Conservation of cofitness between QEN71_RS26595 and QEN71_RS04195 in Paraburkholderia sabiae LMG 24235

77 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Paraburkholderia sabiae LMG 24235 1.0 QEN71_RS26595 YggS family pyridoxal phosphate-dependent enzyme 1.0 QEN71_RS04195 Lrp/AsnC ligand binding domain-containing protein 0.49 13
Paraburkholderia graminis OAS925 0.87 ABIE53_000841 pyridoxal phosphate enzyme (YggS family) 0.95 ABIE53_003132 Lrp/AsnC family leucine-responsive transcriptional regulator low > 113
Paraburkholderia bryophila 376MFSha3.1 0.87 H281DRAFT_04680 hypothetical protein 0.95 H281DRAFT_04288 transcriptional regulator, AsnC family low > 103
Burkholderia phytofirmans PsJN 0.85 BPHYT_RS03495 hypothetical protein 0.93 BPHYT_RS14785 AsnC family transcriptional regulator low > 109
Ralstonia sp. UNC404CL21Col 0.63 ABZR87_RS01225 YggS family pyridoxal phosphate-dependent enzyme 0.81 ABZR87_RS09565 Lrp/AsnC ligand binding domain-containing protein low > 80
Variovorax sp. SCN45 0.62 GFF3744 Pyridoxal phosphate-containing protein YggS 0.64 GFF1774 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system
Herbaspirillum seropedicae SmR1 0.62 HSERO_RS18995 hypothetical protein 0.83 HSERO_RS08380 AsnC family transcriptional regulator low > 78
Pseudomonas sp. S08-1 0.62 OH686_10975 Pyridoxal phosphate-containing protein YggS 0.71 OH686_13680 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system low > 80
Cupriavidus basilensis FW507-4G11 0.61 RR42_RS17355 hypothetical protein 0.82 RR42_RS04590 AsnC family transcriptional regulator low > 128
Variovorax sp. OAS795 0.60 ABID97_RS00250 YggS family pyridoxal phosphate-dependent enzyme 0.63 ABID97_RS22380 winged helix-turn-helix transcriptional regulator
Ralstonia solanacearum UW163 0.60 UW163_RS08050 YggS family pyridoxal phosphate-dependent enzyme 0.81 UW163_RS15935 AsnC family transcriptional regulator
Ralstonia solanacearum IBSBF1503 0.60 RALBFv3_RS05575 YggS family pyridoxal phosphate-dependent enzyme 0.81 RALBFv3_RS13875 AsnC family transcriptional regulator low > 76
Ralstonia solanacearum GMI1000 0.60 RS_RS13435 YggS family pyridoxal phosphate-dependent enzyme 0.79 RS_RS04610 AsnC family transcriptional regulator low > 80
Ralstonia solanacearum PSI07 0.60 RPSI07_RS11725 YggS family pyridoxal phosphate-dependent enzyme 0.81 RPSI07_RS19595 AsnC family transcriptional regulator low > 81
Pseudomonas syringae pv. syringae B728a ΔmexB 0.59 Psyr_0477 Protein of unknown function UPF0001 0.69 Psyr_0234 transcriptional regulator, AsnC family low > 86
Pseudomonas syringae pv. syringae B728a 0.59 Psyr_0477 Protein of unknown function UPF0001 0.69 Psyr_0234 transcriptional regulator, AsnC family low > 86
Pseudomonas fluorescens SBW25 0.58 PFLU_RS28370 YggS family pyridoxal phosphate-dependent enzyme 0.69 PFLU_RS29385 AsnC family transcriptional regulator low > 109
Pseudomonas fluorescens SBW25-INTG 0.58 PFLU_RS28370 YggS family pyridoxal phosphate-dependent enzyme 0.69 PFLU_RS29385 AsnC family transcriptional regulator low > 109
Pseudomonas putida KT2440 0.58 PP_5094 putative enzyme with PLP binding domain 0.69 PP_5271 DNA-binding transcriptional dual regulator, leucine-binding low > 96
