Conservation of cofitness between PP_0366 and PP_4782 in Pseudomonas putida KT2440

72 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_0366 dethiobiotin synthetase 1.0 PP_4782 Phosphomethylpyrimidine kinase 0.43 16
Pseudomonas fluorescens GW456-L13 0.79 PfGW456L13_1151 Dethiobiotin synthetase (EC 6.3.3.3) 0.87 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 87
Pseudomonas fluorescens FW300-N1B4 0.78 Pf1N1B4_2491 Dethiobiotin synthetase (EC 6.3.3.3) 0.78 Pf1N1B4_2718 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 87
Pseudomonas fluorescens FW300-N2C3 0.77 AO356_14155 dethiobiotin synthetase 0.88 AO356_15435 hydrogenase low > 104
Pseudomonas fluorescens SBW25 0.77 PFLU_RS27630 dethiobiotin synthase 0.88 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 109
Pseudomonas fluorescens SBW25-INTG 0.77 PFLU_RS27630 dethiobiotin synthase 0.88 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.24 94
Pseudomonas sp. RS175 0.77 PFR28_04099 ATP-dependent dethiobiotin synthetase BioD 1 0.84 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Pseudomonas fluorescens FW300-N2E2 0.77 Pf6N2E2_4764 Dethiobiotin synthetase (EC 6.3.3.3) 0.78 Pf6N2E2_5024 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 103
Pseudomonas fluorescens FW300-N2E3 0.77 AO353_07505 dethiobiotin synthetase 0.87 AO353_06350 hydrogenase low > 101
Pseudomonas simiae WCS417 0.76 PS417_25985 dethiobiotin synthetase 0.87 PS417_24600 hydrogenase low > 88
Pseudomonas syringae pv. syringae B728a 0.72 Psyr_4683 dethiobiotin synthase 0.85 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.70 5
Pseudomonas syringae pv. syringae B728a ΔmexB 0.72 Psyr_4683 dethiobiotin synthase 0.85 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.52 11
Pseudomonas sp. S08-1 0.72 OH686_10335 dethiobiotin synthase 0.82 OH686_09185 Hydroxymethylpyrimidine phosphate kinase ThiD low > 80
Pseudomonas stutzeri RCH2 0.62 Psest_0415 dethiobiotin synthase 0.78 Psest_0537 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 67
Marinobacter adhaerens HP15 0.49 HP15_2482 dethiobiotin synthetase 0.27 HP15_349 phosphomethylpyrimidine kinase — —
Pantoea sp. MT58 0.47 IAI47_13515 ATP-dependent dethiobiotin synthetase BioD 0.20 IAI47_06810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Dickeya dianthicola 67-19 0.47 HGI48_RS08690 ATP-dependent dethiobiotin synthetase BioD 0.22 HGI48_RS15410 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 71
Dickeya dianthicola ME23 0.47 DZA65_RS08980 ATP-dependent dethiobiotin synthetase BioD 0.22 DZA65_RS16235 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.57 13
Dyella japonica UNC79MFTsu3.2 0.46 ABZR86_RS12700 dethiobiotin synthase 0.23 ABZR86_RS00760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Enterobacter asburiae PDN3 0.46 EX28DRAFT_2213 dethiobiotin synthase 0.22 EX28DRAFT_0469 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Vibrio cholerae E7946 ATCC 55056 0.45 CSW01_05660 dethiobiotin synthase 0.22 CSW01_06545 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 62
Enterobacter sp. TBS_079 0.45 MPMX20_01406 ATP-dependent dethiobiotin synthetase BioD 1 0.24 MPMX20_03076 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.22 38
Serratia liquefaciens MT49 0.45 IAI46_06540 ATP-dependent dethiobiotin synthetase BioD 0.24 IAI46_19100 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 86
Dickeya dadantii 3937 0.45 DDA3937_RS08525 ATP-dependent dethiobiotin synthetase BioD 0.23 DDA3937_RS15335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 74
