| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| o | Escherichia coli BL21 | ECD_01211 | | PcnB-degradosome interaction factor; response regulator | strong | 100 | 100 |
| | Escherichia coli ECOR38 | HEPCGN_25045 | rssB | two-component system response regulator RssB | strong | 100 | 100 |
| o | Escherichia coli ECRC100 | OKFHMN_28585 | rssB | two-component system response regulator RssB | cofit | 100 | 100 |
| o | Escherichia coli ECRC101 | MCAODC_21675 | rssB | two-component system response regulator RssB | strong | 100 | 100 |
| o | Escherichia coli ECRC102 | NIAGMN_27650 | rssB | two-component system response regulator RssB | no data | 100 | 100 |
| o | Escherichia coli ECRC62 | BNILDI_18620 | rssB | two-component system response regulator RssB | strong | 100 | 100 |
| o | Escherichia coli ECRC98 | JDDGAC_05990 | rssB | two-component system response regulator RssB | strong | 100 | 100 |
| o | Escherichia coli ECRC99 | KEDOAH_25580 | rssB | two-component system response regulator RssB | no data | 100 | 100 |
| o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_02450 | | Regulator of RpoS | strong | 100 | 100 |
| o | Escherichia coli BW25113 | b1235 | rssB | response regulator of RpoS (NCBI) | strong | 100 | 100 |
| o | Escherichia fergusonii Becca | EFB2_02691 | | Regulator of RpoS | sig. | 100 | 100 |
| o | Escherichia coli ECOR27 | NOLOHH_20465 | rssB | two-component system response regulator RssB | insig. | 100 | 100 |
| o | Escherichia coli Nissle 1917 | ECOLIN_RS07475 | | two-component system response regulator RssB | no data | 100 | 100 |
| o | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF2753 | | Hnr protein | strong | 90 | 100 |
| o | Klebsiella pneumoniae MKP103 | KDGMDA_24505 | | two-component system response regulator RssB | sig. | 82 | 100 |
| o | Klebsiella michiganensis M5al | BWI76_RS17275 | | two-component system response regulator RssB | insig. | 81 | 100 |
| o | Enterobacter asburiae PDN3 | EX28DRAFT_0861 | | Response regulator receiver domain | strong | 84 | 100 |
| o | Enterobacter sp. TBS_079 | MPMX20_02593 | | Regulator of RpoS | strong | 83 | 100 |
| o | Erwinia amylovora T8 | OLJFJH_13285 | | two-component system response regulator RssB | strong | 74 | 100 |
| o | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_22690 | rssB | two-component system response regulator RssB | strong | 72 | 100 |
| o | Erwinia tracheiphila SCR3 | LU632_RS12925 | rssB | two-component system response regulator RssB | cofit | 72 | 100 |
| o | Pantoea sp. MT58 | IAI47_09025 | | two-component system response regulator RssB | no data | 72 | 100 |
| o | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS02865 | | two-component system response regulator RssB | no data | 71 | 100 |
| o | Rahnella sp. WP5 | EX31_RS10100 | | two-component system response regulator RssB | insig. | 65 | 100 |
| o | Serratia liquefaciens MT49 | IAI46_14250 | | two-component system response regulator RssB | insig. | 69 | 100 |
| o | Dickeya dianthicola 67-19 | HGI48_RS10350 | | two-component system response regulator RssB | cofit | 65 | 100 |
| o | Dickeya dianthicola ME23 | DZA65_RS10825 | | two-component system response regulator RssB | sig. | 64 | 100 |
| o | Pectobacterium carotovorum WPP14 | HER17_RS11050 | | two-component system response regulator RssB | cofit | 63 | 100 |
| o | Vibrio cholerae E7946 ATCC 55056 | CSW01_05345 | | two-component system response regulator | insig. | 31 | 96 |
| o | Pseudomonas segetis P6 | MPMX49_01910 | | Regulator of RpoS | no data | 28 | 94 |
| o | Pseudomonas aeruginosa PA14 | IKLFDK_14160 | | fused response regulator/phosphatase | no data | 28 | 96 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_60 | | Serine phosphatase RsbU, regulator of sigma subunit | no data | 31 | 82 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS07795 | | SpoIIE family protein phosphatase | no data | 31 | 81 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS07795 | | SpoIIE family protein phosphatase | no data | 31 | 81 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2260 | | Serine phosphatase RsbU, regulator of sigma subunit | no data | 30 | 82 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_02185 | | chemotaxis protein CheY | no data | 30 | 82 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_1912 | | Response regulator receiver:Stage II sporulation E | no data | 27 | 90 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1912 | | Response regulator receiver:Stage II sporulation E | no data | 27 | 90 |
| | Pseudomonas sp. RS175 | PFR28_01140 | | Regulator of RpoS | no data | 31 | 82 |
| | Pseudomonas putida KT2440 | PP_2165 | | Response regulator | no data | 29 | 90 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_01676 | | Regulator of RpoS | no data | 31 | 81 |
| | Pseudomonas sp. BP01 | JOY50_RS25185 | rssB | two-component system response regulator RssB | no data | 29 | 90 |
| | Pseudomonas simiae WCS417 | PS417_07720 | | chemotaxis protein CheY | no data | 31 | 81 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4011 | | Serine phosphatase RsbU, regulator of sigma subunit | no data | 30 | 82 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_00320 | | chemotaxis protein CheY | no data | 30 | 81 |
| | Pseudomonas sp. S08-1 | OH686_22730 | | Serine phosphatase RsbU, regulator of sigma subunit | no data | 28 | 90 |
| | Pseudomonas stutzeri RCH2 | Psest_2710 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | no data | 29 | 87 |
| | Pseudomonas sp. DMC3 | GFF1302 | | Regulator of RpoS | no data | 28 | 82 |
| | Shewanella loihica PV-4 | Shew_1396 | | response regulator receiver protein (RefSeq) | insig. | 26 | 74 |
| | Pseudomonas sp. SVBP6 | COO64_RS09545 | rssB | two-component system response regulator RssB | no data | 26 | 88 |
| | Shewanella oneidensis MR-1 | SO3196 | | response regulator (NCBI ptt file) | strong | 27 | 74 |
