| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Mycobacterium tuberculosis H37Rv | 1.0 | Rv3433c | | Conserved protein | 1.0 | Rv2388c | | Probable oxygen-independent coproporphyrinogen III oxidase HemN (coproporphyrinogenase) (coprogen oxidase) | 0.38 | 14 |
| Rhizobium sp. OAE497 | 0.19 | ABIE40_RS09345 | | NAD(P)H-hydrate dehydratase | 0.27 | ABIE40_RS01625 | | radical SAM family heme chaperone HemW | — | — |
| Bosea sp. OAE506 | 0.19 | ABIE41_RS16885 | | NAD(P)H-hydrate dehydratase | 0.28 | ABIE41_RS03305 | | radical SAM family heme chaperone HemW | low | > 77 |
| Rhodanobacter denitrificans FW104-10B01 | 0.18 | LRK54_RS15135 | | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.26 | LRK54_RS11735 | | radical SAM family heme chaperone HemW | low | > 59 |
| Rhodanobacter denitrificans MT42 | 0.18 | LRK55_RS14850 | | NAD(P)H-hydrate dehydratase | 0.26 | LRK55_RS11460 | | radical SAM family heme chaperone HemW | low | > 63 |
| Shewanella amazonensis SB2B | 0.18 | Sama_3030 | | YjeF protein (RefSeq) | 0.26 | Sama_2483 | | oxygen-independent coproporphyrinogen III oxidase, putative (RefSeq) | low | > 62 |
| Alteromonas macleodii MIT1002 | 0.18 | MIT1002_03793 | | Nicotinamide nucleotide repair protein | 0.26 | MIT1002_00939 | | Oxygen-independent coproporphyrinogen-III oxidase 1 | low | > 70 |
| Bifidobacterium breve UCC2003 | 0.17 | BBR_RS15480 | | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.38 | BBR_RS15235 | | coproporphyrinogen III oxidase | low | > 34 |
| Paraburkholderia sabiae LMG 24235 | 0.17 | QEN71_RS21930 | | NAD(P)H-hydrate dehydratase | 0.25 | QEN71_RS03635 | | radical SAM family heme chaperone HemW | low | > 153 |
| Bacteroides stercoris CC31F | 0.17 | HMPREF1181_RS06260 | | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.29 | HMPREF1181_RS06440 | | radical SAM family heme chaperone HemW | low | > 56 |
| Shewanella loihica PV-4 | 0.17 | Shew_0561 | | carbohydrate kinase, YjeF-related protein (RefSeq) | 0.28 | Shew_1131 | | putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) | low | > 60 |
| Shewanella sp. ANA-3 | 0.17 | Shewana3_0592 | | carbohydrate kinase, YjeF related protein (RefSeq) | 0.26 | Shewana3_1188 | | putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) | low | > 73 |
| Parabacteroides merdae CL09T00C40 | 0.17 | HMPREF1078_RS15325 | | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.29 | HMPREF1078_RS11035 | | radical SAM family heme chaperone HemW | low | > 61 |
| Bacteroides ovatus ATCC 8483 | 0.17 | BACOVA_05215 | | YjeF domain protein | 0.25 | BACOVA_03177 | | putative oxygen-independent coproporphyrinogen III oxidase | low | > 94 |
| Rahnella sp. WP5 | 0.17 | EX31_RS08845 | | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.26 | EX31_RS02710 | | radical SAM family heme chaperone HemW | low | > 89 |
| Phocaeicola dorei CL03T12C01 | 0.16 | ABI39_RS08310 | | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.30 | ABI39_RS00100 | | radical SAM family heme chaperone HemW | low | > 72 |
| Phocaeicola vulgatus CL09T03C04 | 0.16 | HMPREF1058_RS00705 | | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.31 | HMPREF1058_RS07680 | | radical SAM family heme chaperone HemW | low | > 67 |
| Pseudomonas fluorescens FW300-N1B4 | 0.16 | Pf1N1B4_1417 | | NAD(P)HX epimerase / NAD(P)HX dehydratase | 0.26 | Pf1N1B4_2334 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | low | > 87 |
| Shewanella oneidensis MR-1 | 0.16 | SO0598 | yjeF | yjeF protein (NCBI ptt file) | 0.26 | SO3359 | | oxygen-independent coproporphyrinogen III oxidase, putative (NCBI ptt file) | low | > 76 |
| Rhodanobacter sp. FW510-T8 | 0.16 | OKGIIK_03905 | | Bifunctional NAD(P)H-hydrate repair enzyme | 0.26 | OKGIIK_12160 | hemW | radical SAM family heme chaperone HemW | low | > 52 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.16 | BT4383 | | putative sugar kinase (NCBI ptt file) | 0.30 | BT2168 | | coproporphyrinogen III oxidase (NCBI ptt file) | low | > 81 |
| Pseudomonas fluorescens FW300-N2E3 | 0.16 | AO353_13120 | | carbohydrate kinase | 0.26 | AO353_08200 | | coproporphyrinogen III oxidase | low | > 101 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.16 | CA265_RS24885 | | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.27 | CA265_RS18155 | | coproporphyrinogen III oxidase | low | > 88 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.16 | GFF820 | | NAD(P)HX epimerase / NAD(P)HX dehydratase | 0.26 | GFF3058 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | low | > 78 |