Pseudomonas simiae WCS417 0.58 PS417_26725 hypothetical protein 0.69 PS417_27710 AsnC family transcriptional regulator low > 88
Pseudomonas fluorescens FW300-N1B4 0.57 Pf1N1B4_2342 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC 0.69 Pf1N1B4_2143 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system
Pseudomonas fluorescens FW300-N2C3 0.57 AO356_13425 hypothetical protein 0.68 AO356_12615 AsnC family transcriptional regulator low > 104
Shewanella loihica PV-4 0.57 Shew_1137 alanine racemase domain-containing protein (RefSeq) 0.59 Shew_2025 leucine-responsive transcriptional regulator (RefSeq) low > 60
Pectobacterium carotovorum WPP14 0.57 HER17_RS03810 YggS family pyridoxal phosphate-dependent enzyme 0.57 HER17_RS12360 leucine-responsive transcriptional regulator Lrp low > 75
Pseudomonas fluorescens GW456-L13 0.56 PfGW456L13_1011 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC 0.69 PfGW456L13_811 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.56 GFF3054 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC 0.56 GFF4893 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system low > 78
Pseudomonas stutzeri RCH2 0.56 Psest_0284 pyridoxal phosphate enzyme, YggS family 0.67 Psest_3794 Transcriptional regulators low > 67
Pantoea sp. MT58 0.55 IAI47_03595 YggS family pyridoxal phosphate-dependent enzyme 0.56 IAI47_12915 leucine-responsive transcriptional regulator Lrp low > 76
Klebsiella michiganensis M5al 0.55 BWI76_RS24100 YggS family pyridoxal phosphate enzyme 0.56 BWI76_RS09655 leucine-responsive regulatory protein low > 92
Dickeya dianthicola ME23 0.55 DZA65_RS18435 YggS family pyridoxal phosphate-dependent enzyme 0.57 DZA65_RS09915 leucine-responsive transcriptional regulator Lrp low > 75
Pseudomonas sp. RS175 0.55 PFR28_04242 Pyridoxal phosphate homeostasis protein 0.69 PFR28_04400 Leucine-responsive regulatory protein 0.32 14
Dickeya dadantii 3937 0.55 DDA3937_RS17300 YggS family pyridoxal phosphate-dependent enzyme 0.57 DDA3937_RS09590 leucine-responsive transcriptional regulator Lrp low > 74
Enterobacter asburiae PDN3 0.54 EX28DRAFT_2989 pyridoxal phosphate enzyme, YggS family 0.56 EX28DRAFT_2043 transcriptional regulator, AsnC family low > 76
Shewanella oneidensis MR-1 0.54 SO3352 conserved hypothetical protein TIGR00044 (NCBI ptt file) 0.58 SO2305 lrp leucine-responsive regulatory protein (NCBI ptt file) low > 76
Pseudomonas fluorescens FW300-N2E2 0.54 Pf6N2E2_4601 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC 0.68 Pf6N2E2_4390 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system low > 103
Dickeya dianthicola 67-19 0.54 HGI48_RS17345 YggS family pyridoxal phosphate-dependent enzyme 0.57 HGI48_RS09605 leucine-responsive transcriptional regulator Lrp low > 71
Pseudomonas fluorescens FW300-N2E3 0.54 AO353_08160 hypothetical protein 0.69 AO353_09160 AsnC family transcriptional regulator low > 101
Escherichia fergusonii Becca 0.54 EFB2_00951 Pyridoxal phosphate homeostasis protein 0.56 EFB2_03172 Leucine-responsive regulatory protein low > 86
Shewanella sp. ANA-3 0.54 Shewana3_1194 hypothetical protein (RefSeq) 0.58 Shewana3_2049 leucine-responsive transcriptional regulator (RefSeq) low > 73