Klebsiella michiganensis M5al 0.44 BWI76_RS08775 dethiobiotin synthase 0.24 BWI76_RS19375 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 92
Escherichia coli Nissle 1917 0.44 ECOLIN_RS04145 dethiobiotin synthase 0.23 ECOLIN_RS12335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia fergusonii Becca 0.44 EFB2_03327 ATP-dependent dethiobiotin synthetase BioD 1 0.23 EFB2_01754 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 86
Escherichia coli BL21 0.44 ECD_00745 dethiobiotin synthetase 0.24 ECD_02031 hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase low > 60
Escherichia coli ECRC101 0.44 MCAODC_25600 bioD dethiobiotin synthase 0.24 MCAODC_21085 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC98 0.44 JDDGAC_10020 bioD dethiobiotin synthase 0.24 JDDGAC_28185 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC99 0.44 KEDOAH_21525 bioD dethiobiotin synthase 0.24 KEDOAH_04075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.44 OHPLBJKB_02935 ATP-dependent dethiobiotin synthetase BioD 1 0.24 OHPLBJKB_01607 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 73
Escherichia coli BW25113 0.44 b0778 bioD dethiobiotin synthetase (NCBI) 0.24 b2103 thiD phosphomethylpyrimidine kinase (NCBI) 0.23 21
Pectobacterium carotovorum WPP14 0.44 HER17_RS13445 dethiobiotin synthase 0.25 HER17_RS06265 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Escherichia coli ECRC101 0.44 OKFHMN_06385 bioD dethiobiotin synthase 0.24 OKFHMN_24075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC102 0.44 NIAGMN_04430 bioD dethiobiotin synthase 0.24 NIAGMN_22020 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECOR27 0.44 NOLOHH_22755 bioD dethiobiotin synthase 0.24 NOLOHH_15415 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 57
Dechlorosoma suillum PS 0.43 Dsui_2884 dethiobiotin synthase 0.40 Dsui_0662 phosphomethylpyrimidine kinase — —
Escherichia coli ECRC62 0.43 BNILDI_21025 bioD dethiobiotin synthase 0.24 BNILDI_14330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECOR38 0.43 HEPCGN_01655 bioD dethiobiotin synthase 0.23 HEPCGN_02760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 85
Erwinia tracheiphila SCR3 0.43 LU632_RS09145 bioD dethiobiotin synthase 0.23 LU632_RS08590 thiD bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Lysobacter sp. OAE881 0.42 ABIE51_RS17990 dethiobiotin synthase 0.23 ABIE51_RS07970 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.42 GFF3994 Dethiobiotin synthetase (EC 6.3.3.3) 0.24 GFF249 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.42 GFF674 Dethiobiotin synthetase (EC 6.3.3.3) 0.23 GFF3834 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 78
Rhodanobacter sp. FW510-T8 0.42 OKGIIK_16455 bioD dethiobiotin synthase 0.22 OKGIIK_03835 Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 52
Rahnella sp. WP5 0.41 EX31_RS23710 ATP-dependent dethiobiotin synthetase BioD 0.23 EX31_RS20390 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 89
Herbaspirillum seropedicae SmR1 0.37 HSERO_RS12255 dethiobiotin synthetase 0.31 HSERO_RS02135 phosphomethylpyrimidine kinase low > 78
Variovorax sp. OAS795 0.37 ABID97_RS16255 dethiobiotin synthase 0.19 ABID97_RS15330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Burkholderia phytofirmans PsJN 0.37 BPHYT_RS02155 dithiobiotin synthetase 0.19 BPHYT_RS04205 kinase low > 109
Variovorax sp. SCN45 0.36 GFF143 Dethiobiotin synthase BioD (EC 6.3.3.3) 0.16 GFF2149 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 127