| Pectobacterium carotovorum WPP14 | 0.16 | HER17_RS02560 | | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.28 | HER17_RS03785 | | radical SAM family heme chaperone HemW | low | > 75 |
| Pseudomonas sp. RS175 | 0.16 | PFR28_05116 | | Bifunctional NAD(P)H-hydrate repair enzyme Nnr | 0.26 | PFR28_04249 | | Heme chaperone HemW | low | > 88 |
| Rhodopseudomonas palustris CGA009 | 0.15 | TX73_015380 | | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.26 | TX73_001700 | | radical SAM family heme chaperone HemW | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.15 | ABZR86_RS00840 | | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.25 | ABZR86_RS11910 | | radical SAM family heme chaperone HemW | low | > 74 |
| Magnetospirillum magneticum AMB-1 | 0.15 | AMB_RS14075 | | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.30 | AMB_RS22770 | | radical SAM protein | low | > 64 |
| Sinorhizobium meliloti 1021 | 0.15 | SMc00946 | | hypothetical protein | 0.26 | SMc01147 | | coproporphyrinogen III oxidase | 0.26 | 48 |
| Lysobacter sp. OAE881 | 0.15 | ABIE51_RS08050 | | NAD(P)H-hydrate dehydratase | 0.27 | ABIE51_RS17300 | | radical SAM family heme chaperone HemW | low | > 62 |
| Azospirillum sp. SherDot2 | 0.15 | MPMX19_01552 | | Bifunctional NAD(P)H-hydrate repair enzyme Nnr | 0.27 | MPMX19_02574 | | Heme chaperone HemW | low | > 112 |
| Pseudomonas fluorescens FW300-N2E2 | 0.15 | Pf6N2E2_3619 | | NAD(P)HX epimerase / NAD(P)HX dehydratase | 0.26 | Pf6N2E2_4593 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | low | > 103 |
| Pseudomonas sp. S08-1 | 0.15 | OH686_09495 | | NAD(P)H-hydrate epimerase / ADP-dependent (S)-NAD(P)H-hydrate dehydratase | 0.25 | OH686_11020 | | Oxygen-independent coproporphyrinogen-III oxidase-like protein YggW | low | > 80 |
| Escherichia fergusonii Becca | 0.15 | EFB2_04368 | | Bifunctional NAD(P)H-hydrate repair enzyme Nnr | 0.26 | EFB2_00947 | | Heme chaperone HemW | low | > 86 |
| Pseudomonas fluorescens GW456-L13 | 0.15 | PfGW456L13_159 | | NAD(P)HX epimerase / NAD(P)HX dehydratase | 0.25 | PfGW456L13_1003 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | low | > 87 |
| Serratia liquefaciens MT49 | 0.15 | IAI46_01600 | | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.25 | IAI46_21435 | | radical SAM family heme chaperone HemW | low | > 86 |
| Escherichia coli Nissle 1917 | 0.15 | ECOLIN_RS24205 | | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.26 | ECOLIN_RS16435 | | radical SAM family heme chaperone HemW | low | > 52 |
| Pseudomonas fluorescens FW300-N2C3 | 0.15 | AO356_08680 | | carbohydrate kinase | 0.26 | AO356_13390 | | coproporphyrinogen III oxidase | low | > 104 |
| Escherichia coli BW25113 | 0.15 | b4167 | yjeF | predicted carbohydrate kinase (NCBI) | 0.26 | b2955 | yggW | coproporphyrinogen III oxidase (NCBI) | low | > 76 |
| Pseudomonas stutzeri RCH2 | 0.15 | Psest_0678 | | yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region | 0.25 | Psest_0276 | | putative oxygen-independent coproporphyrinogen III oxidase | low | > 67 |
| Kangiella aquimarina DSM 16071 | 0.15 | B158DRAFT_1947 | | yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region | 0.25 | B158DRAFT_0201 | | coproporphyrinogen III oxidase, anaerobic (EC 1.3.99.22) | low | > 40 |
| Escherichia coli ECRC102 | 0.15 | NIAGMN_10130 | nnr | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.26 | NIAGMN_17000 | hemW | radical SAM family heme chaperone HemW | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.15 | OHPLBJKB_03875 | | Bifunctional NAD(P)H-hydrate repair enzyme Nnr | 0.26 | OHPLBJKB_00761 | | Oxygen-independent coproporphyrinogen-III oxidase-like protein YqeR | low | > 73 |
| Escherichia coli ECRC62 | 0.15 | BNILDI_06945 | nnr | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.26 | BNILDI_09685 | hemW | radical SAM family heme chaperone HemW | — | — |
| Escherichia coli ECRC99 | 0.15 | KEDOAH_15875 | nnr | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.26 | KEDOAH_08905 | hemW | radical SAM family heme chaperone HemW | — | — |
| Escherichia coli ECRC101 | 0.15 | OKFHMN_12280 | nnr | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.26 | OKFHMN_19235 | hemW | radical SAM family heme chaperone HemW | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.15 | Xcc-8004.2253.1 | | NAD(P)HX epimerase / NAD(P)HX dehydratase | 0.24 | Xcc-8004.1224.1 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | low | > 74 |
