Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| Phaeobacter inhibens DSM 17395 | PGA1_c25710 | | putative N-methylproline demethylase StcD | insig. | 100 | 100 |
o | Sinorhizobium meliloti 1021 | SM_b21570 | | NADH-dependent oxidase | insig. | 70 | 100 |
o | Pseudomonas putida KT2440 | PP_4753 | | putative N-methylproline demethylase | insig. | 69 | 100 |
o | Agrobacterium fabrum C58 | Atu2538 | | N-methylproline demethylase | insig. | 70 | 100 |
o | Pseudomonas fluorescens FW300-N2C3 | AO356_21840 | | N-methylproline demethylase | insig. | 68 | 100 |
o | Pseudomonas simiae WCS417 | PS417_10820 | | N-methylproline demethylase | insig. | 68 | 100 |
o | Rhizobium sp. OAE497 | ABIE40_RS05250 | | NADH:flavin oxidoreductase | insig. | 58 | 99 |
| Paraburkholderia sabiae LMG 24235 | QEN71_RS36480 | | FAD-dependent oxidoreductase | insig. | 65 | 75 |
o | Azospirillum sp. SherDot2 | MPMX19_04721 | | putative N-methylproline demethylase | insig. | 50 | 100 |
o | Pseudomonas sp. RS175 | PFR28_04147 | | putative N-methylproline demethylase | strong | 42 | 100 |
| Pseudomonas simiae WCS417 | PS417_26240 | | N-methylproline demethylase | insig. | 42 | 100 |
| Pseudomonas fluorescens FW300-N2C3 | AO356_13905 | | N-methylproline demethylase | strong | 42 | 100 |
o | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_4702 | | DgcA Dimethylglycine demethylase subunit A | strong | 42 | 100 |
o | Pseudomonas fluorescens SBW25 | PFLU_RS27885 | | dimethylglycine demethylation protein DgcA | insig. | 42 | 100 |
o | Pseudomonas fluorescens SBW25-INTG | PFLU_RS27885 | | dimethylglycine demethylation protein DgcA | strong | 42 | 100 |
o | Paraburkholderia graminis OAS925 | ABIE53_006135 | | 2,4-dienoyl-CoA reductase-like NADH-dependent reductase (Old Yellow Enzyme family)/thioredoxin reductase | strong | 42 | 99 |
| Pseudomonas putida KT2440 | PP_0310 | | putative dimethylglycine dehydrogenase subunit | strong | 43 | 100 |
o | Pseudomonas fluorescens GW456-L13 | PfGW456L13_1103 | | DgcA Dimethylglycine demethylase subunit A | insig. | 42 | 100 |
o | Burkholderia phytofirmans PsJN | BPHYT_RS25195 | | N-methylproline demethylase | no data | 42 | 99 |
o | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02471 | | 2,4-dienoyl-CoA reductase | strong | 42 | 99 |
| Paraburkholderia sabiae LMG 24235 | QEN71_RS08325 | | NADH:flavin oxidoreductase | insig. | 42 | 99 |
o | Pseudomonas syringae pv. syringae B728a | Psyr_4782 | | NADH:flavin oxidoreductase/NADH oxidase | sig. | 41 | 100 |
o | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_4782 | | NADH:flavin oxidoreductase/NADH oxidase | insig. | 41 | 100 |
o | Ralstonia solanacearum GMI1000 | RS_RS17475 | | FAD-dependent oxidoreductase | insig. | 43 | 99 |
o | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_2439 | | DgcA Dimethylglycine demethylase subunit A | strong | 41 | 100 |
o | Pseudomonas fluorescens FW300-N2E3 | AO353_07710 | | DgcA Dimethylglycine demethylase subunit A (from data) | strong | 41 | 100 |
| Pseudomonas fluorescens GW456-L13 | PfGW456L13_3218 | | 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) | insig. | 29 | 99 |
| Pseudomonas putida KT2440 | PP_2869 | | Oxidoreductase, FMN-binding | insig. | 32 | 79 |
| Pseudomonas fluorescens FW300-N2E3 | AO353_24795 | | oxidoreductase | insig. | 29 | 99 |
| Acinetobacter radioresistens SK82 | MPMX26_02255 | | 2,4-dienoyl-CoA reductase | no data | 32 | 73 |
| Enterobacter sp. TBS_079 | MPMX20_03994 | | 2,4-dienoyl-CoA reductase | insig. | 33 | 75 |
| Paraburkholderia graminis OAS925 | ABIE53_002850 | | 2,4-dienoyl-CoA reductase (NADPH2) | insig. | 31 | 75 |
| Pseudomonas fluorescens FW300-N2E3 | AO353_20220 | | 2,4-dienoyl-CoA reductase | insig. | 32 | 73 |