Escherichia coli HS(pFamp)R (ATCC 700891) 0.54 OHPLBJKB_00765 Pyridoxal phosphate homeostasis protein 0.56 OHPLBJKB_02779 Leucine-responsive regulatory protein 0.46 51
Escherichia coli Nissle 1917 0.54 ECOLIN_RS16415 pyridoxal phosphate homeostasis protein 0.56 ECOLIN_RS04730 leucine-responsive transcriptional regulator Lrp low > 55
Escherichia coli ECRC98 0.54 JDDGAC_22885 yggS pyridoxal phosphate homeostasis protein 0.56 JDDGAC_09385 lrp leucine-responsive transcriptional regulator Lrp low > 86
Escherichia coli ECRC100 0.54 OKFHMN_19255 yggS pyridoxal phosphate homeostasis protein 0.56 OKFHMN_05575 lrp leucine-responsive transcriptional regulator Lrp low > 80
Escherichia coli ECOR27 0.54 NOLOHH_11125 yggS pyridoxal phosphate homeostasis protein 0.56 NOLOHH_22145 lrp leucine-responsive transcriptional regulator Lrp low > 75
Escherichia coli BL21 0.54 ECD_02781 UPF0001 family protein, PLP-binding 0.56 ECD_00893 leucine-responsive global transcriptional regulator low > 61
Escherichia coli ECRC101 0.54 MCAODC_09775 yggS pyridoxal phosphate homeostasis protein 0.56 MCAODC_24965 lrp leucine-responsive transcriptional regulator Lrp low > 87
Escherichia coli ECOR38 0.54 HEPCGN_18560 yggS pyridoxal phosphate homeostasis protein 0.56 HEPCGN_22935 lrp leucine-responsive transcriptional regulator Lrp low > 87
Escherichia coli ECRC62 0.54 BNILDI_09705 yggS pyridoxal phosphate homeostasis protein 0.56 BNILDI_20400 lrp leucine-responsive transcriptional regulator Lrp low > 75
Escherichia coli ECRC102 0.54 NIAGMN_17020 yggS pyridoxal phosphate homeostasis protein 0.56 NIAGMN_03295 lrp leucine-responsive transcriptional regulator Lrp
Escherichia coli BW25113 0.54 b2951 yggS predicted enzyme (NCBI) 0.56 b0889 lrp DNA-binding transcriptional dual regulator, leucine-binding (NCBI) 0.26 14
Rahnella sp. WP5 0.53 EX31_RS02685 YggS family pyridoxal phosphate-dependent enzyme 0.56 EX31_RS18530 leucine-responsive transcriptional regulator Lrp low > 89
Acidovorax sp. GW101-3H11 0.53 Ac3H11_4474 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC 0.52 Ac3H11_2849 PutR, transcriptional activator of PutA and PutP low > 79
Escherichia coli ECRC99 0.53 KEDOAH_08885 yggS pyridoxal phosphate homeostasis protein 0.56 KEDOAH_22160 lrp leucine-responsive transcriptional regulator Lrp
Hydrogenophaga sp. GW460-11-11-14-LB1 0.53 GFF2722 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC 0.48 GFF2725 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.52 32
Erwinia tracheiphila SCR3 0.53 LU632_RS05460 YggS family pyridoxal phosphate-dependent enzyme 0.56 LU632_RS09740 lrp leucine-responsive transcriptional regulator Lrp 0.58 53
Enterobacter sp. TBS_079 0.53 MPMX20_03809 Pyridoxal phosphate homeostasis protein 0.56 MPMX20_01551 Leucine-responsive regulatory protein low > 85
Vibrio cholerae E7946 ATCC 55056 0.51 CSW01_02455 YggS family pyridoxal phosphate enzyme 0.57 CSW01_09530 leucine-responsive transcriptional regulator Lrp
Marinobacter adhaerens HP15 0.51 HP15_288 alanine racemase domain protein 0.41 HP15_2690 transcriptional regulator, AsnC family low > 73
Alteromonas macleodii MIT1002 0.50 MIT1002_03061 pyridoxal phosphate enzyme, YggS family 0.54 MIT1002_02181 Leucine-responsive regulatory protein low > 70
