family oxidoreductase | insig. | 28 | 97 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS20505 | | SDR family oxidoreductase | sig. | 28 | 97 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_1819 | | FolM Alternative dihydrofolate reductase 1 | sig. | 29 | 97 |
| | Rhizobium sp. OAE497 | ABIE40_RS26290 | | SDR family oxidoreductase | insig. | 29 | 97 |
| | Rhodospirillum rubrum S1H | Rru_A2218 | | Short-chain dehydrogenase/reductase SDR (NCBI) | no data | 30 | 96 |
| | Ralstonia solanacearum GMI1000 | RS_RS18610 | | 3-oxoacyl-ACP reductase FabG | insig. | 30 | 95 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_05822 | | NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family | sig. | 28 | 97 |
| | Pseudomonas sp. DMC3 | GFF800 | | Galactitol 2-dehydrogenase | cofit | 28 | 97 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_3933 | | Oxidoreductase, short chain dehydrogenase/reductase family | insig. | 29 | 97 |
| | Variovorax sp. SCN45 | GFF7306 | | FolM Alternative dihydrofolate reductase 1 | cofit | 29 | 97 |
| | Alteromonas macleodii MIT1002 | MIT1002_01601 | | 3-oxoacyl-[acyl-carrier-protein] reductase FabG | sig. | 28 | 99 |
| | Pseudomonas sp. RS175 | PFR28_02809 | | Glucose 1-dehydrogenase 1 | insig. | 29 | 97 |
| | Dinoroseobacter shibae DFL-12 | Dshi_0643 | | short-chain dehydrogenase/reductase SDR (RefSeq) | no data | 29 | 99 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_78 | | Oxidoreductase, short chain dehydrogenase/reductase family | insig. | 28 | 97 |
| o | Shewanella amazonensis SB2B | Sama_1764 | | short-chain dehydrogenase/reductase SDR (RefSeq) | sig. | 29 | 95 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_21475 | | oxidoreductase | insig. | 28 | 97 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_2954 | | Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) | insig. | 29 | 95 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_03933 | | Galactitol 2-dehydrogenase | cofit | 27 | 97 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_20700 | | oxidoreductase | insig. | 28 | 97 |
| | Shewanella loihica PV-4 | Shew_2034 | | short-chain dehydrogenase/reductase SDR (RefSeq) | insig. | 27 | 95 |
| | Dechlorosoma suillum PS | Dsui_3259 | | dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein | cofit | 28 | 96 |
| | Pseudomonas sp. S08-1 | OH686_04500 | | Oxidoreductase, short-chain dehydrogenase/reductase family | insig. | 27 | 96 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS15920 | | SDR family oxidoreductase | cofit | 26 | 95 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS06495 | | glucose-1-dehydrogenase | insig. | 28 | 99 |
| | Caulobacter crescentus NA1000 | CCNA_00422 | | SDR pteridine reductase | strong | 30 | 100 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_00422 | | SDR pteridine reductase | cofit | 30 | 100 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c02870 | | short chain dehydrogenase | insig. | 29 | 96 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_02595 | | oxidoreductase | insig. | 25 | 97 |
| | Sinorhizobium meliloti 1021 | SMc00603 | | short chain dehydrogenase | insig. | 29 | 100 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_15400 | | short-chain dehydrogenase | insig. | 26 | 95 |
| | Sphingobium sp. HT1-2 | GFF1574 | | FolM Alternative dihydrofolate reductase 1 | cofit | 34 | 58 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS22000 | | short-chain dehydrogenase | sig. | 29 | 99 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2735 | | FolM Alternative dihydrofolate reductase 1 | insig. | 30 | 88 |
| | Rhizobium sp. OAE497 | ABIE40_RS06505 | | SDR family oxidoreductase | cofit | 27 | 96 |