| Pseudomonas fluorescens GW456-L13 | PfGW456L13_2567 | | 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) | insig. | 31 | 73 |
| Paraburkholderia sabiae LMG 24235 | QEN71_RS05490 | | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 32 | 75 |
| Pseudomonas sp. RS175 | PFR28_01236 | | 2,4-dienoyl-CoA reductase | insig. | 31 | 73 |
| Enterobacter asburiae PDN3 | EX28DRAFT_3152 | | NADH:flavin oxidoreductases, Old Yellow Enzyme family | insig. | 32 | 75 |
| Klebsiella michiganensis M5al | BWI76_RS24675 | | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 33 | 75 |
| Burkholderia phytofirmans PsJN | BPHYT_RS13185 | | 2,4-dienoyl-CoA reductase | sig. | 31 | 75 |
| Escherichia coli ECOR38 | HEPCGN_17420 | fadH | NADPH-dependent 2,4-dienoyl-CoA reductase | cofit | 31 | 75 |
| Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_3955 | | 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) | insig. | 31 | 73 |
| Escherichia coli ECRC101 | OKFHMN_18575 | fadH | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 31 | 75 |
| Escherichia coli ECRC102 | NIAGMN_16340 | fadH | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 31 | 75 |
| Escherichia coli ECRC98 | JDDGAC_22210 | fadH | NADPH-dependent 2,4-dienoyl-CoA reductase | no data | 31 | 75 |
| Escherichia coli ECRC99 | KEDOAH_09570 | fadH | NADPH-dependent 2,4-dienoyl-CoA reductase | no data | 31 | 75 |
| Pseudomonas fluorescens FW300-N2C3 | AO356_01700 | | 2,4-dienoyl-CoA reductase | insig. | 31 | 73 |
| Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2209 | | 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) | insig. | 31 | 73 |
| Escherichia coli ECRC101 | MCAODC_09090 | fadH | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 31 | 75 |
| Escherichia fergusonii Becca | EFB2_00730 | | 2,4-dienoyl-CoA reductase | insig. | 31 | 75 |
| Escherichia coli Nissle 1917 | ECOLIN_RS17775 | | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 31 | 75 |
| Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_00403 | | 2,4-dienoyl-CoA reductase (EC 1.3.1.34) | insig. | 31 | 75 |
| Kangiella aquimarina DSM 16071 | B158DRAFT_1579 | | 2,4-dienoyl-CoA reductase (EC 1.3.1.34) | insig. | 30 | 71 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3185 | | 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) | insig. | 32 | 71 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00621 | | 2,4-dienoyl-CoA reductase | insig. | 31 | 75 |
| Escherichia coli ECOR27 | NOLOHH_10370 | fadH | NADPH-dependent 2,4-dienoyl-CoA reductase | cofit | 31 | 75 |
| Escherichia coli ECRC62 | BNILDI_01145 | fadH | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 31 | 75 |
| Phaeobacter inhibens DSM 17395 | PGA1_c29100 | | 2,4-dienoyl-CoA reductase FadH | sig. | 30 | 73 |
| Escherichia coli BL21 | ECD_02950 | | 2,4-dienoyl-CoA reductase, NADH and FMN-linked | insig. | 31 | 75 |
| Escherichia coli BW25113 | b3081 | fadH | 2,4-dienoyl-CoA reductase, NADH and FMN-linked (NCBI) | insig. | 31 | 75 |
| Serratia liquefaciens MT49 | IAI46_22180 | | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 33 | 75 |
| Dinoroseobacter shibae DFL-12 | Dshi_0125 | | NADH:flavin oxidoreductase/NADH oxidase (RefSeq) | insig. | 33 | 73 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3857 | | 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) | insig. | 28 | 99 |
| Shewanella oneidensis MR-1 | SO2419 | | 2,4-dienoyl-CoA reductase, putative (NCBI ptt file) | insig. | 28 | 76 |
| Dyella japonica UNC79MFTsu3.2 | ABZR86_RS05580 | | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 31 | 74 |
| Shewanella sp. ANA-3 | Shewana3_1965 | | 2,4-dienoyl-CoA reductase (RefSeq) | insig. | 28 | 76 |
| Vibrio cholerae E7946 ATCC 55056 | CSW01_09945 | | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 31 | 73 |