| Escherichia coli ECOR27 | 0.15 | NOLOHH_04545 | nnr | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.26 | NOLOHH_11105 | hemW | radical SAM family heme chaperone HemW | low | > 57 |
| Escherichia coli ECRC101 | 0.15 | MCAODC_02795 | nnr | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.26 | MCAODC_09755 | hemW | radical SAM family heme chaperone HemW | — | — |
| Dechlorosoma suillum PS | 0.15 | Dsui_2898 | | yjeF-like protein, hydroxyethylthiazole kinase-related protein | 0.29 | Dsui_0491 | | putative oxygen-independent coproporphyrinogen III oxidase | — | — |
| Escherichia coli ECRC98 | 0.15 | JDDGAC_15920 | nnr | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.26 | JDDGAC_22865 | hemW | radical SAM family heme chaperone HemW | — | — |
| Escherichia coli BL21 | 0.14 | ECD_04034 | | bifunctional NAD(P)H-hydrate repair enzyme; C-terminal domain ADP-dependent (S)-NAD(P)H-hydrate dehydratase and N-terminal domain NAD(P)H-hydrate epimerase | 0.26 | ECD_02785 | | HemN family putative oxidoreductase | low | > 60 |
| Escherichia coli ECOR38 | 0.14 | HEPCGN_10510 | nnr | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.26 | HEPCGN_18540 | hemW | radical SAM family heme chaperone HemW | 0.63 | 56 |
| Enterobacter asburiae PDN3 | 0.14 | EX28DRAFT_3364 | | yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region | 0.27 | EX28DRAFT_2993 | | putative oxygen-independent coproporphyrinogen III oxidase | low | > 76 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.14 | ABZR88_RS18865 | | NAD(P)H-hydrate dehydratase | 0.28 | ABZR88_RS03545 | | radical SAM family heme chaperone HemW | low | > 71 |
| Dinoroseobacter shibae DFL-12 | 0.14 | Dshi_1837 | | carbohydrate kinase, YjeF related protein (RefSeq) | 0.27 | Dshi_3460 | | putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) | low | > 64 |
| Enterobacter sp. TBS_079 | 0.14 | MPMX20_00448 | | Bifunctional NAD(P)H-hydrate repair enzyme Nnr | 0.27 | MPMX20_03813 | | Heme chaperone HemW | low | > 85 |
| Vibrio cholerae E7946 ATCC 55056 | 0.14 | CSW01_14940 | | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.28 | CSW01_02425 | | YggW family oxidoreductase | low | > 62 |
| Sphingomonas koreensis DSMZ 15582 | 0.13 | Ga0059261_0649 | | yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region | 0.23 | Ga0059261_2753 | | putative oxygen-independent coproporphyrinogen III oxidase | low | > 68 |
| Azospirillum brasilense Sp245 | 0.13 | AZOBR_RS07115 | | hypothetical protein | 0.28 | AZOBR_RS02195 | | coproporphyrinogen III oxidase | low | > 97 |
| Pseudomonas syringae pv. syringae B728a | 0.13 | Psyr_0567 | | Protein of unknown function UPF0031:YjeF-related protein, N-terminal | 0.24 | Psyr_0471 | | coproporphyrinogen III oxidase, anaerobic | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.13 | Psyr_0567 | | Protein of unknown function UPF0031:YjeF-related protein, N-terminal | 0.24 | Psyr_0471 | | coproporphyrinogen III oxidase, anaerobic | low | > 86 |
| Synechococcus elongatus PCC 7942 | 0.13 | Synpcc7942_1273 | | hypothetical protein | 0.23 | Synpcc7942_2382 | hemN | coproporphyrinogen III oxidase | low | > 38 |
| Marinobacter adhaerens HP15 | 0.13 | HP15_2504 | | carbohydrate kinase, YjeF related protein | 0.23 | HP15_280 | | putative oxygen-independent coproporphyrinogen III oxidase | low | > 73 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.12 | Echvi_0073 | | yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region | 0.27 | Echvi_0628 | | putative oxygen-independent coproporphyrinogen III oxidase | low | > 79 |
| Phaeobacter inhibens DSM 17395 | 0.12 | PGA1_c18700 | | yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region | 0.28 | PGA1_c35050 | | oxygen-independent coproporphyrinogen III oxidase HemN | low | > 62 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.12 | CA264_16280 | | bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase | 0.32 | CA264_16765 | | coproporphyrinogen III oxidase | low | > 74 |
| Acinetobacter radioresistens SK82 | 0.07 | MPMX26_01782 | | Bifunctional NAD(P)H-hydrate repair enzyme Nnr | 0.22 | MPMX26_00308 | | Heme chaperone HemW | — | — |
Not shown: 20 genomes with orthologs for Rv3433c only; 12 genomes with orthologs for Rv2388c only