Ralstonia solanacearum UW163 0.35 UW163_RS14160 dethiobiotin synthase 0.26 UW163_RS03675 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum IBSBF1503 0.35 RALBFv3_RS00825 dethiobiotin synthase 0.26 RALBFv3_RS09905 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Acidovorax sp. GW101-3H11 0.35 Ac3H11_3829 Dethiobiotin synthetase (EC 6.3.3.3) 0.21 Ac3H11_1063 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) — —
Paraburkholderia bryophila 376MFSha3.1 0.34 H281DRAFT_02096 dethiobiotin synthetase 0.22 H281DRAFT_04811 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 103
Paraburkholderia graminis OAS925 0.34 ABIE53_000578 dethiobiotin synthetase 0.22 ABIE53_001125 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 113
Ralstonia sp. UNC404CL21Col 0.33 ABZR87_RS12345 dethiobiotin synthase 0.24 ABZR87_RS04830 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum PSI07 0.33 RPSI07_RS16695 dethiobiotin synthase 0.26 RPSI07_RS23455 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Xanthomonas campestris pv. campestris strain 8004 0.33 Xcc-8004.4530.1 Dethiobiotin synthetase (EC 6.3.3.3) 0.23 Xcc-8004.3091.1 hypothetical protein low > 74
Ralstonia solanacearum GMI1000 0.32 RS_RS07440 ATP-dependent dethiobiotin synthetase BioD 0.26 RS_RS00495 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Paraburkholderia sabiae LMG 24235 0.32 QEN71_RS01090 dethiobiotin synthase 0.19 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Cupriavidus basilensis FW507-4G11 0.28 RR42_RS00935 dethiobiotin synthetase 0.19 RR42_RS01370 phosphomethylpyrimidine kinase — —
Parabacteroides merdae CL09T00C40 0.18 HMPREF1078_RS15275 dethiobiotin synthase 0.26 HMPREF1078_RS03470 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 61
Desulfovibrio vulgaris Miyazaki F 0.17 DvMF_1009 dethiobiotin synthase (RefSeq) 0.20 DvMF_1376 phosphomethylpyrimidine kinase (RefSeq) — —
Rhizobium sp. OAE497 0.15 ABIE40_RS21065 dethiobiotin synthase 0.27 ABIE40_RS25930 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 107
Bacteroides stercoris CC31F 0.15 HMPREF1181_RS15515 ATP-dependent dethiobiotin synthetase BioD 0.24 HMPREF1181_RS14705 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Synechococcus elongatus PCC 7942 0.15 Synpcc7942_0030 bioD dethiobiotin synthase 0.17 Synpcc7942_2379 thiD phosphomethylpyrimidine kinase — —
Pedobacter sp. GW460-11-11-14-LB5 0.14 CA265_RS09760 dethiobiotin synthase 0.19 CA265_RS24160 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 88
Castellaniella sp019104865 MT123 0.14 ABCV34_RS15285 dethiobiotin synthase 0.22 ABCV34_RS14505 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Bacteroides ovatus ATCC 8483 0.14 BACOVA_00874 dethiobiotin synthase 0.26 BACOVA_02530 phosphomethylpyrimidine kinase low > 94
Agrobacterium fabrum C58 0.14 Atu3999 dithiobiotin synthetase 0.25 Atu3290 phosphomethylpyrimidine kinase 0.65 7
Bacteroides thetaiotaomicron VPI-5482 0.13 BT1446 dethiobiotin synthetase (NCBI ptt file) 0.29 BT0790 phosphomethylpyrimidine kinase (NCBI ptt file) low > 81
Phaeobacter inhibens DSM 17395 0.13 PGA1_c09140 dethiobiotin synthetase BioD 0.17 PGA1_c09030 phosphomethylpyrimidine kinase ThiD 0.26 56
Pontibacter actiniarum KMM 6156, DSM 19842 0.12 CA264_02415 dethiobiotin synthase 0.20 CA264_20430 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 74

Not shown: 10 genomes with orthologs for PP_0366 only; 21 genomes with orthologs for PP_4782 only