| | Shewanella sp. ANA-3 | Shewana3_1372 | | response regulator receiver protein (RefSeq) | strong | 26 | 74 |
| | Shewanella amazonensis SB2B | Sama_2267 | | response regulator receiver protein (RefSeq) | strong | 29 | 65 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_3878 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | cofit | 43 | 31 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_1146 | | Serine phosphatase RsbU, regulator of sigma subunit | insig. | 29 | 65 |
| | Ralstonia solanacearum GMI1000 | RS_RS18655 | | DNA-binding response regulator | sig. | 42 | 30 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS21895 | | DNA-binding response regulator | insig. | 41 | 30 |
| | Ralstonia solanacearum UW163 | UW163_RS17290 | | DNA-binding response regulator | insig. | 41 | 30 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS19780 | | chemotaxis protein CheY | strong | 41 | 31 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS12135 | | response regulator | cofit | 39 | 30 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0482 | | sensory box histidine kinase/response regulator (TIGR) | insig. | 35 | 34 |
| | Mycobacterium tuberculosis H37Rv | Rv0981 | | Mycobacterial persistence regulator MRPA (two component response transcriptional regulatory protein) | insig. | 36 | 30 |
| | Dickeya dadantii 3937 | DDA3937_RS07165 | | response regulator transcription factor | insig. | 40 | 30 |
| | Escherichia fergusonii Becca | EFB2_01635 | | Regulatory protein AtoC | insig. | 38 | 32 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS12965 | | acetoacetate metabolism transcriptional regulator AtoC | no data | 38 | 32 |
| | Escherichia coli BL21 | ECD_02147 | | fused response regulator of ato operon, in two-component system with AtoS: response regulator/sigma54 interaction protein | insig. | 38 | 33 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01490 | | Regulatory protein AtoC | insig. | 38 | 33 |
| | Escherichia coli BW25113 | b2220 | atoC | fused response regulator of ato operon, in two-component system with AtoS: response regulator/sigma54 interaction protein (NCBI) | insig. | 38 | 33 |
| | Escherichia coli ECOR38 | HEPCGN_22430 | atoC | acetoacetate metabolism transcriptional regulator AtoC | insig. | 38 | 33 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_5122 | | Type IV fimbriae expression regulatory protein PilR | insig. | 40 | 35 |
| | Rhodospirillum rubrum S1H | Rru_A2929 | | Two component Transcriptional regulator, Winged helix family (NCBI) | cofit | 38 | 32 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_3074 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | cofit | 32 | 39 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_15905 | | transcriptional regulator | insig. | 40 | 35 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_1453 | rpaB | two component transcriptional regulator, winged helix family | no data | 34 | 30 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS12575 | | response regulator | sig. | 33 | 32 |
| | Ralstonia solanacearum GMI1000 | RS_RS03360 | | response regulator | insig. | 33 | 32 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS20680 | | response regulator | insig. | 33 | 32 |
| | Ralstonia solanacearum UW163 | UW163_RS00990 | | response regulator | insig. | 33 | 32 |
| | Fusobacterium nucleatum SB010 | HUW76_07205 | | response regulator transcription factor | strong | 36 | 30 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0732 | | two-component system response regulator (NCBI ptt file) | no data | 34 | 30 |
| | Serratia liquefaciens MT49 | IAI46_17870 | | transcriptional regulator TctD | insig. | 37 | 36 |
| | Shewanella amazonensis SB2B | Sama_1718 | | response regulator receiver protein (RefSeq) | strong | 39 | 31 |
| | Pseudomonas sp. RS175 | PFR28_03751 | | Regulatory protein AtoC | insig. | 40 | 35 |
| | Shewanella sp. ANA-3 | Shewana3_1959 | | two component transcriptional regulator (RefSeq) | insig. | 37 | 30 |
| | Azospirillum sp. SherDot2 | MPMX19_03749 | | KDP operon transcriptional regulatory protein KdpE | insig. | 32 | 42 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS04655 | | DNA-binding response regulator | strong | 39 | 30 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_2818 | | Type IV fimbriae expression regulatory protein PilR | insig. | 39 | 35 |
| | Dickeya dianthicola ME23 | DZA65_RS15390 | | transcriptional regulator TctD | insig. | 38 | 31 |
| | Dickeya dianthicola 67-19 | HGI48_RS14455 | | transcriptional regulator TctD | insig. | 36 | 39 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS15035 | | response regulator transcription factor | insig. | 33 | 30 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS14995 | | response regulator transcription factor | insig. | 39 | 30 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS14995 | | response regulator transcription factor | insig. | 39 | 30 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_04380 | | response regulator | strong | 32 | 45 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS11370 | | response regulator transcription factor | no data | 33 | 30 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS08575 | | response regulator | insig. | 32 | 32 |
| | Pseudomonas simiae WCS417 | PS417_10855 | | chemotaxis protein CheY | insig. | 38 | 30 |
| | Marinobacter adhaerens HP15 | HP15_523 | | two component, sigma54 specific, transcriptional regulator, Fis family | strong | 39 | 34 |
| | Pseudomonas sp. RS175 | PFR28_04227 | | Sensor histidine kinase RcsC | insig. | 35 | 31 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS20435 | | heavy metal response regulator transcription factor | insig. | 40 | 30 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS20435 | | heavy metal response regulator transcription factor | insig. | 40 | 30 |