Shewanella amazonensis SB2B 0.50 Sama_2477 hypothetical protein (RefSeq) 0.60 Sama_1771 leucine-responsive transcriptional regulator (RefSeq) low > 62
Acinetobacter radioresistens SK82 0.49 MPMX26_02404 Pyridoxal phosphate homeostasis protein 0.46 MPMX26_01467 Leucine-responsive regulatory protein low > 36
Serratia liquefaciens MT49 0.49 IAI46_21410 YggS family pyridoxal phosphate-dependent enzyme 0.56 IAI46_08555 leucine-responsive transcriptional regulator Lrp low > 86
Kangiella aquimarina DSM 16071 0.42 B158DRAFT_0196 pyridoxal phosphate enzyme, YggS family 0.59 B158DRAFT_1822 Transcriptional regulators low > 40
Xanthomonas campestris pv. campestris strain 8004 0.40 Xcc-8004.1711.1 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC 0.65 Xcc-8004.4622.1 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system low > 74
Castellaniella sp019104865 MT123 0.34 ABCV34_RS02955 YggS family pyridoxal phosphate-dependent enzyme 0.67 ABCV34_RS10805 winged helix-turn-helix transcriptional regulator low > 48
Rhodanobacter denitrificans MT42 0.34 LRK55_RS08955 YggS family pyridoxal phosphate-dependent enzyme 0.66 LRK55_RS00365 winged helix-turn-helix transcriptional regulator low > 63
Agrobacterium fabrum C58 0.33 Atu2747 hypothetical protein 0.40 Atu4159 AsnC family transcriptional regulator low > 89
Rhodanobacter denitrificans FW104-10B01 0.33 LRK54_RS02905 YggS family pyridoxal phosphate-dependent enzyme 0.66 LRK54_RS00595 winged helix-turn-helix transcriptional regulator low > 59
Rhizobium sp. OAE497 0.31 ABIE40_RS19180 YggS family pyridoxal phosphate-dependent enzyme 0.36 ABIE40_RS23450 Lrp/AsnC family transcriptional regulator
Bosea sp. OAE506 0.31 ABIE41_RS04720 YggS family pyridoxal phosphate-dependent enzyme 0.49 ABIE41_RS07920 Lrp/AsnC ligand binding domain-containing protein low > 77
Azospirillum brasilense Sp245 0.31 AZOBR_RS01870 alanine racemase 0.51 AZOBR_RS23685 AsnC family transcriptional regulator
Rhodanobacter sp. FW510-T8 0.30 OKGIIK_09885 Pyridoxal phosphate homeostasis protein 0.65 OKGIIK_06660 lrp AsnC family transcriptional regulator low > 52
Azospirillum sp. SherDot2 0.30 MPMX19_00050 Pyridoxal phosphate homeostasis protein 0.44 MPMX19_03947 Leucine-responsive regulatory protein low > 112
Sinorhizobium meliloti 1021 0.29 SMc02812 hypothetical protein 0.48 SMc00681 leucine-responsive regulatory protein low > 103
Brevundimonas sp. GW460-12-10-14-LB2 0.29 A4249_RS13760 YggS family pyridoxal phosphate-dependent enzyme 0.50 A4249_RS13055 Lrp/AsnC ligand binding domain-containing protein low > 48
Bacteroides stercoris CC31F 0.28 HMPREF1181_RS10865 YggS family pyridoxal phosphate-dependent enzyme 0.26 HMPREF1181_RS01345 Lrp/AsnC ligand binding domain-containing protein low > 56
Caulobacter crescentus NA1000 Δfur 0.27 CCNA_03861 pyridoxal 5'-phosphate dependent enzyme class III 0.48 CCNA_00847 leucine-responsive regulatory protein low > 67
Caulobacter crescentus NA1000 0.27 CCNA_03861 pyridoxal 5'-phosphate dependent enzyme class III 0.48 CCNA_00847 leucine-responsive regulatory protein low > 66

Not shown: 24 genomes with orthologs for QEN71_RS26595 only; 0 genomes with orthologs for QEN71_RS04195 only