| Pectobacterium carotovorum WPP14 | HER17_RS18675 | | NADPH-dependent 2,4-dienoyl-CoA reductase | cofit | 30 | 74 |
| Acidovorax sp. GW101-3H11 | Ac3H11_340 | | 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) | insig. | 29 | 70 |
| Acidovorax sp. GW101-3H11 | Ac3H11_1018 | | 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) | insig. | 31 | 73 |
| Shewanella amazonensis SB2B | Sama_1724 | | NADH:flavin oxidoreductase/NADH oxidase (RefSeq) | insig. | 29 | 74 |
| Pseudomonas sp. S08-1 | OH686_04325 | | 2,4-dienoyl-CoA reductase [NADPH] | cofit | 32 | 74 |
| Alteromonas macleodii MIT1002 | MIT1002_02566 | | 2,4-dienoyl-CoA reductase [NADPH] | insig. | 30 | 71 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF977 | | 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) | insig. | 31 | 74 |
| Acinetobacter radioresistens SK82 | MPMX26_01687 | | 2,4-dienoyl-CoA reductase | sig. | 28 | 71 |
| Shewanella loihica PV-4 | Shew_1942 | | NADH:flavin oxidoreductase/NADH oxidase (RefSeq) | insig. | 29 | 74 |
| Marinobacter adhaerens HP15 | HP15_1058 | | 2,4-dienoyl-CoA reductase | insig. | 30 | 73 |
| Alteromonas macleodii MIT1002 | MIT1002_03065 | | 2,4-dienoyl-CoA reductase [NADPH] | insig. | 29 | 74 |
| Pseudomonas fluorescens SBW25 | PFLU_RS19095 | | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 31 | 73 |
| Pseudomonas fluorescens SBW25-INTG | PFLU_RS19095 | | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 31 | 73 |
| Pantoea sp. MT58 | IAI47_02955 | | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 29 | 71 |
| Magnetospirillum magneticum AMB-1 | AMB_RS17475 | | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 29 | 76 |
| Rhodanobacter sp. FW510-T8 | OKGIIK_07280 | fadH | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 29 | 74 |
| Pseudomonas simiae WCS417 | PS417_17165 | | 2,4-dienoyl-CoA reductase | insig. | 32 | 73 |
| Ralstonia sp. UNC404CL21Col | ABZR87_RS19455 | | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 30 | 73 |
| Azospirillum sp. SherDot2 | MPMX19_05811 | | 2,4-dienoyl-CoA reductase | insig. | 30 | 74 |
| Rhodanobacter denitrificans MT42 | LRK55_RS17875 | | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 29 | 73 |
| Rhodanobacter denitrificans FW104-10B01 | LRK54_RS18020 | | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 29 | 73 |
| Rahnella sp. WP5 | EX31_RS08345 | | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 31 | 70 |
| Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.4097.1 | | 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) | insig. | 30 | 76 |
| Pseudomonas putida KT2440 | PP_2008 | | 2,4-dienoyl-CoA reductase | insig. | 31 | 73 |
| Mycobacterium tuberculosis H37Rv | Rv1175c | | Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) | insig. | 30 | 74 |
| Rhodanobacter sp. FW510-T8 | OKGIIK_11360 | | NADH:flavin oxidoreductase | insig. | 30 | 80 |
| Rhodanobacter denitrificans FW104-10B01 | LRK54_RS04535 | | FAD-dependent oxidoreductase | insig. | 28 | 91 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_2854 | | NADH:flavin oxidoreductases, Old Yellow Enzyme family | insig. | 31 | 73 |
| Phaeobacter inhibens DSM 17395 | PGA1_c25330 | | 2,4-dienoyl-CoA reductase [NADPH] | insig. | 29 | 76 |
| Rhodanobacter denitrificans MT42 | LRK55_RS04310 | | FAD-dependent oxidoreductase | insig. | 28 | 91 |
| Pseudomonas stutzeri RCH2 | Psest_2554 | | NADH:flavin oxidoreductases, Old Yellow Enzyme family | insig. | 30 | 70 |
| Pseudomonas syringae pv. syringae B728a | Psyr_1675 | | 2,4-dienoyl-CoA reductase | insig. | 30 | 73 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1675 | | 2,4-dienoyl-CoA reductase | insig. | 30 | 73 |
| Lysobacter sp. OAE881 | ABIE51_RS06045 | | NADPH-dependent 2,4-dienoyl-CoA reductase | insig. | 30 | 76 |