| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_14715 | | Biotin synthase | insig. | 100 | 100 |
| o | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS00510 | | class I SAM-dependent methyltransferase | insig. | 84 | 96 |
| o | Rhodanobacter denitrificans MT42 | LRK55_RS04905 | | class I SAM-dependent methyltransferase | insig. | 83 | 94 |
| o | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS05125 | | class I SAM-dependent methyltransferase | insig. | 83 | 94 |
| o | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS04705 | | class I SAM-dependent methyltransferase | insig. | 71 | 95 |
| o | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.3167.1 | | biotin synthesis protein | insig. | 68 | 95 |
| o | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS04375 | | class I SAM-dependent methyltransferase | insig. | 29 | 86 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS03780 | | malonyl-ACP O-methyltransferase BioC | cofit | 40 | 57 |
| | Enterobacter sp. TBS_079 | MPMX20_03533 | | Trans-aconitate 2-methyltransferase | insig. | 39 | 46 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_2743 | | Methyltransferase domain | insig. | 34 | 59 |
| | Pantoea sp. MT58 | IAI47_13520 | | malonyl-ACP O-methyltransferase BioC | insig. | 38 | 58 |
| o | Cellulophaga baltica 18 | M666_RS13145 | | class I SAM-dependent methyltransferase | insig. | 22 | 90 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03967 | | Methylase involved in ubiquinone/menaquinone biosynthesis | insig. | 28 | 74 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS07135 | | methyltransferase | insig. | 34 | 59 |
| o | Agrobacterium fabrum C58 | Atu1041 | | methyltransferase | insig. | 27 | 81 |
| | Serratia liquefaciens MT49 | IAI46_06535 | | malonyl-ACP O-methyltransferase BioC | insig. | 35 | 63 |
| | Enterobacter sp. TBS_079 | MPMX20_01405 | | Malonyl-[acyl-carrier protein] O-methyltransferase | sig. | 35 | 57 |
| | Paraburkholderia graminis OAS925 | ABIE53_003194 | | ubiquinone/menaquinone biosynthesis C-methylase UbiE | insig. | 28 | 74 |
| | Serratia liquefaciens MT49 | IAI46_19810 | | class I SAM-dependent methyltransferase | insig. | 32 | 54 |
| | Klebsiella michiganensis M5al | BWI76_RS19545 | | type 11 methyltransferase | no data | 36 | 60 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS03890 | | class I SAM-dependent methyltransferase | insig. | 29 | 58 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_0427 | | conserved hypothetical protein | insig. | 28 | 63 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_0427 | | conserved hypothetical protein | insig. | 28 | 63 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS15110 | | methyltransferase | insig. | 26 | 74 |
| | Erwinia amylovora T8 | OLJFJH_16750 | | malonyl-ACP O-methyltransferase BioC | insig. | 39 | 43 |
| | Cellulophaga baltica 18 | M666_RS08585 | | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE | no data | 23 | 67 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_248 | | FIG025233: SAM-dependent methyltransferases | insig. | 30 | 58 |
| | Pseudomonas sp. DMC3 | GFF3116 | | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | insig. | 30 | 58 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_13680 | | SAM-dependent methyltransferase | insig. | 32 | 64 |
| | Methanococcus maripaludis S2 | MMP_RS02635 | | class I SAM-dependent methyltransferase | insig. | 26 | 44 |
| | Dickeya dianthicola 67-19 | HGI48_RS08685 | | malonyl-ACP O-methyltransferase BioC | insig. | 35 | 43 |
| | Dickeya dianthicola ME23 | DZA65_RS08975 | | malonyl-ACP O-methyltransferase BioC | insig. | 35 | 43 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_3105 | | Methyltransferase domain | strong | 35 | 54 |
| o | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_00395 | | SAM-dependent methyltransferase | insig. | 28 | 82 |
| | Pectobacterium carotovorum WPP14 | HER17_RS13450 | | malonyl-ACP O-methyltransferase BioC | cofit | 37 | 46 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS24960 | | class I SAM-dependent methyltransferase | insig. | 37 | 47 |
| | Enterobacter sp. TBS_079 | MPMX20_00895 | | putative methyltransferase YcgJ | insig. | 35 | 45 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_12630 | | methyltransferase | insig. | 28 | 58 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS16515 | | methyltransferase domain-containing protein | insig. | 40 | 43 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS18760 | | glycosyltransferase | strong | 35 | 43 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_1969 | | SAM-dependent methyltransferases | insig. | 39 | 46 |
| | Marinobacter adhaerens HP15 | HP15_2483 | | protein containing methyltransferase type 11 domain | insig. | 35 | 44 |
| | Dickeya dadantii 3937 | DDA3937_RS08520 | | malonyl-ACP O-methyltransferase BioC | insig. | 33 | 50 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS10075 | | methyltransferase domain-containing protein | insig. | 38 | 46 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0606 | | transcriptional regulator, ArsR family/methyltransferase, UbiE/COQ5 family (TIGR) | strong | 38 | 43 |
| | Azospirillum sp. SherDot2 | MPMX19_03671 | | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | insig. | 37 | 47 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c29610 | | phosphatidylethanolamine N-methyltransferase PmtA | strong | 27 | 65 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2579 | | transcriptional regulator, ArsR family (RefSeq) | no data | 40 | 46 |
| | Pseudomonas sp. S08-1 | OH686_09950 | | SAM-dependent | cofit | 37 | 42 |
| | Ralstonia solanacearum GMI1000 | RS_RS18860 | | class I SAM-dependent methyltransferase | insig. | 28 | 74 |
| | Klebsiella michiganensis M5al | BWI76_RS05430 | | UbiE/COQ5 family methyltransferase | sig. | 28 | 79 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_17035 | | malonyl-ACP O-methyltransferase BioC | sig. | 41 | 42 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS25585 | | class I SAM-dependent methyltransferase | strong | 35 | 54 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS58035 | | class I SAM-dependent methyltransferase | insig. | 35 | 54 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4042 | | SAM-dependent methyltransferase YafE (UbiE paralog) | insig. | 35 | 45 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_2684 | | Methyltransferase domain | insig. | 34 | 50 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_12755 | | SAM-dependent methyltransferase | insig. | 29 | 43 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_19575 | bioC | malonyl-ACP O-methyltransferase BioC | no data | 37 | 44 |
| | Erwinia tracheiphila SCR3 | LU632_RS09140 | bioC | malonyl-ACP O-methyltransferase BioC | no data | 37 | 44 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_26120 | | SAM-dependent methyltransferase | insig. | 35 | 54 |
| | Escherichia coli BL21 | ECD_00744 | | malonyl-ACP O-methyltransferase, SAM-dependent | insig. | 35 | 51 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_02936 | | Malonyl-[acyl-carrier protein] O-methyltransferase | insig. | 35 | 51 |
| | Escherichia coli BW25113 | b0777 | bioC | predicted methltransferase, enzyme of biotin synthesis (NCBI) | sig. | 35 | 51 |
| | Paraburkholderia graminis OAS925 | ABIE53_001147 | | ubiquinone/menaquinone biosynthesis C-methylase UbiE/glycosyltransferase involved in cell wall biosynthesis/regulator of replication initiation timing | strong | 34 | 44 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS03195 | | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE | strong | 30 | 47 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS15120 | | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase | no data | 24 | 62 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_2342 | | SAM-dependent methyltransferases | strong | 38 | 46 |
| | Escherichia fergusonii Becca | EFB2_03328 | | Malonyl-[acyl-carrier protein] O-methyltransferase | insig. | 35 | 51 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS04140 | | malonyl-ACP O-methyltransferase BioC | insig. | 35 | 51 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_00450 | | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase | no data | 30 | 41 |
| | Rhodopseudomonas palustris CGA009 | TX73_006705 | | class I SAM-dependent methyltransferase | no data | 28 | 68 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_1515 | | FIG025233: SAM-dependent methyltransferases | insig. | 33 | 43 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_00644 | | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | cofit | 27 | 58 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS12670 | | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE | strong | 26 | 54 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS16755 | | bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE | strong | 26 | 55 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_21410 | | SAM-dependent methyltransferase | cofit | 34 | 49 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_09200 | | methyltransferase | insig. | 28 | 57 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS05220 | | S-adenosyl-L-methionine (SAM)-dependent methyltransferase PhcB | insig. | 35 | 46 |
| | Shewanella oneidensis MR-1 | SO1988 | | hypothetical methyltransferase (NCBI ptt file) | insig. | 29 | 44 |
| | Escherichia coli ECRC100 | OKFHMN_06390 | bioC | malonyl-ACP O-methyltransferase BioC | insig. | 40 | 41 |
| | Escherichia coli ECRC101 | MCAODC_25605 | bioC | malonyl-ACP O-methyltransferase BioC | insig. | 40 | 41 |
| | Escherichia coli ECRC102 | NIAGMN_04435 | bioC | malonyl-ACP O-methyltransferase BioC | strong | 40 | 41 |
| | Escherichia coli ECRC98 | JDDGAC_10025 | bioC | malonyl-ACP O-methyltransferase BioC | insig. | 40 | 41 |
| | Escherichia coli ECRC99 | KEDOAH_21520 | bioC | malonyl-ACP O-methyltransferase BioC | no data | 40 | 41 |
| | Pseudomonas sp. RS175 | PFR28_05026 | | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | insig. | 35 | 42 |
| | Escherichia coli ECOR38 | HEPCGN_01650 | bioC | malonyl-ACP O-methyltransferase BioC | insig. | 34 | 51 |
| | Escherichia coli ECRC62 | BNILDI_21030 | bioC | malonyl-ACP O-methyltransferase BioC | cofit | 34 | 51 |
| | Escherichia coli ECOR27 | NOLOHH_22760 | bioC | malonyl-ACP O-methyltransferase BioC | insig. | 34 | 51 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_0664 | | Methylase involved in ubiquinone/menaquinone biosynthesis | insig. | 31 | 43 |
| | Sinorhizobium meliloti 1021 | SMc01426 | | hypothetical protein | insig. | 31 | 55 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_10225 | | methyltransferase | sig. | 37 | 46 |
| | Variovorax sp. OAS795 | ABID97_RS16745 | | class I SAM-dependent methyltransferase | cofit | 36 | 44 |
| | Pectobacterium carotovorum WPP14 | HER17_RS04660 | | SAM-dependent methyltransferase | insig. | 35 | 46 |
| | Pseudomonas sp. DMC3 | GFF787 | | putative methyltransferase YcgJ | cofit | 34 | 66 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_10215 | | methyltransferase | strong | 33 | 51 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_05655 | | malonyl-[acyl-carrier protein] O-methyltransferase BioC | insig. | 33 | 48 |
| | Caulobacter crescentus NA1000 | CCNA_01922 | | SAM-dependent methyltransferase | strong | 28 | 66 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_01922 | | SAM-dependent methyltransferase | cofit | 28 | 66 |
| | Azospirillum sp. SherDot2 | MPMX19_01135 | | putative methyltransferase YcgJ | insig. | 36 | 42 |
| | Pseudomonas sp. BP01 | JOY50_RS16620 | | class I SAM-dependent methyltransferase | insig. | 36 | 48 |